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The map label for this gene is ybhO [H]

Identifier: 74316464

GI number: 74316464

Start: 465871

End: 467061

Strand: Direct

Name: ybhO [H]

Synonym: Tbd_0446

Alternate gene names: 74316464

Gene position: 465871-467061 (Clockwise)

Preceding gene: 74316463

Following gene: 74316466

Centisome position: 16.01

GC content: 66.41

Gene sequence:

>1191_bases
ATGACCCCGCGCGGTCCCTGGTCGCGGCTGTTTTTTCGCCGCGTCGACATGGTTTCGGGCAACCACCTGCGGCTGTTGCA
GAGCGGGGCCGACTACTTCCCTGCGCTGATCGCCGCGTTCGACGCCGCCCGCGCCGAAATCTATCTTGAAACCTATATCT
TCAACGCCGACTCGACGGCCGAGGCCGTGCGCGACGCGCTCGTTCGCGCCGCGCAGCGCGGCGTGCAGGTGCGCGTCCTG
ATCGACGCGATCGGTTCGCGTGAACTGCCTGCCGCGTGGCTGGAAGCACTGAAGACGGCGGGCGTCGCCGTCCTCAAGTA
CCGGCCGCTGGTCACCGGCTGGCGCTCGAATCCGAAAAGTCTGCGCCGATTGCACCGCAAGGTCGCGGTCGTCGACGCGC
GCATCGCTTTTGTCGGCGGCATGAATCTGCTCGACGATTTCGAGCCGATTCGCTTTCCTGTCGCGCGTTTCGACTTCAGC
GTCGAAGTGCAGGGGCCGCTGATCGTGGCGATCCATCAAAGTGTGCACCACCTGTGGCGTCTGGTCGCCTTGAGCCAACT
GCAGCCAATCGACCGCAAGCATTCGGTTCACCCTTCCTGGCCGACCGACGGCCGCGTCCGCGCGGCTTTCGTGACGCGCG
ACAGCTTTGCCCATCGGCGTGACATCGAGCGCAGCTACCTGACGGCGCTTGCGCTCGCGCGCAGCGACATCCTGATTGCG
AACGCCTATTTTCTGCCCGGCAACCGCTTCCGCAAGCTGCTGAAAAAAGCCGCGGCGCGTGGGGTGCGCGTGCAGCTGCT
CGTGCAGGGGCATACCGACCATCCTTTTTTTCAGGCGGCGTCGCGCGCGCTCTACCAGGATCTTCTAGTCGCCGGCGTCA
GCATCCGCGAGTATCAGGCGAGCGAGTTGCACGCCAAGGTCGCGGTCGTCGATGACCACTGGGCGACGGTCGGGTCGAGC
AACATCGACCCGTTCAGTCTGATGCTCGCGCGCGAGGCGAACATCGTCGTCGACGACGTGGGGTTCGCCGCCGACCTGCG
CGAGCGCCTGCAGCGCGCGGTGGACGAATCGGCCGCGCTCAGTGCCGCCGACTGGAAGATCCGTCCCTGGCGCCAGCGCC
TGGCCTCGCGGCTTGCCTACGGGCTCGTGCGCTTTCTGCTTGGCGTCGCGCGGCTCGGGCGCTGGCTGTAA

Upstream 100 bases:

>100_bases
TGCGCCGCTTCACGGTCAAAGCTGTCGAGGTCCATTCGGGTACCCTGTGGCGCGGGGTCTCCGATCACGCTGCGCTGACT
GCGACGCTTAGCGCCGCAGC

Downstream 100 bases:

>100_bases
CGCTGTCGTCCCAGCCGGGTTGCGTCGGGGGCGAGGCGCTGTAGCAGCAGCGTCGCCAGCATGGCGCAAGCCGCGTCAGA
GCTTCGCCGCCTCGAATGTA

Product: phospholipase D/transphosphatidylase

Products: NA

Alternate protein names: CL synthase [H]

Number of amino acids: Translated: 396; Mature: 395

Protein sequence:

>396_residues
MTPRGPWSRLFFRRVDMVSGNHLRLLQSGADYFPALIAAFDAARAEIYLETYIFNADSTAEAVRDALVRAAQRGVQVRVL
IDAIGSRELPAAWLEALKTAGVAVLKYRPLVTGWRSNPKSLRRLHRKVAVVDARIAFVGGMNLLDDFEPIRFPVARFDFS
VEVQGPLIVAIHQSVHHLWRLVALSQLQPIDRKHSVHPSWPTDGRVRAAFVTRDSFAHRRDIERSYLTALALARSDILIA
NAYFLPGNRFRKLLKKAAARGVRVQLLVQGHTDHPFFQAASRALYQDLLVAGVSIREYQASELHAKVAVVDDHWATVGSS
NIDPFSLMLAREANIVVDDVGFAADLRERLQRAVDESAALSAADWKIRPWRQRLASRLAYGLVRFLLGVARLGRWL

Sequences:

>Translated_396_residues
MTPRGPWSRLFFRRVDMVSGNHLRLLQSGADYFPALIAAFDAARAEIYLETYIFNADSTAEAVRDALVRAAQRGVQVRVL
IDAIGSRELPAAWLEALKTAGVAVLKYRPLVTGWRSNPKSLRRLHRKVAVVDARIAFVGGMNLLDDFEPIRFPVARFDFS
VEVQGPLIVAIHQSVHHLWRLVALSQLQPIDRKHSVHPSWPTDGRVRAAFVTRDSFAHRRDIERSYLTALALARSDILIA
NAYFLPGNRFRKLLKKAAARGVRVQLLVQGHTDHPFFQAASRALYQDLLVAGVSIREYQASELHAKVAVVDDHWATVGSS
NIDPFSLMLAREANIVVDDVGFAADLRERLQRAVDESAALSAADWKIRPWRQRLASRLAYGLVRFLLGVARLGRWL
>Mature_395_residues
TPRGPWSRLFFRRVDMVSGNHLRLLQSGADYFPALIAAFDAARAEIYLETYIFNADSTAEAVRDALVRAAQRGVQVRVLI
DAIGSRELPAAWLEALKTAGVAVLKYRPLVTGWRSNPKSLRRLHRKVAVVDARIAFVGGMNLLDDFEPIRFPVARFDFSV
EVQGPLIVAIHQSVHHLWRLVALSQLQPIDRKHSVHPSWPTDGRVRAAFVTRDSFAHRRDIERSYLTALALARSDILIAN
AYFLPGNRFRKLLKKAAARGVRVQLLVQGHTDHPFFQAASRALYQDLLVAGVSIREYQASELHAKVAVVDDHWATVGSSN
IDPFSLMLAREANIVVDDVGFAADLRERLQRAVDESAALSAADWKIRPWRQRLASRLAYGLVRFLLGVARLGRWL

Specific function: Catalyzes, in vitro, the phosphatidyl group transfer from one phosphatidylglycerol molecule to another to form cardiolipin (CL) (diphosphatidylglycerol) and glycerol [H]

COG id: COG1502

COG function: function code I; Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthases and related enzymes

Gene ontology:

Cell location: Cell membrane; Peripheral membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 PLD phosphodiesterase domains [H]

Homologues:

Organism=Escherichia coli, GI1787007, Length=371, Percent_Identity=40.7008086253369, Blast_Score=250, Evalue=1e-67,
Organism=Escherichia coli, GI1787502, Length=386, Percent_Identity=30.3108808290155, Blast_Score=152, Evalue=3e-38,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001736 [H]

Pfam domain/function: PF00614 PLDc [H]

EC number: 2.7.8.-

Molecular weight: Translated: 44488; Mature: 44357

Theoretical pI: Translated: 11.05; Mature: 11.05

Prosite motif: PS50035 PLD

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.0 %Cys     (Translated Protein)
1.0 %Met     (Translated Protein)
1.0 %Cys+Met (Translated Protein)
0.0 %Cys     (Mature Protein)
0.8 %Met     (Mature Protein)
0.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTPRGPWSRLFFRRVDMVSGNHLRLLQSGADYFPALIAAFDAARAEIYLETYIFNADSTA
CCCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCHH
EAVRDALVRAAQRGVQVRVLIDAIGSRELPAAWLEALKTAGVAVLKYRPLVTGWRSNPKS
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCHHCCCCCCHHH
LRRLHRKVAVVDARIAFVGGMNLLDDFEPIRFPVARFDFSVEVQGPLIVAIHQSVHHLWR
HHHHHHHHHHHHHHHHEECCCHHHHCCCHHHCCHHHEEEEEEECCCEEEEEHHHHHHHHH
LVALSQLQPIDRKHSVHPSWPTDGRVRAAFVTRDSFAHRRDIERSYLTALALARSDILIA
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCEEEE
NAYFLPGNRFRKLLKKAAARGVRVQLLVQGHTDHPFFQAASRALYQDLLVAGVSIREYQA
EEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
SELHAKVAVVDDHWATVGSSNIDPFSLMLAREANIVVDDVGFAADLRERLQRAVDESAAL
HHHHEEEEEEECCHHCCCCCCCCHHHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCC
SAADWKIRPWRQRLASRLAYGLVRFLLGVARLGRWL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC
>Mature Secondary Structure 
TPRGPWSRLFFRRVDMVSGNHLRLLQSGADYFPALIAAFDAARAEIYLETYIFNADSTA
CCCCHHHHHHHHHHHHCCCCCEEEECCCCHHHHHHHHHHHHHHHEEEEEEEEECCCCHH
EAVRDALVRAAQRGVQVRVLIDAIGSRELPAAWLEALKTAGVAVLKYRPLVTGWRSNPKS
HHHHHHHHHHHHCCCEEEEEEECCCCCCCCHHHHHHHHHCCEEEEEECCHHCCCCCCHHH
LRRLHRKVAVVDARIAFVGGMNLLDDFEPIRFPVARFDFSVEVQGPLIVAIHQSVHHLWR
HHHHHHHHHHHHHHHHEECCCHHHHCCCHHHCCHHHEEEEEEECCCEEEEEHHHHHHHHH
LVALSQLQPIDRKHSVHPSWPTDGRVRAAFVTRDSFAHRRDIERSYLTALALARSDILIA
HHHHHHCCCCCCCCCCCCCCCCCCCEEEEEEECHHHHHHHHHHHHHHHHHHHHHCCEEEE
NAYFLPGNRFRKLLKKAAARGVRVQLLVQGHTDHPFFQAASRALYQDLLVAGVSIREYQA
EEEECCCHHHHHHHHHHHCCCCEEEEEEECCCCCHHHHHHHHHHHHHHHHHCCHHHHHHH
SELHAKVAVVDDHWATVGSSNIDPFSLMLAREANIVVDDVGFAADLRERLQRAVDESAAL
HHHHEEEEEEECCHHCCCCCCCCHHHHEEECCCCEEEECCCHHHHHHHHHHHHHHHHHCC
SAADWKIRPWRQRLASRLAYGLVRFLLGVARLGRWL
CCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11677608; 12644504 [H]