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The map label for this gene is hflX [H]

Identifier: 74316620

GI number: 74316620

Start: 630362

End: 631531

Strand: Direct

Name: hflX [H]

Synonym: Tbd_0602

Alternate gene names: 74316620

Gene position: 630362-631531 (Clockwise)

Preceding gene: 74316619

Following gene: 74316621

Centisome position: 21.66

GC content: 66.15

Gene sequence:

>1170_bases
TTGTTTGATCGACACCAGGGTGGGGAGCGCGTCGTTCTCGCCGCGCTCGACCTGGGTGACCCCGATTTCGCCGAGAGCAT
GGCCGAACTGCGGCTGCTGGCGCGCGGCGCGGGCCTCGACATTCGCGGGGAAGTCCAGGGCAGACGCAGCCGCCCCGACG
CGGCTCTCTTCGTCGGGAGTGGTAAGGCCGACGAAATTGCGGCGCTGGTCGCCGCGACCGATGCCGAAGTCGTGATCTTC
AACCACGAACTCTCACCGGCGCAGGAACGCAACCTAGAACGCCGGCTGCATTGCCGCGTCATCGACCGGGTCAGCCTGAT
TCTCGATATCTTCGCGCGGCGCGCACGCAGCGCTGAGGGCAAGCTGCAGGTCGAACTGGCCCAGTTGCAGCATCTGTCGA
CGCGTCTCGTGCGCGGCTGGACCCACCTCGAACGCCAGCGCGGCGGCGTCGGGATGCGCGGACCCGGCGAAAAGCAATTG
GAGACCGACCGCCGCCTGATCGGAATCCGCGTCAAGGCCTTGCGCGAACGGCTCGCCAAACTCGGCAAGCAGCGGCGGAC
CCAGCGTCGGTCGCGCAGTCGCCACCGCGTGCTGTCGGTCGCGCTGGTCGGCTATACCAATGCTGGCAAATCCACGCTGT
TCAACGCCTTGACGCGCGCCGGCACCTACGCTGCCGACCAGCTGTTCGCCACGCTCGACACCACGACGCGGAAGATTTTC
CTCCCGCGCCTGGCCGATGCCGACGAGCCGGGGAGCGGAGAAGTCGTGCTGTCCGATACCGTGGGCTTCATCACCCGTCT
GCCGCACGATCTCGTCGCGGCCTTTCGCGCGACCCTCGAAGCGACGGCCGAAGCCGACCTTCTGCTGCACGTGATCGATG
CCTCGAGTCCGGTCCGCGAGCGCCAGATCGAGGCGGTCGATCAGGTGTTGCGCGAGATCGGCGCCGACGCCGTGCCACAG
CTCAGGGTCTACAACAAACTCGATCTGACGGCCGCCGCGCCGGGCGTCGGGCGCGATGAGTATGATAGACTGCAGAGCGT
TTATGTGTCCGCGCAAACCGGCGCCGGGCTTGAACTTTTACGCGATGCCCTGTCAGAAACGCTGCTCGCGGCACGCGAAA
CGGGTGCATCGGAAACGCCTTCTTCCCCATCCACAGTTCACTCTGCATAA

Upstream 100 bases:

>100_bases
GTCGGTGCACCGGGCTCGAACGTCCCGTCCGACGCCTTCGGGAGGCCAGCGGGTGATGCCCGCTCGCGGATGAAGCAGCC
GCGGAGGCGGGGAATCAGCG

Downstream 100 bases:

>100_bases
CAACATATGGCCTGGAACGACCCGCAATGGGGCAACAAGGGCAACCGCAACAACAGCGGTCCGCCCGATCTGGACGAGCT
TTGGCGGCGCCTGAACCAGC

Product: GTP-binding protein HflX

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 389; Mature: 389

Protein sequence:

>389_residues
MFDRHQGGERVVLAALDLGDPDFAESMAELRLLARGAGLDIRGEVQGRRSRPDAALFVGSGKADEIAALVAATDAEVVIF
NHELSPAQERNLERRLHCRVIDRVSLILDIFARRARSAEGKLQVELAQLQHLSTRLVRGWTHLERQRGGVGMRGPGEKQL
ETDRRLIGIRVKALRERLAKLGKQRRTQRRSRSRHRVLSVALVGYTNAGKSTLFNALTRAGTYAADQLFATLDTTTRKIF
LPRLADADEPGSGEVVLSDTVGFITRLPHDLVAAFRATLEATAEADLLLHVIDASSPVRERQIEAVDQVLREIGADAVPQ
LRVYNKLDLTAAAPGVGRDEYDRLQSVYVSAQTGAGLELLRDALSETLLAARETGASETPSSPSTVHSA

Sequences:

>Translated_389_residues
MFDRHQGGERVVLAALDLGDPDFAESMAELRLLARGAGLDIRGEVQGRRSRPDAALFVGSGKADEIAALVAATDAEVVIF
NHELSPAQERNLERRLHCRVIDRVSLILDIFARRARSAEGKLQVELAQLQHLSTRLVRGWTHLERQRGGVGMRGPGEKQL
ETDRRLIGIRVKALRERLAKLGKQRRTQRRSRSRHRVLSVALVGYTNAGKSTLFNALTRAGTYAADQLFATLDTTTRKIF
LPRLADADEPGSGEVVLSDTVGFITRLPHDLVAAFRATLEATAEADLLLHVIDASSPVRERQIEAVDQVLREIGADAVPQ
LRVYNKLDLTAAAPGVGRDEYDRLQSVYVSAQTGAGLELLRDALSETLLAARETGASETPSSPSTVHSA
>Mature_389_residues
MFDRHQGGERVVLAALDLGDPDFAESMAELRLLARGAGLDIRGEVQGRRSRPDAALFVGSGKADEIAALVAATDAEVVIF
NHELSPAQERNLERRLHCRVIDRVSLILDIFARRARSAEGKLQVELAQLQHLSTRLVRGWTHLERQRGGVGMRGPGEKQL
ETDRRLIGIRVKALRERLAKLGKQRRTQRRSRSRHRVLSVALVGYTNAGKSTLFNALTRAGTYAADQLFATLDTTTRKIF
LPRLADADEPGSGEVVLSDTVGFITRLPHDLVAAFRATLEATAEADLLLHVIDASSPVRERQIEAVDQVLREIGADAVPQ
LRVYNKLDLTAAAPGVGRDEYDRLQSVYVSAQTGAGLELLRDALSETLLAARETGASETPSSPSTVHSA

Specific function: Unknown

COG id: COG2262

COG function: function code R; GTPases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 G (guanine nucleotide-binding) domain [H]

Homologues:

Organism=Homo sapiens, GI310133118, Length=242, Percent_Identity=37.603305785124, Blast_Score=120, Evalue=2e-27,
Organism=Homo sapiens, GI310133116, Length=240, Percent_Identity=37.9166666666667, Blast_Score=119, Evalue=3e-27,
Organism=Homo sapiens, GI310124269, Length=223, Percent_Identity=39.4618834080717, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI310124267, Length=223, Percent_Identity=39.4618834080717, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI310124171, Length=223, Percent_Identity=39.4618834080717, Blast_Score=117, Evalue=1e-26,
Organism=Homo sapiens, GI310124169, Length=223, Percent_Identity=39.4618834080717, Blast_Score=117, Evalue=1e-26,
Organism=Escherichia coli, GI1790615, Length=369, Percent_Identity=56.639566395664, Blast_Score=382, Evalue=1e-107,
Organism=Caenorhabditis elegans, GI17561038, Length=291, Percent_Identity=31.2714776632302, Blast_Score=120, Evalue=1e-27,
Organism=Drosophila melanogaster, GI24650079, Length=331, Percent_Identity=33.5347432024169, Blast_Score=125, Evalue=5e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009022
- InterPro:   IPR016496
- InterPro:   IPR006073
- InterPro:   IPR002917 [H]

Pfam domain/function: PF01926 MMR_HSR1 [H]

EC number: NA

Molecular weight: Translated: 42521; Mature: 42521

Theoretical pI: Translated: 9.41; Mature: 9.41

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
0.8 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
1.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MFDRHQGGERVVLAALDLGDPDFAESMAELRLLARGAGLDIRGEVQGRRSRPDAALFVGS
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCEEEEEEC
GKADEIAALVAATDAEVVIFNHELSPAQERNLERRLHCRVIDRVSLILDIFARRARSAEG
CCHHHHHHHEEECCCEEEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLQVELAQLQHLSTRLVRGWTHLERQRGGVGMRGPGEKQLETDRRLIGIRVKALRERLAK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGKQRRTQRRSRSRHRVLSVALVGYTNAGKSTLFNALTRAGTYAADQLFATLDTTTRKIF
HHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
LPRLADADEPGSGEVVLSDTVGFITRLPHDLVAAFRATLEATAEADLLLHVIDASSPVRE
ECHHCCCCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHCCHHHEEEEECCCCCHHH
RQIEAVDQVLREIGADAVPQLRVYNKLDLTAAAPGVGRDEYDRLQSVYVSAQTGAGLELL
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCEECCCCCCCHHHHHHHHHHEECCCCCCHHHH
RDALSETLLAARETGASETPSSPSTVHSA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MFDRHQGGERVVLAALDLGDPDFAESMAELRLLARGAGLDIRGEVQGRRSRPDAALFVGS
CCCCCCCCCEEEEEEECCCCHHHHHHHHHHHHHHHCCCCCEECCCCCCCCCCCEEEEEEC
GKADEIAALVAATDAEVVIFNHELSPAQERNLERRLHCRVIDRVSLILDIFARRARSAEG
CCHHHHHHHEEECCCEEEEEECCCCCHHHHCHHHHHHHHHHHHHHHHHHHHHHHHCCCCC
KLQVELAQLQHLSTRLVRGWTHLERQRGGVGMRGPGEKQLETDRRLIGIRVKALRERLAK
CEEEHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHH
LGKQRRTQRRSRSRHRVLSVALVGYTNAGKSTLFNALTRAGTYAADQLFATLDTTTRKIF
HHHHHHHHHHHHHHHHEEEEEEEEECCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHEE
LPRLADADEPGSGEVVLSDTVGFITRLPHDLVAAFRATLEATAEADLLLHVIDASSPVRE
ECHHCCCCCCCCCCEEEECHHHHHHHCCHHHHHHHHHHHHHHCCHHHEEEEECCCCCHHH
RQIEAVDQVLREIGADAVPQLRVYNKLDLTAAAPGVGRDEYDRLQSVYVSAQTGAGLELL
HHHHHHHHHHHHHCCCCCCCHHHHCCCCCEECCCCCCCHHHHHHHHHHEECCCCCCHHHH
RDALSETLLAARETGASETPSSPSTVHSA
HHHHHHHHHHHHHCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 8248183; 7610040; 9278503; 2020545; 3040675 [H]