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The map label for this gene is pimB [H]

Identifier: 74316311

GI number: 74316311

Start: 312837

End: 314057

Strand: Direct

Name: pimB [H]

Synonym: Tbd_0293

Alternate gene names: 74316311

Gene position: 312837-314057 (Clockwise)

Preceding gene: 74316310

Following gene: 74316312

Centisome position: 10.75

GC content: 69.21

Gene sequence:

>1221_bases
ATGAAGATCCTGCACGTATTCGACCACACGCTGCCGCTGCATTCCGGCTACACCTTCCGCAGCGCGGCGATCCTGCGCAA
CCAGCAGAAGCTGGGCTGGCAGACCTTCCACCTCTCTGGCCCCAAGCAGGTCGATTGCAGCGTCGCCGAAGAGGACGCCG
ACGGCCTGCATTTCTACCGCACGCCCAGACCTGAAGGCGTGCTCGCGCGGCTGCCCGGCGGCGATCCCTTCGCCGTCATG
GCCGCGATCGAGAAACGCCTGCTGCCGCTCGCGCGCGAGCTGCGTCCCGACGTCCTGCACGCCCACTCGCCCGTGCTCGA
CGCGATGCCGGCGCTTCGCGTCGGCCGCAAACTCGGCATTCCGGTGGTGTACGAAATCCGCGCGTTCTGGGAAGACGCCG
CGGTCGACCACGGCAGCACGACCGAAGGCAGCCTGCGCTATCGCCTCACGCGCGCGCTCGAAACGCGCGCCGTGAAGCAG
GCCGACGCCGTCACGGTGATCTGCGAGGGGCTGCGCGCGGATCTGGTCGCGCGCGGCATCCCCGCCGGCAAGATCACGGT
CATTCCGAACGCGGTCGACGTCGACAAGTTTGCGGTCGGCGGCCAGGCCGACCCCGAACTCAAGATGAAGCTCGGCCTCG
GGGCCAGCCGCGTGCTCGGCTTCATCGGCTCGTTCTATGCCTACGAAGGCCTCGACCTGCTGATCGGCGCCTTGCCGGCG
ATCACCGCGCGTGCGCCCGACGTGAAGGTGCTGCTCGTCGGCGGCGGCCCGCAGGACGCCGCGCTCAAGGCGCAGGTGAT
GGCCCTCGGCCTCAAGGATCGCGTCGTCTTCGCCGGCCGCGTCCCGCACGCCGAGGTCAACCGCTACTACGATCTCGTCG
ACGTGCTCGTCTACGCCCGACATCCGATGCGGCTGACCGAACTCGTCACGCCGCTGAAGCCGCTCGAGGCCATGGCGCAG
GGCCGGCTCATGGTCGCGTCCGACGTCGGCGGCCACCGGGAACTGATCGACGACGGCAAGACCGGCGTGTTGTTCCGCGC
CGGTGACGCCGACGACCTCGCGCGCAAGGCGGTCGCGCTGCTCGACAACGCATCCGACTGGGAACGCATCAAGGCGAACG
GCCGGCGCTTCGTCGAGACCGAGCGCAACTGGGCGGCGAGCGTCGCCCGTTATCGCGGCGTCTACCAGCGTCTCGTGCAG
ACGGAGGCGGTGCTTGACTGA

Upstream 100 bases:

>100_bases
CCGGCCGCCGCGATTTTTCGGTGATCCTGTGGACCGTCCTGATGTTCGACGCCTTCCTCGGCCAGGTGCTGGGCCTCGAC
GACACGGCGCGCGAGGCGGC

Downstream 100 bases:

>100_bases
AGCGCGCGGCGGCGGCGCCGAGATCGTCGTGTTCAGTTCGCTGTTCCCGAGCGCGGCACGCCCGGGTGCCGGGCTTTTCA
TCCGCGAGCGCATGTTCCGC

Product: group 1 glycosyl transferase

Products: NA

Alternate protein names: Alpha-D-mannose-alpha-(1-6)-phosphatidylmyo-inositol-mannosyltransferase; Alpha-mannosyltransferase; Alpha-manT; Guanosine diphosphomannose-phosphatidyl-inositol alpha-mannosyltransferase; Phosphatidylinositol alpha-mannosyltransferase; PI alpha-mannosyltransferase [H]

Number of amino acids: Translated: 406; Mature: 406

Protein sequence:

>406_residues
MKILHVFDHTLPLHSGYTFRSAAILRNQQKLGWQTFHLSGPKQVDCSVAEEDADGLHFYRTPRPEGVLARLPGGDPFAVM
AAIEKRLLPLARELRPDVLHAHSPVLDAMPALRVGRKLGIPVVYEIRAFWEDAAVDHGSTTEGSLRYRLTRALETRAVKQ
ADAVTVICEGLRADLVARGIPAGKITVIPNAVDVDKFAVGGQADPELKMKLGLGASRVLGFIGSFYAYEGLDLLIGALPA
ITARAPDVKVLLVGGGPQDAALKAQVMALGLKDRVVFAGRVPHAEVNRYYDLVDVLVYARHPMRLTELVTPLKPLEAMAQ
GRLMVASDVGGHRELIDDGKTGVLFRAGDADDLARKAVALLDNASDWERIKANGRRFVETERNWAASVARYRGVYQRLVQ
TEAVLD

Sequences:

>Translated_406_residues
MKILHVFDHTLPLHSGYTFRSAAILRNQQKLGWQTFHLSGPKQVDCSVAEEDADGLHFYRTPRPEGVLARLPGGDPFAVM
AAIEKRLLPLARELRPDVLHAHSPVLDAMPALRVGRKLGIPVVYEIRAFWEDAAVDHGSTTEGSLRYRLTRALETRAVKQ
ADAVTVICEGLRADLVARGIPAGKITVIPNAVDVDKFAVGGQADPELKMKLGLGASRVLGFIGSFYAYEGLDLLIGALPA
ITARAPDVKVLLVGGGPQDAALKAQVMALGLKDRVVFAGRVPHAEVNRYYDLVDVLVYARHPMRLTELVTPLKPLEAMAQ
GRLMVASDVGGHRELIDDGKTGVLFRAGDADDLARKAVALLDNASDWERIKANGRRFVETERNWAASVARYRGVYQRLVQ
TEAVLD
>Mature_406_residues
MKILHVFDHTLPLHSGYTFRSAAILRNQQKLGWQTFHLSGPKQVDCSVAEEDADGLHFYRTPRPEGVLARLPGGDPFAVM
AAIEKRLLPLARELRPDVLHAHSPVLDAMPALRVGRKLGIPVVYEIRAFWEDAAVDHGSTTEGSLRYRLTRALETRAVKQ
ADAVTVICEGLRADLVARGIPAGKITVIPNAVDVDKFAVGGQADPELKMKLGLGASRVLGFIGSFYAYEGLDLLIGALPA
ITARAPDVKVLLVGGGPQDAALKAQVMALGLKDRVVFAGRVPHAEVNRYYDLVDVLVYARHPMRLTELVTPLKPLEAMAQ
GRLMVASDVGGHRELIDDGKTGVLFRAGDADDLARKAVALLDNASDWERIKANGRRFVETERNWAASVARYRGVYQRLVQ
TEAVLD

Specific function: Catalyzes the addition of a mannose residue from GDP-D- mannose to the position 6 of a phosphatidyl-myo-inositol bearing an alpha-1,2-linked mannose residue (PIM1) to generate phosphatidyl-myo-inositol bearing alpha-1,2- and alpha-1,6-linked mannose resid

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 1 family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17532709, Length=308, Percent_Identity=24.025974025974, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001296 [H]

Pfam domain/function: PF00534 Glycos_transf_1 [H]

EC number: =2.4.1.57 [H]

Molecular weight: Translated: 44337; Mature: 44337

Theoretical pI: Translated: 8.92; Mature: 8.92

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.0 %Met     (Translated Protein)
2.5 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
2.5 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKILHVFDHTLPLHSGYTFRSAAILRNQQKLGWQTFHLSGPKQVDCSVAEEDADGLHFYR
CEEEEEECCCCCCCCCCCHHHHHHHHCHHHCCEEEEECCCCCCCCCEECCCCCCCCEEEE
TPRPEGVLARLPGGDPFAVMAAIEKRLLPLARELRPDVLHAHSPVLDAMPALRVGRKLGI
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCCC
PVVYEIRAFWEDAAVDHGSTTEGSLRYRLTRALETRAVKQADAVTVICEGLRADLVARGI
CEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAGKITVIPNAVDVDKFAVGGQADPELKMKLGLGASRVLGFIGSFYAYEGLDLLIGALPA
CCCEEEEECCCCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHH
ITARAPDVKVLLVGGGPQDAALKAQVMALGLKDRVVFAGRVPHAEVNRYYDLVDVLVYAR
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCC
HPMRLTELVTPLKPLEAMAQGRLMVASDVGGHRELIDDGKTGVLFRAGDADDLARKAVAL
CCCHHHHHHCCHHHHHHHHCCCEEEEECCCCCHHHHCCCCCEEEEECCCHHHHHHHHHHH
LDNASDWERIKANGRRFVETERNWAASVARYRGVYQRLVQTEAVLD
HCCCCHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MKILHVFDHTLPLHSGYTFRSAAILRNQQKLGWQTFHLSGPKQVDCSVAEEDADGLHFYR
CEEEEEECCCCCCCCCCCHHHHHHHHCHHHCCEEEEECCCCCCCCCEECCCCCCCCEEEE
TPRPEGVLARLPGGDPFAVMAAIEKRLLPLARELRPDVLHAHSPVLDAMPALRVGRKLGI
CCCCCCEEEECCCCCHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHHHHCCC
PVVYEIRAFWEDAAVDHGSTTEGSLRYRLTRALETRAVKQADAVTVICEGLRADLVARGI
CEEEHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
PAGKITVIPNAVDVDKFAVGGQADPELKMKLGLGASRVLGFIGSFYAYEGLDLLIGALPA
CCCEEEEECCCCCCCCEECCCCCCCCEEEEECCCHHHHHHHHHHHHHHCCHHHHHHHHHH
ITARAPDVKVLLVGGGPQDAALKAQVMALGLKDRVVFAGRVPHAEVNRYYDLVDVLVYAR
HHCCCCCEEEEEECCCCCCHHHHHHHHHCCCCCCEEEECCCCCHHHHHHHHHHHHHHHCC
HPMRLTELVTPLKPLEAMAQGRLMVASDVGGHRELIDDGKTGVLFRAGDADDLARKAVAL
CCCHHHHHHCCHHHHHHHHCCCEEEEECCCCCHHHHCCCCCEEEEECCCHHHHHHHHHHH
LDNASDWERIKANGRRFVETERNWAASVARYRGVYQRLVQTEAVLD
HCCCCHHHHHHHCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA