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The map label for this gene is lptA [H]

Identifier: 74316553

GI number: 74316553

Start: 560078

End: 560611

Strand: Reverse

Name: lptA [H]

Synonym: Tbd_0535

Alternate gene names: 74316553

Gene position: 560611-560078 (Counterclockwise)

Preceding gene: 74316554

Following gene: 74316552

Centisome position: 19.27

GC content: 67.79

Gene sequence:

>534_bases
ATGCGAACCCCGATCACCCCCCTGTGCGCCGCGCTCTGGCTCGCGCTCCTGGCCGCGCCTGCGCATGCCGAGACCGCCGA
CCGCGACAAGCCGATCAATCTCGAAGCGGACACAGTGACGCTCGACGACATCAAAAAAGTCAGCGTCTACCAGGGCAATG
TGATTCTCACCCAGGGCACCCTGACGCTGCGCGCCGACCGCATGCAGTTGACGCAGAACGCCGCGGGCCTCGACAAGGTC
AGCGCGACCGGGCGCCCCGTCGCGTTCCGGCAGAAGGTCGACGGGCGCGACGAATTCATCGAGGGCTTCGCGGCGCGCAT
CGAATTCGACAACACGACGAGCGAACTCGACCTCATCGGCGACGCACGACTGCGCCGAGGCGAGGACGAGCTGCGCGGCG
CGCGGATTTCGTACAACAGCGACAGCGGTTTTTACAAGGTCGTCGGCCAGAACGGCGCCGGTAGCCCGGGCGGGCGCGTA
CGCGCGGTCATCCGCCCCAAACCGCGCGGCGAGCAGCCGGCAGCGCAACCATGA

Upstream 100 bases:

>100_bases
ACCGTGCGCGCAGGCGCCATGCACTACGACGCGCGGCTTCGCGTGATCAAACTGAGCGGACGGGTCCACACCCGTTACCT
TCCCCGGAGAAACTAGCGCC

Downstream 100 bases:

>100_bases
GTCAGATATCGGTTCAAGGCTTGCGCAAGACCTACGGCAAGCGCACCGTCGTGCACGACGTGTCGTTCGACGTCAAAAGC
GGCGAGGTCGTCGGGCTGCT

Product: OstA-like family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 177; Mature: 177

Protein sequence:

>177_residues
MRTPITPLCAALWLALLAAPAHAETADRDKPINLEADTVTLDDIKKVSVYQGNVILTQGTLTLRADRMQLTQNAAGLDKV
SATGRPVAFRQKVDGRDEFIEGFAARIEFDNTTSELDLIGDARLRRGEDELRGARISYNSDSGFYKVVGQNGAGSPGGRV
RAVIRPKPRGEQPAAQP

Sequences:

>Translated_177_residues
MRTPITPLCAALWLALLAAPAHAETADRDKPINLEADTVTLDDIKKVSVYQGNVILTQGTLTLRADRMQLTQNAAGLDKV
SATGRPVAFRQKVDGRDEFIEGFAARIEFDNTTSELDLIGDARLRRGEDELRGARISYNSDSGFYKVVGQNGAGSPGGRV
RAVIRPKPRGEQPAAQP
>Mature_177_residues
MRTPITPLCAALWLALLAAPAHAETADRDKPINLEADTVTLDDIKKVSVYQGNVILTQGTLTLRADRMQLTQNAAGLDKV
SATGRPVAFRQKVDGRDEFIEGFAARIEFDNTTSELDLIGDARLRRGEDELRGARISYNSDSGFYKVVGQNGAGSPGGRV
RAVIRPKPRGEQPAAQP

Specific function: Required for the translocation of lipopolysaccharide (LPS) from the inner membrane to the outer membrane. May act as a chaperone that facilitates LPS transfer across the aquaeous environment of the periplasm. Interacts specifically with the lipid A domain

COG id: COG1934

COG function: function code S; Uncharacterized protein conserved in bacteria

Gene ontology:

Cell location: Periplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the lptA family [H]

Homologues:

Organism=Escherichia coli, GI1789592, Length=186, Percent_Identity=31.1827956989247, Blast_Score=78, Evalue=3e-16,

Paralogues:

None

Copy number: 60 Molecules/Cell In: Stationary Phase, Rich Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014340
- InterPro:   IPR005653 [H]

Pfam domain/function: PF03968 OstA [H]

EC number: NA

Molecular weight: Translated: 19158; Mature: 19158

Theoretical pI: Translated: 8.47; Mature: 8.47

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.1 %Met     (Translated Protein)
1.7 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.1 %Met     (Mature Protein)
1.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRTPITPLCAALWLALLAAPAHAETADRDKPINLEADTVTLDDIKKVSVYQGNVILTQGT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHCEEEEEEECCEEEECCE
LTLRADRMQLTQNAAGLDKVSATGRPVAFRQKVDGRDEFIEGFAARIEFDNTTSELDLIG
EEEEHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHEEEEECCCCCEEEEEC
DARLRRGEDELRGARISYNSDSGFYKVVGQNGAGSPGGRVRAVIRPKPRGEQPAAQP
CHHHHCCHHHHCCCEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC
>Mature Secondary Structure
MRTPITPLCAALWLALLAAPAHAETADRDKPINLEADTVTLDDIKKVSVYQGNVILTQGT
CCCCCHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCCEEEHHHCEEEEEEECCEEEECCE
LTLRADRMQLTQNAAGLDKVSATGRPVAFRQKVDGRDEFIEGFAARIEFDNTTSELDLIG
EEEEHHHHHHHHCCCCCCCCCCCCCCEEEECCCCCHHHHHHHHHEEEEECCCCCEEEEEC
DARLRRGEDELRGARISYNSDSGFYKVVGQNGAGSPGGRVRAVIRPKPRGEQPAAQP
CHHHHCCHHHHCCCEEEECCCCCEEEEEECCCCCCCCCEEEEEECCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]