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The map label for this gene is frr

Identifier: 74316806

GI number: 74316806

Start: 831039

End: 831608

Strand: Direct

Name: frr

Synonym: Tbd_0788

Alternate gene names: 74316806

Gene position: 831039-831608 (Clockwise)

Preceding gene: 74316805

Following gene: 74316807

Centisome position: 28.56

GC content: 63.33

Gene sequence:

>570_bases
ATGGCTGAAACCACGATCACCGACATCAAGCAGTCCGCCGAGCAGAAGATGGGCAAGACGCTCGAGGCGCTGAAAAACGA
TCTCGCGAAGGTGCGCACCGGACGTGCGCACGCCGGCATTCTCGACCACGTCCTCGTCGACTATTACGGCAACCCGACGC
CGGTGCCCCAGGTCGCCAACGTCTCGCTGGTGGATTCGCGCACGCTCGGCGTGCAGCCCTACGAAAAGAACATGGTCGGC
AAGATCGAAAAGGCGATCCGCGACGGCGATCTCGGTCTCAACCCGGCGACGCACGGCGACGTCATCCGCGTGCCGATGCC
GGCGCTGACCGAGGAGCGGCGCCGCGACCTGATCAAGGTCGTGCGCAACGAAGCCGAGGGCGCGCGCGTCGCCGTCCGCA
ACATCCGCCGCGATGCCAACGCCTCGCTCAAGGATATGGTCAAGGCCAAGACCGCGACCGAGGACGAGGAGCGTCGTACC
CAAGACGAAGTGCAGAAGCTGACCGACAAATTCATCGGCGAAATCGACAAAATGCTCGCCGAAAAAGAGAAGGACCTGCT
CGCGGTCTGA

Upstream 100 bases:

>100_bases
GTCCCTGGTCGTGTTCAACGTCTTCAAACCCGGCGCGCTCAAGCGCGTGGTGATGGGCGAGGACGAGGGCACGCGGGTCA
GCAACCATTGAGGAATTGAA

Downstream 100 bases:

>100_bases
GCGGCCCGAGTCCGTCGGCGTGTCTACCCGCACCAAGCAGGCGATCCCCGTGACCTCGGACGTGCCGCGGCACATTGCCA
TCATCATGGACGGCAACGGG

Product: ribosome recycling factor

Products: NA

Alternate protein names: RRF; Ribosome-releasing factor

Number of amino acids: Translated: 189; Mature: 188

Protein sequence:

>189_residues
MAETTITDIKQSAEQKMGKTLEALKNDLAKVRTGRAHAGILDHVLVDYYGNPTPVPQVANVSLVDSRTLGVQPYEKNMVG
KIEKAIRDGDLGLNPATHGDVIRVPMPALTEERRRDLIKVVRNEAEGARVAVRNIRRDANASLKDMVKAKTATEDEERRT
QDEVQKLTDKFIGEIDKMLAEKEKDLLAV

Sequences:

>Translated_189_residues
MAETTITDIKQSAEQKMGKTLEALKNDLAKVRTGRAHAGILDHVLVDYYGNPTPVPQVANVSLVDSRTLGVQPYEKNMVG
KIEKAIRDGDLGLNPATHGDVIRVPMPALTEERRRDLIKVVRNEAEGARVAVRNIRRDANASLKDMVKAKTATEDEERRT
QDEVQKLTDKFIGEIDKMLAEKEKDLLAV
>Mature_188_residues
AETTITDIKQSAEQKMGKTLEALKNDLAKVRTGRAHAGILDHVLVDYYGNPTPVPQVANVSLVDSRTLGVQPYEKNMVGK
IEKAIRDGDLGLNPATHGDVIRVPMPALTEERRRDLIKVVRNEAEGARVAVRNIRRDANASLKDMVKAKTATEDEERRTQ
DEVQKLTDKFIGEIDKMLAEKEKDLLAV

Specific function: Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another

COG id: COG0233

COG function: function code J; Ribosome recycling factor

Gene ontology:

Cell location: Cytoplasm

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RRF family

Homologues:

Organism=Homo sapiens, GI20270317, Length=176, Percent_Identity=30.1136363636364, Blast_Score=79, Evalue=3e-15,
Organism=Homo sapiens, GI291042689, Length=105, Percent_Identity=36.1904761904762, Blast_Score=69, Evalue=3e-12,
Organism=Escherichia coli, GI1786368, Length=182, Percent_Identity=53.8461538461538, Blast_Score=202, Evalue=1e-53,
Organism=Drosophila melanogaster, GI24661488, Length=179, Percent_Identity=27.9329608938547, Blast_Score=72, Evalue=3e-13,

Paralogues:

None

Copy number: 840 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): RRF_THIDA (Q3SKN6)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314546.1
- ProteinModelPortal:   Q3SKN6
- SMR:   Q3SKN6
- STRING:   Q3SKN6
- GeneID:   3673485
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0788
- NMPDR:   fig|292415.3.peg.52
- eggNOG:   COG0233
- HOGENOM:   HBG533975
- OMA:   YYGAETP
- PhylomeDB:   Q3SKN6
- BioCyc:   TDEN292415:TBD_0788-MONOMER
- GO:   GO:0005737
- HAMAP:   MF_00040
- InterPro:   IPR002661
- InterPro:   IPR015998
- PANTHER:   PTHR20982
- PANTHER:   PTHR20982:SF3
- TIGRFAMs:   TIGR00496

Pfam domain/function: PF01765 RRF; SSF55194 Ribosome_recyc_fac

EC number: NA

Molecular weight: Translated: 21011; Mature: 20880

Theoretical pI: Translated: 7.77; Mature: 7.77

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.7 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAETTITDIKQSAEQKMGKTLEALKNDLAKVRTGRAHAGILDHVLVDYYGNPTPVPQVAN
CCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VSLVDSRTLGVQPYEKNMVGKIEKAIRDGDLGLNPATHGDVIRVPMPALTEERRRDLIKV
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
VRNEAEGARVAVRNIRRDANASLKDMVKAKTATEDEERRTQDEVQKLTDKFIGEIDKMLA
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEKDLLAV
HHHHHHCCC
>Mature Secondary Structure 
AETTITDIKQSAEQKMGKTLEALKNDLAKVRTGRAHAGILDHVLVDYYGNPTPVPQVAN
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHCCCCCCCCCCCC
VSLVDSRTLGVQPYEKNMVGKIEKAIRDGDLGLNPATHGDVIRVPMPALTEERRRDLIKV
EEEECCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEECCCHHHHHHHHHHHHHH
VRNEAEGARVAVRNIRRDANASLKDMVKAKTATEDEERRTQDEVQKLTDKFIGEIDKMLA
HHCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
EKEKDLLAV
HHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA