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The map label for this gene is suhB [H]

Identifier: 74317178

GI number: 74317178

Start: 1214967

End: 1215773

Strand: Reverse

Name: suhB [H]

Synonym: Tbd_1160

Alternate gene names: 74317178

Gene position: 1215773-1214967 (Counterclockwise)

Preceding gene: 74317189

Following gene: 74317177

Centisome position: 41.78

GC content: 63.32

Gene sequence:

>807_bases
ATGCATCCCATGCTCAATACGGCGGTGAAAGCCGCACGCAAGGCGGGGGCGATCATCAATCGCGCCTCGCTCGACCTCGA
CCAACTCACCGTACGGAGCAAGCAGGACCGCGATTACGTCAGCGAAGTCGACCAGATGGCCGAACGCGCCATCATCGAAA
CGCTGCTCGACGCCTATCCGAACCACGGGATTCTAGCAGAGGAGTCTGGCAGCACCGACGCCAAGAACGGCGAAGACTAC
CAGTGGATCATCGATCCGCTCGACGGCACGACCAACTTCCTGCATGGCCTGCCGCAGTATTCCGTGTCGATCGCGCTGAA
GCACAAGGGCCAGATCACCCAGGCCGTCGTGTTCGATCCCTCGCGCAACGAACTCTTCACCGCGAGCCGCGGCCGCGGTG
CGATGCTCAACGACCGGCGGATCCGTGCGAGCAAGCGCAGCAAACTCTCCGAGTGCCTGATCGGCACCGGCTTTCCCTAC
TGCGAGTTCAGCTACGCCGAGGCCTACATCAACATGTTCCGCGAGATGATGCGCGCGACCTCCGGGTTGCGTCGGCCCGG
TTCGGCCGCACTTGATCTTGCCTACGTCGCCTGCGGCCGTTACGACGGGTTCTGGGAAATCCGTCTCAAGCCCTGGGATC
TCGCGGCCGGCAGCCTGATCGCCCAGGAATCGGGCGCGCTCGTCGGCAACCTGGTCGGTGACGAAGGCTTCCTCGAGTCC
GGCAATATCGTCGCCGCGAGCCCGAAAGTCTTCGCGCAGATGCTGCAACTGATCGCGCCGCATCTGCCGCCCGAACTCAA
GGTCTGA

Upstream 100 bases:

>100_bases
TGCGCGCGAGCACCACGCGAATGTCGGCGAGAAGTTTAGGATCGCTCGATGTCATCAAGTAAAATGGCGCGCTCGTTCTT
TGAATCCATTGCCAGACATC

Downstream 100 bases:

>100_bases
ATTCGCGTCTCCCCATGTCGATCGCGCCCGCGGCCCACACGCCGATGATGCAGCAGTATCTCGGCATCAAGGCACAGCAT
CCCGACATGCTGCTGTTCTA

Product: inositol monophosphatase

Products: NA

Alternate protein names: I-1-Pase; IMPase; Inositol-1-phosphatase [H]

Number of amino acids: Translated: 268; Mature: 268

Protein sequence:

>268_residues
MHPMLNTAVKAARKAGAIINRASLDLDQLTVRSKQDRDYVSEVDQMAERAIIETLLDAYPNHGILAEESGSTDAKNGEDY
QWIIDPLDGTTNFLHGLPQYSVSIALKHKGQITQAVVFDPSRNELFTASRGRGAMLNDRRIRASKRSKLSECLIGTGFPY
CEFSYAEAYINMFREMMRATSGLRRPGSAALDLAYVACGRYDGFWEIRLKPWDLAAGSLIAQESGALVGNLVGDEGFLES
GNIVAASPKVFAQMLQLIAPHLPPELKV

Sequences:

>Translated_268_residues
MHPMLNTAVKAARKAGAIINRASLDLDQLTVRSKQDRDYVSEVDQMAERAIIETLLDAYPNHGILAEESGSTDAKNGEDY
QWIIDPLDGTTNFLHGLPQYSVSIALKHKGQITQAVVFDPSRNELFTASRGRGAMLNDRRIRASKRSKLSECLIGTGFPY
CEFSYAEAYINMFREMMRATSGLRRPGSAALDLAYVACGRYDGFWEIRLKPWDLAAGSLIAQESGALVGNLVGDEGFLES
GNIVAASPKVFAQMLQLIAPHLPPELKV
>Mature_268_residues
MHPMLNTAVKAARKAGAIINRASLDLDQLTVRSKQDRDYVSEVDQMAERAIIETLLDAYPNHGILAEESGSTDAKNGEDY
QWIIDPLDGTTNFLHGLPQYSVSIALKHKGQITQAVVFDPSRNELFTASRGRGAMLNDRRIRASKRSKLSECLIGTGFPY
CEFSYAEAYINMFREMMRATSGLRRPGSAALDLAYVACGRYDGFWEIRLKPWDLAAGSLIAQESGALVGNLVGDEGFLES
GNIVAASPKVFAQMLQLIAPHLPPELKV

Specific function: Unknown

COG id: COG0483

COG function: function code G; Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the inositol monophosphatase family [H]

Homologues:

Organism=Homo sapiens, GI7657236, Length=262, Percent_Identity=33.587786259542, Blast_Score=142, Evalue=3e-34,
Organism=Homo sapiens, GI5031789, Length=253, Percent_Identity=29.2490118577075, Blast_Score=132, Evalue=3e-31,
Organism=Homo sapiens, GI221625487, Length=255, Percent_Identity=29.0196078431373, Blast_Score=132, Evalue=5e-31,
Organism=Homo sapiens, GI221625507, Length=144, Percent_Identity=32.6388888888889, Blast_Score=94, Evalue=1e-19,
Organism=Escherichia coli, GI1788882, Length=267, Percent_Identity=48.689138576779, Blast_Score=266, Evalue=1e-72,
Organism=Escherichia coli, GI1790659, Length=132, Percent_Identity=31.0606060606061, Blast_Score=64, Evalue=2e-11,
Organism=Caenorhabditis elegans, GI193202570, Length=271, Percent_Identity=31.3653136531365, Blast_Score=135, Evalue=3e-32,
Organism=Caenorhabditis elegans, GI193202572, Length=238, Percent_Identity=33.6134453781513, Blast_Score=134, Evalue=4e-32,
Organism=Saccharomyces cerevisiae, GI6320493, Length=210, Percent_Identity=38.5714285714286, Blast_Score=130, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6321836, Length=233, Percent_Identity=28.755364806867, Blast_Score=94, Evalue=2e-20,
Organism=Drosophila melanogaster, GI21357329, Length=264, Percent_Identity=31.8181818181818, Blast_Score=135, Evalue=2e-32,
Organism=Drosophila melanogaster, GI24664922, Length=231, Percent_Identity=33.3333333333333, Blast_Score=134, Evalue=7e-32,
Organism=Drosophila melanogaster, GI21357303, Length=250, Percent_Identity=33.2, Blast_Score=130, Evalue=6e-31,
Organism=Drosophila melanogaster, GI24664926, Length=226, Percent_Identity=31.4159292035398, Blast_Score=121, Evalue=6e-28,
Organism=Drosophila melanogaster, GI24664918, Length=203, Percent_Identity=33.0049261083744, Blast_Score=110, Evalue=1e-24,
Organism=Drosophila melanogaster, GI21357957, Length=239, Percent_Identity=30.5439330543933, Blast_Score=104, Evalue=5e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020583
- InterPro:   IPR000760
- InterPro:   IPR020550
- InterPro:   IPR022337 [H]

Pfam domain/function: PF00459 Inositol_P [H]

EC number: =3.1.3.25 [H]

Molecular weight: Translated: 29466; Mature: 29466

Theoretical pI: Translated: 6.37; Mature: 6.37

Prosite motif: PS00629 IMP_1 ; PS00630 IMP_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MHPMLNTAVKAARKAGAIINRASLDLDQLTVRSKQDRDYVSEVDQMAERAIIETLLDAYP
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NHGILAEESGSTDAKNGEDYQWIIDPLDGTTNFLHGLPQYSVSIALKHKGQITQAVVFDP
CCCEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEECCCCEEEEEEECC
SRNELFTASRGRGAMLNDRRIRASKRSKLSECLIGTGFPYCEFSYAEAYINMFREMMRAT
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SGLRRPGSAALDLAYVACGRYDGFWEIRLKPWDLAAGSLIAQESGALVGNLVGDEGFLES
HCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCCC
GNIVAASPKVFAQMLQLIAPHLPPELKV
CCEEEECHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure
MHPMLNTAVKAARKAGAIINRASLDLDQLTVRSKQDRDYVSEVDQMAERAIIETLLDAYP
CCCHHHHHHHHHHHHHHHHHHCCCCHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCC
NHGILAEESGSTDAKNGEDYQWIIDPLDGTTNFLHGLPQYSVSIALKHKGQITQAVVFDP
CCCEEECCCCCCCCCCCCCCEEEEECCCCHHHHHHCCCCCEEEEEEECCCCEEEEEEECC
SRNELFTASRGRGAMLNDRRIRASKRSKLSECLIGTGFPYCEFSYAEAYINMFREMMRAT
CCCCEEECCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHHH
SGLRRPGSAALDLAYVACGRYDGFWEIRLKPWDLAAGSLIAQESGALVGNLVGDEGFLES
HCCCCCCCHHHHHHHHHHCCCCCEEEEEEECCCCCCCHHHHHCCCCEEEEECCCCCCCCC
GNIVAASPKVFAQMLQLIAPHLPPELKV
CCEEEECHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10761919 [H]