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The map label for this gene is anmK

Identifier: 74316475

GI number: 74316475

Start: 473902

End: 475020

Strand: Reverse

Name: anmK

Synonym: Tbd_0457

Alternate gene names: 74316475

Gene position: 475020-473902 (Counterclockwise)

Preceding gene: 74316476

Following gene: 74316470

Centisome position: 16.32

GC content: 68.72

Gene sequence:

>1119_bases
TTGAGCGCAGTTCCCACGCATGAGGCCGAACCCTACGTCGGCCTCATGTCCGGCACCAGCCTTGACGGCATAGACGCGGT
CCTGGCCGAGATCGGCACCGGCAACCAAGTTCGCCTGCTCCGTACCCGATACATCCATTATCCCGACGACCTGCGCGCGC
AGTTGCTCGCGCTCCATACGCCGCAGGCCGACGAAGTCCATCTCGCGGCGCTTGCCGCCAACGCTCTGGCACGTCTCTAC
GCCGAAGCGGTCGGAGCGCTGCTTGAGGGCATCGATCCGGCCAAAATCCGCGCGATCGGCTGCCACGGCCAGACCCTGCG
CCACCGGCCGGGGGACGGCTATACGATCCAGATCGGAAACGCGTCGCTGCTGGCCGAACTCGCGGGCATCGCCGTCGTCT
CGGACTTCCGAAGCCGCGACATCGCGGCGGGCGGCCAGGGCGCGCCGCTGGTCCCGGCCTTCCACGCCCGCGTGCTGGCC
CATCCCGAGATTCACCGGGTCATTGCCAACGTCGGGGGGATCGCGAACATCACGGACCTTCCGCCGAATGGCCCGATCCG
GGGCTGGGATACGGGGCCGGGCAACATGCTCATGGACGCGTGGATCCATCGGCATCAGGGAAGCCGGTACGATCGCGATG
GGAGTTGGGCCGCCGAGGGCAGCGTGGCCGCCGGACTCCTGCAAGCATTGCTGCGCCACCCCTACCTGGAGCAGCGCCCG
CCGAAAAGCGCCGGGCGCGAGCAGTTCAACCTGGAAAGTCTCGACACGACGCTGGCCGGACTAGGGCAGAGGCTCGAGCC
GGGCACGGTACAGGCCACCCTGCTCGAATTTACCGCCGTCTCGCTCTGCGACGCCGTGACGCAGGAGTGCCGCGGCGCGC
AAGAACTCTACGTCTGTGGCGGCGGCGCGCACAACGGCGCCTTGATGCGGCGCATCGCGGCGCTCCTCCCGCACGTCCGC
GTCACGACGACTGCCGACCTGGGCATCGACCCGGATTGGGTCGAGGCGCTCGCGTTTGCTTGGCTCGCCCGGCAGACGAT
GCACGGCGAAGCCGGCAACCTGCCTGCCGTGACAGGCGCATGCGGGGAACGCATACTCGGCGCGATCCATCCGGCCTGA

Upstream 100 bases:

>100_bases
CGCCCTTGGCCGACGCGCAGCGCGCGCGCTTCCTCCAGCAGACCGCCGCCTGGTCTGAAAAACTCCACCTGCTGCGCGGC
ACCAATCTCGCCGCACTCGA

Downstream 100 bases:

>100_bases
AGCCGGACCGGAAACGAAAAAAGCGGCCGAAGCCGCTTTCTGCCGGGCGCGCAGCGCCTCAGGCCGAGAAGGACGAGCCG
CAGCCGCAGGTGGTCGTGGC

Product: anhydro-N-acetylmuramic acid kinase

Products: NA

Alternate protein names: AnhMurNAc kinase

Number of amino acids: Translated: 372; Mature: 371

Protein sequence:

>372_residues
MSAVPTHEAEPYVGLMSGTSLDGIDAVLAEIGTGNQVRLLRTRYIHYPDDLRAQLLALHTPQADEVHLAALAANALARLY
AEAVGALLEGIDPAKIRAIGCHGQTLRHRPGDGYTIQIGNASLLAELAGIAVVSDFRSRDIAAGGQGAPLVPAFHARVLA
HPEIHRVIANVGGIANITDLPPNGPIRGWDTGPGNMLMDAWIHRHQGSRYDRDGSWAAEGSVAAGLLQALLRHPYLEQRP
PKSAGREQFNLESLDTTLAGLGQRLEPGTVQATLLEFTAVSLCDAVTQECRGAQELYVCGGGAHNGALMRRIAALLPHVR
VTTTADLGIDPDWVEALAFAWLARQTMHGEAGNLPAVTGACGERILGAIHPA

Sequences:

>Translated_372_residues
MSAVPTHEAEPYVGLMSGTSLDGIDAVLAEIGTGNQVRLLRTRYIHYPDDLRAQLLALHTPQADEVHLAALAANALARLY
AEAVGALLEGIDPAKIRAIGCHGQTLRHRPGDGYTIQIGNASLLAELAGIAVVSDFRSRDIAAGGQGAPLVPAFHARVLA
HPEIHRVIANVGGIANITDLPPNGPIRGWDTGPGNMLMDAWIHRHQGSRYDRDGSWAAEGSVAAGLLQALLRHPYLEQRP
PKSAGREQFNLESLDTTLAGLGQRLEPGTVQATLLEFTAVSLCDAVTQECRGAQELYVCGGGAHNGALMRRIAALLPHVR
VTTTADLGIDPDWVEALAFAWLARQTMHGEAGNLPAVTGACGERILGAIHPA
>Mature_371_residues
SAVPTHEAEPYVGLMSGTSLDGIDAVLAEIGTGNQVRLLRTRYIHYPDDLRAQLLALHTPQADEVHLAALAANALARLYA
EAVGALLEGIDPAKIRAIGCHGQTLRHRPGDGYTIQIGNASLLAELAGIAVVSDFRSRDIAAGGQGAPLVPAFHARVLAH
PEIHRVIANVGGIANITDLPPNGPIRGWDTGPGNMLMDAWIHRHQGSRYDRDGSWAAEGSVAAGLLQALLRHPYLEQRPP
KSAGREQFNLESLDTTLAGLGQRLEPGTVQATLLEFTAVSLCDAVTQECRGAQELYVCGGGAHNGALMRRIAALLPHVRV
TTTADLGIDPDWVEALAFAWLARQTMHGEAGNLPAVTGACGERILGAIHPA

Specific function: Catalyzes the specific phosphorylation of 1,6-anhydro-N- acetylmuramic acid (anhMurNAc) with the simultaneous cleavage of the 1,6-anhydro ring, generating MurNAc-6-P. Is required for the utilization of anhMurNAc either imported from the medium or derived

COG id: COG2377

COG function: function code O; Predicted molecular chaperone distantly related to HSP70-fold metalloproteases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the anhydro-N-acetylmuramic acid kinase family

Homologues:

Organism=Escherichia coli, GI1787928, Length=367, Percent_Identity=48.7738419618529, Blast_Score=294, Evalue=6e-81,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): ANMK_THIDA (Q3SLK0)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314215.1
- ProteinModelPortal:   Q3SLK0
- SMR:   Q3SLK0
- STRING:   Q3SLK0
- GeneID:   3673085
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0457
- NMPDR:   fig|292415.3.peg.1028
- eggNOG:   COG2377
- HOGENOM:   HBG324434
- OMA:   GSHGQTV
- PhylomeDB:   Q3SLK0
- ProtClustDB:   PRK09585
- BioCyc:   TDEN292415:TBD_0457-MONOMER
- HAMAP:   MF_01270
- InterPro:   IPR005338

Pfam domain/function: PF03702 UPF0075

EC number: NA

Molecular weight: Translated: 39371; Mature: 39240

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
1.6 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
1.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSAVPTHEAEPYVGLMSGTSLDGIDAVLAEIGTGNQVRLLRTRYIHYPDDLRAQLLALHT
CCCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEEHCCCCCHHHHHHHHHCCC
PQADEVHLAALAANALARLYAEAVGALLEGIDPAKIRAIGCHGQTLRHRPGDGYTIQIGN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHCCCCCCCEEEEECC
ASLLAELAGIAVVSDFRSRDIAAGGQGAPLVPAFHARVLAHPEIHRVIANVGGIANITDL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
PPNGPIRGWDTGPGNMLMDAWIHRHQGSRYDRDGSWAAEGSVAAGLLQALLRHPYLEQRP
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
PKSAGREQFNLESLDTTLAGLGQRLEPGTVQATLLEFTAVSLCDAVTQECRGAQELYVCG
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGAHNGALMRRIAALLPHVRVTTTADLGIDPDWVEALAFAWLARQTMHGEAGNLPAVTGA
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
CGERILGAIHPA
HHHHHHHHCCCC
>Mature Secondary Structure 
SAVPTHEAEPYVGLMSGTSLDGIDAVLAEIGTGNQVRLLRTRYIHYPDDLRAQLLALHT
CCCCCCCCCCCEEEECCCCCCHHHHHHHHHCCCCEEEEEEEHCCCCCHHHHHHHHHCCC
PQADEVHLAALAANALARLYAEAVGALLEGIDPAKIRAIGCHGQTLRHRPGDGYTIQIGN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHEEEECCCCCHHCCCCCCCEEEEECC
ASLLAELAGIAVVSDFRSRDIAAGGQGAPLVPAFHARVLAHPEIHRVIANVGGIANITDL
HHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHCCHHHHHHHHHCCCCCCCCCC
PPNGPIRGWDTGPGNMLMDAWIHRHQGSRYDRDGSWAAEGSVAAGLLQALLRHPYLEQRP
CCCCCCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHCCCCCCCC
PKSAGREQFNLESLDTTLAGLGQRLEPGTVQATLLEFTAVSLCDAVTQECRGAQELYVCG
CCCCCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEC
GGAHNGALMRRIAALLPHVRVTTTADLGIDPDWVEALAFAWLARQTMHGEAGNLPAVTGA
CCCCCHHHHHHHHHHCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCHHH
CGERILGAIHPA
HHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA