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The map label for this gene is yaeL [C]

Identifier: 74316810

GI number: 74316810

Start: 834357

End: 835721

Strand: Direct

Name: yaeL [C]

Synonym: Tbd_0792

Alternate gene names: 74316810

Gene position: 834357-835721 (Clockwise)

Preceding gene: 74316809

Following gene: 74316811

Centisome position: 28.67

GC content: 66.52

Gene sequence:

>1365_bases
GTGCAGCTACGCATGAATCTGCTGACGACCCTGCTGTGGTTTCTGCTCGCCATCGGTATCCTCGTTGTGGCGCACGAGCT
CGGCCATTATTTCGCGGCGCGTCTGGCCGGCGTGAAGGTGTTGCGTTTTTCGGTCGGTTTCGGCAGGCCCCTGTTCAGTC
GGCGCCTCGGGCGCGACCGCACCGAATGGACCGTATCGGCCCTGCCGTTCGGCGGCTACGTCAAGATGCTCGACGAGCGC
GAAGGCGAGGTCCCCGCTGCCGAGGCGCACCGTAGTTTCAATCGCGCAACCGTCTGGCGCCGTATCGGGATCGTCGTCGC
CGGGCCCACGGCCAATTTCCTGCTCGCCATCGTTTTCTATTGGGCGCTCTTCGTGCACGGCGTGCCGGCGATGAAGCCGC
TGATCGGCGAGCCGCCGGCGGGCACGCCCGCGGCGCACGCGGGGCTCGCCGCCGGCGACGAGATTCGCAGCGTCAACGGT
GTCGAGACGCCGTCGTTCCAGGACCTGCGCCTCAACCTGCTGCGTGCCGGCGTGGCCGGCGGTACGCTCGAGCTCGCGCT
CGCCGACGGGCGCAGCGCACGGCTCGAGGTGTCGCCGCTCGAAACCGAAAACCTCGAGCGCGACGCGCTGACGCCGCTCG
GCATCGTGCGCTACGACCCCGATATCGCGCCCGTGATCGGGGAGGTGTTGCCCGACGGTGCCGCGGCGCGCGCCGGATTC
AAGCGCTGGGACCGGCTGATCGCCGCCGACGGCGAGGCGATCGCAACCTGGCAGGGGTGGGTCGAAGTCGTGCGTGCGCA
TCCGTCCAGGCCCTTGCGCATCGATTATCAGCGCGACGGCGAACGCCGCGTGTCGACGGTGACGCCCGACGCGGTCGACG
AGGCGGGCAAGCGCGTCGGCAAGATCGGCGCAGGTCCGCATGTCGATCCCGCCGTATTCGATGCGCTGATGACCGAACTG
CATTACGGCCCGGTCGAGGCCTTGTGGCAAGGCGCCGGCAAGACCTGGGACATGACCGTGTTCACGCTCGAGATGATGGG
CCGCATGGTGCTCGGCCAGGTGTCGTGGAAGAACCTGTCCGGACCCTTGACCATCGCCGATTACGCGGGCCAGAGCGCCG
ACCTCGGATGGATCAGTTTCGTCGGTTTTCTCGCGCTCGTGAGCGTGAGTCTCGGGGTGCTGAACCTGCTGCCAATCCCG
CTGTTGGACGGTGGACACCTCATGTATTATGTCGCGGAAGTTTTTCGCGGTCGGCCGGTGTCCGAGCGCGCCATGGAAAT
AGGGAGCCGGATCGGCATGGCGCTTCTGCTGTTGCTGATGTCGTTCGCCCTCTTCAACGATTTGCAACGTCTAATAAGCG
GATGA

Upstream 100 bases:

>100_bases
CCCACGCCCTCGATGCGGTGGCCGGGGGGCGCGCCGACACGCTCGACGAGCTGCTCGACGCCGACCACCGGGCGCGTCGC
GTCGCCGACGACTATCTCAG

Downstream 100 bases:

>100_bases
AAAAACCCATGACCCTGACCCGTCTGACGCTGGCCCTCGCTGCGGTATTCGTCACGCATGCCGCATCCGCCGAGGCGCCT
TTCGTCGTCAAGGACATCCG

Product: peptidase M50 membrane-associated zinc metallopeptidase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 454; Mature: 454

Protein sequence:

>454_residues
MQLRMNLLTTLLWFLLAIGILVVAHELGHYFAARLAGVKVLRFSVGFGRPLFSRRLGRDRTEWTVSALPFGGYVKMLDER
EGEVPAAEAHRSFNRATVWRRIGIVVAGPTANFLLAIVFYWALFVHGVPAMKPLIGEPPAGTPAAHAGLAAGDEIRSVNG
VETPSFQDLRLNLLRAGVAGGTLELALADGRSARLEVSPLETENLERDALTPLGIVRYDPDIAPVIGEVLPDGAAARAGF
KRWDRLIAADGEAIATWQGWVEVVRAHPSRPLRIDYQRDGERRVSTVTPDAVDEAGKRVGKIGAGPHVDPAVFDALMTEL
HYGPVEALWQGAGKTWDMTVFTLEMMGRMVLGQVSWKNLSGPLTIADYAGQSADLGWISFVGFLALVSVSLGVLNLLPIP
LLDGGHLMYYVAEVFRGRPVSERAMEIGSRIGMALLLLLMSFALFNDLQRLISG

Sequences:

>Translated_454_residues
MQLRMNLLTTLLWFLLAIGILVVAHELGHYFAARLAGVKVLRFSVGFGRPLFSRRLGRDRTEWTVSALPFGGYVKMLDER
EGEVPAAEAHRSFNRATVWRRIGIVVAGPTANFLLAIVFYWALFVHGVPAMKPLIGEPPAGTPAAHAGLAAGDEIRSVNG
VETPSFQDLRLNLLRAGVAGGTLELALADGRSARLEVSPLETENLERDALTPLGIVRYDPDIAPVIGEVLPDGAAARAGF
KRWDRLIAADGEAIATWQGWVEVVRAHPSRPLRIDYQRDGERRVSTVTPDAVDEAGKRVGKIGAGPHVDPAVFDALMTEL
HYGPVEALWQGAGKTWDMTVFTLEMMGRMVLGQVSWKNLSGPLTIADYAGQSADLGWISFVGFLALVSVSLGVLNLLPIP
LLDGGHLMYYVAEVFRGRPVSERAMEIGSRIGMALLLLLMSFALFNDLQRLISG
>Mature_454_residues
MQLRMNLLTTLLWFLLAIGILVVAHELGHYFAARLAGVKVLRFSVGFGRPLFSRRLGRDRTEWTVSALPFGGYVKMLDER
EGEVPAAEAHRSFNRATVWRRIGIVVAGPTANFLLAIVFYWALFVHGVPAMKPLIGEPPAGTPAAHAGLAAGDEIRSVNG
VETPSFQDLRLNLLRAGVAGGTLELALADGRSARLEVSPLETENLERDALTPLGIVRYDPDIAPVIGEVLPDGAAARAGF
KRWDRLIAADGEAIATWQGWVEVVRAHPSRPLRIDYQRDGERRVSTVTPDAVDEAGKRVGKIGAGPHVDPAVFDALMTEL
HYGPVEALWQGAGKTWDMTVFTLEMMGRMVLGQVSWKNLSGPLTIADYAGQSADLGWISFVGFLALVSVSLGVLNLLPIP
LLDGGHLMYYVAEVFRGRPVSERAMEIGSRIGMALLLLLMSFALFNDLQRLISG

Specific function: Unknown

COG id: COG0750

COG function: function code M; Predicted membrane-associated Zn-dependent proteases 1

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PDZ (DHR) domain [H]

Homologues:

Organism=Escherichia coli, GI1786373, Length=451, Percent_Identity=40.3547671840355, Blast_Score=329, Evalue=2e-91,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001478
- InterPro:   IPR004387
- InterPro:   IPR008915 [H]

Pfam domain/function: PF00595 PDZ; PF02163 Peptidase_M50 [H]

EC number: NA

Molecular weight: Translated: 49374; Mature: 49374

Theoretical pI: Translated: 6.81; Mature: 6.81

Prosite motif: PS00142 ZINC_PROTEASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQLRMNLLTTLLWFLLAIGILVVAHELGHYFAARLAGVKVLRFSVGFGRPLFSRRLGRDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCC
TEWTVSALPFGGYVKMLDEREGEVPAAEAHRSFNRATVWRRIGIVVAGPTANFLLAIVFY
CCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHH
WALFVHGVPAMKPLIGEPPAGTPAAHAGLAAGDEIRSVNGVETPSFQDLRLNLLRAGVAG
HHHHHCCCCHHHCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCC
GTLELALADGRSARLEVSPLETENLERDALTPLGIVRYDPDIAPVIGEVLPDGAAARAGF
CEEEEEEECCCCCEEEECCCCCCCCCHHCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHH
KRWDRLIAADGEAIATWQGWVEVVRAHPSRPLRIDYQRDGERRVSTVTPDAVDEAGKRVG
HHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHH
KIGAGPHVDPAVFDALMTELHYGPVEALWQGAGKTWDMTVFTLEMMGRMVLGQVSWKNLS
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
GPLTIADYAGQSADLGWISFVGFLALVSVSLGVLNLLPIPLLDGGHLMYYVAEVFRGRPV
CCEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
SERAMEIGSRIGMALLLLLMSFALFNDLQRLISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MQLRMNLLTTLLWFLLAIGILVVAHELGHYFAARLAGVKVLRFSVGFGRPLFSRRLGRDR
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEEEECCCCCHHHHHHHCCCC
TEWTVSALPFGGYVKMLDEREGEVPAAEAHRSFNRATVWRRIGIVVAGPTANFLLAIVFY
CCEEEEECCCCHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHCCEEEECCHHHHHHHHHHH
WALFVHGVPAMKPLIGEPPAGTPAAHAGLAAGDEIRSVNGVETPSFQDLRLNLLRAGVAG
HHHHHCCCCHHHCCCCCCCCCCCHHHCCCCCCCHHHCCCCCCCCCHHHHHHHHHHHCCCC
GTLELALADGRSARLEVSPLETENLERDALTPLGIVRYDPDIAPVIGEVLPDGAAARAGF
CEEEEEEECCCCCEEEECCCCCCCCCHHCCCCCCEEEECCCHHHHHHHHCCCCHHHHHHH
KRWDRLIAADGEAIATWQGWVEVVRAHPSRPLRIDYQRDGERRVSTVTPDAVDEAGKRVG
HHHHHHHHCCCCEEHHHHHHHHHHHHCCCCCEEEEECCCCCCEECCCCCHHHHHHHHHHH
KIGAGPHVDPAVFDALMTELHYGPVEALWQGAGKTWDMTVFTLEMMGRMVLGQVSWKNLS
CCCCCCCCCHHHHHHHHHHHCCCCHHHHHHCCCCCEEHHHHHHHHHHHHHHHHCCCCCCC
GPLTIADYAGQSADLGWISFVGFLALVSVSLGVLNLLPIPLLDGGHLMYYVAEVFRGRPV
CCEEEHHCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCHHHHHHHHHHCCCCC
SERAMEIGSRIGMALLLLLMSFALFNDLQRLISG
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]