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The map label for this gene is rpoB

Identifier: 74316416

GI number: 74316416

Start: 424459

End: 428538

Strand: Direct

Name: rpoB

Synonym: Tbd_0398

Alternate gene names: 74316416

Gene position: 424459-428538 (Clockwise)

Preceding gene: 74316415

Following gene: 74316417

Centisome position: 14.59

GC content: 63.41

Gene sequence:

>4080_bases
ATGGCTTATACCTTTACCGAGAAAAAACGTCTGCGCAAGAGTTTTGCCAGCCGGACCAACACGCTTCCGGTGCCTTTTCT
TCTGGCGACCCAGCTTGAGTCCTATCGGGCTTTCCTGCAGGAGGGCCGTTCGCGCGACGAGCGCCTGAACGAGGGCCTGC
AAGCCGCGTTCACATCGATTTTCCCGATCGAAAGCCATTCCAAGAACGCCAGGCTCGAATACGTCAGCTATCAACTCGGC
GAGCCGGTCTTCGACATCAAGGAATGCCAGCAGCGCGGCCTCACCTATTGTGCGCCGCTGCGCGCCAAGGTGCGCCTGGT
CATCATGGACAAGGAGGCGTCCAAGCCGACGATCAAGGAGGTCAAGGAGCAGGAGGTCTACATGGGCGAGATTCCGCTCA
TGACGCCGACCGGCTCGTTCGTCATCAACGGCACCGAGCGCGTCATCGTGTCGCAGCTGCACCGCTCGCCGGGCGTATTC
TTCGAGCACGACCGCGGCAAGACGCACAGCTCGGGGAAGCTCTTGTTCTCGGCGCGCGTCATTCCCTACCGCGGCTCGTG
GCTCGACTTCGAGTTTGACGCCAAGGACATCCTGTTCTTCCGCGTCGACCGTCGCCGCAAGATGCCGGTCACGATCCTGC
TCAAGGCGCTCGGCTACACGCCGGAGAGCATTCTGGACGCGTTCTTCAATAAGGACACGTTCTACATCAACACCCTCGGC
ATCCAGTTCGAGCTCGTTCCCGAGCGGCTGCGCGGCGAGATCGCGCGTTTCGACATCTGCGGCAAGGACGACAAGGTCAT
CGTCGCCAAGGACAAGCGCATCACGGCCAAGCACATCCGTGAACTCGACGCCGCCGGCGTCAAGAAATGGGCCGTGCCGG
GCGAATTCGTCGTCGGCCGCGTGCTCGCGCACGACGTCGTCGACAAGGACACGGGCGAGCTCGTCGCGCGCGCCAACGAC
GAAATCACCGAGGAGTTGCTGAAGAAGCTGGCGGCCGCCGGCATCGACAAGTTCCAGACCCTCTACACCAACGACCTCGA
CCACGGCGCATTCATCTCGCAGACGCTGCGTACCGACGACACGACCGACGAGTATGCCGCCAAGGTCGCGATCTACCGCA
TGATGCGCCCGGGCGAGCCGCCGACCGAGGACGCCGTCAACGCGTTGTTCGTCAACCTGTTCTTCAGCGACGAGCGCTAC
GATCTGTCGGCCGTCGGGCGCATGAAGTTCAACCGCCGCATCGGCCGCGACGAGCTGACCGGAACCGGCACGCTGTCGAC
CGAAGACATCGTGGCCGTGATCAAGATCCTGGTCGAACTGCGCAATGGCCGCGGCGAGATCGACGACATCGACCACCTCG
GCAACCGTCGCGTGCGCTCGGTCGGCGAACTCGCCGAGAACCAGTTCCGCGCCGGCCTCGTGCGCGTCGAGCGCGCGGTG
CGCGAGCGCCTGAGCCAGGCGGAATCGGACAACCTGATGCCGCACGATCTGATCAATGCCAAGCCCGTCTCGGCCGCGAT
CAAGGAGTTCTTCGGGTCGAGCCAGCTCTCGCAGTTCATGGACCAGACCAACCCCTTGTCCGAGATCACCCACAAGCGCC
GTGTCTCGGCGCTCGGCCCGGGCGGTCTGACCCGCGAGCGCGCCGGTTTCGAGGTGCGCGACGTGCACCCGACTCACTAT
GGCCGCGTCTGCCCGATCGAAACGCCGGAAGGTCCGAACATCGGTCTGATCAACTCGCTCGCGCTGTTCGCGCGCACCAA
CTGGTACGGCTTCATCGAGACGCCCTACCGCAAGGTCGTCGACAACAAGGTCACCGACGAAATCGAATACCTCTCGGCGA
TCGAGGAGTCCAAGTACGTGATCGCGCAGGCAAACGCCGAGCTCGACGCCAAGGGCAAGTTCAAGGACGACCTCGTGTCG
TGCCGGTTCAAGAACGAATTCACGCTGTCGGCCCCCGACCGCATCGAATACATGGACGTCGCGCCGGCACAGATCGTGTC
GGTGGCCGCCTCGCTGATCCCCTTCCTCGAGCATGACGACGCGAACCGCGCGCTCATGGGCTCGAACATGCAGCGGCAGG
CCGTGCCCTGCCTGCGTCCGGAAAAACCCTTCGTCGGGACCGGCATCGAGCGCACCGCCGCGGTCGACTCCGGTACCGTC
GTCATCGCCCACCGCGGCGGCCGCGTCGACTATGTGGACGCCGGGCGGATCGTGATCCGCGTGCACGACGAAGAGGCGCG
CGCGGGCGAGGTCGGCGTCGACATCTATTCGCTGATCAAGTACACGCGCTCGAACCAGAACACCAACATCAACCAGCGAC
CGCTGGTCAAAGTGGGCGACGTGATCGCACGCGGCGACGTCATTGCCGACGGCGCCTCGACCGACATGGGCGAGCTCGCG
CTGGGCCAGAACATGCTGGTCGCGTTCATGCCGTGGAACGGCTACAACTTCGAAGACTCGATCCTGATCAACGAGAAGGT
CGTCGCGGAAGACCGTTACACCTCGATCCACATCGAGGAACTGTCGGTCGTTGCGCGTGACACCAAGCTCGGGCCCGAAG
AAATCACGCGTGACATTTCCAACCTCGCCGAGCGCCAGCTCGCGCGGCTCGACGAGTCGGGCATCATCGCGATCGGTGCC
GAGGTCGAGGCGGGCGACGTGCTCGTCGGCAAGGTCACGCCCAAGGGCGAGACTCAGCTCACGCCGGAAGAGAAGCTCCT
GCGCGCAATCTTCGGCGAGAAGGCGTCCGACGTGAAGGACACGTCGCTCAAGGTGCCGTCGGGCATGTCCGGCGTCGTCA
TCGACGTTCAGGTCTTCACGCGCGAAGGCATTGAAAGGGATAAACGCGCCCAGTCGATCATCGACACCCAGCTCGCCGAG
TACAAGAAGGACCTGACCGACCGCATGCGCATCGTCGAGGACGACACCTTCGCGCGCCTCGAGAAGCTCCTGCATCTCAA
GGTCGTGAACGGCGGACCGAAGAAGCTCGCCAAGGGCAGCAAGATCAGCAAGGAATATCTCGATTCGCTCAATCGCCACG
ACTGGTTCGACATCCGGCTGGCCGACGACGAGGCGAGCCGTCAGGTCGAGTCGCTGAAGGACAGCCTGACGCAGAAACGC
GTCGAGTTCGACGCGATGTTCGAGGAGAAGAAGCAAAAGCTGACCGCGGGCGACGAGCTGCCGCCCGGCGTGCAGAAGAT
GGTCAAGGTCTATCTGGCGGTCAAGCGCCGCCTGCAGCCTGGCGACAAGATGGCCGGCCGTCACGGCAACAAGGGTGTCG
TGTCGAAGATCGTTCCGGTCGAGGACATGCCCTTCATGGCCGACGGCCGCCCGGTCGACATCGTGTTGAATCCGCTCGGC
GTGCCGTCGCGGATGAACATCGGCCAGATTCTCGAGACCCACCTTGGCTGGGCGTCGAAAGGGCTCGGCGAAAAGATCGG
CCAGATGATGGCCGCGCAGACTAAATCGGTGGTGAAGGAGTTGCGGCACTTCTTCAAGGAGGTCTACAACCAGTCGGGCA
AGGCGGAGGACATCGACAACTTTACCGACGACGAAATCCTCGAGCTCGGCCAGAACCTGCAAAAGGGCGTGCCCTTCGCC
TCGCCCGTGTTCGACGGCGCGACCGAAGAGGAGATTCGCCGCATGCTCGCGCTCGCCGGCCTGCCCGAGGGCGGCCAGGT
CACGCTCTACGACGGTCGCACCGGCGAAGCCTTCGACCGTCAGGTCACCGTCGGCTACAAGCATGTGCTGAAGCTGCACC
ACCTGGTCGACGACAAGATGCACGCGCGCTCGACCGGCCCGTACTCGCTCGTGACCCAGCAGCCGCTGGGCGGCAAGGCG
CAGTTCGGCGGCCAGCGCTTCGGCGAAATGGAAGTGTGGGCACTCGAGGCCTATGGTGCCTCCTACGTGCTGCAGGAAAT
GCTGACCGTGAAGTCCGACGACGTGAACGGCCGGACCAAGGTGTACGAGAACATCGTCAAGGGCGATCACAAGATCGAGG
CCGGCATGCCCGAGTCCTTCAACGTGCTGGTGAAGGAAATCCGAAGCCTGGGCATCGACATCGATCTGGAACGTTATTAA

Upstream 100 bases:

>100_bases
CCCGGACACGGCTTCCGGGTCGTTTGCTTTTTGCGTGTGCCTCACACTGAGCCGGCCGTAGCCGACGTGCCCGCCCGCCC
CTGATCGTCAAGGAGACCCC

Downstream 100 bases:

>100_bases
TTTTGGGGTGAGGACACAGCCATGAAAGCACTGTTGGATCTATTCAAGCAGGCCACCCACGAGGAAGAATTCGACGCCAT
CAAGATCGGCCTGGCGTCGC

Product: DNA-directed RNA polymerase subunit beta

Products: NA

Alternate protein names: RNAP subunit beta; RNA polymerase subunit beta; Transcriptase subunit beta

Number of amino acids: Translated: 1359; Mature: 1358

Protein sequence:

>1359_residues
MAYTFTEKKRLRKSFASRTNTLPVPFLLATQLESYRAFLQEGRSRDERLNEGLQAAFTSIFPIESHSKNARLEYVSYQLG
EPVFDIKECQQRGLTYCAPLRAKVRLVIMDKEASKPTIKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVF
FEHDRGKTHSSGKLLFSARVIPYRGSWLDFEFDAKDILFFRVDRRRKMPVTILLKALGYTPESILDAFFNKDTFYINTLG
IQFELVPERLRGEIARFDICGKDDKVIVAKDKRITAKHIRELDAAGVKKWAVPGEFVVGRVLAHDVVDKDTGELVARAND
EITEELLKKLAAAGIDKFQTLYTNDLDHGAFISQTLRTDDTTDEYAAKVAIYRMMRPGEPPTEDAVNALFVNLFFSDERY
DLSAVGRMKFNRRIGRDELTGTGTLSTEDIVAVIKILVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAV
RERLSQAESDNLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHY
GRVCPIETPEGPNIGLINSLALFARTNWYGFIETPYRKVVDNKVTDEIEYLSAIEESKYVIAQANAELDAKGKFKDDLVS
CRFKNEFTLSAPDRIEYMDVAPAQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPFVGTGIERTAAVDSGTV
VIAHRGGRVDYVDAGRIVIRVHDEEARAGEVGVDIYSLIKYTRSNQNTNINQRPLVKVGDVIARGDVIADGASTDMGELA
LGQNMLVAFMPWNGYNFEDSILINEKVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAERQLARLDESGIIAIGA
EVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLKVPSGMSGVVIDVQVFTREGIERDKRAQSIIDTQLAE
YKKDLTDRMRIVEDDTFARLEKLLHLKVVNGGPKKLAKGSKISKEYLDSLNRHDWFDIRLADDEASRQVESLKDSLTQKR
VEFDAMFEEKKQKLTAGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPFMADGRPVDIVLNPLG
VPSRMNIGQILETHLGWASKGLGEKIGQMMAAQTKSVVKELRHFFKEVYNQSGKAEDIDNFTDDEILELGQNLQKGVPFA
SPVFDGATEEEIRRMLALAGLPEGGQVTLYDGRTGEAFDRQVTVGYKHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKA
QFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGDHKIEAGMPESFNVLVKEIRSLGIDIDLERY

Sequences:

>Translated_1359_residues
MAYTFTEKKRLRKSFASRTNTLPVPFLLATQLESYRAFLQEGRSRDERLNEGLQAAFTSIFPIESHSKNARLEYVSYQLG
EPVFDIKECQQRGLTYCAPLRAKVRLVIMDKEASKPTIKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVF
FEHDRGKTHSSGKLLFSARVIPYRGSWLDFEFDAKDILFFRVDRRRKMPVTILLKALGYTPESILDAFFNKDTFYINTLG
IQFELVPERLRGEIARFDICGKDDKVIVAKDKRITAKHIRELDAAGVKKWAVPGEFVVGRVLAHDVVDKDTGELVARAND
EITEELLKKLAAAGIDKFQTLYTNDLDHGAFISQTLRTDDTTDEYAAKVAIYRMMRPGEPPTEDAVNALFVNLFFSDERY
DLSAVGRMKFNRRIGRDELTGTGTLSTEDIVAVIKILVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAV
RERLSQAESDNLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHY
GRVCPIETPEGPNIGLINSLALFARTNWYGFIETPYRKVVDNKVTDEIEYLSAIEESKYVIAQANAELDAKGKFKDDLVS
CRFKNEFTLSAPDRIEYMDVAPAQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPFVGTGIERTAAVDSGTV
VIAHRGGRVDYVDAGRIVIRVHDEEARAGEVGVDIYSLIKYTRSNQNTNINQRPLVKVGDVIARGDVIADGASTDMGELA
LGQNMLVAFMPWNGYNFEDSILINEKVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAERQLARLDESGIIAIGA
EVEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLKVPSGMSGVVIDVQVFTREGIERDKRAQSIIDTQLAE
YKKDLTDRMRIVEDDTFARLEKLLHLKVVNGGPKKLAKGSKISKEYLDSLNRHDWFDIRLADDEASRQVESLKDSLTQKR
VEFDAMFEEKKQKLTAGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPFMADGRPVDIVLNPLG
VPSRMNIGQILETHLGWASKGLGEKIGQMMAAQTKSVVKELRHFFKEVYNQSGKAEDIDNFTDDEILELGQNLQKGVPFA
SPVFDGATEEEIRRMLALAGLPEGGQVTLYDGRTGEAFDRQVTVGYKHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKA
QFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGDHKIEAGMPESFNVLVKEIRSLGIDIDLERY
>Mature_1358_residues
AYTFTEKKRLRKSFASRTNTLPVPFLLATQLESYRAFLQEGRSRDERLNEGLQAAFTSIFPIESHSKNARLEYVSYQLGE
PVFDIKECQQRGLTYCAPLRAKVRLVIMDKEASKPTIKEVKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFF
EHDRGKTHSSGKLLFSARVIPYRGSWLDFEFDAKDILFFRVDRRRKMPVTILLKALGYTPESILDAFFNKDTFYINTLGI
QFELVPERLRGEIARFDICGKDDKVIVAKDKRITAKHIRELDAAGVKKWAVPGEFVVGRVLAHDVVDKDTGELVARANDE
ITEELLKKLAAAGIDKFQTLYTNDLDHGAFISQTLRTDDTTDEYAAKVAIYRMMRPGEPPTEDAVNALFVNLFFSDERYD
LSAVGRMKFNRRIGRDELTGTGTLSTEDIVAVIKILVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAVR
ERLSQAESDNLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGPGGLTRERAGFEVRDVHPTHYG
RVCPIETPEGPNIGLINSLALFARTNWYGFIETPYRKVVDNKVTDEIEYLSAIEESKYVIAQANAELDAKGKFKDDLVSC
RFKNEFTLSAPDRIEYMDVAPAQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPFVGTGIERTAAVDSGTVV
IAHRGGRVDYVDAGRIVIRVHDEEARAGEVGVDIYSLIKYTRSNQNTNINQRPLVKVGDVIARGDVIADGASTDMGELAL
GQNMLVAFMPWNGYNFEDSILINEKVVAEDRYTSIHIEELSVVARDTKLGPEEITRDISNLAERQLARLDESGIIAIGAE
VEAGDVLVGKVTPKGETQLTPEEKLLRAIFGEKASDVKDTSLKVPSGMSGVVIDVQVFTREGIERDKRAQSIIDTQLAEY
KKDLTDRMRIVEDDTFARLEKLLHLKVVNGGPKKLAKGSKISKEYLDSLNRHDWFDIRLADDEASRQVESLKDSLTQKRV
EFDAMFEEKKQKLTAGDELPPGVQKMVKVYLAVKRRLQPGDKMAGRHGNKGVVSKIVPVEDMPFMADGRPVDIVLNPLGV
PSRMNIGQILETHLGWASKGLGEKIGQMMAAQTKSVVKELRHFFKEVYNQSGKAEDIDNFTDDEILELGQNLQKGVPFAS
PVFDGATEEEIRRMLALAGLPEGGQVTLYDGRTGEAFDRQVTVGYKHVLKLHHLVDDKMHARSTGPYSLVTQQPLGGKAQ
FGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTKVYENIVKGDHKIEAGMPESFNVLVKEIRSLGIDIDLERY

Specific function: DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates

COG id: COG0085

COG function: function code K; DNA-directed RNA polymerase, beta subunit/140 kD subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the RNA polymerase beta chain family

Homologues:

Organism=Homo sapiens, GI238908503, Length=296, Percent_Identity=30.7432432432432, Blast_Score=124, Evalue=5e-28,
Organism=Homo sapiens, GI238908505, Length=296, Percent_Identity=30.7432432432432, Blast_Score=124, Evalue=6e-28,
Organism=Homo sapiens, GI4505941, Length=303, Percent_Identity=30.03300330033, Blast_Score=124, Evalue=7e-28,
Organism=Homo sapiens, GI212286172, Length=251, Percent_Identity=32.6693227091633, Blast_Score=120, Evalue=8e-27,
Organism=Homo sapiens, GI33469941, Length=251, Percent_Identity=32.6693227091633, Blast_Score=120, Evalue=8e-27,
Organism=Escherichia coli, GI1790419, Length=1360, Percent_Identity=66.3235294117647, Blast_Score=1875, Evalue=0.0,
Organism=Caenorhabditis elegans, GI17552304, Length=304, Percent_Identity=29.9342105263158, Blast_Score=124, Evalue=3e-28,
Organism=Caenorhabditis elegans, GI25144348, Length=305, Percent_Identity=31.1475409836066, Blast_Score=121, Evalue=3e-27,
Organism=Caenorhabditis elegans, GI17506623, Length=233, Percent_Identity=33.4763948497854, Blast_Score=118, Evalue=2e-26,
Organism=Saccharomyces cerevisiae, GI6324781, Length=304, Percent_Identity=32.5657894736842, Blast_Score=132, Evalue=3e-31,
Organism=Saccharomyces cerevisiae, GI6324725, Length=248, Percent_Identity=32.258064516129, Blast_Score=122, Evalue=5e-28,
Organism=Saccharomyces cerevisiae, GI6325267, Length=248, Percent_Identity=31.8548387096774, Blast_Score=115, Evalue=6e-26,
Organism=Drosophila melanogaster, GI17647877, Length=306, Percent_Identity=30.718954248366, Blast_Score=118, Evalue=3e-26,
Organism=Drosophila melanogaster, GI17136444, Length=248, Percent_Identity=31.8548387096774, Blast_Score=114, Evalue=3e-25,
Organism=Drosophila melanogaster, GI17136446, Length=252, Percent_Identity=32.1428571428571, Blast_Score=110, Evalue=8e-24,

Paralogues:

None

Copy number: 4233 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. 2,500 Molecules/Cell In: Glucose minimal media [C]

Swissprot (AC and ID): RPOB_THIDA (Q3SLQ6)

Other databases:

- EMBL:   CP000116
- RefSeq:   YP_314156.1
- ProteinModelPortal:   Q3SLQ6
- STRING:   Q3SLQ6
- GeneID:   3671665
- GenomeReviews:   CP000116_GR
- KEGG:   tbd:Tbd_0398
- NMPDR:   fig|292415.3.peg.851
- eggNOG:   COG0085
- HOGENOM:   HBG285547
- OMA:   QRDLTYA
- PhylomeDB:   Q3SLQ6
- BioCyc:   TDEN292415:TBD_0398-MONOMER
- HAMAP:   MF_01321
- InterPro:   IPR010243
- InterPro:   IPR019462
- InterPro:   IPR015712
- InterPro:   IPR007120
- InterPro:   IPR007121
- InterPro:   IPR007644
- InterPro:   IPR007642
- InterPro:   IPR007645
- InterPro:   IPR007641
- InterPro:   IPR014724
- Gene3D:   G3DSA:2.40.50.150
- PANTHER:   PTHR20856
- TIGRFAMs:   TIGR02013

Pfam domain/function: PF04563 RNA_pol_Rpb2_1; PF04561 RNA_pol_Rpb2_2; PF04565 RNA_pol_Rpb2_3; PF10385 RNA_pol_Rpb2_45; PF00562 RNA_pol_Rpb2_6; PF04560 RNA_pol_Rpb2_7

EC number: =2.7.7.6

Molecular weight: Translated: 152060; Mature: 151929

Theoretical pI: Translated: 6.12; Mature: 6.12

Prosite motif: PS01166 RNA_POL_BETA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAYTFTEKKRLRKSFASRTNTLPVPFLLATQLESYRAFLQEGRSRDERLNEGLQAAFTSI
CCCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FPIESHSKNARLEYVSYQLGEPVFDIKECQQRGLTYCAPLRAKVRLVIMDKEASKPTIKE
CCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHCCCEEEECCCEEEEEEEEECCCCCCHHHH
VKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARV
HHHHHHEECCCCEECCCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEE
IPYRGSWLDFEFDAKDILFFRVDRRRKMPVTILLKALGYTPESILDAFFNKDTFYINTLG
EEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEE
IQFELVPERLRGEIARFDICGKDDKVIVAKDKRITAKHIRELDAAGVKKWAVPGEFVVGR
EEEEECCHHHCCCHHEEEECCCCCCEEEECCCCCHHHHHHHHHHCCCHHCCCCHHHHHHH
VLAHDVVDKDTGELVARANDEITEELLKKLAAAGIDKFQTLYTNDLDHGAFISQTLRTDD
HHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCC
TTDEYAAKVAIYRMMRPGEPPTEDAVNALFVNLFFSDERYDLSAVGRMKFNRRIGRDELT
CHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
GTGTLSTEDIVAVIKILVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RERLSQAESDNLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGP
HHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALFARTNWYGFIETPYRKVV
CCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHH
DNKVTDEIEYLSAIEESKYVIAQANAELDAKGKFKDDLVSCRFKNEFTLSAPDRIEYMDV
CCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHEEEECCCEEECCCCCCEEECC
APAQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPFVGTGIERTAAVDSGTV
CHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCHHEECCCCEE
VIAHRGGRVDYVDAGRIVIRVHDEEARAGEVGVDIYSLIKYTRSNQNTNINQRPLVKVGD
EEEECCCEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VIARGDVIADGASTDMGELALGQNMLVAFMPWNGYNFEDSILINEKVVAEDRYTSIHIEE
HHHCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEECCEEECCCCCCEEEHHH
LSVVARDTKLGPEEITRDISNLAERQLARLDESGIIAIGAEVEAGDVLVGKVTPKGETQL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCC
TPEEKLLRAIFGEKASDVKDTSLKVPSGMSGVVIDVQVFTREGIERDKRAQSIIDTQLAE
CHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHH
YKKDLTDRMRIVEDDTFARLEKLLHLKVVNGGPKKLAKGSKISKEYLDSLNRHDWFDIRL
HHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCHHHHHCCCCCHHHHHHCCCCCCEEEEEE
ADDEASRQVESLKDSLTQKRVEFDAMFEEKKQKLTAGDELPPGVQKMVKVYLAVKRRLQP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
GDKMAGRHGNKGVVSKIVPVEDMPFMADGRPVDIVLNPLGVPSRMNIGQILETHLGWASK
CHHHCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHC
GLGEKIGQMMAAQTKSVVKELRHFFKEVYNQSGKAEDIDNFTDDEILELGQNLQKGVPFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SPVFDGATEEEIRRMLALAGLPEGGQVTLYDGRTGEAFDRQVTVGYKHVLKLHHLVDDKM
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHH
HARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTK
HHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHH
VYENIVKGDHKIEAGMPESFNVLVKEIRSLGIDIDLERY
HHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEEECCC
>Mature Secondary Structure 
AYTFTEKKRLRKSFASRTNTLPVPFLLATQLESYRAFLQEGRSRDERLNEGLQAAFTSI
CCCCHHHHHHHHHHHHCCCCCCCHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHH
FPIESHSKNARLEYVSYQLGEPVFDIKECQQRGLTYCAPLRAKVRLVIMDKEASKPTIKE
CCCCCCCCCCEEEEEEHHHCCCCHHHHHHHHCCCEEEECCCEEEEEEEEECCCCCCHHHH
VKEQEVYMGEIPLMTPTGSFVINGTERVIVSQLHRSPGVFFEHDRGKTHSSGKLLFSARV
HHHHHHEECCCCEECCCCCEEECCHHHHHHHHHHCCCCCEEECCCCCCCCCCCEEEEEEE
IPYRGSWLDFEFDAKDILFFRVDRRRKMPVTILLKALGYTPESILDAFFNKDTFYINTLG
EEECCCEEEEEECCCEEEEEEECCCCCCCHHHHHHHHCCCHHHHHHHHHCCCEEEEEEEE
IQFELVPERLRGEIARFDICGKDDKVIVAKDKRITAKHIRELDAAGVKKWAVPGEFVVGR
EEEEECCHHHCCCHHEEEECCCCCCEEEECCCCCHHHHHHHHHHCCCHHCCCCHHHHHHH
VLAHDVVDKDTGELVARANDEITEELLKKLAAAGIDKFQTLYTNDLDHGAFISQTLRTDD
HHHHHHHCCCCHHHHHHCCHHHHHHHHHHHHHCCHHHHHHHHCCCCCCCHHHHHHHCCCC
TTDEYAAKVAIYRMMRPGEPPTEDAVNALFVNLFFSDERYDLSAVGRMKFNRRIGRDELT
CHHHHHHHHHHHHHHCCCCCCHHHHHHHEEEEEEECCCCCCHHHHHHHHHHHCCCCCCCC
GTGTLSTEDIVAVIKILVELRNGRGEIDDIDHLGNRRVRSVGELAENQFRAGLVRVERAV
CCCCCCHHHHHHHHHHHHHHHCCCCCCCHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHH
RERLSQAESDNLMPHDLINAKPVSAAIKEFFGSSQLSQFMDQTNPLSEITHKRRVSALGP
HHHHHHHCCCCCCCHHHCCCCHHHHHHHHHHCHHHHHHHHHCCCCHHHHHHHHHHHCCCC
GGLTRERAGFEVRDVHPTHYGRVCPIETPEGPNIGLINSLALFARTNWYGFIETPYRKVV
CCCCHHHCCCEEEECCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEECCHHHHHH
DNKVTDEIEYLSAIEESKYVIAQANAELDAKGKFKDDLVSCRFKNEFTLSAPDRIEYMDV
CCHHHHHHHHHHHHHHCCEEEEECCCCCCCCCCCHHHHHEEEECCCEEECCCCCCEEECC
APAQIVSVAASLIPFLEHDDANRALMGSNMQRQAVPCLRPEKPFVGTGIERTAAVDSGTV
CHHHHHHHHHHHHHHHCCCCCCCHHHCCCCHHHCCCCCCCCCCCCCCCCCHHEECCCCEE
VIAHRGGRVDYVDAGRIVIRVHDEEARAGEVGVDIYSLIKYTRSNQNTNINQRPLVKVGD
EEEECCCEEEEEECCEEEEEEECCCCCCCCCCHHHHHHHHHHHCCCCCCCCCCCCHHHHH
VIARGDVIADGASTDMGELALGQNMLVAFMPWNGYNFEDSILINEKVVAEDRYTSIHIEE
HHHCCCEEECCCCCCCHHHHCCCCEEEEEECCCCCCCCCCEEECCEEECCCCCCEEEHHH
LSVVARDTKLGPEEITRDISNLAERQLARLDESGIIAIGAEVEAGDVLVGKVTPKGETQL
HHHHHHCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEEEECCCCCCCEEEEECCCCCCCCC
TPEEKLLRAIFGEKASDVKDTSLKVPSGMSGVVIDVQVFTREGIERDKRAQSIIDTQLAE
CHHHHHHHHHHCCCCCCCCCCCEECCCCCCCEEEEEEEHHHHCCCHHHHHHHHHHHHHHH
YKKDLTDRMRIVEDDTFARLEKLLHLKVVNGGPKKLAKGSKISKEYLDSLNRHDWFDIRL
HHHHHHHHHHHHCCHHHHHHHHHHEEEEECCCHHHHHCCCCCHHHHHHCCCCCCEEEEEE
ADDEASRQVESLKDSLTQKRVEFDAMFEEKKQKLTAGDELPPGVQKMVKVYLAVKRRLQP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHHHHCCC
GDKMAGRHGNKGVVSKIVPVEDMPFMADGRPVDIVLNPLGVPSRMNIGQILETHLGWASK
CHHHCCCCCCCCCHHCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCHHHHHHHHHCHHHC
GLGEKIGQMMAAQTKSVVKELRHFFKEVYNQSGKAEDIDNFTDDEILELGQNLQKGVPFA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHHHHHHHHHCCCCC
SPVFDGATEEEIRRMLALAGLPEGGQVTLYDGRTGEAFDRQVTVGYKHVLKLHHLVDDKM
CCCCCCCCHHHHHHHHHHHCCCCCCEEEEEECCCCCCCCCEEHHHHHHHHHHHHHHHHHH
HARSTGPYSLVTQQPLGGKAQFGGQRFGEMEVWALEAYGASYVLQEMLTVKSDDVNGRTK
HHCCCCCEEEEECCCCCCCCCCCCCCCCCEEEEEEECCCHHHHHHHHHHHCCCCCCCHHH
VYENIVKGDHKIEAGMPESFNVLVKEIRSLGIDIDLERY
HHHHHHCCCCEECCCCCHHHHHHHHHHHHCCCCEEECCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA