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The map label for this gene is pyrR [H]

Identifier: 74316121

GI number: 74316121

Start: 110467

End: 111027

Strand: Reverse

Name: pyrR [H]

Synonym: Tbd_0103

Alternate gene names: 74316121

Gene position: 111027-110467 (Counterclockwise)

Preceding gene: 74316122

Following gene: 74316120

Centisome position: 3.82

GC content: 68.63

Gene sequence:

>561_bases
ATGAGCGAAAAACCCGCAGGCAGGCGGACCTGCCTTTACAGCGCCGAGCAGTTGGAGGCGATCGTCAGGGACATGGCGCG
CCAGACCGTCGGCCTGCTCGCCGGACGCAGCCGCGTCGCGCTGGTCGGAATCCTGCGGCGCGGTGCACCGCTCGCCGGCC
GCCTGCACGCGCAGCTGCGCGACAACTGGGGCCGCGCCGACTGCGTCCGCTTCGACCTGCAGATCAAGCGCTACGCCGAC
GACCTCACCCTGCTCCACCCGGAGACGCAGCTGACCGAAAATCCCGCGCACGCCGCGATCGACCTGCGCGGACTGAGCGT
CGTTATCGTCGACGACGTGATGTACCACGGCAACTCGATGCTGCGCGCGGTCGAATACCTCGCCCGTCGCGAGCCGGCCG
AAATCCGCACCGCAGTGCTCGTCGACCGCGGCGTGACGACGCTGCCGGTGCGCAGCGACGTGGTCGGCGTACGCCTCGAC
GTCGCGCCTTCCGACATCATCGAGTGCAACGTTCCGCCCTACGAAGCCGATTTCCGGATCGATCTGCTGCAGCCCGCATA
G

Upstream 100 bases:

>100_bases
GGCAGGATCTCGGCCTCTAGATGAAACGCAGTGCGCACCCCCTCGCCGACGCTCGTTGCCGCCGGGACGCGCCCGGCGCG
CCCGACCGAGGTCTAATCGG

Downstream 100 bases:

>100_bases
TCCTGTGCCGCTCGCCCGCGCCGCGCGCTATGATCGAAATGGGAAGCCTCCCGTTCGCCATTGAGGAGAATAAGCATGAA
TAAATCGATGATGACAGGTG

Product: transcriptional regulator PyrR

Products: NA

Alternate protein names: Pyrimidine operon regulatory protein; Uracil phosphoribosyltransferase; UPRTase [H]

Number of amino acids: Translated: 186; Mature: 185

Protein sequence:

>186_residues
MSEKPAGRRTCLYSAEQLEAIVRDMARQTVGLLAGRSRVALVGILRRGAPLAGRLHAQLRDNWGRADCVRFDLQIKRYAD
DLTLLHPETQLTENPAHAAIDLRGLSVVIVDDVMYHGNSMLRAVEYLARREPAEIRTAVLVDRGVTTLPVRSDVVGVRLD
VAPSDIIECNVPPYEADFRIDLLQPA

Sequences:

>Translated_186_residues
MSEKPAGRRTCLYSAEQLEAIVRDMARQTVGLLAGRSRVALVGILRRGAPLAGRLHAQLRDNWGRADCVRFDLQIKRYAD
DLTLLHPETQLTENPAHAAIDLRGLSVVIVDDVMYHGNSMLRAVEYLARREPAEIRTAVLVDRGVTTLPVRSDVVGVRLD
VAPSDIIECNVPPYEADFRIDLLQPA
>Mature_185_residues
SEKPAGRRTCLYSAEQLEAIVRDMARQTVGLLAGRSRVALVGILRRGAPLAGRLHAQLRDNWGRADCVRFDLQIKRYADD
LTLLHPETQLTENPAHAAIDLRGLSVVIVDDVMYHGNSMLRAVEYLARREPAEIRTAVLVDRGVTTLPVRSDVVGVRLDV
APSDIIECNVPPYEADFRIDLLQPA

Specific function: Displays also a weak uracil phosphoribosyltransferase activity which is not physiologically significant [H]

COG id: COG2065

COG function: function code F; Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrR subfamily [H]

Homologues:

None

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000836
- InterPro:   IPR023050 [H]

Pfam domain/function: PF00156 Pribosyltran [H]

EC number: =2.4.2.9 [H]

Molecular weight: Translated: 20647; Mature: 20516

Theoretical pI: Translated: 6.93; Mature: 6.93

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.6 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
1.6 %Cys     (Mature Protein)
1.6 %Met     (Mature Protein)
3.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSEKPAGRRTCLYSAEQLEAIVRDMARQTVGLLAGRSRVALVGILRRGAPLAGRLHAQLR
CCCCCCCCHHEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
DNWGRADCVRFDLQIKRYADDLTLLHPETQLTENPAHAAIDLRGLSVVIVDDVMYHGNSM
CCCCCCEEEEEEEEEEECCCCEEEECCCHHCCCCCCCEEEEECCCEEEEEECHHHCCHHH
LRAVEYLARREPAEIRTAVLVDRGVTTLPVRSDVVGVRLDVAPSDIIECNVPPYEADFRI
HHHHHHHHHCCCHHHHEEEEECCCCEEECCCCCEEEEEEECCCCCEEECCCCCCCCCEEE
DLLQPA
EEECCC
>Mature Secondary Structure 
SEKPAGRRTCLYSAEQLEAIVRDMARQTVGLLAGRSRVALVGILRRGAPLAGRLHAQLR
CCCCCCCHHEEECHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCCHHHHHHHHH
DNWGRADCVRFDLQIKRYADDLTLLHPETQLTENPAHAAIDLRGLSVVIVDDVMYHGNSM
CCCCCCEEEEEEEEEEECCCCEEEECCCHHCCCCCCCEEEEECCCEEEEEECHHHCCHHH
LRAVEYLARREPAEIRTAVLVDRGVTTLPVRSDVVGVRLDVAPSDIIECNVPPYEADFRI
HHHHHHHHHCCCHHHHEEEEECCCCEEECCCCCEEEEEEECCCCCEEECCCCCCCCCEEE
DLLQPA
EEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA