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The map label for this gene is yciR [C]

Identifier: 74317013

GI number: 74317013

Start: 1061004

End: 1063292

Strand: Reverse

Name: yciR [C]

Synonym: Tbd_0995

Alternate gene names: 74317013

Gene position: 1063292-1061004 (Counterclockwise)

Preceding gene: 74317014

Following gene: 74317010

Centisome position: 36.54

GC content: 65.44

Gene sequence:

>2289_bases
TTGAAGGCGGACAGTCTGTCGGTCAAGCACGTCGCGCTCGCCTTCATCGCGGGGCTGCTCGTGCTCGTCAGCCTGATCGG
CGGATTTGCCGCCTACCAGACCCGATCGGTCACGCGCAGCCTGGAACTGCACAACGAGAATGCGGCACGCTCCGAACTCG
TCGCGGCGGTCCAGCGACTGCTGGACCAGACCAAGGCCCAGGCCGACGCCCTCGCGCAATGGGATGAGACCCGCCAGCAA
CTGGTGTTGCCCGAGTACTACACCTACTGGCGGGATCAGCGCGTCTACGAGAGCGGGATGCTGCCGGCACGTTTCACGCG
CGCGGGCCTCTATACGCGCGGGCGCGCCCTGCTCGCGCCGAACTCCTCGAAGAGCACGCTGCCGGCGGTGCTGCCAGCGG
ACATCGCGCTCCACGAACGGGCGAGCTGGCTCGCGAGCGAAAACGGCATGACGGCGCTCTATCACGCCTTCCCGGTCTAC
GGCGACGATCAGCGGGAATCCCTGCTCGGCTACGGTGTGATCCGCGTCGAGTTCATGCCCATGCTGCTGAGTCAGGATCG
GCTGTATTTCGTCGACGTTCCGAGCGTGAAACTGGCGCTGAAACCGGGCGAAGTGCTGCCCGCCTCGCAGCTCTTCTCGC
ACCTGCGCTACAGCGCACGCCCCGATCCCGAGCAGAAGCGCTTCCAGACGATCCTGTCGCGCACACTGCTGGCGCTTTTC
GCGCTCCTGCTGCTTACCGCGCTGCTCGGTTTCGTCGCGTACAACCGGCTGCTGGTACGTCCCCTGCGACACCTGTCGAA
GGACATCGACGCCATGCAGCAGGGCCGTTTCAGCGCCCAGCCGGCCCGCTTCGAGTCGATGCGGATCCGCGAGCTCGAGA
ACATCCGCCGGTCACTCTACGACTATCAGTTGCAGCTGCGCGAACTGCACGGCTCGCTCGAAGACCAGAATCGCGAGTTT
CATTCGCAGGCGCGCCAGGACGCCCTTACGGGCTGCCACAACCGTCGCGCCTACGAGGAGGACTGGGAGACCTTCCGTCG
CGACCTCAAGAACGCACCGCAGGGCGTCGCCTTCCTGCTCTTCGACTGCGACCGCTTCAAGGCCATCAACGATACCTACG
GCCATGCCAAAGGCGACCGCGTGCTGACGATCATCGCCGACGCGCTGGTCATGGCCCTGCGCGCCAACGACCGCCTGTAT
CGCCTCGGCGGCGACGAGTTCGCGACCTTTCTTTCGCGCACGACGCCCGGCCAGGCGAAGCAGATCGCGCAGCGCTGCCA
GAGCCTGCTCGACGCGTCGGCCTTCAGCGAGCTCGGCATCAGCGAGCCGGTCGGCATCAGCATCGGCATCGCGTTCTGCG
GACCCGAGCACGCCGAGCAGATCGACGAGTTGCCCAAGCACGCCGACATCGCGATGTATACCGCCAAGCAGCCGGGGCGC
AACCGCATCGCGCTTTATGGCGAAGACACCGAGCGCGCGGCGCAGGCGCTGGTCGCGAGCCGGGAAACCAACGCCCTGTT
CCAGGCATTGTCGACCCCCGGCATGGTGGAGATGCATTACCAGTCGATCCACAGCCTGCCGGGACGCAAGATCGATTATT
ACGAGGCCCTCGCGCGCATCCGCTACAACGGCGAACTGATCATGCCGGACGCCTTTCTTCCGGTCATCAACAACCGCCGC
CTCGAAACCGAGTTCGACCTTGCGGTGCTCGCCCAGGTCGACGCCGATCTCTCCTCGCAACGGCTGCCGGCCGGAATCGG
CATCTCGTTCAATCTCTCGGCGCAAAGCCTGTCGCGTGCCGAGGTCGTCTCGCTCCTGCTCGAATTGTCGCGCCACATTC
CGCGCCATCCGCTCATGCTCGAGATCACCGAAACCTCGCTGATCACGCAGATGGCCGAGGTCAGCACCTATCTCGACCTG
CTGCGCACCGTGCACTACCGAATCGCGATGGACGATTTCGGCACCGGTTACTCGCCGCTGCGCTATCTGGTCGACCTGCC
GGTCGACGTGGTGAAGTTCGACATTTCGCTGGTCAGCAAGCTCGCCCAGGACAATCGGGCGGGCCAGGTCGTCGCAGATT
TCGCCCGCATGATGAGCGAAGCCGGCTATTCACTGGTCGCCGAGGGCGTCGAGACCGACGCCGTTCTGCGCAAGGTGGAA
AGCCTCGGCGTCGAGCACGTGCAGGGCTATCTCCTGAGCCGGCCCCTGCCGCTCGACAAACTGGCGAACGCGGGCGCCGC
GCAGGAGCGCGTCGCCGAATCCGCCGAGGTCGCGTCAGTGCTTCCCTGA

Upstream 100 bases:

>100_bases
TCGTGCCCGGCGCCAGCCACTTCATGGACGGGACCCACGAGTTCGAACTGCTCGAGCTCACGCAGCGCTTCCTCGAAGCG
CCCGAGCGGAGGCCCGCACG

Downstream 100 bases:

>100_bases
ACGCCAGATCGACAGCACGATCCACACGCTGTTGAAAAACGCGATCAGAAACCCGACCAGCCCGAAGAACGGCAGCCCGA
ACAGCTCCGGACCACCCTTG

Product: diguanylate cyclase/phosphodiesterase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 762; Mature: 762

Protein sequence:

>762_residues
MKADSLSVKHVALAFIAGLLVLVSLIGGFAAYQTRSVTRSLELHNENAARSELVAAVQRLLDQTKAQADALAQWDETRQQ
LVLPEYYTYWRDQRVYESGMLPARFTRAGLYTRGRALLAPNSSKSTLPAVLPADIALHERASWLASENGMTALYHAFPVY
GDDQRESLLGYGVIRVEFMPMLLSQDRLYFVDVPSVKLALKPGEVLPASQLFSHLRYSARPDPEQKRFQTILSRTLLALF
ALLLLTALLGFVAYNRLLVRPLRHLSKDIDAMQQGRFSAQPARFESMRIRELENIRRSLYDYQLQLRELHGSLEDQNREF
HSQARQDALTGCHNRRAYEEDWETFRRDLKNAPQGVAFLLFDCDRFKAINDTYGHAKGDRVLTIIADALVMALRANDRLY
RLGGDEFATFLSRTTPGQAKQIAQRCQSLLDASAFSELGISEPVGISIGIAFCGPEHAEQIDELPKHADIAMYTAKQPGR
NRIALYGEDTERAAQALVASRETNALFQALSTPGMVEMHYQSIHSLPGRKIDYYEALARIRYNGELIMPDAFLPVINNRR
LETEFDLAVLAQVDADLSSQRLPAGIGISFNLSAQSLSRAEVVSLLLELSRHIPRHPLMLEITETSLITQMAEVSTYLDL
LRTVHYRIAMDDFGTGYSPLRYLVDLPVDVVKFDISLVSKLAQDNRAGQVVADFARMMSEAGYSLVAEGVETDAVLRKVE
SLGVEHVQGYLLSRPLPLDKLANAGAAQERVAESAEVASVLP

Sequences:

>Translated_762_residues
MKADSLSVKHVALAFIAGLLVLVSLIGGFAAYQTRSVTRSLELHNENAARSELVAAVQRLLDQTKAQADALAQWDETRQQ
LVLPEYYTYWRDQRVYESGMLPARFTRAGLYTRGRALLAPNSSKSTLPAVLPADIALHERASWLASENGMTALYHAFPVY
GDDQRESLLGYGVIRVEFMPMLLSQDRLYFVDVPSVKLALKPGEVLPASQLFSHLRYSARPDPEQKRFQTILSRTLLALF
ALLLLTALLGFVAYNRLLVRPLRHLSKDIDAMQQGRFSAQPARFESMRIRELENIRRSLYDYQLQLRELHGSLEDQNREF
HSQARQDALTGCHNRRAYEEDWETFRRDLKNAPQGVAFLLFDCDRFKAINDTYGHAKGDRVLTIIADALVMALRANDRLY
RLGGDEFATFLSRTTPGQAKQIAQRCQSLLDASAFSELGISEPVGISIGIAFCGPEHAEQIDELPKHADIAMYTAKQPGR
NRIALYGEDTERAAQALVASRETNALFQALSTPGMVEMHYQSIHSLPGRKIDYYEALARIRYNGELIMPDAFLPVINNRR
LETEFDLAVLAQVDADLSSQRLPAGIGISFNLSAQSLSRAEVVSLLLELSRHIPRHPLMLEITETSLITQMAEVSTYLDL
LRTVHYRIAMDDFGTGYSPLRYLVDLPVDVVKFDISLVSKLAQDNRAGQVVADFARMMSEAGYSLVAEGVETDAVLRKVE
SLGVEHVQGYLLSRPLPLDKLANAGAAQERVAESAEVASVLP
>Mature_762_residues
MKADSLSVKHVALAFIAGLLVLVSLIGGFAAYQTRSVTRSLELHNENAARSELVAAVQRLLDQTKAQADALAQWDETRQQ
LVLPEYYTYWRDQRVYESGMLPARFTRAGLYTRGRALLAPNSSKSTLPAVLPADIALHERASWLASENGMTALYHAFPVY
GDDQRESLLGYGVIRVEFMPMLLSQDRLYFVDVPSVKLALKPGEVLPASQLFSHLRYSARPDPEQKRFQTILSRTLLALF
ALLLLTALLGFVAYNRLLVRPLRHLSKDIDAMQQGRFSAQPARFESMRIRELENIRRSLYDYQLQLRELHGSLEDQNREF
HSQARQDALTGCHNRRAYEEDWETFRRDLKNAPQGVAFLLFDCDRFKAINDTYGHAKGDRVLTIIADALVMALRANDRLY
RLGGDEFATFLSRTTPGQAKQIAQRCQSLLDASAFSELGISEPVGISIGIAFCGPEHAEQIDELPKHADIAMYTAKQPGR
NRIALYGEDTERAAQALVASRETNALFQALSTPGMVEMHYQSIHSLPGRKIDYYEALARIRYNGELIMPDAFLPVINNRR
LETEFDLAVLAQVDADLSSQRLPAGIGISFNLSAQSLSRAEVVSLLLELSRHIPRHPLMLEITETSLITQMAEVSTYLDL
LRTVHYRIAMDDFGTGYSPLRYLVDLPVDVVKFDISLVSKLAQDNRAGQVVADFARMMSEAGYSLVAEGVETDAVLRKVE
SLGVEHVQGYLLSRPLPLDKLANAGAAQERVAESAEVASVLP

Specific function: Unknown

COG id: COG5001

COG function: function code T; Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 MHYT domain [H]

Homologues:

Organism=Escherichia coli, GI1787541, Length=424, Percent_Identity=29.7169811320755, Blast_Score=141, Evalue=2e-34,
Organism=Escherichia coli, GI87082096, Length=434, Percent_Identity=28.3410138248848, Blast_Score=127, Evalue=4e-30,
Organism=Escherichia coli, GI1788381, Length=439, Percent_Identity=27.1070615034169, Blast_Score=123, Evalue=4e-29,
Organism=Escherichia coli, GI226510982, Length=543, Percent_Identity=27.0718232044199, Blast_Score=114, Evalue=2e-26,
Organism=Escherichia coli, GI1788849, Length=364, Percent_Identity=28.2967032967033, Blast_Score=103, Evalue=4e-23,
Organism=Escherichia coli, GI87081881, Length=187, Percent_Identity=35.8288770053476, Blast_Score=100, Evalue=4e-22,
Organism=Escherichia coli, GI87081743, Length=229, Percent_Identity=33.6244541484716, Blast_Score=100, Evalue=5e-22,
Organism=Escherichia coli, GI87081921, Length=446, Percent_Identity=24.8878923766816, Blast_Score=99, Evalue=1e-21,
Organism=Escherichia coli, GI1786507, Length=203, Percent_Identity=33.4975369458128, Blast_Score=96, Evalue=6e-21,
Organism=Escherichia coli, GI1786584, Length=174, Percent_Identity=33.3333333333333, Blast_Score=95, Evalue=2e-20,
Organism=Escherichia coli, GI145693134, Length=362, Percent_Identity=25.6906077348066, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1787816, Length=167, Percent_Identity=35.3293413173653, Blast_Score=93, Evalue=7e-20,
Organism=Escherichia coli, GI1787262, Length=164, Percent_Identity=32.3170731707317, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1788502, Length=229, Percent_Identity=31.0043668122271, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87081845, Length=230, Percent_Identity=31.304347826087, Blast_Score=90, Evalue=6e-19,
Organism=Escherichia coli, GI87081974, Length=156, Percent_Identity=32.0512820512821, Blast_Score=85, Evalue=2e-17,
Organism=Escherichia coli, GI87082007, Length=165, Percent_Identity=33.3333333333333, Blast_Score=83, Evalue=6e-17,
Organism=Escherichia coli, GI1788956, Length=223, Percent_Identity=31.390134529148, Blast_Score=82, Evalue=2e-16,
Organism=Escherichia coli, GI1790496, Length=224, Percent_Identity=25.8928571428571, Blast_Score=79, Evalue=1e-15,
Organism=Escherichia coli, GI1788085, Length=165, Percent_Identity=30.9090909090909, Blast_Score=76, Evalue=8e-15,
Organism=Escherichia coli, GI87081980, Length=233, Percent_Identity=26.6094420600858, Blast_Score=72, Evalue=9e-14,
Organism=Escherichia coli, GI1787056, Length=166, Percent_Identity=32.5301204819277, Blast_Score=72, Evalue=2e-13,
Organism=Escherichia coli, GI1787802, Length=169, Percent_Identity=27.810650887574, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1789650, Length=442, Percent_Identity=20.1357466063348, Blast_Score=69, Evalue=2e-12,
Organism=Escherichia coli, GI87081977, Length=175, Percent_Identity=29.7142857142857, Blast_Score=68, Evalue=3e-12,
Organism=Escherichia coli, GI1787055, Length=132, Percent_Identity=33.3333333333333, Blast_Score=67, Evalue=6e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001054
- InterPro:   IPR000160
- InterPro:   IPR001633
- InterPro:   IPR005330 [H]

Pfam domain/function: PF00563 EAL; PF00990 GGDEF; PF03707 MHYT [H]

EC number: NA

Molecular weight: Translated: 85172; Mature: 85172

Theoretical pI: Translated: 6.43; Mature: 6.43

Prosite motif: PS50885 HAMP ; PS50883 EAL ; PS50887 GGDEF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKADSLSVKHVALAFIAGLLVLVSLIGGFAAYQTRSVTRSLELHNENAARSELVAAVQRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LDQTKAQADALAQWDETRQQLVLPEYYTYWRDQRVYESGMLPARFTRAGLYTRGRALLAP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCEEECC
NSSKSTLPAVLPADIALHERASWLASENGMTALYHAFPVYGDDQRESLLGYGVIRVEFMP
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHEECCCCCCCHHHHHHHCCHHHHHHHH
MLLSQDRLYFVDVPSVKLALKPGEVLPASQLFSHLRYSARPDPEQKRFQTILSRTLLALF
HHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ALLLLTALLGFVAYNRLLVRPLRHLSKDIDAMQQGRFSAQPARFESMRIRELENIRRSLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
DYQLQLRELHGSLEDQNREFHSQARQDALTGCHNRRAYEEDWETFRRDLKNAPQGVAFLL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEE
FDCDRFKAINDTYGHAKGDRVLTIIADALVMALRANDRLYRLGGDEFATFLSRTTPGQAK
EECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCHHH
QIAQRCQSLLDASAFSELGISEPVGISIGIAFCGPEHAEQIDELPKHADIAMYTAKQPGR
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCC
NRIALYGEDTERAAQALVASRETNALFQALSTPGMVEMHYQSIHSLPGRKIDYYEALARI
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCCHHHHHHHHH
RYNGELIMPDAFLPVINNRRLETEFDLAVLAQVDADLSSQRLPAGIGISFNLSAQSLSRA
HCCCCEECCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHH
EVVSLLLELSRHIPRHPLMLEITETSLITQMAEVSTYLDLLRTVHYRIAMDDFGTGYSPL
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
RYLVDLPVDVVKFDISLVSKLAQDNRAGQVVADFARMMSEAGYSLVAEGVETDAVLRKVE
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
SLGVEHVQGYLLSRPLPLDKLANAGAAQERVAESAEVASVLP
HHCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MKADSLSVKHVALAFIAGLLVLVSLIGGFAAYQTRSVTRSLELHNENAARSELVAAVQRL
CCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
LDQTKAQADALAQWDETRQQLVLPEYYTYWRDQRVYESGMLPARFTRAGLYTRGRALLAP
HHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCHHHHHHCHHHCCCEEECC
NSSKSTLPAVLPADIALHERASWLASENGMTALYHAFPVYGDDQRESLLGYGVIRVEFMP
CCCCCCCCCCCCCHHHHHHHHHHHHCCCCCEEEHEECCCCCCCHHHHHHHCCHHHHHHHH
MLLSQDRLYFVDVPSVKLALKPGEVLPASQLFSHLRYSARPDPEQKRFQTILSRTLLALF
HHHCCCCEEEEECCCEEEEECCCCCCCHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHH
ALLLLTALLGFVAYNRLLVRPLRHLSKDIDAMQQGRFSAQPARFESMRIRELENIRRSLY
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHH
DYQLQLRELHGSLEDQNREFHSQARQDALTGCHNRRAYEEDWETFRRDLKNAPQGVAFLL
HHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCCCEEEEE
FDCDRFKAINDTYGHAKGDRVLTIIADALVMALRANDRLYRLGGDEFATFLSRTTPGQAK
EECHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCEEEECCHHHHHHHHCCCCCHHH
QIAQRCQSLLDASAFSELGISEPVGISIGIAFCGPEHAEQIDELPKHADIAMYTAKQPGR
HHHHHHHHHHHHHHHHHCCCCCCCCEEEEEEECCCHHHHHHHHCCCCCCEEEEECCCCCC
NRIALYGEDTERAAQALVASRETNALFQALSTPGMVEMHYQSIHSLPGRKIDYYEALARI
CEEEEECCCHHHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHHHCCCCCCCHHHHHHHHH
RYNGELIMPDAFLPVINNRRLETEFDLAVLAQVDADLSSQRLPAGIGISFNLSAQSLSRA
HCCCCEECCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCCCCCCCCCEEEECCHHHHHHH
EVVSLLLELSRHIPRHPLMLEITETSLITQMAEVSTYLDLLRTVHYRIAMDDFGTGYSPL
HHHHHHHHHHHCCCCCCEEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCCHHHH
RYLVDLPVDVVKFDISLVSKLAQDNRAGQVVADFARMMSEAGYSLVAEGVETDAVLRKVE
HHHHHCCHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCCHHHHHCCCHHHHHHHHHH
SLGVEHVQGYLLSRPLPLDKLANAGAAQERVAESAEVASVLP
HHCHHHHHHHHHCCCCCHHHHHCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]