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The map label for this gene is yrvM [H]

Identifier: 74316540

GI number: 74316540

Start: 550735

End: 551538

Strand: Direct

Name: yrvM [H]

Synonym: Tbd_0522

Alternate gene names: 74316540

Gene position: 550735-551538 (Clockwise)

Preceding gene: 74316537

Following gene: 74316557

Centisome position: 18.93

GC content: 69.9

Gene sequence:

>804_bases
ATGGACGCGCCCCAGTTCGAACGCACCCGGATATTGCTCGATCCAGCCGAGCAGGCTCGGCTCGCGCGCGCACACGTCCT
CGTCGCGGGGCTCGGCGGCGTCGGCTCGTATTGCGCGGAGGCGCTTGCCCGCGCCGGGGTGGGGCGGCTGACCCTCGTCG
ACCACGACGTCGTCGCCGCGTCGAATATCAACCGCCAGCTTCCCGCGCTGCTGTCGACGGTCGGGCAGGCCAAGGTCGAC
GTCATGGCCGCGCGCATCCGCGACATCAATCCGGCGTGCGAAGTCGTCGTCGTGCGCGAATTCCTGATCCCCGAGACCGT
CGCCGAGCGCGTCCCGGCCGACGTCGACTTCGTCGTCGACTGCATCGACTCGCTCAACTGCAAGGTCGCGCTCGTCGCGA
GCAGCGTCGAACGCGGGCTCAACGTCGCTTCGAGCATGGGCGCGGGGAACAAGCTCGACCCGAGCCGCATCCGGCTGGCT
GACATTTCGAAAACCAGCATGTGCGCGCTCGCCGCGGTCATGCGCAAGCGGTTGCGCAAACGCGGCATCGCGAAAGGCGT
GCTGACCATTTTTTCGGACGAACCCGGGCGCGCGCCGCTGCCGCCGCAGCCGGTCGAGGGGCGCGGTCGCGCGCGCGCGG
TCAACGGCACGATCAGCTACATGCCGCCCTTGTTCGGCCTCATGCTGGCGGGGGCAGTCGTTCGGAAGATGATCGCTGGC
GGGTCGGCAGCCACGGAAGCCCCGGCGGTCGCCCCGCCGCCGCAAAACCCGGGCGAAAAAAACGCCGGCGCGGCCGGCGT
CTGA

Upstream 100 bases:

>100_bases
GCCGAAGCCGAGCCGAGTGAGCCAGGGGGTGAGCAGTCCGAGCACCAGCAGGGCTGCAAGCAGCGTAAGCAACCACTTCA
ACATGAGGAGATTTTAGTCG

Downstream 100 bases:

>100_bases
GCGGACAGGGAATCCGCTCAGGCGGGGTCGGCCTTGCCTGCGGCGCGTACGCGTAGAACCACGAGGCCGAGCGCGGCGAG
CAGCATGGCCCAGGTTTCGG

Product: HesA/MoeB/ThiF family protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 267; Mature: 267

Protein sequence:

>267_residues
MDAPQFERTRILLDPAEQARLARAHVLVAGLGGVGSYCAEALARAGVGRLTLVDHDVVAASNINRQLPALLSTVGQAKVD
VMAARIRDINPACEVVVVREFLIPETVAERVPADVDFVVDCIDSLNCKVALVASSVERGLNVASSMGAGNKLDPSRIRLA
DISKTSMCALAAVMRKRLRKRGIAKGVLTIFSDEPGRAPLPPQPVEGRGRARAVNGTISYMPPLFGLMLAGAVVRKMIAG
GSAATEAPAVAPPPQNPGEKNAGAAGV

Sequences:

>Translated_267_residues
MDAPQFERTRILLDPAEQARLARAHVLVAGLGGVGSYCAEALARAGVGRLTLVDHDVVAASNINRQLPALLSTVGQAKVD
VMAARIRDINPACEVVVVREFLIPETVAERVPADVDFVVDCIDSLNCKVALVASSVERGLNVASSMGAGNKLDPSRIRLA
DISKTSMCALAAVMRKRLRKRGIAKGVLTIFSDEPGRAPLPPQPVEGRGRARAVNGTISYMPPLFGLMLAGAVVRKMIAG
GSAATEAPAVAPPPQNPGEKNAGAAGV
>Mature_267_residues
MDAPQFERTRILLDPAEQARLARAHVLVAGLGGVGSYCAEALARAGVGRLTLVDHDVVAASNINRQLPALLSTVGQAKVD
VMAARIRDINPACEVVVVREFLIPETVAERVPADVDFVVDCIDSLNCKVALVASSVERGLNVASSMGAGNKLDPSRIRLA
DISKTSMCALAAVMRKRLRKRGIAKGVLTIFSDEPGRAPLPPQPVEGRGRARAVNGTISYMPPLFGLMLAGAVVRKMIAG
GSAATEAPAVAPPPQNPGEKNAGAAGV

Specific function: Unknown

COG id: COG1179

COG function: function code H; Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the hesA/moeB/thiF family [H]

Homologues:

Organism=Homo sapiens, GI7657339, Length=108, Percent_Identity=45.3703703703704, Blast_Score=74, Evalue=1e-13,
Organism=Escherichia coli, GI1789177, Length=235, Percent_Identity=39.1489361702128, Blast_Score=152, Evalue=3e-38,
Organism=Escherichia coli, GI87082356, Length=156, Percent_Identity=33.974358974359, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1787048, Length=123, Percent_Identity=38.2113821138211, Blast_Score=71, Evalue=9e-14,
Organism=Saccharomyces cerevisiae, GI6322825, Length=212, Percent_Identity=34.4339622641509, Blast_Score=122, Evalue=8e-29,
Organism=Saccharomyces cerevisiae, GI6321790, Length=246, Percent_Identity=30.0813008130081, Blast_Score=118, Evalue=1e-27,
Organism=Saccharomyces cerevisiae, GI6321903, Length=155, Percent_Identity=31.6129032258064, Blast_Score=67, Evalue=4e-12,
Organism=Drosophila melanogaster, GI24582879, Length=137, Percent_Identity=33.5766423357664, Blast_Score=70, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR009036
- InterPro:   IPR016040
- InterPro:   IPR000594 [H]

Pfam domain/function: PF00899 ThiF [H]

EC number: NA

Molecular weight: Translated: 27825; Mature: 27825

Theoretical pI: Translated: 9.73; Mature: 9.73

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.9 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
4.9 %Cys+Met (Translated Protein)
1.9 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MDAPQFERTRILLDPAEQARLARAHVLVAGLGGVGSYCAEALARAGVGRLTLVDHDVVAA
CCCCCCCCEEEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHH
SNINRQLPALLSTVGQAKVDVMAARIRDINPACEVVVVREFLIPETVAERVPADVDFVVD
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
CIDSLNCKVALVASSVERGLNVASSMGAGNKLDPSRIRLADISKTSMCALAAVMRKRLRK
HHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHH
RGIAKGVLTIFSDEPGRAPLPPQPVEGRGRARAVNGTISYMPPLFGLMLAGAVVRKMIAG
CCHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GSAATEAPAVAPPPQNPGEKNAGAAGV
CCCCCCCCCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MDAPQFERTRILLDPAEQARLARAHVLVAGLGGVGSYCAEALARAGVGRLTLVDHDVVAA
CCCCCCCCEEEEECCHHHHHHHHHHHHEECCCCHHHHHHHHHHHCCCCEEEEECCCHHHH
SNINRQLPALLSTVGQAKVDVMAARIRDINPACEVVVVREFLIPETVAERVPADVDFVVD
HCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHHHHHCCCCHHHHHH
CIDSLNCKVALVASSVERGLNVASSMGAGNKLDPSRIRLADISKTSMCALAAVMRKRLRK
HHHCCCCEEEEEHHHHHHHHHHHHHCCCCCCCCHHHEEEECCCHHHHHHHHHHHHHHHHH
RGIAKGVLTIFSDEPGRAPLPPQPVEGRGRARAVNGTISYMPPLFGLMLAGAVVRKMIAG
CCHHHHHHHEECCCCCCCCCCCCCCCCCCCEEEECCCHHHHHHHHHHHHHHHHHHHHHHC
GSAATEAPAVAPPPQNPGEKNAGAAGV
CCCCCCCCCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9384377 [H]