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The map label for this gene is cdsA [H]

Identifier: 74316808

GI number: 74316808

Start: 832385

End: 833191

Strand: Direct

Name: cdsA [H]

Synonym: Tbd_0790

Alternate gene names: 74316808

Gene position: 832385-833191 (Clockwise)

Preceding gene: 74316807

Following gene: 74316809

Centisome position: 28.61

GC content: 70.63

Gene sequence:

>807_bases
ATGACACCCCTGGCACGACGCGTGTCCACGGCGCTGCTGTTGCTGGCCGTATTCGTACCGGCCGCCCTGTGGGCGCCGGC
CTGGCTGTGGGCGCTCTTGATGGCCGTCGTGGTCGGCGCGGCCGCCTACGAGTGGGCGCGCATCAGCCAATTCCCCGGTC
CGATGGCCGGTTTTTACGCGGGCGCGCTCGCCCTCGTCGCCGCCGCCTTGCCCTACGTGCTCGGTAACGGCTGGCCGGCT
TTCCAGGGCGGACTCTTCGCCCTCGCCGCTGCCTTCTGGCTCGTCGTCGCGCCGCTGTGGCTGCTCGGAAGCTGGCGTGC
ATCGGCCGCGTTCGTGCGCGCCGCGGTCGGCGTCGTCCTGCTCGTCCCCACCGGGGCCGCGCTGCTCTACCTGCAGGCGC
GCGGCCCCGCCGTTTTGCTCGGCGTGATCGCGATCGTGTGGATCGCCGACACGGCCGCGTATTTTTTCGGCCGTCGCTTC
GGCCGTCACAAGCTGGCGCCGCGCATCAGTCCCGGCAAAACCTGGGAGGGCGCGATCGGCGCGCTGGCGGCCGTCGTCGT
CTACGCGGCGGCATTGAGCGTGGCGGTCGGCATGCCGCTCGTGTCGCTCGTCATCATGGCGGCCGGCCTGCTTTATGTGT
CGGTGCTGGGTGACCTGTTCGAATCGTGGATCAAGCGCGTCGCCGGCATGAAGGACAGCGGCAACCTGCTGCCCGGTCAC
GGCGGCGTGCTCGACCGCATCGATGCGCTGACCTCGACGCTGCCCGTCGCTGCGGGACTCCTGATGTGGCTGGAGCACGG
CGCGTGA

Upstream 100 bases:

>100_bases
CTCGACGCCGCGATCGCTTCGTATCGCACGCGCGAACGTCGATTCGGTCGCACCAGCGAACAGCTGCTGACGGCGTCGTG
ACCGCACATCGAGGATTGCC

Downstream 100 bases:

>100_bases
GGCGCCGCGTTCTCACCGTCCTTGGCGCGACCGGGACGATAGGCGTCAATACGCTCGACGTCGTTTCACGCCACCCCGAA
CGCTTCGAGATCTTCGCGCT

Product: phosphatidate cytidylyltransferase

Products: NA

Alternate protein names: CDP-DAG synthase; CDP-DG synthase; CDP-diacylglycerol synthase; CDS; CDP-diglyceride pyrophosphorylase; CDP-diglyceride synthase; CTP:phosphatidate cytidylyltransferase [H]

Number of amino acids: Translated: 268; Mature: 267

Protein sequence:

>268_residues
MTPLARRVSTALLLLAVFVPAALWAPAWLWALLMAVVVGAAAYEWARISQFPGPMAGFYAGALALVAAALPYVLGNGWPA
FQGGLFALAAAFWLVVAPLWLLGSWRASAAFVRAAVGVVLLVPTGAALLYLQARGPAVLLGVIAIVWIADTAAYFFGRRF
GRHKLAPRISPGKTWEGAIGALAAVVVYAAALSVAVGMPLVSLVIMAAGLLYVSVLGDLFESWIKRVAGMKDSGNLLPGH
GGVLDRIDALTSTLPVAAGLLMWLEHGA

Sequences:

>Translated_268_residues
MTPLARRVSTALLLLAVFVPAALWAPAWLWALLMAVVVGAAAYEWARISQFPGPMAGFYAGALALVAAALPYVLGNGWPA
FQGGLFALAAAFWLVVAPLWLLGSWRASAAFVRAAVGVVLLVPTGAALLYLQARGPAVLLGVIAIVWIADTAAYFFGRRF
GRHKLAPRISPGKTWEGAIGALAAVVVYAAALSVAVGMPLVSLVIMAAGLLYVSVLGDLFESWIKRVAGMKDSGNLLPGH
GGVLDRIDALTSTLPVAAGLLMWLEHGA
>Mature_267_residues
TPLARRVSTALLLLAVFVPAALWAPAWLWALLMAVVVGAAAYEWARISQFPGPMAGFYAGALALVAAALPYVLGNGWPAF
QGGLFALAAAFWLVVAPLWLLGSWRASAAFVRAAVGVVLLVPTGAALLYLQARGPAVLLGVIAIVWIADTAAYFFGRRFG
RHKLAPRISPGKTWEGAIGALAAVVVYAAALSVAVGMPLVSLVIMAAGLLYVSVLGDLFESWIKRVAGMKDSGNLLPGHG
GVLDRIDALTSTLPVAAGLLMWLEHGA

Specific function: Phospholipid biosynthesis. [C]

COG id: COG0575

COG function: function code I; CDP-diglyceride synthetase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDS family [H]

Homologues:

Organism=Escherichia coli, GI87081696, Length=282, Percent_Identity=38.2978723404255, Blast_Score=135, Evalue=3e-33,
Organism=Escherichia coli, GI1787677, Length=109, Percent_Identity=46.7889908256881, Blast_Score=91, Evalue=8e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000374 [H]

Pfam domain/function: PF01148 CTP_transf_1 [H]

EC number: =2.7.7.41 [H]

Molecular weight: Translated: 27923; Mature: 27791

Theoretical pI: Translated: 10.42; Mature: 10.42

Prosite motif: PS01315 CDS

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPLARRVSTALLLLAVFVPAALWAPAWLWALLMAVVVGAAAYEWARISQFPGPMAGFYA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GALALVAAALPYVLGNGWPAFQGGLFALAAAFWLVVAPLWLLGSWRASAAFVRAAVGVVL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVPTGAALLYLQARGPAVLLGVIAIVWIADTAAYFFGRRFGRHKLAPRISPGKTWEGAIG
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHH
ALAAVVVYAAALSVAVGMPLVSLVIMAAGLLYVSVLGDLFESWIKRVAGMKDSGNLLPGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGVLDRIDALTSTLPVAAGLLMWLEHGA
CCHHHHHHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure 
TPLARRVSTALLLLAVFVPAALWAPAWLWALLMAVVVGAAAYEWARISQFPGPMAGFYA
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
GALALVAAALPYVLGNGWPAFQGGLFALAAAFWLVVAPLWLLGSWRASAAFVRAAVGVVL
HHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
LVPTGAALLYLQARGPAVLLGVIAIVWIADTAAYFFGRRFGRHKLAPRISPGKTWEGAIG
EECCCCEEEEEECCCHHHHHHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCCCCCHHHHH
ALAAVVVYAAALSVAVGMPLVSLVIMAAGLLYVSVLGDLFESWIKRVAGMKDSGNLLPGH
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCC
GGVLDRIDALTSTLPVAAGLLMWLEHGA
CCHHHHHHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]