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The map label for this gene is qseC [H]

Identifier: 74316153

GI number: 74316153

Start: 144248

End: 145615

Strand: Reverse

Name: qseC [H]

Synonym: Tbd_0135

Alternate gene names: 74316153

Gene position: 145615-144248 (Counterclockwise)

Preceding gene: 74316154

Following gene: 74316148

Centisome position: 5.0

GC content: 72.37

Gene sequence:

>1368_bases
GTGAGCGAGGCGCGCGCCTATTCGCTGCGGCGGCGGCTGGTCGGGCTGCTGACGGCTGCGATCGCGCTGGTCTGGCTGCT
GTCGGCGCTATTCGTCTACGCGCGCGCCCACCACGAAGCCGACGAACTGCTCGACAGCCAGCTGACGGAGGTGGCGGAGA
CGCTGCTCGCGATCGTCGCGGCCGGCGAAGTCGACCATTTCGTCGAGGAATTGCACGAACACGCAGAAGGCTATCCGGTC
CCGATCGCGTTCGAAATCTGGCATACCGACGACGGCGTCTCCCGTCGCCTGGTCGCTTCACCGGGCTACGCGGGCTTCGA
CACCCCCGCGCCGAGCGGCTTCAGCGAACGGACCCATCAGGACGCCCCGTGGCGGTTCTACACGGCGCAGGACGAAGAGG
CGGCGTACCGCGTCGTCGTCGGCCAGGCCCACGGTGTGCGCGAACGGCTCGCGCGCGAGATCGGGCTGTCGCTGCTGCTG
CCTGCCGCGCTCGCGCTGCCGCTCATGGCGCTCGTCGTCTGGTGGGTCGTCGGCCGTACCTTGCGGCCGGTCGACGCGGT
CGCGCGCGAGGTCGGGGCGCTCGACCCTCGGACACTGAGCCCACTCGACCCATCGGTCGCGCTGCCGGACGAGATCGCGC
CGCTGCGCGCAGCGCTCAATGCCTTGATCGAGCGCGTCACCCGCGCCTTCGAAAACGAGCGTCGGTTCACCGCCGATGCG
GCGCACGAACTGCGCACGCCGCTGGCGGCGCTCAAGGTCCAGGCGCAGGTCGCGCAGCGCGCGCAGGCGGACGAAGCGCG
CCGGCACGCGCTGGGGCAGGTCGTCGCCGGCGTCGACCGCATGACCCATCTGGTCGAGCAGTTGCTGACCTTGGCCCGCG
TCGACCCCGCCCGCCAGCGGACGCCGCCCGAGCCGCTCGATCCCGCGGCGACCGTGACGCAGGTGTGCGCCGAACTGCAG
CCGCGCGCCGCGCAGCGCAAGCAGTCGCTGCAGGTCGACGCGCCGTCCGGCTGCCAGGTCGCAGTCGACCCGGTCTGGCT
CGCGATCGCCTTGCGCAATCTCGTCGACAATGCCATCGCCTATGCCGGGGCCGGCGCGCACATCGAGGTCAGGCTGGCAG
GCCACGGCGCGGCCTGTACGCTGAGCGTGGCCGACGACGGGCCCGGCGTCGATCCCGGACTGCGCAGCCGCCTGAGCGCG
CGTTTCGTGCGCGGCGAGAGCGGCGGAGACGGCTGCGGCCTGGGCCTGTCGATCGCCGCGCGCGTCGCCGAGTTGTCGAA
CGCGCGGCTCGAACTCGGCGAAGGCCTCAGGCGCGCCGATGAAGGGTATGGCTTCGCGGCGACGCTCCGCTTCGCCGCCC
CCGGATAG

Upstream 100 bases:

>100_bases
GCAACGCGCTCGAGGTTCATGTCCATCACCTGCGACGCAAGCTCGGCAACGACGTGATCCGCACCGTCCGCGGCGTCGGC
TACATGGCGGCGCCCCCGAC

Downstream 100 bases:

>100_bases
GCCGCGTCAGCGACCGTAGCCCGGTCCGCCGCCGGGACCGGCACCGCGACCCGTGCCGCTGCCCGGCCCCATGCCCGCCG
GCGGCGCGTCGGGCAGGGTC

Product: periplasmic sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 455; Mature: 454

Protein sequence:

>455_residues
MSEARAYSLRRRLVGLLTAAIALVWLLSALFVYARAHHEADELLDSQLTEVAETLLAIVAAGEVDHFVEELHEHAEGYPV
PIAFEIWHTDDGVSRRLVASPGYAGFDTPAPSGFSERTHQDAPWRFYTAQDEEAAYRVVVGQAHGVRERLAREIGLSLLL
PAALALPLMALVVWWVVGRTLRPVDAVAREVGALDPRTLSPLDPSVALPDEIAPLRAALNALIERVTRAFENERRFTADA
AHELRTPLAALKVQAQVAQRAQADEARRHALGQVVAGVDRMTHLVEQLLTLARVDPARQRTPPEPLDPAATVTQVCAELQ
PRAAQRKQSLQVDAPSGCQVAVDPVWLAIALRNLVDNAIAYAGAGAHIEVRLAGHGAACTLSVADDGPGVDPGLRSRLSA
RFVRGESGGDGCGLGLSIAARVAELSNARLELGEGLRRADEGYGFAATLRFAAPG

Sequences:

>Translated_455_residues
MSEARAYSLRRRLVGLLTAAIALVWLLSALFVYARAHHEADELLDSQLTEVAETLLAIVAAGEVDHFVEELHEHAEGYPV
PIAFEIWHTDDGVSRRLVASPGYAGFDTPAPSGFSERTHQDAPWRFYTAQDEEAAYRVVVGQAHGVRERLAREIGLSLLL
PAALALPLMALVVWWVVGRTLRPVDAVAREVGALDPRTLSPLDPSVALPDEIAPLRAALNALIERVTRAFENERRFTADA
AHELRTPLAALKVQAQVAQRAQADEARRHALGQVVAGVDRMTHLVEQLLTLARVDPARQRTPPEPLDPAATVTQVCAELQ
PRAAQRKQSLQVDAPSGCQVAVDPVWLAIALRNLVDNAIAYAGAGAHIEVRLAGHGAACTLSVADDGPGVDPGLRSRLSA
RFVRGESGGDGCGLGLSIAARVAELSNARLELGEGLRRADEGYGFAATLRFAAPG
>Mature_454_residues
SEARAYSLRRRLVGLLTAAIALVWLLSALFVYARAHHEADELLDSQLTEVAETLLAIVAAGEVDHFVEELHEHAEGYPVP
IAFEIWHTDDGVSRRLVASPGYAGFDTPAPSGFSERTHQDAPWRFYTAQDEEAAYRVVVGQAHGVRERLAREIGLSLLLP
AALALPLMALVVWWVVGRTLRPVDAVAREVGALDPRTLSPLDPSVALPDEIAPLRAALNALIERVTRAFENERRFTADAA
HELRTPLAALKVQAQVAQRAQADEARRHALGQVVAGVDRMTHLVEQLLTLARVDPARQRTPPEPLDPAATVTQVCAELQP
RAAQRKQSLQVDAPSGCQVAVDPVWLAIALRNLVDNAIAYAGAGAHIEVRLAGHGAACTLSVADDGPGVDPGLRSRLSAR
FVRGESGGDGCGLGLSIAARVAELSNARLELGEGLRRADEGYGFAATLRFAAPG

Specific function: Member of a two-component regulatory system qseB/qseC. Activates the flagella regulon by activating transcription of flhDC. May activate qseB by phosphorylation [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 histidine kinase domain [H]

Homologues:

Organism=Escherichia coli, GI1789403, Length=465, Percent_Identity=34.8387096774194, Blast_Score=201, Evalue=5e-53,
Organism=Escherichia coli, GI1790551, Length=294, Percent_Identity=33.6734693877551, Blast_Score=131, Evalue=1e-31,
Organism=Escherichia coli, GI1786783, Length=273, Percent_Identity=28.9377289377289, Blast_Score=105, Evalue=4e-24,
Organism=Escherichia coli, GI1786600, Length=213, Percent_Identity=32.8638497652582, Blast_Score=96, Evalue=3e-21,
Organism=Escherichia coli, GI1788279, Length=293, Percent_Identity=26.6211604095563, Blast_Score=88, Evalue=1e-18,
Organism=Escherichia coli, GI1788393, Length=228, Percent_Identity=28.5087719298246, Blast_Score=87, Evalue=3e-18,
Organism=Escherichia coli, GI1790861, Length=298, Percent_Identity=30.2013422818792, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1787894, Length=217, Percent_Identity=31.3364055299539, Blast_Score=84, Evalue=2e-17,
Organism=Escherichia coli, GI1790346, Length=215, Percent_Identity=28.8372093023256, Blast_Score=80, Evalue=2e-16,
Organism=Escherichia coli, GI1786912, Length=241, Percent_Identity=30.7053941908714, Blast_Score=75, Evalue=9e-15,
Organism=Escherichia coli, GI1789808, Length=237, Percent_Identity=27.4261603375527, Blast_Score=72, Evalue=6e-14,
Organism=Escherichia coli, GI1787374, Length=275, Percent_Identity=22.9090909090909, Blast_Score=69, Evalue=5e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 48836; Mature: 48705

Theoretical pI: Translated: 5.76; Mature: 5.76

Prosite motif: PS50885 HAMP ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
0.7 %Met     (Translated Protein)
1.5 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
1.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEARAYSLRRRLVGLLTAAIALVWLLSALFVYARAHHEADELLDSQLTEVAETLLAIVA
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGEVDHFVEELHEHAEGYPVPIAFEIWHTDDGVSRRLVASPGYAGFDTPAPSGFSERTHQ
HCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
DAPWRFYTAQDEEAAYRVVVGQAHGVRERLAREIGLSLLLPAALALPLMALVVWWVVGRT
CCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LRPVDAVAREVGALDPRTLSPLDPSVALPDEIAPLRAALNALIERVTRAFENERRFTADA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AHELRTPLAALKVQAQVAQRAQADEARRHALGQVVAGVDRMTHLVEQLLTLARVDPARQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCC
TPPEPLDPAATVTQVCAELQPRAAQRKQSLQVDAPSGCQVAVDPVWLAIALRNLVDNAIA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
YAGAGAHIEVRLAGHGAACTLSVADDGPGVDPGLRSRLSARFVRGESGGDGCGLGLSIAA
HCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RVAELSNARLELGEGLRRADEGYGFAATLRFAAPG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC
>Mature Secondary Structure 
SEARAYSLRRRLVGLLTAAIALVWLLSALFVYARAHHEADELLDSQLTEVAETLLAIVA
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
AGEVDHFVEELHEHAEGYPVPIAFEIWHTDDGVSRRLVASPGYAGFDTPAPSGFSERTHQ
HCHHHHHHHHHHHHHCCCCCEEEEEEEECCCCCCCEEEECCCCCCCCCCCCCCCCCCCCC
DAPWRFYTAQDEEAAYRVVVGQAHGVRERLAREIGLSLLLPAALALPLMALVVWWVVGRT
CCCEEEEECCCCCCEEEEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCC
LRPVDAVAREVGALDPRTLSPLDPSVALPDEIAPLRAALNALIERVTRAFENERRFTADA
CCHHHHHHHHHCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHH
AHELRTPLAALKVQAQVAQRAQADEARRHALGQVVAGVDRMTHLVEQLLTLARVDPARQR
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHCC
TPPEPLDPAATVTQVCAELQPRAAQRKQSLQVDAPSGCQVAVDPVWLAIALRNLVDNAIA
CCCCCCCHHHHHHHHHHHHCHHHHHHHHCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHH
YAGAGAHIEVRLAGHGAACTLSVADDGPGVDPGLRSRLSARFVRGESGGDGCGLGLSIAA
HCCCCCEEEEEEECCCCEEEEEECCCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHH
RVAELSNARLELGEGLRRADEGYGFAATLRFAAPG
HHHHHHHHHHHHHHHHHHHHCCCCEEEEEEECCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796; 11929534 [H]