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The map label for this gene is qseD [H]

Identifier: 73543129

GI number: 73543129

Start: 3791815

End: 3792867

Strand: Direct

Name: qseD [H]

Synonym: Reut_A3447

Alternate gene names: 73543129

Gene position: 3791815-3792867 (Clockwise)

Preceding gene: 73543124

Following gene: 73543130

Centisome position: 99.61

GC content: 69.71

Gene sequence:

>1053_bases
ATGCCTGCCGCAAAAAACATGGGCGCTGGCCCGTCCTTCGGGCCGCCGCGAATTGTGCCGATAATGCGGTCATCCGCGCC
TCAAGACCCGATCGCTGATCTCATGCACATCCGCTGGCTCGAAGACTTCATCTGCCTCGCCCAGGCCGGCAGCCTCGCGC
GCGCGGCCGAACTGCGCAACGTCACGCCGCCGGCGTTCGGGCGGCGCATGCAGGCGCTCGAAGTCTGGGCGGGCGCGCCG
CTGATCGACCGCAGCGCGTTTCCGGTACGCCTGACCGCCGAGGGCCGGCAGTTCCTTGAAGCCGCACAAAACGCGCTGCA
AACGCTAGAGGACGCACGCCTCGCACTGCGCACCGCCCATCGCGCCGATGCCAGCACCCTGACCATCGCCACCGGCAAGA
CGCTCGCGCGCTCGATGGTGCCGGCGTGGCTCGCAGGCCTGCGGCGGGTGCTGGGCCATGACAAGGCGGCAGCGGGCTTC
CGCACGCGCCTGTCGACGTTTCCGATGCACGATGCGCTCGCGATGTTCACCGAAGGCGATGCCGATTTCCTGCTGTGCTA
CAGCCCTCCGGATATCCCGGTGATGCTCGACGACGCGCGCTACCGTTTCCACATGGTGGGCGTGGAGCGGCTGGTATGCG
TGAGCGCCGCCGATGCGCGCGGCGCGCCGGAGTTCCGGTTGCAGGCCGCCAAGGGCGGCGCCCGCACGGCGCCCACGCCG
ATGATCGCCTACGCAGATAGCCTGACGCTCGGCCGCATGGTCAACCAGGAAATCGCGCGCCGCAAGCTTGCCAGCCGGCT
CGACGTGATCGCCGTCAGCGACTTTGCCGAGTCGGTGCACGAGATGGTGCGCCAGCGCATGGGGCTGGCATGGCTGCCGG
CGCGGCTGATCGCGGACGATCTCCATGCGGGGCGGCTGGTGCGCGCGACAGCGGGTCGCAGTGCGGAGGAGGTGGATCTG
GCACTGGAGATCCGCCTGTACCGCCAGCGTGCGCCGATGCGGCCACTGGCGGAGGCGTTCTGGGAAGCCGCGGTCAGCGA
GCCGCGCAGCTGA

Upstream 100 bases:

>100_bases
TTTCACAAGCGTGGAATTCGAATGCCTGCTCTAATTCGCCTGTTCTGTGGGCTATCGCGCAACATTGTCGGAGCGCGTGG
CTATCTGGCATGGGCCGAGG

Downstream 100 bases:

>100_bases
GGCATTGCCGAATTGGCAACCCTCCTTGCCAAAGGCGCAAGCCGCCGCCTGGCGCGCTCACTACCATCAGGCCAGCGTCG
TCCCCATTCCAAAAAATCCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: Quorum-sensing regulator protein D [H]

Number of amino acids: Translated: 350; Mature: 349

Protein sequence:

>350_residues
MPAAKNMGAGPSFGPPRIVPIMRSSAPQDPIADLMHIRWLEDFICLAQAGSLARAAELRNVTPPAFGRRMQALEVWAGAP
LIDRSAFPVRLTAEGRQFLEAAQNALQTLEDARLALRTAHRADASTLTIATGKTLARSMVPAWLAGLRRVLGHDKAAAGF
RTRLSTFPMHDALAMFTEGDADFLLCYSPPDIPVMLDDARYRFHMVGVERLVCVSAADARGAPEFRLQAAKGGARTAPTP
MIAYADSLTLGRMVNQEIARRKLASRLDVIAVSDFAESVHEMVRQRMGLAWLPARLIADDLHAGRLVRATAGRSAEEVDL
ALEIRLYRQRAPMRPLAEAFWEAAVSEPRS

Sequences:

>Translated_350_residues
MPAAKNMGAGPSFGPPRIVPIMRSSAPQDPIADLMHIRWLEDFICLAQAGSLARAAELRNVTPPAFGRRMQALEVWAGAP
LIDRSAFPVRLTAEGRQFLEAAQNALQTLEDARLALRTAHRADASTLTIATGKTLARSMVPAWLAGLRRVLGHDKAAAGF
RTRLSTFPMHDALAMFTEGDADFLLCYSPPDIPVMLDDARYRFHMVGVERLVCVSAADARGAPEFRLQAAKGGARTAPTP
MIAYADSLTLGRMVNQEIARRKLASRLDVIAVSDFAESVHEMVRQRMGLAWLPARLIADDLHAGRLVRATAGRSAEEVDL
ALEIRLYRQRAPMRPLAEAFWEAAVSEPRS
>Mature_349_residues
PAAKNMGAGPSFGPPRIVPIMRSSAPQDPIADLMHIRWLEDFICLAQAGSLARAAELRNVTPPAFGRRMQALEVWAGAPL
IDRSAFPVRLTAEGRQFLEAAQNALQTLEDARLALRTAHRADASTLTIATGKTLARSMVPAWLAGLRRVLGHDKAAAGFR
TRLSTFPMHDALAMFTEGDADFLLCYSPPDIPVMLDDARYRFHMVGVERLVCVSAADARGAPEFRLQAAKGGARTAPTPM
IAYADSLTLGRMVNQEIARRKLASRLDVIAVSDFAESVHEMVRQRMGLAWLPARLIADDLHAGRLVRATAGRSAEEVDLA
LEIRLYRQRAPMRPLAEAFWEAAVSEPRS

Specific function: Down-regulates expression of the flagellar regulon, decreasing motility [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1790783, Length=307, Percent_Identity=25.4071661237785, Blast_Score=107, Evalue=1e-24,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 38282; Mature: 38151

Theoretical pI: Translated: 9.89; Mature: 9.89

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.1 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
4.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAAKNMGAGPSFGPPRIVPIMRSSAPQDPIADLMHIRWLEDFICLAQAGSLARAAELRN
CCCCCCCCCCCCCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
VTPPAFGRRMQALEVWAGAPLIDRSAFPVRLTAEGRQFLEAAQNALQTLEDARLALRTAH
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RADASTLTIATGKTLARSMVPAWLAGLRRVLGHDKAAAGFRTRLSTFPMHDALAMFTEGD
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCC
ADFLLCYSPPDIPVMLDDARYRFHMVGVERLVCVSAADARGAPEFRLQAAKGGARTAPTP
CCEEEEECCCCCCEEECCCCEEEEEECHHHHHEEECCCCCCCCHHEEEECCCCCCCCCCC
MIAYADSLTLGRMVNQEIARRKLASRLDVIAVSDFAESVHEMVRQRMGLAWLPARLIADD
CEEECCCHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LHAGRLVRATAGRSAEEVDLALEIRLYRQRAPMRPLAEAFWEAAVSEPRS
HCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC
>Mature Secondary Structure 
PAAKNMGAGPSFGPPRIVPIMRSSAPQDPIADLMHIRWLEDFICLAQAGSLARAAELRN
CCCCCCCCCCCCCCCCEEEEHHCCCCCCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHCC
VTPPAFGRRMQALEVWAGAPLIDRSAFPVRLTAEGRQFLEAAQNALQTLEDARLALRTAH
CCCHHHHHHHHHHHHHCCCCCCCCCCCCEEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RADASTLTIATGKTLARSMVPAWLAGLRRVLGHDKAAAGFRTRLSTFPMHDALAMFTEGD
CCCCCEEEEECCHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHCCCHHHHHHHCCCC
ADFLLCYSPPDIPVMLDDARYRFHMVGVERLVCVSAADARGAPEFRLQAAKGGARTAPTP
CCEEEEECCCCCCEEECCCCEEEEEECHHHHHEEECCCCCCCCHHEEEECCCCCCCCCCC
MIAYADSLTLGRMVNQEIARRKLASRLDVIAVSDFAESVHEMVRQRMGLAWLPARLIADD
CEEECCCHHHHHHHHHHHHHHHHHHHHCEEHHHHHHHHHHHHHHHHCCCHHHHHHHHHHH
LHAGRLVRATAGRSAEEVDLALEIRLYRQRAPMRPLAEAFWEAAVSEPRS
HCCCCEEEECCCCCHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 7610040; 9278503; 7876157 [H]