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The map label for this gene is pgsA [H]

Identifier: 74316718

GI number: 74316718

Start: 741440

End: 742006

Strand: Reverse

Name: pgsA [H]

Synonym: Tbd_0700

Alternate gene names: 74316718

Gene position: 742006-741440 (Counterclockwise)

Preceding gene: 74316719

Following gene: 74316717

Centisome position: 25.5

GC content: 66.14

Gene sequence:

>567_bases
ATGCCGCTCAATCTCCCGAACCTGCTGACCTGGCTGCGCATCCTGTTCATTCCGCTCATGGCGGGGGTGTTCTATCTTCC
CGACGGCTGGGTCACGCCGCCCCAGGCGAACCTGCTCGCCGCGCTCTTTTTCGGCGTCGCCGCGCTGACCGACTGGCTCG
ACGGGTACCTTGCGCGCGCGCTCGGCCAGACCTCCGCGTTCGGCGCGTTTCTCGATCCGGTCGCCGACAAGCTCATGGTC
GCCGCGGCGCTGATCGTGCTGATCGATCTCGACCGCGTCGCGCCGCTGATCGGCCTCATCATCATCGGCCGTGAGATCAC
GATCTCGGCGTTGCGCGAATGGATGGCCAAGGCGGGCAAGTCGGCGAGCGTCGCGGTCTCCTTCGTCGGCAAGCTGAAGA
CCGCAGGGCAGATGGTCGCCATCGTCCTGCTGCTCTACTTCGCGCCGCTGGCCGGCCTGCCCACGGCCCGGATCGGGACC
CTGCTGATCTGGCTGGCCGCCGTCCTCACGTTGATTTCGATGGCCTACTACCTAATGATGGCGGCGCGGGCGCTGCAAAA
AACTTGA

Upstream 100 bases:

>100_bases
CTGCAGGGCGTGCGCAACGCGGGCGTGGACGCCCTTGCCTCGGTCAACGGTATCAGCCGAGAATTGGCGGAAATCATCTA
TAACGCGCTCCATTGACCCG

Downstream 100 bases:

>100_bases
GGAAAATCCGCGCCGGCTGTTGACAGAAAATGACGGAATCACCATAATGCGCAGCCTTCAACGCGGGAATAGCTCAGCTG
GTAGAGCGCAACCTTGCCAA

Product: CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase

Products: NA

Alternate protein names: Phosphatidylglycerophosphate synthase; PGP synthase [H]

Number of amino acids: Translated: 188; Mature: 187

Protein sequence:

>188_residues
MPLNLPNLLTWLRILFIPLMAGVFYLPDGWVTPPQANLLAALFFGVAALTDWLDGYLARALGQTSAFGAFLDPVADKLMV
AAALIVLIDLDRVAPLIGLIIIGREITISALREWMAKAGKSASVAVSFVGKLKTAGQMVAIVLLLYFAPLAGLPTARIGT
LLIWLAAVLTLISMAYYLMMAARALQKT

Sequences:

>Translated_188_residues
MPLNLPNLLTWLRILFIPLMAGVFYLPDGWVTPPQANLLAALFFGVAALTDWLDGYLARALGQTSAFGAFLDPVADKLMV
AAALIVLIDLDRVAPLIGLIIIGREITISALREWMAKAGKSASVAVSFVGKLKTAGQMVAIVLLLYFAPLAGLPTARIGT
LLIWLAAVLTLISMAYYLMMAARALQKT
>Mature_187_residues
PLNLPNLLTWLRILFIPLMAGVFYLPDGWVTPPQANLLAALFFGVAALTDWLDGYLARALGQTSAFGAFLDPVADKLMVA
AALIVLIDLDRVAPLIGLIIIGREITISALREWMAKAGKSASVAVSFVGKLKTAGQMVAIVLLLYFAPLAGLPTARIGTL
LIWLAAVLTLISMAYYLMMAARALQKT

Specific function: This protein catalyzes the committed step to the synthesis of the acidic phospholipids [H]

COG id: COG0558

COG function: function code I; Phosphatidylglycerophosphate synthase

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the CDP-alcohol phosphatidyltransferase class-I family [H]

Homologues:

Organism=Escherichia coli, GI1788220, Length=186, Percent_Identity=50.5376344086022, Blast_Score=149, Evalue=1e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000462
- InterPro:   IPR004570 [H]

Pfam domain/function: PF01066 CDP-OH_P_transf [H]

EC number: =2.7.8.5 [H]

Molecular weight: Translated: 20170; Mature: 20039

Theoretical pI: Translated: 10.00; Mature: 10.00

Prosite motif: PS00379 CDP_ALCOHOL_P_TRANSF

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
4.3 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
3.7 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPLNLPNLLTWLRILFIPLMAGVFYLPDGWVTPPQANLLAALFFGVAALTDWLDGYLARA
CCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQTSAFGAFLDPVADKLMVAAALIVLIDLDRVAPLIGLIIIGREITISALREWMAKAGK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SASVAVSFVGKLKTAGQMVAIVLLLYFAPLAGLPTARIGTLLIWLAAVLTLISMAYYLMM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AARALQKT
HHHHHHCC
>Mature Secondary Structure 
PLNLPNLLTWLRILFIPLMAGVFYLPDGWVTPPQANLLAALFFGVAALTDWLDGYLARA
CCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
LGQTSAFGAFLDPVADKLMVAAALIVLIDLDRVAPLIGLIIIGREITISALREWMAKAGK
HCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHCCC
SASVAVSFVGKLKTAGQMVAIVLLLYFAPLAGLPTARIGTLLIWLAAVLTLISMAYYLMM
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHH
AARALQKT
HHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]