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The map label for this gene is kdsC [H]

Identifier: 74316555

GI number: 74316555

Start: 561223

End: 561750

Strand: Reverse

Name: kdsC [H]

Synonym: Tbd_0537

Alternate gene names: 74316555

Gene position: 561750-561223 (Counterclockwise)

Preceding gene: 74316556

Following gene: 74316554

Centisome position: 19.31

GC content: 68.94

Gene sequence:

>528_bases
ATGGCCGACGACGCGATCGCCCGGGCGCGAAAAATCCGCCTCATCGCCTTCGACGTCGACGGCGTCATGACCGACGGCAC
GCTGTTCCTCGCCGACGACGGACAGGAATACAAGGGCTTCAACTCGCTCGACGGCCACGGCCTCAAGATGCTTCAGCGCA
GCGGCGTCGCGCTTGCAATCATCACCGGGCGGACGTCGCGCGTGGTCGAGCACCGCGCGCGCAACCTCGGCATCGACATC
GTTCATCAGGGCGCGCACGACAAGCTGGTCGTCTACCAGGCGCTCTGCCGCGAACTCGCCATCGACCCCGAGGCCACGGC
CTACATGGGCGACGACGTGGTCGACCTGCCGGTCATGCGCCGCGCCGGTCTCGCGATCACCGTCCCCGCAGCCCCCGAAC
TGGTGAAGGCCCACAGCCATTACACAACGCGGCGCGAGGCCGGGCGCGGCGCGGTCCGCGAAGCCTGCGAATTCCTGATG
CGCGCCCAGGGCACGCTCGACGCGGCGCTCGCCCCCTACCTGCAATGA

Upstream 100 bases:

>100_bases
TGGAGACGCTGAAAATCAACGGTCTGCTCGTCGTCGACGCCGACAATCGCCTGGTCGGCGCCCTCAACATGCACGACCTG
CTGAAAGCGGGGGTGGTGTG

Downstream 100 bases:

>100_bases
AGGCCCGCGGGCTGCGGGCGGCCGGTCCGACGCAATGATTTCCCGGGGTTCGCTGTGGCTGCCGCTCGCGATTCTGCTGT
TGCTCGCCGCGTTGAGCTTC

Product: phosphatase kdsC

Products: NA

Alternate protein names: KDO 8-P phosphatase [H]

Number of amino acids: Translated: 175; Mature: 174

Protein sequence:

>175_residues
MADDAIARARKIRLIAFDVDGVMTDGTLFLADDGQEYKGFNSLDGHGLKMLQRSGVALAIITGRTSRVVEHRARNLGIDI
VHQGAHDKLVVYQALCRELAIDPEATAYMGDDVVDLPVMRRAGLAITVPAAPELVKAHSHYTTRREAGRGAVREACEFLM
RAQGTLDAALAPYLQ

Sequences:

>Translated_175_residues
MADDAIARARKIRLIAFDVDGVMTDGTLFLADDGQEYKGFNSLDGHGLKMLQRSGVALAIITGRTSRVVEHRARNLGIDI
VHQGAHDKLVVYQALCRELAIDPEATAYMGDDVVDLPVMRRAGLAITVPAAPELVKAHSHYTTRREAGRGAVREACEFLM
RAQGTLDAALAPYLQ
>Mature_174_residues
ADDAIARARKIRLIAFDVDGVMTDGTLFLADDGQEYKGFNSLDGHGLKMLQRSGVALAIITGRTSRVVEHRARNLGIDIV
HQGAHDKLVVYQALCRELAIDPEATAYMGDDVVDLPVMRRAGLAITVPAAPELVKAHSHYTTRREAGRGAVREACEFLMR
AQGTLDAALAPYLQ

Specific function: Catalyzes the hydrolysis of KDO 8-P to KDO and inorganic phosphate [H]

COG id: COG1778

COG function: function code R; Low specificity phosphatase (HAD superfamily)

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the kdsC family [H]

Homologues:

Organism=Homo sapiens, GI8923900, Length=153, Percent_Identity=25.4901960784314, Blast_Score=70, Evalue=1e-12,
Organism=Escherichia coli, GI2367202, Length=166, Percent_Identity=46.3855421686747, Blast_Score=161, Evalue=2e-41,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR023214
- InterPro:   IPR013200
- InterPro:   IPR006549
- InterPro:   IPR010023 [H]

Pfam domain/function: PF08282 Hydrolase_3 [H]

EC number: =3.1.3.45 [H]

Molecular weight: Translated: 19026; Mature: 18895

Theoretical pI: Translated: 6.79; Mature: 6.79

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
3.4 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MADDAIARARKIRLIAFDVDGVMTDGTLFLADDGQEYKGFNSLDGHGLKMLQRSGVALAI
CCCHHHHHHHEEEEEEEECCCEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEE
ITGRTSRVVEHRARNLGIDIVHQGAHDKLVVYQALCRELAIDPEATAYMGDDVVDLPVMR
EECCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHH
RAGLAITVPAAPELVKAHSHYTTRREAGRGAVREACEFLMRAQGTLDAALAPYLQ
HCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCC
>Mature Secondary Structure 
ADDAIARARKIRLIAFDVDGVMTDGTLFLADDGQEYKGFNSLDGHGLKMLQRSGVALAI
CCHHHHHHHEEEEEEEECCCEEECCEEEEECCCCCCCCCCCCCCHHHHHHHHCCCEEEE
ITGRTSRVVEHRARNLGIDIVHQGAHDKLVVYQALCRELAIDPEATAYMGDDVVDLPVMR
EECCHHHHHHHHHHHCCEEEEECCCCCHHHHHHHHHHHHCCCCCCCEECCCCCCCCHHHH
RAGLAITVPAAPELVKAHSHYTTRREAGRGAVREACEFLMRAQGTLDAALAPYLQ
HCCEEEECCCCHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11586360; 12142430 [H]