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The map label for this gene is ctaC [H]

Identifier: 74316343

GI number: 74316343

Start: 348068

End: 349216

Strand: Direct

Name: ctaC [H]

Synonym: Tbd_0325

Alternate gene names: 74316343

Gene position: 348068-349216 (Clockwise)

Preceding gene: 74316342

Following gene: 74316344

Centisome position: 11.96

GC content: 65.01

Gene sequence:

>1149_bases
ATGAAAAGCACGTGGCGATGGACAAGCGGGACCGCTGTGGGGCTGCTGACGCAGCCTGCGCTGGCGGAGTACGGTTATAA
CCTGCAGCAGCCGGCCAGTCAGGTGGCCCATGACGTCTTCCAGCTGCACAACCTGATCATGCTGGTGTGCGCGGGAATCT
TCGTCGTCGTGTTCGGCGCGATGTTCTACGCCCTGATCAAGCATCGCAAATCGGCCGGCCATCCCGCCGCGCATTTTCAC
GAGAACACCACGGTCGAAATCATCTGGACCGTGATCCCGTTCATCATCCTGATGGGTATGGCCTATCCGGCGGCCAAGGT
CGTGATCGACATGAAGGACACGTCGAACCCCGACCTCACAATCAAGGTCACCGGTTACCAGTGGAAGTGGGGCTACGACT
ACCTCAACGAGGACATCAGTTTCTACAGCACCCTCGCCACGCCGCGGGCCCAAATCACCGGCGCCGCGCCCAAGGGCGAA
AACTATCTGCTCGAAGTCGACGAGCCCGTCGTGGTGCCGGTCGGCAAGCGCGTGCGCATGCTGATCACCGCCAACGACGT
GTTGCACGCGTGGTGGGTGCCCGCGCTGGGCGCCAAGCAGGACGCGATTCCGGGGTTCATCCGCGACATCTGGTTCAAGG
CCGACGCGGTCGGAACGTATCGCGGGCAGTGCGTCGAGCTCTGCGGCAAGGACCACGGTTTCATGCCGATCGTCGTCGAG
GTCGTGTCGCAGGCCGACTACGAGGCCTGGGTCGCCGGCAAGAAGAGCGCCGCGAAGCGCGCCGAGGCCGACAACACGCG
TGAGTTCAGCGTCGCCGAACTGGTCGAGCGCGGCCAGAAGGTCTACGAAAGCAACTGCGCCGCCTGTCACCAGGCCGACG
GCAAGGGGCTCGCGGGTTCGTTTCCCGCGATCAGCGGCTCGAAAGTCGCCACCGGCCCCATCGCCGACCACATTGCGCTC
GTGCTGAATGGAAGACCGGGCACGGCCATGGCCGCTTTTGCGAAGCAGCTGTCCGACGCCGACATCGCGGCCGTCGTCAC
CTACCAGCGCAACGCGTGGGACAACAAGACCGGCGATCGGGTGCAGCCGGCCGACATCGCGAGCGCACGGGGCGGGGCCA
AGGTCGCCGCCGCGTCCGCCGCACAGTGA

Upstream 100 bases:

>100_bases
GCTCCGGCTGGCCGCGACGTTACGCAGCAAGTTGCAGGCATAGGTTGGCAACGGCGCCCGCAACGACTACCCATAACAAT
GTGAAGAGGATGGGGACGCG

Downstream 100 bases:

>100_bases
CCATCCAGGGGAGAGCCGAGAATGTCTGACGCAGTCCACGCCCACGAAGACCACGGACACCACGCGCACCCGAGCGGGAT
CATGCGCTGGCTGACGACCA

Product: cytochrome c oxidase subunit II

Products: NA

Alternate protein names: Cytochrome aa3 subunit 2; Cytochrome c oxidase polypeptide II; Oxidase aa(3) subunit 2 [H]

Number of amino acids: Translated: 382; Mature: 382

Protein sequence:

>382_residues
MKSTWRWTSGTAVGLLTQPALAEYGYNLQQPASQVAHDVFQLHNLIMLVCAGIFVVVFGAMFYALIKHRKSAGHPAAHFH
ENTTVEIIWTVIPFIILMGMAYPAAKVVIDMKDTSNPDLTIKVTGYQWKWGYDYLNEDISFYSTLATPRAQITGAAPKGE
NYLLEVDEPVVVPVGKRVRMLITANDVLHAWWVPALGAKQDAIPGFIRDIWFKADAVGTYRGQCVELCGKDHGFMPIVVE
VVSQADYEAWVAGKKSAAKRAEADNTREFSVAELVERGQKVYESNCAACHQADGKGLAGSFPAISGSKVATGPIADHIAL
VLNGRPGTAMAAFAKQLSDADIAAVVTYQRNAWDNKTGDRVQPADIASARGGAKVAAASAAQ

Sequences:

>Translated_382_residues
MKSTWRWTSGTAVGLLTQPALAEYGYNLQQPASQVAHDVFQLHNLIMLVCAGIFVVVFGAMFYALIKHRKSAGHPAAHFH
ENTTVEIIWTVIPFIILMGMAYPAAKVVIDMKDTSNPDLTIKVTGYQWKWGYDYLNEDISFYSTLATPRAQITGAAPKGE
NYLLEVDEPVVVPVGKRVRMLITANDVLHAWWVPALGAKQDAIPGFIRDIWFKADAVGTYRGQCVELCGKDHGFMPIVVE
VVSQADYEAWVAGKKSAAKRAEADNTREFSVAELVERGQKVYESNCAACHQADGKGLAGSFPAISGSKVATGPIADHIAL
VLNGRPGTAMAAFAKQLSDADIAAVVTYQRNAWDNKTGDRVQPADIASARGGAKVAAASAAQ
>Mature_382_residues
MKSTWRWTSGTAVGLLTQPALAEYGYNLQQPASQVAHDVFQLHNLIMLVCAGIFVVVFGAMFYALIKHRKSAGHPAAHFH
ENTTVEIIWTVIPFIILMGMAYPAAKVVIDMKDTSNPDLTIKVTGYQWKWGYDYLNEDISFYSTLATPRAQITGAAPKGE
NYLLEVDEPVVVPVGKRVRMLITANDVLHAWWVPALGAKQDAIPGFIRDIWFKADAVGTYRGQCVELCGKDHGFMPIVVE
VVSQADYEAWVAGKKSAAKRAEADNTREFSVAELVERGQKVYESNCAACHQADGKGLAGSFPAISGSKVATGPIADHIAL
VLNGRPGTAMAAFAKQLSDADIAAVVTYQRNAWDNKTGDRVQPADIASARGGAKVAAASAAQ

Specific function: Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B) [H]

COG id: COG1622

COG function: function code C; Heme/copper-type cytochrome/quinol oxidases, subunit 2

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the cytochrome c oxidase subunit 2 family [H]

Homologues:

Organism=Homo sapiens, GI251831110, Length=221, Percent_Identity=33.0316742081448, Blast_Score=140, Evalue=1e-33,
Organism=Saccharomyces cerevisiae, GI6226540, Length=234, Percent_Identity=30.7692307692308, Blast_Score=122, Evalue=7e-29,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001505
- InterPro:   IPR008972
- InterPro:   IPR014222
- InterPro:   IPR015964
- InterPro:   IPR002429
- InterPro:   IPR011759 [H]

Pfam domain/function: PF00116 COX2; PF02790 COX2_TM [H]

EC number: =1.9.3.1 [H]

Molecular weight: Translated: 41283; Mature: 41283

Theoretical pI: Translated: 7.30; Mature: 7.30

Prosite motif: PS00078 COX2 ; PS50999 COX2_TM ; PS50857 COX2_CUA ; PS51007 CYTC

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKSTWRWTSGTAVGLLTQPALAEYGYNLQQPASQVAHDVFQLHNLIMLVCAGIFVVVFGA
CCCCEEECCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFYALIKHRKSAGHPAAHFHENTTVEIIWTVIPFIILMGMAYPAAKVVIDMKDTSNPDLT
HHHHHHHHHHCCCCCHHHHCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
IKVTGYQWKWGYDYLNEDISFYSTLATPRAQITGAAPKGENYLLEVDEPVVVPVGKRVRM
EEEECEEEECCHHHHCCHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCEEEECCCCEEE
LITANDVLHAWWVPALGAKQDAIPGFIRDIWFKADAVGTYRGQCVELCGKDHGFMPIVVE
EEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHH
VVSQADYEAWVAGKKSAAKRAEADNTREFSVAELVERGQKVYESNCAACHQADGKGLAGS
HHHHCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
FPAISGSKVATGPIADHIALVLNGRPGTAMAAFAKQLSDADIAAVVTYQRNAWDNKTGDR
CCCCCCCCEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
VQPADIASARGGAKVAAASAAQ
CCCHHHHCCCCCCEECCCCCCC
>Mature Secondary Structure
MKSTWRWTSGTAVGLLTQPALAEYGYNLQQPASQVAHDVFQLHNLIMLVCAGIFVVVFGA
CCCCEEECCCCEEEEECCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
MFYALIKHRKSAGHPAAHFHENTTVEIIWTVIPFIILMGMAYPAAKVVIDMKDTSNPDLT
HHHHHHHHHHCCCCCHHHHCCCCCEEHHHHHHHHHHHHHCCCCCEEEEEEECCCCCCCEE
IKVTGYQWKWGYDYLNEDISFYSTLATPRAQITGAAPKGENYLLEVDEPVVVPVGKRVRM
EEEECEEEECCHHHHCCHHHHHHHHCCCCCEEECCCCCCCCEEEEECCCEEEECCCCEEE
LITANDVLHAWWVPALGAKQDAIPGFIRDIWFKADAVGTYRGQCVELCGKDHGFMPIVVE
EEEECHHHHHHHCCCCCCCCCCCHHHHHHHHHHHCCCCCHHHHHHHHHCCCCCCHHHHHH
VVSQADYEAWVAGKKSAAKRAEADNTREFSVAELVERGQKVYESNCAACHQADGKGLAGS
HHHHCCHHHHHCCCHHHHHHCCCCCCCCHHHHHHHHHHHHHHHCCCHHHHCCCCCCCCCC
FPAISGSKVATGPIADHIALVLNGRPGTAMAAFAKQLSDADIAAVVTYQRNAWDNKTGDR
CCCCCCCCEECCCCCCEEEEEEECCCCHHHHHHHHHHCCCCEEEEEEEECCCCCCCCCCC
VQPADIASARGGAKVAAASAAQ
CCCHHHHCCCCCCEECCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 2820725; 7651515; 9380672 [H]