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The map label for this gene is abgR [H]

Identifier: 73542970

GI number: 73542970

Start: 3594320

End: 3595270

Strand: Reverse

Name: abgR [H]

Synonym: Reut_A3287

Alternate gene names: 73542970

Gene position: 3595270-3594320 (Counterclockwise)

Preceding gene: 73542973

Following gene: 73542969

Centisome position: 94.45

GC content: 66.88

Gene sequence:

>951_bases
ATGAAGCTGCAACAACTGCGCATCCTGCTGGCCGTGGCCGAGCACGGCAGCATCCATGAGGCGTCGCGTTCGCTGCATAT
CTCGCAGCCGGCGCTGTCGAAGGCGATCGCGGAGCTCGAACGCGAACTCGGCGTCACGCTCATGTCGCGCTCGGTGCGCG
GCGTGAGCCTGACGGCCTACGGCGTGGCGCTGGTCAAGCGCGCCAGCGTGGTCGAACAGGAACTGCGGCACGCGCTGGAA
GATATCGAGTCGATCCGCGGCCATGCCGAGGCCGAACTCAATATCGGTTTCACGGCGGTCGCGTCCAGCGGGCCATTGCC
GGACGCCATGGCGGCGTTCCGCCAGCGCTTCCCGAACGTGGCGTTGCGTGGTTTCGAACTGCGCCCGCAGCAGATTCAGG
AGGGACTGCGCGAAGGGCGGCTCGATCTGGGGCTGATTTCCACCAATAGTGGACCCGGCTCGGCATCGTTCCAGTGGGAA
CCGCTGTTCTCGGTCGGCATGAAGCTGGCGGTGCGCACGGGCCACCCGCTGCGGCGCGCGCGGCGGCTGCGGCCGCTGCT
CGATGCCGACTGGCTCGTGCTCGACCCTGTCGACGACGCTGGCAGCCCGCTGGCCAGCCTGATGCGCCTGCACCGGCTCG
AAATGCCGAAACGCGTGGTGCAGACCGCGTCGAACCTGCTCGGACTGCAGCTCGCCACCAAGACCGACCTGGTCAGCATG
TGGTCGGATTTCGTCTTCTTCGGCACCGGCGGACCGCTGCAGCTGGTACGCGACGCGCTGACGCCGCTGCCGATCCAGGA
CGAATTGCCCGATTTCCGCGTGTTCCTGGTCTACCGCTCGATGGACCTGATGACCCACGTCTGCGCCGAATTCGTGCGCG
AGGTGCGCCATTGTGCCCGCCAGATGGAGGAGCCGCTGGCCACCATGCGCAAGTCCCGATCCGCTTCATAA

Upstream 100 bases:

>100_bases
GTTCGCGGGGAAGCGGCGTCCGCCGCGCATCGCAGGCCACGCCCGCAATCGGGGCGCGCTGCACTGCACGCGGGCTTGCT
GCACAAAAAGAAAGGAATCG

Downstream 100 bases:

>100_bases
GTGCCGGCACGATGTCACGGCGCCGCCGATGCCGCACAATGGCGGGCAGGAGACGCAACACCATATGGACAAACTCAAGC
AAATCGAAGCCTTTATCGCG

Product: LysR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 316; Mature: 316

Protein sequence:

>316_residues
MKLQQLRILLAVAEHGSIHEASRSLHISQPALSKAIAELERELGVTLMSRSVRGVSLTAYGVALVKRASVVEQELRHALE
DIESIRGHAEAELNIGFTAVASSGPLPDAMAAFRQRFPNVALRGFELRPQQIQEGLREGRLDLGLISTNSGPGSASFQWE
PLFSVGMKLAVRTGHPLRRARRLRPLLDADWLVLDPVDDAGSPLASLMRLHRLEMPKRVVQTASNLLGLQLATKTDLVSM
WSDFVFFGTGGPLQLVRDALTPLPIQDELPDFRVFLVYRSMDLMTHVCAEFVREVRHCARQMEEPLATMRKSRSAS

Sequences:

>Translated_316_residues
MKLQQLRILLAVAEHGSIHEASRSLHISQPALSKAIAELERELGVTLMSRSVRGVSLTAYGVALVKRASVVEQELRHALE
DIESIRGHAEAELNIGFTAVASSGPLPDAMAAFRQRFPNVALRGFELRPQQIQEGLREGRLDLGLISTNSGPGSASFQWE
PLFSVGMKLAVRTGHPLRRARRLRPLLDADWLVLDPVDDAGSPLASLMRLHRLEMPKRVVQTASNLLGLQLATKTDLVSM
WSDFVFFGTGGPLQLVRDALTPLPIQDELPDFRVFLVYRSMDLMTHVCAEFVREVRHCARQMEEPLATMRKSRSAS
>Mature_316_residues
MKLQQLRILLAVAEHGSIHEASRSLHISQPALSKAIAELERELGVTLMSRSVRGVSLTAYGVALVKRASVVEQELRHALE
DIESIRGHAEAELNIGFTAVASSGPLPDAMAAFRQRFPNVALRGFELRPQQIQEGLREGRLDLGLISTNSGPGSASFQWE
PLFSVGMKLAVRTGHPLRRARRLRPLLDADWLVLDPVDDAGSPLASLMRLHRLEMPKRVVQTASNLLGLQLATKTDLVSM
WSDFVFFGTGGPLQLVRDALTPLPIQDELPDFRVFLVYRSMDLMTHVCAEFVREVRHCARQMEEPLATMRKSRSAS

Specific function: Could be the regulator of the abg operon [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1787601, Length=296, Percent_Identity=31.7567567567568, Blast_Score=136, Evalue=2e-33,
Organism=Escherichia coli, GI1789506, Length=276, Percent_Identity=24.2753623188406, Blast_Score=87, Evalue=2e-18,
Organism=Escherichia coli, GI1790399, Length=177, Percent_Identity=33.8983050847458, Blast_Score=86, Evalue=2e-18,
Organism=Escherichia coli, GI157672245, Length=180, Percent_Identity=35.5555555555556, Blast_Score=86, Evalue=4e-18,
Organism=Escherichia coli, GI1788887, Length=230, Percent_Identity=29.5652173913043, Blast_Score=83, Evalue=3e-17,
Organism=Escherichia coli, GI87081904, Length=241, Percent_Identity=28.2157676348548, Blast_Score=81, Evalue=9e-17,
Organism=Escherichia coli, GI145693105, Length=180, Percent_Identity=27.2222222222222, Blast_Score=78, Evalue=6e-16,
Organism=Escherichia coli, GI1787879, Length=184, Percent_Identity=33.1521739130435, Blast_Score=77, Evalue=2e-15,
Organism=Escherichia coli, GI1787530, Length=183, Percent_Identity=27.8688524590164, Blast_Score=72, Evalue=4e-14,
Organism=Escherichia coli, GI1789204, Length=227, Percent_Identity=29.5154185022026, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788297, Length=173, Percent_Identity=30.635838150289, Blast_Score=71, Evalue=7e-14,
Organism=Escherichia coli, GI1788748, Length=163, Percent_Identity=29.4478527607362, Blast_Score=67, Evalue=2e-12,
Organism=Escherichia coli, GI1788296, Length=181, Percent_Identity=30.3867403314917, Blast_Score=65, Evalue=4e-12,
Organism=Escherichia coli, GI1790262, Length=201, Percent_Identity=26.865671641791, Blast_Score=63, Evalue=3e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 35054; Mature: 35054

Theoretical pI: Translated: 9.27; Mature: 9.27

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.5 %Met     (Translated Protein)
4.1 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.5 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKLQQLRILLAVAEHGSIHEASRSLHISQPALSKAIAELERELGVTLMSRSVRGVSLTAY
CCHHHHHHHHHHHCCCCHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GVALVKRASVVEQELRHALEDIESIRGHAEAELNIGFTAVASSGPLPDAMAAFRQRFPNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCHHHHHHHHHCCCC
ALRGFELRPQQIQEGLREGRLDLGLISTNSGPGSASFQWEPLFSVGMKLAVRTGHPLRRA
EECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECHHHHHCHHHHCCCCCHHHHH
RRLRPLLDADWLVLDPVDDAGSPLASLMRLHRLEMPKRVVQTASNLLGLQLATKTDLVSM
HHHCHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSDFVFFGTGGPLQLVRDALTPLPIQDELPDFRVFLVYRSMDLMTHVCAEFVREVRHCAR
HHHHEEECCCCHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
QMEEPLATMRKSRSAS
HHHHHHHHHHHHCCCC
>Mature Secondary Structure
MKLQQLRILLAVAEHGSIHEASRSLHISQPALSKAIAELERELGVTLMSRSVRGVSLTAY
CCHHHHHHHHHHHCCCCHHHHHHCEECCCHHHHHHHHHHHHHHHHHHHHCCCCCCCHHHH
GVALVKRASVVEQELRHALEDIESIRGHAEAELNIGFTAVASSGPLPDAMAAFRQRFPNV
HHHHHHHHHHHHHHHHHHHHHHHHHCCCCCEEEECCEEEECCCCCCCHHHHHHHHHCCCC
ALRGFELRPQQIQEGLREGRLDLGLISTNSGPGSASFQWEPLFSVGMKLAVRTGHPLRRA
EECCCCCCHHHHHHHHHHCCCEEEEEECCCCCCCCCEEECHHHHHCHHHHCCCCCHHHHH
RRLRPLLDADWLVLDPVDDAGSPLASLMRLHRLEMPKRVVQTASNLLGLQLATKTDLVSM
HHHCHHCCCCEEEECCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
WSDFVFFGTGGPLQLVRDALTPLPIQDELPDFRVFLVYRSMDLMTHVCAEFVREVRHCAR
HHHHEEECCCCHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHHHHHHHHHHHHHHHHHHHH
QMEEPLATMRKSRSAS
HHHHHHHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9097039; 9278503; 9829935 [H]