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The map label for this gene is ihfA

Identifier: 74317031

GI number: 74317031

Start: 1082656

End: 1082967

Strand: Direct

Name: ihfA

Synonym: Tbd_1013

Alternate gene names: 74317031

Gene position: 1082656-1082967 (Clockwise)

Preceding gene: 74317030

Following gene: 74317032

Centisome position: 37.21

GC content: 58.97

Gene sequence:

>312_bases
ATGACGACTCTCACCAAAGCTGATCTGGCCGAACTGCTGTTCGAAAAAGTGGGCTTGAACAAACGCGAGGCGAAGGACGT
CGTCGAATCGTTTTTCGATGAAATCCGTCTCGCGCTCGAGAAGGGCGACATCGTCAAGCTCTCGGGCTTCGGCAACTTCC
AGTGTCGCGAGAAGCCGCAGCGCCCCGGACGCAATCCGAAGACCGGCGAGGAAATGCCGATCTCGGCTCGCCGCGTGGTG
ACCTTCCACGCCAGTCAGAAACTCAAGTCGCAGGTCGAAGGCGCCCGAATTGGAACGCCCAGCCAAGAGTGA

Upstream 100 bases:

>100_bases
GACGAAGCGGTGCAGAAACTGGTCGACGCCGCCGCCCGTCGGTGCAGCGCCACGCTGCGCGCATGACTGATTTTTCACCT
GCCATTGCGGCCTCTACACC

Downstream 100 bases:

>100_bases
ACTCCCGCCGATTCCGGCGAAACGCTATTTCACGATCGGTGAAGTCTCCGAGCTGTGCGCCGTCAAGGCGCACGTGCTGC
GTTACTGGGAGCAGGAATTC

Product: integration host factor subunit alpha

Products: NA

Alternate protein names: IHF-alpha

Number of amino acids: Translated: 103; Mature: 102

Protein sequence:

>103_residues
MTTLTKADLAELLFEKVGLNKREAKDVVESFFDEIRLALEKGDIVKLSGFGNFQCREKPQRPGRNPKTGEEMPISARRVV
TFHASQKLKSQVEGARIGTPSQE

Sequences:

>Translated_103_residues
MTTLTKADLAELLFEKVGLNKREAKDVVESFFDEIRLALEKGDIVKLSGFGNFQCREKPQRPGRNPKTGEEMPISARRVV
TFHASQKLKSQVEGARIGTPSQE
>Mature_102_residues
TTLTKADLAELLFEKVGLNKREAKDVVESFFDEIRLALEKGDIVKLSGFGNFQCREKPQRPGRNPKTGEEMPISARRVVT
FHASQKLKSQVEGARIGTPSQE

Specific function: This protein is one of the two subunits of integration host factor, a specific DNA-binding protein that functions in genetic recombination as well as in transcriptional and translational control

COG id: COG0776

COG function: function code L; Bacterial nucleoid DNA-binding protein

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the bacterial histone-like protein family

Homologues:

Organism=Escherichia coli, GI1788005, Length=93, Percent_Identity=68.8172043010753, Blast_Score=132, Evalue=4e-33,
Organism=Escherichia coli, GI1790433, Length=90, Percent_Identity=38.8888888888889, Blast_Score=69, Evalue=4e-14,
Organism=Escherichia coli, GI1786644, Length=90, Percent_Identity=33.3333333333333, Blast_Score=62, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): IHFA_THIDA (Q3SK28)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314771.1
- HSSP:   P0A6X7
- ProteinModelPortal:   Q3SK28
- SMR:   Q3SK28
- STRING:   Q3SK28
- GeneID:   3671237
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_1013
- NMPDR:   fig|292415.3.peg.743
- eggNOG:   COG0776
- HOGENOM:   HBG705085
- OMA:   VRGETVK
- PhylomeDB:   Q3SK28
- ProtClustDB:   PRK00285
- BioCyc:   TDEN292415:TBD_1013-MONOMER
- GO:   GO:0006350
- HAMAP:   MF_00380
- InterPro:   IPR000119
- InterPro:   IPR020816
- InterPro:   IPR010992
- InterPro:   IPR005684
- Gene3D:   G3DSA:4.10.520.10
- PRINTS:   PR01727
- SMART:   SM00411
- TIGRFAMs:   TIGR00987

Pfam domain/function: PF00216 Bac_DNA_binding; SSF47729 IHF_like_DNA_bnd

EC number: NA

Molecular weight: Translated: 11532; Mature: 11401

Theoretical pI: Translated: 9.88; Mature: 9.88

Prosite motif: PS00045 HISTONE_LIKE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.0 %Cys     (Translated Protein)
1.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
1.0 %Cys     (Mature Protein)
1.0 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTLTKADLAELLFEKVGLNKREAKDVVESFFDEIRLALEKGDIVKLSGFGNFQCREKPQ
CCCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
RPGRNPKTGEEMPISARRVVTFHASQKLKSQVEGARIGTPSQE
CCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHCCCCCCCCCCC
>Mature Secondary Structure 
TTLTKADLAELLFEKVGLNKREAKDVVESFFDEIRLALEKGDIVKLSGFGNFQCREKPQ
CCCCHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHCCCCEEEECCCCCCCCCCCCC
RPGRNPKTGEEMPISARRVVTFHASQKLKSQVEGARIGTPSQE
CCCCCCCCCCCCCCCCHHEEEEHHHHHHHHHHCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA