Click here to switch to the map view.

The map label for this gene is surE

Identifier: 74316853

GI number: 74316853

Start: 885985

End: 886728

Strand: Direct

Name: surE

Synonym: Tbd_0835

Alternate gene names: 74316853

Gene position: 885985-886728 (Clockwise)

Preceding gene: 74316852

Following gene: 74316854

Centisome position: 30.45

GC content: 66.94

Gene sequence:

>744_bases
ATGCGCATCCTGCTTTCCAACGACGACGGTTATTTCGCCCCGGGCCTGGCGGCGCTGGCCGAGGCGCTGGCGCCACTCGC
CGAGGTCACGGTCGTCGCGCCCGAGCGCGACCGCAGCGGCGCGTCCAATTCGCTCACGCTCGATCGTCCGCTCATGCTGC
GGCAGGCCCCGAGCGGTTTCTATTACGTCAACGGTACGCCGACCGATTGCGTCCACCTCGCCGTCACCGGCATGCTCGAC
CATCTGCCCGACATGGTGATCTCGGGCATCAATCACGGCGCGAACATGGGCGACGACACGATTTATTCGGGCACGGTCGC
CGCGGCGACCGAGGGCTATCTGCTCGGCATCCCGTCGATCGCCGTCTCGCTCGCGAACCACAACGCCCTGTATTTCGACA
CGGCCGCGCGCGTCGTCAGCGACCTCGTGCGGCGTCTGCAGAACAATCCGCCGACCGAGCCGACGCTGCTCAATGTCAAC
GTTCCCGATCGCGCCTGGGATGCGGTCAGGGGGATCAGCGTGACGCGGCTCGGCAAGCGGCACAAGGCCGAGTCCGTCGT
CAAGACGTCCAATCCCCGCGGGCAGACCGTCTACTGGGTCGGCGCGGCCGGCGCCGCGCAGGACGCCGGCGAGGGCACGG
ACTTCCATGCCGTCGCCAACGGCTATGTTTCGATCACCCCGCTGCAAATGGACCTCACCCGTTTCAGCCAGATGGAAAGC
GTGACGGCGTGGCTGAAACCCTGA

Upstream 100 bases:

>100_bases
CTGGATCGCGCAAGACCCGTTGTAGAATCGGGCGCATGTTCGACGCCCGCTTTACGCCATCCCCGTCCCGATCGTCCGTT
TCGCGGGGAGGCTGCCGCTG

Downstream 100 bases:

>100_bases
ACCCGCGCGCCGGCATCGGCATGACCTCGGCGCGGACCCGCGGCCGCATGGTCGAGCGTCTGCGCGAGCAGGGCATCAAG
GACGAAATGGTGCTGGCGGC

Product: stationary phase survival protein SurE

Products: NA

Alternate protein names: Nucleoside 5'-monophosphate phosphohydrolase

Number of amino acids: Translated: 247; Mature: 247

Protein sequence:

>247_residues
MRILLSNDDGYFAPGLAALAEALAPLAEVTVVAPERDRSGASNSLTLDRPLMLRQAPSGFYYVNGTPTDCVHLAVTGMLD
HLPDMVISGINHGANMGDDTIYSGTVAAATEGYLLGIPSIAVSLANHNALYFDTAARVVSDLVRRLQNNPPTEPTLLNVN
VPDRAWDAVRGISVTRLGKRHKAESVVKTSNPRGQTVYWVGAAGAAQDAGEGTDFHAVANGYVSITPLQMDLTRFSQMES
VTAWLKP

Sequences:

>Translated_247_residues
MRILLSNDDGYFAPGLAALAEALAPLAEVTVVAPERDRSGASNSLTLDRPLMLRQAPSGFYYVNGTPTDCVHLAVTGMLD
HLPDMVISGINHGANMGDDTIYSGTVAAATEGYLLGIPSIAVSLANHNALYFDTAARVVSDLVRRLQNNPPTEPTLLNVN
VPDRAWDAVRGISVTRLGKRHKAESVVKTSNPRGQTVYWVGAAGAAQDAGEGTDFHAVANGYVSITPLQMDLTRFSQMES
VTAWLKP
>Mature_247_residues
MRILLSNDDGYFAPGLAALAEALAPLAEVTVVAPERDRSGASNSLTLDRPLMLRQAPSGFYYVNGTPTDCVHLAVTGMLD
HLPDMVISGINHGANMGDDTIYSGTVAAATEGYLLGIPSIAVSLANHNALYFDTAARVVSDLVRRLQNNPPTEPTLLNVN
VPDRAWDAVRGISVTRLGKRHKAESVVKTSNPRGQTVYWVGAAGAAQDAGEGTDFHAVANGYVSITPLQMDLTRFSQMES
VTAWLKP

Specific function: Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates

COG id: COG0496

COG function: function code R; Predicted acid phosphatase

Gene ontology:

Cell location: Cytoplasm (Potential)

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the surE nucleotidase family

Homologues:

Organism=Escherichia coli, GI1789101, Length=247, Percent_Identity=54.251012145749, Blast_Score=252, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): SURE_THIDA (Q3SKJ3)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314593.1
- ProteinModelPortal:   Q3SKJ3
- SMR:   Q3SKJ3
- STRING:   Q3SKJ3
- GeneID:   3673532
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0835
- NMPDR:   fig|292415.3.peg.221
- eggNOG:   COG0496
- HOGENOM:   HBG600532
- OMA:   NGFYYVN
- PhylomeDB:   Q3SKJ3
- ProtClustDB:   PRK00346
- BioCyc:   TDEN292415:TBD_0835-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00060
- InterPro:   IPR002828
- Gene3D:   G3DSA:3.40.1210.10
- TIGRFAMs:   TIGR00087

Pfam domain/function: PF01975 SurE; SSF64167 SurE-like_Pase/nucleotidase

EC number: =3.1.3.5

Molecular weight: Translated: 26317; Mature: 26317

Theoretical pI: Translated: 5.56; Mature: 5.56

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRILLSNDDGYFAPGLAALAEALAPLAEVTVVAPERDRSGASNSLTLDRPLMLRQAPSGF
CEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEECCCCCEEECCCCE
YYVNGTPTDCVHLAVTGMLDHLPDMVISGINHGANMGDDTIYSGTVAAATEGYLLGIPSI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCEEEECCCCEEEECHHH
AVSLANHNALYFDTAARVVSDLVRRLQNNPPTEPTLLNVNVPDRAWDAVRGISVTRLGKR
HEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHCCHHHHHCCH
HKAESVVKTSNPRGQTVYWVGAAGAAQDAGEGTDFHAVANGYVSITPLQMDLTRFSQMES
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCEEEEEEEHHHHHHHHHHHH
VTAWLKP
HHHHCCC
>Mature Secondary Structure
MRILLSNDDGYFAPGLAALAEALAPLAEVTVVAPERDRSGASNSLTLDRPLMLRQAPSGF
CEEEEECCCCCCCCCHHHHHHHHHHHHHEEEECCCCCCCCCCCCEEECCCCCEEECCCCE
YYVNGTPTDCVHLAVTGMLDHLPDMVISGINHGANMGDDTIYSGTVAAATEGYLLGIPSI
EEECCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCEECCEEEECCCCEEEECHHH
AVSLANHNALYFDTAARVVSDLVRRLQNNPPTEPTLLNVNVPDRAWDAVRGISVTRLGKR
HEECCCCCEEEEHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCHHHHHHHCCHHHHHCCH
HKAESVVKTSNPRGQTVYWVGAAGAAQDAGEGTDFHAVANGYVSITPLQMDLTRFSQMES
HHHHHHHHCCCCCCCEEEEEECCCCCCCCCCCCCEEEEECCEEEEEEEHHHHHHHHHHHH
VTAWLKP
HHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA