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The map label for this gene is hflC [H]

Identifier: 74316622

GI number: 74316622

Start: 632722

End: 633603

Strand: Direct

Name: hflC [H]

Synonym: Tbd_0604

Alternate gene names: 74316622

Gene position: 632722-633603 (Clockwise)

Preceding gene: 74316621

Following gene: 74316623

Centisome position: 21.74

GC content: 60.77

Gene sequence:

>882_bases
ATGAGCAGGAATATTGGTACGCTGCTGATCGCGCTGGTCGTGGCGCTGGTGATCCTGAGCGGAAGCATGTACACGGTCGA
CCAGCGGCAGAACGCGCTGGTGTTCCAACTCGGTGAAGTGGTGGCGGTGAAGAAGACGCCGGGCCTTTATTTCAAGCTGC
CGCTCGTGCAGAACGTGCGCTATTTCGATACGCGCATCCTCACGCTCGACTCGGCCGATCCCGAACGTTTCATTACCTCG
GAAAAGAAAAACGTCCTCGTCGATTCGTTCATCAAATGGCGCGTCTTCGATGCCAAGCAGTTTTACGTGTCGGTCGGCGG
CGACGAGATGCGGGCGCAGATCCGGCTTAATCAGACGGTCAACGACGGGCTGCGCGCCGAGTTCGGCAAACGCACGGTCA
ACGAGGTCGTTTCGGGACGCCGCGAGGAGATCATGAGCATCATCCGCGCCAAGGCCGATACCGACGCGCGCAAGATCGGC
GTGCAGGTGGTCGACGTCCGCATCAAGCGCGTCGACCTGCCCGAAAGCGTTTCGGAAAACGTCTATCGGCGGATGGAAGC
CGAGCGCAAGCAGGTCGCCAACGAACTGCGTTCGACCGGTGCGGCCGAAGCCGAAAAGATCAAGGCCGACGCCGACAAGC
AGAAAGACGTGATCGTCGCCGAAGCGTATCGGGACGCGCAGCGAGTGAAGGGTGAAGGTGACGCCAGAGCGGCCTCGGTG
TACGCCGCGGCCTATGGCAGGAACCCCGAGTTCTATGCGTTCTACCGCAGCATGCAGGCCTATCGCGACAGCTTCAAGAA
CAAGAGCGACGTACTGGTGCTCGATCCCAGCGCCGACTTCTTCAAGTACATGAAGAACCCGCGGGCGTCCGGCGCGCAGT
GA

Upstream 100 bases:

>100_bases
GTGCGCTGCCCGAAGCCTTGGGATCGCCGACCGCGGCGCCGCCCGCGGCGGCTGCGCGTACGCGCGACAGCCTGGGCGGA
CGTGACCGGGAGGAGCGGCC

Downstream 100 bases:

>100_bases
GCGGCATCGACTGGCTGGCGGCTGCCGGGCTGTTGCTTCTGCTCGAAGGTCTCCTGCCGTTCGCCGCGCCGGCGCTCTGG
CGCGAGGGTTTCAGCAGGAT

Product: hypothetical protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 293; Mature: 292

Protein sequence:

>293_residues
MSRNIGTLLIALVVALVILSGSMYTVDQRQNALVFQLGEVVAVKKTPGLYFKLPLVQNVRYFDTRILTLDSADPERFITS
EKKNVLVDSFIKWRVFDAKQFYVSVGGDEMRAQIRLNQTVNDGLRAEFGKRTVNEVVSGRREEIMSIIRAKADTDARKIG
VQVVDVRIKRVDLPESVSENVYRRMEAERKQVANELRSTGAAEAEKIKADADKQKDVIVAEAYRDAQRVKGEGDARAASV
YAAAYGRNPEFYAFYRSMQAYRDSFKNKSDVLVLDPSADFFKYMKNPRASGAQ

Sequences:

>Translated_293_residues
MSRNIGTLLIALVVALVILSGSMYTVDQRQNALVFQLGEVVAVKKTPGLYFKLPLVQNVRYFDTRILTLDSADPERFITS
EKKNVLVDSFIKWRVFDAKQFYVSVGGDEMRAQIRLNQTVNDGLRAEFGKRTVNEVVSGRREEIMSIIRAKADTDARKIG
VQVVDVRIKRVDLPESVSENVYRRMEAERKQVANELRSTGAAEAEKIKADADKQKDVIVAEAYRDAQRVKGEGDARAASV
YAAAYGRNPEFYAFYRSMQAYRDSFKNKSDVLVLDPSADFFKYMKNPRASGAQ
>Mature_292_residues
SRNIGTLLIALVVALVILSGSMYTVDQRQNALVFQLGEVVAVKKTPGLYFKLPLVQNVRYFDTRILTLDSADPERFITSE
KKNVLVDSFIKWRVFDAKQFYVSVGGDEMRAQIRLNQTVNDGLRAEFGKRTVNEVVSGRREEIMSIIRAKADTDARKIGV
QVVDVRIKRVDLPESVSENVYRRMEAERKQVANELRSTGAAEAEKIKADADKQKDVIVAEAYRDAQRVKGEGDARAASVY
AAAYGRNPEFYAFYRSMQAYRDSFKNKSDVLVLDPSADFFKYMKNPRASGAQ

Specific function: HflC and HflK could encode or regulate a protease [H]

COG id: COG0330

COG function: function code O; Membrane protease subunits, stomatin/prohibitin homologs

Gene ontology:

Cell location: Membrane; Single-pass membrane protein (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the band 7/mec-2 family. HflC subfamily [H]

Homologues:

Organism=Escherichia coli, GI1790617, Length=315, Percent_Identity=35.8730158730159, Blast_Score=209, Evalue=2e-55,
Organism=Escherichia coli, GI1786697, Length=236, Percent_Identity=27.5423728813559, Blast_Score=62, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001107
- InterPro:   IPR010200
- InterPro:   IPR001972 [H]

Pfam domain/function: PF01145 Band_7 [H]

EC number: 3.4.-.-

Molecular weight: Translated: 33073; Mature: 32942

Theoretical pI: Translated: 9.98; Mature: 9.98

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
2.4 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
2.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSRNIGTLLIALVVALVILSGSMYTVDQRQNALVFQLGEVVAVKKTPGLYFKLPLVQNVR
CCCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCEEEEECCCCEEEECHHHHCCE
YFDTRILTLDSADPERFITSEKKNVLVDSFIKWRVFDAKQFYVSVGGDEMRAQIRLNQTV
ECCEEEEEECCCCHHHHHHCCCCHHHHHHHHHEEEEECEEEEEEECCHHEEEEEEECCCC
NDGLRAEFGKRTVNEVVSGRREEIMSIIRAKADTDARKIGVQVVDVRIKRVDLPESVSEN
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCEEEEEEEEEECCCCHHHHHH
VYRRMEAERKQVANELRSTGAAEAEKIKADADKQKDVIVAEAYRDAQRVKGEGDARAASV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHH
YAAAYGRNPEFYAFYRSMQAYRDSFKNKSDVLVLDPSADFFKYMKNPRASGAQ
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCC
>Mature Secondary Structure 
SRNIGTLLIALVVALVILSGSMYTVDQRQNALVFQLGEVVAVKKTPGLYFKLPLVQNVR
CCCHHHHHHHHHHHHHHHCCCEEEECCCCCEEEEECCCEEEEECCCCEEEECHHHHCCE
YFDTRILTLDSADPERFITSEKKNVLVDSFIKWRVFDAKQFYVSVGGDEMRAQIRLNQTV
ECCEEEEEECCCCHHHHHHCCCCHHHHHHHHHEEEEECEEEEEEECCHHEEEEEEECCCC
NDGLRAEFGKRTVNEVVSGRREEIMSIIRAKADTDARKIGVQVVDVRIKRVDLPESVSEN
CCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHCEEEEEEEEEECCCCHHHHHH
VYRRMEAERKQVANELRSTGAAEAEKIKADADKQKDVIVAEAYRDAQRVKGEGDARAASV
HHHHHHHHHHHHHHHHHHCCCHHHHHHHCCCCCCCCEEEHHHHHHHHHHCCCCCCHHHHH
YAAAYGRNPEFYAFYRSMQAYRDSFKNKSDVLVLDPSADFFKYMKNPRASGAQ
HHHHHCCCCCHHHHHHHHHHHHHHHCCCCCEEEECCCHHHHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: Hydrolase; Acting on peptide bonds (Peptidases) [C]

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: 12620739 [H]