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The map label for this gene is yfbQ [H]

Identifier: 74316860

GI number: 74316860

Start: 891010

End: 892290

Strand: Direct

Name: yfbQ [H]

Synonym: Tbd_0842

Alternate gene names: 74316860

Gene position: 891010-892290 (Clockwise)

Preceding gene: 74316858

Following gene: 74316861

Centisome position: 30.62

GC content: 64.48

Gene sequence:

>1281_bases
TTGTTTTGCCTTGAATTTACCCACTGGGAAATCGCCGTGACGGCCGACAAGAAGCCCCGCTTACGCACCATCCAGAAATC
GACCAAGCTCGACAACGTCTGCTACGACATCCGCGGGCCGGTCATGGCGCGCGCGCGCCAGATGGAGGAGGAGGGGCAGC
GCATCATCAAGCTGAACATCGGCAATCCTGCGCCGTTCGGCTTCGAGGCGCCCGAGGAGATCGTGCAGGACGTGATCCTC
AACCTGCCCAATGCCTCCGGCTACAGCGATTCGAAGGGCCTGTTCGCCGCGCGCAAGGCGATCATGCACGAAACCCAGCG
CAAGGGCATCGCCGGCGTGACGATCGACGACATCATCGTCGGCAACGGCGTGTCCGAACTGATCGTGATGGCGATGCAGG
CGCTGCTCAACAACGGCGACGAGGTGCTCGTGCCGGCGCCTGACTACCCGCTGTGGACGGCGGCCGTCAGCCTCGGCGGC
GGTAAGCCGCGCCACTACCTGTGCGACGAGGGCGCCGGCTGGCTACCCGACCTCGACGACATCCGCGCCAAGATCACGCC
CAGCACGCGCGCCATCGTCATCATCAACCCCAACAATCCGACCGGCGCGCTCTACCCGACCGAATTGCTGCGCGAAATCC
TCGAAATCGCGCGCCAGCACCAACTCATCGTCTACGCCGACGAAATCTACGACAAGGTGTTGTTCGACGGCGTCGTCCAC
ACCTCGATCGCCTCGCTCGCCGACGATCTCCTGATCGTCACGTTTAACGGCCTGTCGAAGAACTACCGTGCCTGCGGCTA
CCGCTCGGGCTGGCTCGTCGTCTCCGGCGACAAGCGCCACGCCAAGGATTATCTCGAAGGCCTCAACATGCTCGCGTCGA
TGCGGCTGTGCTCGAACGTGCCCGGCCAGCATGCGATCCAGACCGCGCTCGGCGGCTACCAGAGCATCAACGACCTCGTC
GCGCCGAGCGGGCGGCTGACGCGGCAGCGCGACCTCGCGCACGAACTCCTGACGCTGATTCCGGGCGTGAGCTGCGTCAA
GCCCAAGGCCGCGATGTACCTGTTCCCGCGGCTCGACCCCAAGCTCTACCCGATCCACGACGACCAGAAGTTCATCCTCA
ATCTGCTCGAGGAAGAGCGCGTGCTCGTCGTGCAGGGCACGGGCTTCAACTGGCCGCGGCCCGATCATCTGCGCGTCGTG
TTCCTGCCGCACGAAGAGGATTTGACCGAGGCGATCGGACGCATGAGCCGTTTCCTCGATCGCCAGCGCGCGCATCGCTG
A

Upstream 100 bases:

>100_bases
AGATTCGGCTTCCGCCCGAGCGTTGCGAAGCGCCCCGCCGGACGCGGTTTCGTTTGCCCGCGCAGGGCCCGTCCGGTAAA
ATCGCGCGTTTTACAAGGCT

Downstream 100 bases:

>100_bases
CTTTTACCGGAACCAGACGAGAACAATGAAGCCCATCCATGTCGGCCTCCTAGGCCTTGGAACCGTCGGCGGCGGCACGC
TCACCGTGCTGCGCCGCAAC

Product: aminotransferase AlaT

Products: oxaloacetate; L-glutamate

Alternate protein names: NA

Number of amino acids: Translated: 426; Mature: 426

Protein sequence:

>426_residues
MFCLEFTHWEIAVTADKKPRLRTIQKSTKLDNVCYDIRGPVMARARQMEEEGQRIIKLNIGNPAPFGFEAPEEIVQDVIL
NLPNASGYSDSKGLFAARKAIMHETQRKGIAGVTIDDIIVGNGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLGG
GKPRHYLCDEGAGWLPDLDDIRAKITPSTRAIVIINPNNPTGALYPTELLREILEIARQHQLIVYADEIYDKVLFDGVVH
TSIASLADDLLIVTFNGLSKNYRACGYRSGWLVVSGDKRHAKDYLEGLNMLASMRLCSNVPGQHAIQTALGGYQSINDLV
APSGRLTRQRDLAHELLTLIPGVSCVKPKAAMYLFPRLDPKLYPIHDDQKFILNLLEEERVLVVQGTGFNWPRPDHLRVV
FLPHEEDLTEAIGRMSRFLDRQRAHR

Sequences:

>Translated_426_residues
MFCLEFTHWEIAVTADKKPRLRTIQKSTKLDNVCYDIRGPVMARARQMEEEGQRIIKLNIGNPAPFGFEAPEEIVQDVIL
NLPNASGYSDSKGLFAARKAIMHETQRKGIAGVTIDDIIVGNGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLGG
GKPRHYLCDEGAGWLPDLDDIRAKITPSTRAIVIINPNNPTGALYPTELLREILEIARQHQLIVYADEIYDKVLFDGVVH
TSIASLADDLLIVTFNGLSKNYRACGYRSGWLVVSGDKRHAKDYLEGLNMLASMRLCSNVPGQHAIQTALGGYQSINDLV
APSGRLTRQRDLAHELLTLIPGVSCVKPKAAMYLFPRLDPKLYPIHDDQKFILNLLEEERVLVVQGTGFNWPRPDHLRVV
FLPHEEDLTEAIGRMSRFLDRQRAHR
>Mature_426_residues
MFCLEFTHWEIAVTADKKPRLRTIQKSTKLDNVCYDIRGPVMARARQMEEEGQRIIKLNIGNPAPFGFEAPEEIVQDVIL
NLPNASGYSDSKGLFAARKAIMHETQRKGIAGVTIDDIIVGNGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLGG
GKPRHYLCDEGAGWLPDLDDIRAKITPSTRAIVIINPNNPTGALYPTELLREILEIARQHQLIVYADEIYDKVLFDGVVH
TSIASLADDLLIVTFNGLSKNYRACGYRSGWLVVSGDKRHAKDYLEGLNMLASMRLCSNVPGQHAIQTALGGYQSINDLV
APSGRLTRQRDLAHELLTLIPGVSCVKPKAAMYLFPRLDPKLYPIHDDQKFILNLLEEERVLVVQGTGFNWPRPDHLRVV
FLPHEEDLTEAIGRMSRFLDRQRAHR

Specific function: Unknown

COG id: COG0436

COG function: function code E; Aspartate/tyrosine/aromatic aminotransferase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family [H]

Homologues:

Organism=Homo sapiens, GI19263340, Length=477, Percent_Identity=25.9958071278826, Blast_Score=138, Evalue=8e-33,
Organism=Homo sapiens, GI4507369, Length=380, Percent_Identity=28.9473684210526, Blast_Score=137, Evalue=1e-32,
Organism=Homo sapiens, GI215599424, Length=368, Percent_Identity=27.445652173913, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI4885351, Length=448, Percent_Identity=27.0089285714286, Blast_Score=125, Evalue=7e-29,
Organism=Homo sapiens, GI95147551, Length=168, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI169881279, Length=168, Percent_Identity=28.5714285714286, Blast_Score=87, Evalue=3e-17,
Organism=Homo sapiens, GI56713254, Length=167, Percent_Identity=25.1497005988024, Blast_Score=73, Evalue=5e-13,
Organism=Homo sapiens, GI56713256, Length=167, Percent_Identity=25.1497005988024, Blast_Score=72, Evalue=7e-13,
Organism=Homo sapiens, GI169881281, Length=143, Percent_Identity=27.2727272727273, Blast_Score=71, Evalue=2e-12,
Organism=Escherichia coli, GI1788627, Length=399, Percent_Identity=66.6666666666667, Blast_Score=579, Evalue=1e-166,
Organism=Escherichia coli, GI1788722, Length=407, Percent_Identity=27.7641277641278, Blast_Score=119, Evalue=3e-28,
Organism=Escherichia coli, GI1786816, Length=255, Percent_Identity=26.2745098039216, Blast_Score=86, Evalue=6e-18,
Organism=Caenorhabditis elegans, GI17567663, Length=414, Percent_Identity=30.1932367149758, Blast_Score=167, Evalue=9e-42,
Organism=Caenorhabditis elegans, GI71981209, Length=469, Percent_Identity=25.1599147121535, Blast_Score=120, Evalue=2e-27,
Organism=Caenorhabditis elegans, GI71981215, Length=294, Percent_Identity=26.1904761904762, Blast_Score=89, Evalue=4e-18,
Organism=Caenorhabditis elegans, GI71994472, Length=204, Percent_Identity=30.3921568627451, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI71994476, Length=204, Percent_Identity=30.3921568627451, Blast_Score=86, Evalue=4e-17,
Organism=Caenorhabditis elegans, GI17567369, Length=172, Percent_Identity=27.906976744186, Blast_Score=79, Evalue=4e-15,
Organism=Saccharomyces cerevisiae, GI6320317, Length=471, Percent_Identity=26.963906581741, Blast_Score=140, Evalue=4e-34,
Organism=Saccharomyces cerevisiae, GI6323118, Length=472, Percent_Identity=26.271186440678, Blast_Score=136, Evalue=8e-33,
Organism=Saccharomyces cerevisiae, GI6322401, Length=237, Percent_Identity=25.3164556962025, Blast_Score=91, Evalue=4e-19,
Organism=Drosophila melanogaster, GI18859735, Length=374, Percent_Identity=28.8770053475936, Blast_Score=162, Evalue=6e-40,
Organism=Drosophila melanogaster, GI24641770, Length=479, Percent_Identity=25.4697286012526, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641760, Length=479, Percent_Identity=25.4697286012526, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641768, Length=479, Percent_Identity=25.4697286012526, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641766, Length=479, Percent_Identity=25.4697286012526, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI24641764, Length=479, Percent_Identity=25.4697286012526, Blast_Score=125, Evalue=7e-29,
Organism=Drosophila melanogaster, GI45551451, Length=479, Percent_Identity=25.4697286012526, Blast_Score=125, Evalue=8e-29,
Organism=Drosophila melanogaster, GI28573069, Length=166, Percent_Identity=25.9036144578313, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI24646114, Length=166, Percent_Identity=25.9036144578313, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573067, Length=166, Percent_Identity=25.9036144578313, Blast_Score=78, Evalue=1e-14,
Organism=Drosophila melanogaster, GI28573065, Length=166, Percent_Identity=25.9036144578313, Blast_Score=78, Evalue=1e-14,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001176
- InterPro:   IPR004839
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR015422 [H]

Pfam domain/function: PF00155 Aminotran_1_2 [H]

EC number: 2.6.1.1

Molecular weight: Translated: 47546; Mature: 47546

Theoretical pI: Translated: 6.65; Mature: 6.65

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.4 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
3.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFCLEFTHWEIAVTADKKPRLRTIQKSTKLDNVCYDIRGPVMARARQMEEEGQRIIKLNI
CEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEC
GNPAPFGFEAPEEIVQDVILNLPNASGYSDSKGLFAARKAIMHETQRKGIAGVTIDDIIV
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEE
GNGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLGGGKPRHYLCDEGAGWLPDLDD
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEECCCCCCCCEECCCCCCCCCCHHH
IRAKITPSTRAIVIINPNNPTGALYPTELLREILEIARQHQLIVYADEIYDKVLFDGVVH
HHEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
TSIASLADDLLIVTFNGLSKNYRACGYRSGWLVVSGDKRHAKDYLEGLNMLASMRLCSNV
HHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
PGQHAIQTALGGYQSINDLVAPSGRLTRQRDLAHELLTLIPGVSCVKPKAAMYLFPRLDP
CCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCC
KLYPIHDDQKFILNLLEEERVLVVQGTGFNWPRPDHLRVVFLPHEEDLTEAIGRMSRFLD
EEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
RQRAHR
HHHCCC
>Mature Secondary Structure
MFCLEFTHWEIAVTADKKPRLRTIQKSTKLDNVCYDIRGPVMARARQMEEEGQRIIKLNI
CEEEEEECEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCCEEEEEEC
GNPAPFGFEAPEEIVQDVILNLPNASGYSDSKGLFAARKAIMHETQRKGIAGVTIDDIIV
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHEEE
GNGVSELIVMAMQALLNNGDEVLVPAPDYPLWTAAVSLGGGKPRHYLCDEGAGWLPDLDD
CCCHHHHHHHHHHHHHCCCCEEEEECCCCCHHHHEEECCCCCCCCEECCCCCCCCCCHHH
IRAKITPSTRAIVIINPNNPTGALYPTELLREILEIARQHQLIVYADEIYDKVLFDGVVH
HHEEECCCCEEEEEEECCCCCCCCCHHHHHHHHHHHHHHCCEEEEHHHHHHHHHHHHHHH
TSIASLADDLLIVTFNGLSKNYRACGYRSGWLVVSGDKRHAKDYLEGLNMLASMRLCSNV
HHHHHHHCCEEEEEECCCCCCCCCCCCCCCEEEEECCHHHHHHHHHHHHHHHHHHHHHCC
PGQHAIQTALGGYQSINDLVAPSGRLTRQRDLAHELLTLIPGVSCVKPKAAMYLFPRLDP
CCHHHHHHHHCCHHHHHHHHCCCCCCHHHHHHHHHHHHHCCCCCCCCCCHHEEEEECCCC
KLYPIHDDQKFILNLLEEERVLVVQGTGFNWPRPDHLRVVFLPHEEDLTEAIGRMSRFLD
EEEECCCCHHHHHHHHCCCCEEEEEECCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHHH
RQRAHR
HHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: L-aspartate; 2-oxoglutarate

Specific reaction: L-aspartate + 2-oxoglutarate = oxaloacetate + L-glutamate

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 12471157 [H]