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The map label for this gene is rpoC

Identifier: 74316417

GI number: 74316417

Start: 428560

End: 432756

Strand: Direct

Name: rpoC

Synonym: Tbd_0399

Alternate gene names: 74316417

Gene position: 428560-432756 (Clockwise)

Preceding gene: 74316416

Following gene: 74316418

Centisome position: 14.73

GC content: 64.93

Gene sequence:

>4197_bases
ATGAAAGCACTGTTGGATCTATTCAAGCAGGCCACCCACGAGGAAGAATTCGACGCCATCAAGATCGGCCTGGCGTCGCC
GGACAAGATCCGCTCCTGGTCGTACGGCGAAGTGAAGAAGCCGGAGACCATCAACTACCGTACCTTCAAGCCGGAGCGTG
ACGGCCTGTTTTGCGCCAAGATCTTCGGTCCGGTCAAGGACTACGAGTGCCTGTGCGGCAAGTACAAGCGCCTCAAGCAC
CGCGGCGTGATCTGCGAGAAGTGCGGCGTCGAAGTGACGCTATCGAAGGTGCGTCGCGAGCGCATGGGCCACATCGAGCT
CGCCAGCCCGGTCGCCCACATCTGGTTCCTGAAGTCGCTGCCGAGCCGGCTCGGCATGGTGCTCGACATGACGCTGCGCG
ACATCGAGCGCGTGCTCTACTTCGAAGGCTTCGTCGTCGTCGAGCCCGGCATGACGCCGCTCAACCGCGGCCAGCTGCTG
ACCGAGGAGGACTACCTCGGCAAGCTCGAGGAGTACGGCGACGAGTTCAAGGCGCTCATGGGCGCCGAGGGTGTGCGTGA
GCTGTTGCGTTCGCTCGACGTCGCCAGCGAAGTCGAAACCCTGCATTCCGAAATCAGCAAGACCGGCTCCGACACCAAAC
TCAAGAAGCTGTCCAAGCGCCTCAAGATCCTCGAGGGTTTCCAGAAGTCGGGCATCAAGCCCGAATGGATGATCCTCGAG
GTGCTGCCGGTGCTGCCGCCGGAGCTGCGTCCGCTGGTGCCGTTGGACGGCGGCCGCTTCGCGACCTCCGACCTCAACGA
TCTCTACCGCCGCGTCATCAACCGCAACAACCGCCTGAAGCGGCTGCTGGAGCTGAAGGCGCCCGAGATCATCGTGCGCA
ACGAAAAGCGCATGCTGCAGGAAGCGGTCGATTCGCTGCTCGACAACGGCCGTCGCGGCAAGGCGATGACCGGCGCCAAC
AAGCGTCCGCTGAAGTCGCTGGCCGACATGATCAAGGGCAAGAGCGGCCGCTTCCGTCAGAACCTGCTCGGCAAGCGCGT
CGACTACTCGGGCCGTTCGGTCATCGTCGTCGGCCCGACGCTCAAGCTGCATCAGTGTGGCCTGCCGAAGAAGATGGCGC
TCGAACTCTTCAAGCCCTTCATCTTCAACCGCCTCGAGGTATTGGGGCTCGCGACCACGATCAAGGCCGCGAAGAAGATG
GTCGAGGACGAAGAGCCGATCGTCTGGGATCTGCTCGAAGAGGTCATCCGCGAGCATCCGGTGATGCTGAACCGCGCGCC
GACGCTGCACCGCCTGGGCATCCAGGCGTTCGAGCCCGTGCTGATCGAAGGCAAGGCGATCCAGCTGCATCCGCTCGTCT
GTGCGGCGTTCAACGCCGACTTCGACGGCGACCAGATGGCCGTCCACGTGCCGCTGTCGCTCGAAGCGCAGGCCGAAGCC
CGTACCCTGATGCTGGCGTCGAACAACGTGCTGTCGCCCGCCAACGGCGAGCCGATCATCGTCCCCTCGCAGGACATCGT
GCTGGGTCTCTATTACATGACGCGCGAGAAGGTGAATGCGAAGGGCGAGGGCATGATGTTCGCCGACGTGACCGAAGCGC
GCCGCGCCTACGACAACCGCGAGGCCGAACTGCATGCGCGCGTGACGGTGCGCATCAAGGAAGTGACGCTTGACGAGAAC
AAGAACCGCGTCGAGACCGTCAAGCGCGTCGAGACCACGCTCGGTCGCGCGCTGCTGTCCGAAATCCTGCCGCCGGGGCT
GCCCTTCAGCTTCGTCGACAAGGCGCTGAAGAAGAAGGAGATCTCCAAGCTCATCAACGCCAGCTTCCGCCGCTGTGGCC
TGCGCGAGACGGTGATCTTCGCCGACAAGCTGATGTACACCGGCTTCACGTTCGCGACCCGCGCGGGCATGTCGATCGCG
ATCAAGGACATGCTGATTCCGCAGGAGAAGGGCCAGATCCTCGGCGCGGCCGAAGCCGAAGTGAAGGAAATCGAATCGCA
GTACACCTCGGGCCTCGTCACCCAGGGCGAGCGCTACAACAAGGTCGTCGACATCTGGGGGCGCGCGGGCGACGCCGTCG
CCAAGGCGATGATGGGACAGCTCGGCGGCGAGAAGGTCACCGACCGTCAGGGCAAGGAAGTCACCCAGGAGTCGTTCAAC
GCGATCTACATGATGGCCGACTCGGGTGCGCGGGGCTCCGCTGCCCAGATCCGCCAGCTCGCGGGTATGCGCGGCCTGAT
GGCGAAGCCGGACGGCTCGATCATCGAGACGCCGATCACGGCGAACTTCCGCGAAGGCCTGAACATGCTTCAGTACTTCA
TCTCGACGCACGGCGCGCGCAAAGGCCTCGCCGACACCGCGCTGAAGACCGCGAACTCCGGCTACCTGACGCGCCGCCTG
GTCGACGTGACGCAGGATCTCGTGGTGACCGAGGACGACTGCGGCACCAAGAACGGCCTGCTCGTCAAGGCACTGGTCGA
GGGTGGCGAGGTCGTCGAGGCGCTGCGCGAGCGCATCCTCGGGCGCGTCGCGGCGAGCGACATCATCAATCCGGAAACGC
AGGAAACCGTTTTCGAAGCCGGTACCCTGCTATCCGAGGACGTGGTCGACACCATCGAGGCGCTCGGCATCGACGAGGTG
CGCGTGCGCACGCCGTTGACCTGCGAGACGCGCTACGGCCTGTGCGCCAACTGCTACGGACGCGACCTCGGCCGCGGCTA
CCTCGTCAACGTCGGCGAGGCGGTCGGCGTGATCGCCGCGCAGTCGATCGGCGAGCCGGGCACCCAGCTCACGATGCGCA
CCTTCCACATCGGTGGTGCGGCCTCGCGAGCCGCGGCGGCGAGCCAGCTCGAAGCGAAGTCGAACGGCGCCGTGCAGTAC
ACCGCGACGATGCGTTACGTCACCAACGCGCGCAAGGAACTCGTGGCGATCTCGCGCAGCGGCGAAATTCTCATCGCCGA
CGACAGCGGCCGCGAGCGGGAGCGCCACAAGGTGCCGTACGGCGCGACGCTCATGGTCACCGACGGCGCCAAGATCAAGG
CCGGCGCCGTGCTCGCGACCTGGGACCCGCATACCCGTCCGATCATCACCGAGTACGCCGGCCGCGTGCGCTTCGAGAAC
GTCGAGGAAGGCGTGACGGTCGCCAAGCAGGTCGACGACGTCACCGGCCTGTCGACGCTCGTGGTCATCGATCCCAAGCG
CAAGAGCACGAGCACCAAGGGCGTGCGCCCGCAGGTCAAGCTGCTCGATGACGCCGGCAACGAATTGAAGATCGCGGGTA
CGGACACGCTCGTCAACATCACCTTCCAGATCGGCTCGATCATCACCGTGAAGGACGGTCAGGACGTGGCCGTGGGCGAC
GTGCTCGCGCGTATCCCGCAGGAAACGTCGAAGACCCGCGACATCACCGGCGGTCTACCGCGTGTGGCCGAGCTGTTCGA
GGCGCGTTCGCCAAAGGACGCCGGCGTGCTGGCCGAAGTCACCGGTACTGTGTCCTTCGGCAAGGACACCAAAGGCAAGC
AGCGCCTGGTCATCACCGACCTCGACGGCGTCGCGCACGAGTATCTGATCACGAAGGAGAAGCATGTCACCGCCCACGAC
GGCCAGATCGTCCAGAAGGGCGAAATGATCGTCGACGGCCCGGTCGATCCGCACGACATCCTGCGTCTGCAAGGCGTCGA
GGCGCTCGCCTCCTACATCACCGACGAAGTCCAGGACGTCTACCGTCTGCAGGGCGTGAAGATCAACGACAAGCACATCG
AGGTCATCGTGCGTCAGATGCTGCGTCGTGTCGTCGTCGCCGATCCGGGCGACACCGGCCTCATCCCGGGCGAGCAGGTC
GAGCGTTCGGAAGTGCTGCAGATCAACGACGAAATGATCGCCGCGGGCAAGGAGCCGGCGGTCTACGATCCGATCCTGCT
CGGCATCACCAAGGCGTCGCTGTCGACCGACTCGTTCATCTCGGCGGCTTCCTTCCAGGAAACGACCCGCGTCCTCACCG
AGGCGGCGATCATGGGCAAGAAGGACGAGCTGCGCGGGCTGAAGGAAAACGTGATCGTCGGCCGCCTTATCCCGGCGGGC
AGCGGCCTCGCCTACCACAACACCCGTCGCCGTCAGGCCGCGGGCGAGGACATGGGAGCCGACCGTTTGCTCGAGGGCGG
CGAAACCCCGGCGGCCGAGAATCAGGAAGTGGCTTGA

Upstream 100 bases:

>100_bases
CGGCATGCCCGAGTCCTTCAACGTGCTGGTGAAGGAAATCCGAAGCCTGGGCATCGACATCGATCTGGAACGTTATTAAT
TTTGGGGTGAGGACACAGCC

Downstream 100 bases:

>100_bases
CGCGGGAGGGGAATCCCTCTAAACTCACGCGTCTTTTTCCGGCCATACGTGGGATCCGGAAACGCAGGACTGTAGCCCGG
GACGGTGCCGCGCCAGAACG

Product: DNA-directed RNA polymerase subunit beta'

Products: NA

Alternate protein names: RNAP subunit beta'; RNA polymerase subunit beta'; Transcriptase subunit beta'

Number of amino acids: Translated: 1398; Mature: 1398

Protein sequence:

>1398_residues
MKALLDLFKQATHEEEFDAIKIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEGFVVVEPGMTPLNRGQLL
TEEDYLGKLEEYGDEFKALMGAEGVRELLRSLDVASEVETLHSEISKTGSDTKLKKLSKRLKILEGFQKSGIKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKKMALELFKPFIFNRLEVLGLATTIKAAKKM
VEDEEPIVWDLLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQAEA
RTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTREKVNAKGEGMMFADVTEARRAYDNREAELHARVTVRIKEVTLDEN
KNRVETVKRVETTLGRALLSEILPPGLPFSFVDKALKKKEISKLINASFRRCGLRETVIFADKLMYTGFTFATRAGMSIA
IKDMLIPQEKGQILGAAEAEVKEIESQYTSGLVTQGERYNKVVDIWGRAGDAVAKAMMGQLGGEKVTDRQGKEVTQESFN
AIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNMLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVTQDLVVTEDDCGTKNGLLVKALVEGGEVVEALRERILGRVAASDIINPETQETVFEAGTLLSEDVVDTIEALGIDEV
RVRTPLTCETRYGLCANCYGRDLGRGYLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQLEAKSNGAVQY
TATMRYVTNARKELVAISRSGEILIADDSGRERERHKVPYGATLMVTDGAKIKAGAVLATWDPHTRPIITEYAGRVRFEN
VEEGVTVAKQVDDVTGLSTLVVIDPKRKSTSTKGVRPQVKLLDDAGNELKIAGTDTLVNITFQIGSIITVKDGQDVAVGD
VLARIPQETSKTRDITGGLPRVAELFEARSPKDAGVLAEVTGTVSFGKDTKGKQRLVITDLDGVAHEYLITKEKHVTAHD
GQIVQKGEMIVDGPVDPHDILRLQGVEALASYITDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVADPGDTGLIPGEQV
ERSEVLQINDEMIAAGKEPAVYDPILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKKDELRGLKENVIVGRLIPAG
SGLAYHNTRRRQAAGEDMGADRLLEGGETPAAENQEVA

Sequences:

>Translated_1398_residues
MKALLDLFKQATHEEEFDAIKIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEGFVVVEPGMTPLNRGQLL
TEEDYLGKLEEYGDEFKALMGAEGVRELLRSLDVASEVETLHSEISKTGSDTKLKKLSKRLKILEGFQKSGIKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKKMALELFKPFIFNRLEVLGLATTIKAAKKM
VEDEEPIVWDLLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQAEA
RTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTREKVNAKGEGMMFADVTEARRAYDNREAELHARVTVRIKEVTLDEN
KNRVETVKRVETTLGRALLSEILPPGLPFSFVDKALKKKEISKLINASFRRCGLRETVIFADKLMYTGFTFATRAGMSIA
IKDMLIPQEKGQILGAAEAEVKEIESQYTSGLVTQGERYNKVVDIWGRAGDAVAKAMMGQLGGEKVTDRQGKEVTQESFN
AIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNMLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVTQDLVVTEDDCGTKNGLLVKALVEGGEVVEALRERILGRVAASDIINPETQETVFEAGTLLSEDVVDTIEALGIDEV
RVRTPLTCETRYGLCANCYGRDLGRGYLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQLEAKSNGAVQY
TATMRYVTNARKELVAISRSGEILIADDSGRERERHKVPYGATLMVTDGAKIKAGAVLATWDPHTRPIITEYAGRVRFEN
VEEGVTVAKQVDDVTGLSTLVVIDPKRKSTSTKGVRPQVKLLDDAGNELKIAGTDTLVNITFQIGSIITVKDGQDVAVGD
VLARIPQETSKTRDITGGLPRVAELFEARSPKDAGVLAEVTGTVSFGKDTKGKQRLVITDLDGVAHEYLITKEKHVTAHD
GQIVQKGEMIVDGPVDPHDILRLQGVEALASYITDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVADPGDTGLIPGEQV
ERSEVLQINDEMIAAGKEPAVYDPILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKKDELRGLKENVIVGRLIPAG
SGLAYHNTRRRQAAGEDMGADRLLEGGETPAAENQEVA
>Mature_1398_residues
MKALLDLFKQATHEEEFDAIKIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAKIFGPVKDYECLCGKYKRLKH
RGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSLPSRLGMVLDMTLRDIERVLYFEGFVVVEPGMTPLNRGQLL
TEEDYLGKLEEYGDEFKALMGAEGVRELLRSLDVASEVETLHSEISKTGSDTKLKKLSKRLKILEGFQKSGIKPEWMILE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQEAVDSLLDNGRRGKAMTGAN
KRPLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPTLKLHQCGLPKKMALELFKPFIFNRLEVLGLATTIKAAKKM
VEDEEPIVWDLLEEVIREHPVMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQAEA
RTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTREKVNAKGEGMMFADVTEARRAYDNREAELHARVTVRIKEVTLDEN
KNRVETVKRVETTLGRALLSEILPPGLPFSFVDKALKKKEISKLINASFRRCGLRETVIFADKLMYTGFTFATRAGMSIA
IKDMLIPQEKGQILGAAEAEVKEIESQYTSGLVTQGERYNKVVDIWGRAGDAVAKAMMGQLGGEKVTDRQGKEVTQESFN
AIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNMLQYFISTHGARKGLADTALKTANSGYLTRRL
VDVTQDLVVTEDDCGTKNGLLVKALVEGGEVVEALRERILGRVAASDIINPETQETVFEAGTLLSEDVVDTIEALGIDEV
RVRTPLTCETRYGLCANCYGRDLGRGYLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQLEAKSNGAVQY
TATMRYVTNARKELVAISRSGEILIADDSGRERERHKVPYGATLMVTDGAKIKAGAVLATWDPHTRPIITEYAGRVRFEN
VEEGVTVAKQVDDVTGLSTLVVIDPKRKSTSTKGVRPQVKLLDDAGNELKIAGTDTLVNITFQIGSIITVKDGQDVAVGD
VLARIPQETSKTRDITGGLPRVAELFEARSPKDAGVLAEVTGTVSFGKDTKGKQRLVITDLDGVAHEYLITKEKHVTAHD
GQIVQKGEMIVDGPVDPHDILRLQGVEALASYITDEVQDVYRLQGVKINDKHIEVIVRQMLRRVVVADPGDTGLIPGEQV
ERSEVLQINDEMIAAGKEPAVYDPILLGITKASLSTDSFISAASFQETTRVLTEAAIMGKKDELRGLKENVIVGRLIPAG
SGLAYHNTRRRQAAGEDMGADRLLEGGETPAAENQEVA

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0086

COG function: function code K; DNA-directed RNA polymerase, beta' subunit/160 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta' chain family

Homologues:

Organism=Homo sapiens, GI4505939, Length=576, Percent_Identity=27.4305555555556, Blast_Score=161, Evalue=4e-39,
Organism=Homo sapiens, GI39725938, Length=308, Percent_Identity=30.1948051948052, Blast_Score=127, Evalue=1e-28,
Organism=Homo sapiens, GI103471997, Length=225, Percent_Identity=31.5555555555556, Blast_Score=91, Evalue=6e-18,
Organism=Escherichia coli, GI2367335, Length=1378, Percent_Identity=68.0696661828737, Blast_Score=1918, Evalue=0.0,
Organism=Caenorhabditis elegans, GI71987878, Length=325, Percent_Identity=30.4615384615385, Blast_Score=147, Evalue=4e-35,
Organism=Caenorhabditis elegans, GI25145495, Length=318, Percent_Identity=30.188679245283, Blast_Score=142, Evalue=2e-33,
Organism=Saccharomyces cerevisiae, GI6320061, Length=539, Percent_Identity=25.7884972170686, Blast_Score=148, Evalue=8e-36,
Organism=Saccharomyces cerevisiae, GI6324917, Length=825, Percent_Identity=22.7878787878788, Blast_Score=139, Evalue=3e-33,
Organism=Saccharomyces cerevisiae, GI6324690, Length=316, Percent_Identity=30.379746835443, Blast_Score=134, Evalue=1e-31,
Organism=Drosophila melanogaster, GI281360912, Length=1023, Percent_Identity=25.0244379276637, Blast_Score=194, Evalue=4e-49,
Organism=Drosophila melanogaster, GI17530899, Length=574, Percent_Identity=27.0034843205575, Blast_Score=158, Evalue=2e-38,
Organism=Drosophila melanogaster, GI17647875, Length=329, Percent_Identity=27.9635258358663, Blast_Score=109, Evalue=1e-23,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): RPOC_THIDA (Q3SLQ5)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314157.1
- ProteinModelPortal:   Q3SLQ5
- STRING:   Q3SLQ5
- GeneID:   3671666
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0399
- NMPDR:   fig|292415.3.peg.852
- eggNOG:   COG0086
- HOGENOM:   HBG621785
- OMA:   FEARVPK
- PhylomeDB:   Q3SLQ5
- ProtClustDB:   PRK00566
- BioCyc:   TDEN292415:TBD_0399-MONOMER
- HAMAP:   MF_01322
- InterPro:   IPR000722
- InterPro:   IPR006592
- InterPro:   IPR007080
- InterPro:   IPR007066
- InterPro:   IPR007083
- InterPro:   IPR007081
- InterPro:   IPR012754
- SMART:   SM00663
- TIGRFAMs:   TIGR02386

Pfam domain/function: PF04997 RNA_pol_Rpb1_1; PF00623 RNA_pol_Rpb1_2; PF04983 RNA_pol_Rpb1_3; PF05000 RNA_pol_Rpb1_4; PF04998 RNA_pol_Rpb1_5

EC number: =2.7.7.6

Molecular weight: Translated: 153695; Mature: 153695

Theoretical pI: Translated: 7.08; Mature: 7.08

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKALLDLFKQATHEEEFDAIKIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEGFVVVEPGMTPLNRGQLLTEEDYLGKLEEYGDEFKALM
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
GAEGVRELLRSLDVASEVETLHSEISKTGSDTKLKKLSKRLKILEGFQKSGIKPEWMILE
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHHH
EAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPT
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCC
LKLHQCGLPKKMALELFKPFIFNRLEVLGLATTIKAAKKMVEDEEPIVWDLLEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQAEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCC
RTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTREKVNAKGEGMMFADVTEARRAYDNR
EEEEEECCCCCCCCCCCEEEECCCHHEEEHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCC
EAELHARVTVRIKEVTLDENKNRVETVKRVETTLGRALLSEILPPGLPFSFVDKALKKKE
CCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ISKLINASFRRCGLRETVIFADKLMYTGFTFATRAGMSIAIKDMLIPQEKGQILGAAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCEEEEHHHHCCCCCCCEEECCHHH
VKEIESQYTSGLVTQGERYNKVVDIWGRAGDAVAKAMMGQLGGEKVTDRQGKEVTQESFN
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
AIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNMLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTKNGLLVKALVEGGEVVEALRERIL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHH
GRVAASDIINPETQETVFEAGTLLSEDVVDTIEALGIDEVRVRTPLTCETRYGLCANCYG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEECCCCCCCHHHHC
RDLGRGYLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQLEAKSNGAVQY
CCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEE
TATMRYVTNARKELVAISRSGEILIADDSGRERERHKVPYGATLMVTDGAKIKAGAVLAT
EEHHHHHHHHHHHHEEEECCCCEEEECCCCCCHHHHCCCCCEEEEEECCCEEECCEEEEE
WDPHTRPIITEYAGRVRFENVEEGVTVAKQVDDVTGLSTLVVIDPKRKSTSTKGVRPQVK
CCCCCCCHHHHHCCCCEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEE
LLDDAGNELKIAGTDTLVNITFQIGSIITVKDGQDVAVGDVLARIPQETSKTRDITGGLP
EECCCCCEEEEECCCEEEEEEEEECCEEEEECCCCCHHHHHHHHCCHHHCCCCCCCCCCH
RVAELFEARSPKDAGVLAEVTGTVSFGKDTKGKQRLVITDLDGVAHEYLITKEKHVTAHD
HHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCHHHHHHEECCCEEECCC
GQIVQKGEMIVDGPVDPHDILRLQGVEALASYITDEVQDVYRLQGVKINDKHIEVIVRQM
CCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRRVVVADPGDTGLIPGEQVERSEVLQINDEMIAAGKEPAVYDPILLGITKASLSTDSFI
HHHHEEECCCCCCCCCCCCCCCHHHEEECCHHHCCCCCCCCCCHHHEEEEHHCCCCHHHH
SAASFQETTRVLTEAAIMGKKDELRGLKENVIVGRLIPAGSGLAYHNTRRRQAAGEDMGA
HHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCEEEEEECCCCCCEECCCHHHHHCCCCCCH
DRLLEGGETPAAENQEVA
HHHHCCCCCCCCCCCCCC
>Mature Secondary Structure
MKALLDLFKQATHEEEFDAIKIGLASPDKIRSWSYGEVKKPETINYRTFKPERDGLFCAK
CHHHHHHHHHHCCCCCCCEEEEECCCCHHHCCCCCCCCCCCCCCCEEECCCCCCCEEEEH
IFGPVKDYECLCGKYKRLKHRGVICEKCGVEVTLSKVRRERMGHIELASPVAHIWFLKSL
HHCCCCHHHHHHHHHHHHHHCCCCHHHCCCCHHHHHHHHHHCCCEEHHHHHHHHHHHHHH
PSRLGMVLDMTLRDIERVLYFEGFVVVEPGMTPLNRGQLLTEEDYLGKLEEYGDEFKALM
HHHHHHHHHHHHHHHHHHHHHCCEEEECCCCCCCCCCCEECCHHHHHHHHHHHHHHHHHH
GAEGVRELLRSLDVASEVETLHSEISKTGSDTKLKKLSKRLKILEGFQKSGIKPEWMILE
CHHHHHHHHHHCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCEEEEE
VLPVLPPELRPLVPLDGGRFATSDLNDLYRRVINRNNRLKRLLELKAPEIIVRNEKRMLQ
HHHCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCHHHHHHHHHCCCCEEECCHHHHHH
EAVDSLLDNGRRGKAMTGANKRPLKSLADMIKGKSGRFRQNLLGKRVDYSGRSVIVVGPT
HHHHHHHCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCHHHHHHCCCCCCCCCEEEEECCC
LKLHQCGLPKKMALELFKPFIFNRLEVLGLATTIKAAKKMVEDEEPIVWDLLEEVIREHP
EEEHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHHCC
VMLNRAPTLHRLGIQAFEPVLIEGKAIQLHPLVCAAFNADFDGDQMAVHVPLSLEAQAEA
EEECCCCCHHHHCHHHCCCEEECCCEEEECCEEEEEECCCCCCCCEEEEECCCCCCCCCC
RTLMLASNNVLSPANGEPIIVPSQDIVLGLYYMTREKVNAKGEGMMFADVTEARRAYDNR
EEEEEECCCCCCCCCCCEEEECCCHHEEEHHHHHHHHCCCCCCCEEEEHHHHHHHHHCCC
EAELHARVTVRIKEVTLDENKNRVETVKRVETTLGRALLSEILPPGLPFSFVDKALKKKE
CCEEEEEEEEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHHHHH
ISKLINASFRRCGLRETVIFADKLMYTGFTFATRAGMSIAIKDMLIPQEKGQILGAAEAE
HHHHHHHHHHHCCCCHHHHHHHHHHHCCCHHHHHCCCEEEEHHHHCCCCCCCEEECCHHH
VKEIESQYTSGLVTQGERYNKVVDIWGRAGDAVAKAMMGQLGGEKVTDRQGKEVTQESFN
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCHHHHHHHHHHHCCCCCCCCCCCHHHHHHCCC
AIYMMADSGARGSAAQIRQLAGMRGLMAKPDGSIIETPITANFREGLNMLQYFISTHGAR
EEEEEECCCCCCCHHHHHHHHCCCCCCCCCCCCEEECCCCCCHHHHHHHHHHHHHHCCCC
KGLADTALKTANSGYLTRRLVDVTQDLVVTEDDCGTKNGLLVKALVEGGEVVEALRERIL
CCHHHHHHHHCCCCHHHHHHHHHHHHHEEECCCCCCCCCEEEEEECCCHHHHHHHHHHHH
GRVAASDIINPETQETVFEAGTLLSEDVVDTIEALGIDEVRVRTPLTCETRYGLCANCYG
HHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCEECCCCCCCHHHHC
RDLGRGYLVNVGEAVGVIAAQSIGEPGTQLTMRTFHIGGAASRAAAASQLEAKSNGAVQY
CCCCCCEEEECCHHHHHHHHHHCCCCCCEEEEEEEEECCCHHHHHHHHHHHHCCCCCEEE
TATMRYVTNARKELVAISRSGEILIADDSGRERERHKVPYGATLMVTDGAKIKAGAVLAT
EEHHHHHHHHHHHHEEEECCCCEEEECCCCCCHHHHCCCCCEEEEEECCCEEECCEEEEE
WDPHTRPIITEYAGRVRFENVEEGVTVAKQVDDVTGLSTLVVIDPKRKSTSTKGVRPQVK
CCCCCCCHHHHHCCCCEECCHHHHHHHHHHHHHHCCCEEEEEECCCCCCCCCCCCCCCEE
LLDDAGNELKIAGTDTLVNITFQIGSIITVKDGQDVAVGDVLARIPQETSKTRDITGGLP
EECCCCCEEEEECCCEEEEEEEEECCEEEEECCCCCHHHHHHHHCCHHHCCCCCCCCCCH
RVAELFEARSPKDAGVLAEVTGTVSFGKDTKGKQRLVITDLDGVAHEYLITKEKHVTAHD
HHHHHHHCCCCCCCCEEEEEEEEEECCCCCCCCCEEEEEECCCHHHHHHEECCCEEECCC
GQIVQKGEMIVDGPVDPHDILRLQGVEALASYITDEVQDVYRLQGVKINDKHIEVIVRQM
CCEEECCCEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEECHHHHHHHHHHH
LRRVVVADPGDTGLIPGEQVERSEVLQINDEMIAAGKEPAVYDPILLGITKASLSTDSFI
HHHHEEECCCCCCCCCCCCCCCHHHEEECCHHHCCCCCCCCCCHHHEEEEHHCCCCHHHH
SAASFQETTRVLTEAAIMGKKDELRGLKENVIVGRLIPAGSGLAYHNTRRRQAAGEDMGA
HHHHHHHHHHHHHHHHHCCCHHHHCCHHHCCEEEEEECCCCCCEECCCHHHHHCCCCCCH
DRLLEGGETPAAENQEVA
HHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA