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The map label for this gene is sdhB [H]

Identifier: 74317203

GI number: 74317203

Start: 1244928

End: 1245623

Strand: Direct

Name: sdhB [H]

Synonym: Tbd_1185

Alternate gene names: 74317203

Gene position: 1244928-1245623 (Clockwise)

Preceding gene: 74317202

Following gene: 74317204

Centisome position: 42.78

GC content: 65.37

Gene sequence:

>696_bases
ATGAAATTCCGCGTCTACCGCTACTCTCCGGAGTCCGGCAAAAAACCCTTCATGCAGGACGTCGAGCTCGACATCGACCC
GGCCGGCAAGATGCTGCTCGACGCGCTGCTCGCGATCAAGGCTCAGGACGAAACTTTGTCGTTGCGCCGCTCGTGCCGCG
AGGGCGTGTGCGGGTCCGACGCGATGAACGTCAACGGCAGGAACCGGCTCGCCTGCATCACGCCCTTGTCCGAACTGAAG
GAGCCGATCGAGGTGCGGCCGCTGCCGGGGCTGCCCGTGATCCGCGATCTCGTCGTCGACATGGAGCCGTTCTACAGGCA
GTACCGCTCGATCAAGCCCTGGCTCATCAACGACGATCCCGAGCCCGAAGTCGAGCGCATGCAGAGCCCGGAAGACCGCG
GGCTGCTCGACGGCGCCTACGAATGCATCCTGTGCGCCTGCTGCACGTCGTCGTGTCCCTCGTACTGGTGGAACCCGGAG
AAGTTCGTCGGCCCAGCCGGACTGCTGCAGGCCTACCGCTTCATCGCCGACTCGCGCGACGAAGCGACCGCAGCGCGCCT
CGACAACCTCGAGGATCCCTACCGGCTGTATCGTTGCCGCGGCATCATGAACTGTGTCGACGTCTGCCCCAAGGGCCTCA
ACCCTGCGGGGGCGATCGCGCGGATCCGCACGCTGCTGGCCAAACGCCGTGTCTGA

Upstream 100 bases:

>100_bases
AGGGTGTATTGATGGTTCAGGGGCGGGTTAAGCAACGGGCGAAACGCGAAGCCATTGCCCATACTGGACGGCATTCACGG
CGTTGGCGTAGGACGCCGAT

Downstream 100 bases:

>100_bases
GTCACGGCCGGCGGTGGATGATGCCGAAGGCGCAGGGGGAAATTTTCCCGACGACGCGGGCAACCTGCAAAGCGCCCGGA
TCGCCTGGCGCTGCCGTCGC

Product: succinate dehydrogenase subunit B

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 231; Mature: 231

Protein sequence:

>231_residues
MKFRVYRYSPESGKKPFMQDVELDIDPAGKMLLDALLAIKAQDETLSLRRSCREGVCGSDAMNVNGRNRLACITPLSELK
EPIEVRPLPGLPVIRDLVVDMEPFYRQYRSIKPWLINDDPEPEVERMQSPEDRGLLDGAYECILCACCTSSCPSYWWNPE
KFVGPAGLLQAYRFIADSRDEATAARLDNLEDPYRLYRCRGIMNCVDVCPKGLNPAGAIARIRTLLAKRRV

Sequences:

>Translated_231_residues
MKFRVYRYSPESGKKPFMQDVELDIDPAGKMLLDALLAIKAQDETLSLRRSCREGVCGSDAMNVNGRNRLACITPLSELK
EPIEVRPLPGLPVIRDLVVDMEPFYRQYRSIKPWLINDDPEPEVERMQSPEDRGLLDGAYECILCACCTSSCPSYWWNPE
KFVGPAGLLQAYRFIADSRDEATAARLDNLEDPYRLYRCRGIMNCVDVCPKGLNPAGAIARIRTLLAKRRV
>Mature_231_residues
MKFRVYRYSPESGKKPFMQDVELDIDPAGKMLLDALLAIKAQDETLSLRRSCREGVCGSDAMNVNGRNRLACITPLSELK
EPIEVRPLPGLPVIRDLVVDMEPFYRQYRSIKPWLINDDPEPEVERMQSPEDRGLLDGAYECILCACCTSSCPSYWWNPE
KFVGPAGLLQAYRFIADSRDEATAARLDNLEDPYRLYRCRGIMNCVDVCPKGLNPAGAIARIRTLLAKRRV

Specific function: Two Distinct, Membrane-Bound, FAD-Containing Enzymes Are Responsible For The Catalysis Of Fumarate And Succinate Interconversion; The Fumarate Reductase Is Used In Anaerobic Growth, And The Succinate Dehydrogenase Is Used In Aerobic Growth. [C]

COG id: COG0479

COG function: function code C; Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 4Fe-4S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI115387094, Length=231, Percent_Identity=54.1125541125541, Blast_Score=258, Evalue=4e-69,
Organism=Escherichia coli, GI1786943, Length=236, Percent_Identity=59.3220338983051, Blast_Score=294, Evalue=4e-81,
Organism=Escherichia coli, GI1790596, Length=230, Percent_Identity=36.5217391304348, Blast_Score=137, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17533915, Length=230, Percent_Identity=50.8695652173913, Blast_Score=249, Evalue=8e-67,
Organism=Saccharomyces cerevisiae, GI6322987, Length=229, Percent_Identity=53.7117903930131, Blast_Score=252, Evalue=4e-68,
Organism=Drosophila melanogaster, GI17137106, Length=233, Percent_Identity=55.793991416309, Blast_Score=270, Evalue=5e-73,
Organism=Drosophila melanogaster, GI24643156, Length=229, Percent_Identity=55.4585152838428, Blast_Score=261, Evalue=3e-70,

Paralogues:

None

Copy number: 480 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006058
- InterPro:   IPR017896
- InterPro:   IPR017900
- InterPro:   IPR012675
- InterPro:   IPR001041
- InterPro:   IPR012285
- InterPro:   IPR009051
- InterPro:   IPR004489 [H]

Pfam domain/function: NA

EC number: =1.3.99.1 [H]

Molecular weight: Translated: 26177; Mature: 26177

Theoretical pI: Translated: 6.47; Mature: 6.47

Prosite motif: PS51085 2FE2S_FER_2 ; PS00198 4FE4S_FERREDOXIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

4.8 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
7.8 %Cys+Met (Translated Protein)
4.8 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
7.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFRVYRYSPESGKKPFMQDVELDIDPAGKMLLDALLAIKAQDETLSLRRSCREGVCGSD
CCEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
AMNVNGRNRLACITPLSELKEPIEVRPLPGLPVIRDLVVDMEPFYRQYRSIKPWLINDDP
CCCCCCCCCEEEECCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCC
EPEVERMQSPEDRGLLDGAYECILCACCTSSCPSYWWNPEKFVGPAGLLQAYRFIADSRD
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCC
EATAARLDNLEDPYRLYRCRGIMNCVDVCPKGLNPAGAIARIRTLLAKRRV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKFRVYRYSPESGKKPFMQDVELDIDPAGKMLLDALLAIKAQDETLSLRRSCREGVCGSD
CCEEEEEECCCCCCCCCHHHCCCCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHCCCCCCC
AMNVNGRNRLACITPLSELKEPIEVRPLPGLPVIRDLVVDMEPFYRQYRSIKPWLINDDP
CCCCCCCCCEEEECCHHHHCCCCEECCCCCCHHHHHHHHHHHHHHHHHHCCCCEEECCCC
EPEVERMQSPEDRGLLDGAYECILCACCTSSCPSYWWNPEKFVGPAGLLQAYRFIADSRD
CHHHHHHCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCCHHHHCCHHHHHHHHHHHHCCCC
EATAARLDNLEDPYRLYRCRGIMNCVDVCPKGLNPAGAIARIRTLLAKRRV
HHHHHHHCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA