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The map label for this gene is xcpR [H]

Identifier: 74316565

GI number: 74316565

Start: 571979

End: 573676

Strand: Reverse

Name: xcpR [H]

Synonym: Tbd_0547

Alternate gene names: 74316565

Gene position: 573676-571979 (Counterclockwise)

Preceding gene: 74316566

Following gene: 74316564

Centisome position: 19.72

GC content: 66.14

Gene sequence:

>1698_bases
ATGGAACGCCGCAAGAAACTGCGCATGGGCGAAACCCTGGTGTCCCAGGGGCTCATCACGCTCGACCAGCTGCGCATCGG
CCTCAAGGAGCAAAAGGCCACGGGCCTGCCGATCGGCCGCCAGCTCGTCGCGCTCGGGTTCATCACCGAGGCGGTGCTGC
GCGACCAGCTCGCGAACGCGCTCGGCAGCCAGGGCATCGACCTGACCCAGGTCGTCGCCGACCCCGAAGCGCTGCATCTG
GTGCCCGAGGATTTTGCGCGCCGCCATCATCTGCTGCCGATCGCCCACGACGCGGCGCGGAACGTGCTGACGCTTGCGAC
GACCGACATGTTCAACGTCGTCGCGCTCGACCAGCTCAAGGCCGGACTCGGCGGCCATCTCGAAATCGACGCGCTGCTCG
CCGGCGAAGCCCAGCTGCTCGAGTGCATCGACAAGTTCTACGGCTTCGACCTCTCGCTCGACGGCATCCTGCGCGAAATC
GAAACCGGCGAAGTCGACTACGCCAGCCTGAATCCCGAGACCGAGGAATACACGCAGCCCGTCGTGCGACTCGTCGGCGC
GCTGCTGACCGATGCCGTCAAGCGCGAATCGTCCGACATCCACTTCGAACCCGAGCATGCCTTCCTGCGTATCCGCTACC
GCATCGACGGCGTGCTCGAACAGATCCGCAGCCTGCACAAGACCTATTGGCCGGGCATCCTCGTCCGCCTCAAGGTGCTC
TCGGGCATGAACATCGCCGAGACGCGCGCGCCGCAGGACGGCCGCATGTCGCTCACGCTGAACGGCCGCCCGATCGACTT
CCGCGTCTCCTCGCAGCCCGGCATTCACGGCGAAAACCTCGTCCTGCGCATCCTCGACCGCGAAAAATCCATCATGCCGC
TCGAGCAGATGGGCTTCACCGCCGACGCGCTGCGCGAACTGCAGCTGATGATGGCGCGCCCCGAAGGCATTCTGGTCGTC
ACCGGCCCGACCGGCTCGGGCAAGACGACGACGCTCTACTCGATGCTCTCGCATCTCAACAACGAGACCGTGAACATCAT
GACGCTCGAGGATCCGGTCGAATATCCGGTCACGCTGATGCGCCAGAGCTCGGTCAACGAGACGCTCAAGCTCGACTTCG
CCAACGGCATCCGCTCGATCATGCGGCAGGATCCGGACATCATCCTGGTCGGCGAAATCCGCGACAAGGACACGGCCGAA
ATGGCGTTCCGTGCGGCGATGACCGGGCACCAGGTGTTCACGACGCTGCACACCAACTCGGCGCTCGGCGTGTTTCCACG
CCTGATGGATATCGGCATCCAGCCCGGCATCCTGTCGGGCAACATCATCGGCGTGGTCGCACAACGCCTCGTGCGCAAGC
TGTGTCCGCGCTGCAGGGAGGCCTACAAGCCGGACGAAGACGAGGCCCGCATCCTCGGCATCGACGCGGCCGAGCCGACC
TGGATCTTCCGTGCAACGGGCTGCCCCGCTTGCAGCCACAAGGGCTACCGGGGGCGGCTGGCGCTGATCGAACTGTTGCG
CATGGATCCCGAACTCGACGAGCTCGTCGCCAGCCACGCGCCCTTGCACGAGATTCGCCGCGCAGCGCTCAGGCACGGCT
ACCACCCGCTCGCCGAGGACGGCGTCAAGCGCGTGCTCGACGGCGTCACCTCGCTCGCCGAAGTCGCGCGCGTCGTCGAC
CTGACCGGGCGGGCCTGA

Upstream 100 bases:

>100_bases
AGCTACTACACGAAAGCCCTGGCGCTCGGCGGCGCTCACCGCTTCGATCGTGCGCAGGCCGAAGCGCGGGTGCAGCAACT
GCAACGGATGCGCTGACCGC

Downstream 100 bases:

>100_bases
CGATGCCGTTTTTCGACTACCGCGCCGTCGACCAGACCGGACGCAACGTGCGCGGGACGCTGTCGGCGGTCAACGACGTC
GACCTCGAACTGCGGCTCAA

Product: ATPase, type IV pilus assembly protein PilB

Products: NA

Alternate protein names: Type II traffic warden ATPase [H]

Number of amino acids: Translated: 565; Mature: 565

Protein sequence:

>565_residues
MERRKKLRMGETLVSQGLITLDQLRIGLKEQKATGLPIGRQLVALGFITEAVLRDQLANALGSQGIDLTQVVADPEALHL
VPEDFARRHHLLPIAHDAARNVLTLATTDMFNVVALDQLKAGLGGHLEIDALLAGEAQLLECIDKFYGFDLSLDGILREI
ETGEVDYASLNPETEEYTQPVVRLVGALLTDAVKRESSDIHFEPEHAFLRIRYRIDGVLEQIRSLHKTYWPGILVRLKVL
SGMNIAETRAPQDGRMSLTLNGRPIDFRVSSQPGIHGENLVLRILDREKSIMPLEQMGFTADALRELQLMMARPEGILVV
TGPTGSGKTTTLYSMLSHLNNETVNIMTLEDPVEYPVTLMRQSSVNETLKLDFANGIRSIMRQDPDIILVGEIRDKDTAE
MAFRAAMTGHQVFTTLHTNSALGVFPRLMDIGIQPGILSGNIIGVVAQRLVRKLCPRCREAYKPDEDEARILGIDAAEPT
WIFRATGCPACSHKGYRGRLALIELLRMDPELDELVASHAPLHEIRRAALRHGYHPLAEDGVKRVLDGVTSLAEVARVVD
LTGRA

Sequences:

>Translated_565_residues
MERRKKLRMGETLVSQGLITLDQLRIGLKEQKATGLPIGRQLVALGFITEAVLRDQLANALGSQGIDLTQVVADPEALHL
VPEDFARRHHLLPIAHDAARNVLTLATTDMFNVVALDQLKAGLGGHLEIDALLAGEAQLLECIDKFYGFDLSLDGILREI
ETGEVDYASLNPETEEYTQPVVRLVGALLTDAVKRESSDIHFEPEHAFLRIRYRIDGVLEQIRSLHKTYWPGILVRLKVL
SGMNIAETRAPQDGRMSLTLNGRPIDFRVSSQPGIHGENLVLRILDREKSIMPLEQMGFTADALRELQLMMARPEGILVV
TGPTGSGKTTTLYSMLSHLNNETVNIMTLEDPVEYPVTLMRQSSVNETLKLDFANGIRSIMRQDPDIILVGEIRDKDTAE
MAFRAAMTGHQVFTTLHTNSALGVFPRLMDIGIQPGILSGNIIGVVAQRLVRKLCPRCREAYKPDEDEARILGIDAAEPT
WIFRATGCPACSHKGYRGRLALIELLRMDPELDELVASHAPLHEIRRAALRHGYHPLAEDGVKRVLDGVTSLAEVARVVD
LTGRA
>Mature_565_residues
MERRKKLRMGETLVSQGLITLDQLRIGLKEQKATGLPIGRQLVALGFITEAVLRDQLANALGSQGIDLTQVVADPEALHL
VPEDFARRHHLLPIAHDAARNVLTLATTDMFNVVALDQLKAGLGGHLEIDALLAGEAQLLECIDKFYGFDLSLDGILREI
ETGEVDYASLNPETEEYTQPVVRLVGALLTDAVKRESSDIHFEPEHAFLRIRYRIDGVLEQIRSLHKTYWPGILVRLKVL
SGMNIAETRAPQDGRMSLTLNGRPIDFRVSSQPGIHGENLVLRILDREKSIMPLEQMGFTADALRELQLMMARPEGILVV
TGPTGSGKTTTLYSMLSHLNNETVNIMTLEDPVEYPVTLMRQSSVNETLKLDFANGIRSIMRQDPDIILVGEIRDKDTAE
MAFRAAMTGHQVFTTLHTNSALGVFPRLMDIGIQPGILSGNIIGVVAQRLVRKLCPRCREAYKPDEDEARILGIDAAEPT
WIFRATGCPACSHKGYRGRLALIELLRMDPELDELVASHAPLHEIRRAALRHGYHPLAEDGVKRVLDGVTSLAEVARVVD
LTGRA

Specific function: Involved in a general secretion pathway (GSP) for the export of proteins. Required for the translocation of a variety of enzymes across the outer membrane [H]

COG id: COG2804

COG function: function code NU; Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB

Gene ontology:

Cell location: Cytoplasm (Probable) [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the GSP E family [H]

Homologues:

Organism=Escherichia coli, GI1789723, Length=447, Percent_Identity=40.4921700223714, Blast_Score=339, Evalue=3e-94,
Organism=Escherichia coli, GI1786296, Length=392, Percent_Identity=39.030612244898, Blast_Score=277, Evalue=1e-75,
Organism=Escherichia coli, GI87082188, Length=184, Percent_Identity=41.8478260869565, Blast_Score=110, Evalue=2e-25,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003593
- InterPro:   IPR013369
- InterPro:   IPR001482 [H]

Pfam domain/function: PF00437 GSPII_E [H]

EC number: NA

Molecular weight: Translated: 62561; Mature: 62561

Theoretical pI: Translated: 6.08; Mature: 6.08

Prosite motif: PS00662 T2SP_E

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.9 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MERRKKLRMGETLVSQGLITLDQLRIGLKEQKATGLPIGRQLVALGFITEAVLRDQLANA
CCHHHHHHHHHHHHHCCCHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGSQGIDLTQVVADPEALHLVPEDFARRHHLLPIAHDAARNVLTLATTDMFNVVALDQLK
HCCCCCCHHHHHCCCHHEEECCHHHHHHHCCCCEEHHHHCCEEEEEEHHHHHHHHHHHHH
AGLGGHLEIDALLAGEAQLLECIDKFYGFDLSLDGILREIETGEVDYASLNPETEEYTQP
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHH
VVRLVGALLTDAVKRESSDIHFEPEHAFLRIRYRIDGVLEQIRSLHKTYWPGILVRLKVL
HHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SGMNIAETRAPQDGRMSLTLNGRPIDFRVSSQPGIHGENLVLRILDREKSIMPLEQMGFT
CCCCHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHCCC
ADALRELQLMMARPEGILVVTGPTGSGKTTTLYSMLSHLNNETVNIMTLEDPVEYPVTLM
HHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
RQSSVNETLKLDFANGIRSIMRQDPDIILVGEIRDKDTAEMAFRAAMTGHQVFTTLHTNS
HHCCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCC
ALGVFPRLMDIGIQPGILSGNIIGVVAQRLVRKLCPRCREAYKPDEDEARILGIDAAEPT
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
WIFRATGCPACSHKGYRGRLALIELLRMDPELDELVASHAPLHEIRRAALRHGYHPLAED
EEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCCCCHHHH
GVKRVLDGVTSLAEVARVVDLTGRA
HHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure
MERRKKLRMGETLVSQGLITLDQLRIGLKEQKATGLPIGRQLVALGFITEAVLRDQLANA
CCHHHHHHHHHHHHHCCCHHHHHHHHCHHHHCCCCCCCHHHHHHHHHHHHHHHHHHHHHH
LGSQGIDLTQVVADPEALHLVPEDFARRHHLLPIAHDAARNVLTLATTDMFNVVALDQLK
HCCCCCCHHHHHCCCHHEEECCHHHHHHHCCCCEEHHHHCCEEEEEEHHHHHHHHHHHHH
AGLGGHLEIDALLAGEAQLLECIDKFYGFDLSLDGILREIETGEVDYASLNPETEEYTQP
CCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCEEEECCCCCHHHHHHH
VVRLVGALLTDAVKRESSDIHFEPEHAFLRIRYRIDGVLEQIRSLHKTYWPGILVRLKVL
HHHHHHHHHHHHHHCCCCCCEECCCCEEEEEEHHHHHHHHHHHHHHHHHCCHHHHHHHHH
SGMNIAETRAPQDGRMSLTLNGRPIDFRVSSQPGIHGENLVLRILDREKSIMPLEQMGFT
CCCCHHHCCCCCCCCEEEEECCCEEEEEECCCCCCCCCCCEEEEECCCCCCCCHHHHCCC
ADALRELQLMMARPEGILVVTGPTGSGKTTTLYSMLSHLNNETVNIMTLEDPVEYPVTLM
HHHHHHHHHHHCCCCCEEEEECCCCCCCHHHHHHHHHHCCCCEEEEEEECCCCCCHHHHH
RQSSVNETLKLDFANGIRSIMRQDPDIILVGEIRDKDTAEMAFRAAMTGHQVFTTLHTNS
HHCCCCCEEEEEHHHHHHHHHHCCCCEEEEECCCCCHHHHHHHHHHHCCCCEEEEEECCC
ALGVFPRLMDIGIQPGILSGNIIGVVAQRLVRKLCPRCREAYKPDEDEARILGIDAAEPT
CHHHHHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCCCCCCCEEEEECCCCCC
WIFRATGCPACSHKGYRGRLALIELLRMDPELDELVASHAPLHEIRRAALRHGYHPLAED
EEEEECCCCCCCCCCCCCHHHHHHHHHCCCCHHHHHHCCCCHHHHHHHHHHCCCCCHHHH
GVKRVLDGVTSLAEVARVVDLTGRA
HHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 1588814; 10984043 [H]