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The map label for this gene is caiD [C]

Identifier: 73542967

GI number: 73542967

Start: 3592129

End: 3592962

Strand: Direct

Name: caiD [C]

Synonym: Reut_A3284

Alternate gene names: 73542967

Gene position: 3592129-3592962 (Clockwise)

Preceding gene: 73542966

Following gene: 73542971

Centisome position: 94.37

GC content: 66.31

Gene sequence:

>834_bases
ATGAGCGCCAGCAGCACCGACCGCATCATTGTGACCATCGAAGACGGCGTTGCCGACGTCCGTCTCAACCGCGCGGACAA
GATGAACGCGCTCGATCCCGCGATGTTCGACGCATTGATCGCCACTGGCGAGCAATTGAAGCAGACACCGGACGTGCGCG
CGGTGGTGCTGTCGGGCGAAGGCCGCGCGTTCTGCGCGGGGCTGGACATGGAAAGCATGGCCGGCATGCTGGGCGGCGGC
GCGAGCGGCGATCCGGGTATCCGTCCGGGCCGTCTGGCTGCGCGCGTGCACGGCATTTCGAACCGTCCGCAATACGCCTG
CATGGTTTGGCGCGAACTGCCGGTGCCGGTATTCGCTGCCGTGCACGGCGTGGCCTTCGGTGGCGGACTACAGGTCGCAC
TCGGCGCCGATGTGCGCTTCGTCACGGCAGACACGAAGCTCTCCGTCATGGAGATCAAATGGGGCCTTGTGCCGGACATG
GCTGGCATGGTGCTGACGCGCGGACTTGTGCGTCCGGACCTGCTGCGCGAGTTGATCTACACCGGGCGTATTGTCACGGG
CGCCGAGGCGTGCGAACTTGGTCTGGCCACGCGCGTCGTCGACGATCCACGGGCCGCTGCGCTCGAGGCCGCGCGCCAGG
TCGCACAGAAGAACCCGCATGCCATTCGTGCTGCGAAGCGGCTGATGGAGGTGGTCGAGGCCGGCGATGACGCGGCCATT
CTGATGGCGGAATCGGTCGAGCAGGACAAGCTGGTCGGATCGCCAAATCAGCGTGAAGCGGTGCGCGCGAATCTGGAGAA
GCGTGCGCCGAGGTTCGAACCCGCGCAGCGCTAA

Upstream 100 bases:

>100_bases
CCGACCGTGCGGGACGAACGCATCGCATAGACCGTGATGCTCGCGCTCCCCGGTGCGGGCATTCATCCCGAACACTGTAC
GAATCAATAAGGAGCCGCGC

Downstream 100 bases:

>100_bases
CTGAGTCGCTGGCGGCGCCACCAGATTGCGTAGATCGCCACGTTAAGGACAAGCACAAACGCACCCAGCCACAGCTGTAT
GGCTGGGGTTAGTCCAGCCG

Product: enoyl-CoA hydratase

Products: NA

Alternate protein names: 3-hydroxypropionyl-CoA dehydratase [H]

Number of amino acids: Translated: 277; Mature: 276

Protein sequence:

>277_residues
MSASSTDRIIVTIEDGVADVRLNRADKMNALDPAMFDALIATGEQLKQTPDVRAVVLSGEGRAFCAGLDMESMAGMLGGG
ASGDPGIRPGRLAARVHGISNRPQYACMVWRELPVPVFAAVHGVAFGGGLQVALGADVRFVTADTKLSVMEIKWGLVPDM
AGMVLTRGLVRPDLLRELIYTGRIVTGAEACELGLATRVVDDPRAAALEAARQVAQKNPHAIRAAKRLMEVVEAGDDAAI
LMAESVEQDKLVGSPNQREAVRANLEKRAPRFEPAQR

Sequences:

>Translated_277_residues
MSASSTDRIIVTIEDGVADVRLNRADKMNALDPAMFDALIATGEQLKQTPDVRAVVLSGEGRAFCAGLDMESMAGMLGGG
ASGDPGIRPGRLAARVHGISNRPQYACMVWRELPVPVFAAVHGVAFGGGLQVALGADVRFVTADTKLSVMEIKWGLVPDM
AGMVLTRGLVRPDLLRELIYTGRIVTGAEACELGLATRVVDDPRAAALEAARQVAQKNPHAIRAAKRLMEVVEAGDDAAI
LMAESVEQDKLVGSPNQREAVRANLEKRAPRFEPAQR
>Mature_276_residues
SASSTDRIIVTIEDGVADVRLNRADKMNALDPAMFDALIATGEQLKQTPDVRAVVLSGEGRAFCAGLDMESMAGMLGGGA
SGDPGIRPGRLAARVHGISNRPQYACMVWRELPVPVFAAVHGVAFGGGLQVALGADVRFVTADTKLSVMEIKWGLVPDMA
GMVLTRGLVRPDLLRELIYTGRIVTGAEACELGLATRVVDDPRAAALEAARQVAQKNPHAIRAAKRLMEVVEAGDDAAIL
MAESVEQDKLVGSPNQREAVRANLEKRAPRFEPAQR

Specific function: Plays a role in autotrophic carbon fixation via the 3- hydroxypropionate/4-hydroxybutyrate cycle. Catalyzes the reversible dehydration of 3-hydroxypropionyl-CoA to form acryloyl- CoA, and the reversible dehydration of (S)-3-hydroxybutyryl-CoA to form crot

COG id: COG1024

COG function: function code I; Enoyl-CoA hydratase/carnithine racemase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the enoyl-CoA hydratase/isomerase family [H]

Homologues:

Organism=Homo sapiens, GI70995211, Length=221, Percent_Identity=30.7692307692308, Blast_Score=97, Evalue=2e-20,
Organism=Homo sapiens, GI4502327, Length=265, Percent_Identity=28.3018867924528, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI194097323, Length=271, Percent_Identity=25.830258302583, Blast_Score=75, Evalue=6e-14,
Organism=Homo sapiens, GI31542718, Length=203, Percent_Identity=25.1231527093596, Blast_Score=66, Evalue=4e-11,
Organism=Escherichia coli, GI221142681, Length=229, Percent_Identity=29.2576419213974, Blast_Score=81, Evalue=6e-17,
Organism=Escherichia coli, GI1787659, Length=273, Percent_Identity=28.2051282051282, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1788682, Length=196, Percent_Identity=32.1428571428571, Blast_Score=73, Evalue=2e-14,
Organism=Escherichia coli, GI1790281, Length=191, Percent_Identity=28.2722513089005, Blast_Score=72, Evalue=3e-14,
Organism=Escherichia coli, GI87082183, Length=276, Percent_Identity=24.2753623188406, Blast_Score=72, Evalue=5e-14,
Organism=Escherichia coli, GI1787660, Length=269, Percent_Identity=30.8550185873606, Blast_Score=71, Evalue=7e-14,
Organism=Caenorhabditis elegans, GI17540714, Length=237, Percent_Identity=31.2236286919831, Blast_Score=107, Evalue=9e-24,
Organism=Caenorhabditis elegans, GI17534483, Length=217, Percent_Identity=29.4930875576037, Blast_Score=97, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17536985, Length=263, Percent_Identity=25.4752851711027, Blast_Score=96, Evalue=1e-20,
Organism=Caenorhabditis elegans, GI17560910, Length=208, Percent_Identity=30.7692307692308, Blast_Score=79, Evalue=3e-15,
Organism=Caenorhabditis elegans, GI25144157, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI25144160, Length=217, Percent_Identity=29.0322580645161, Blast_Score=72, Evalue=3e-13,
Organism=Drosophila melanogaster, GI24653139, Length=265, Percent_Identity=29.4339622641509, Blast_Score=103, Evalue=9e-23,
Organism=Drosophila melanogaster, GI19920382, Length=215, Percent_Identity=31.6279069767442, Blast_Score=99, Evalue=2e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014748
- InterPro:   IPR001753
- InterPro:   IPR018376 [H]

Pfam domain/function: PF00378 ECH [H]

EC number: =4.2.1.116 [H]

Molecular weight: Translated: 29489; Mature: 29358

Theoretical pI: Translated: 6.30; Mature: 6.30

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
4.3 %Met     (Translated Protein)
5.4 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
4.0 %Met     (Mature Protein)
5.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSASSTDRIIVTIEDGVADVRLNRADKMNALDPAMFDALIATGEQLKQTPDVRAVVLSGE
CCCCCCCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEEEEECC
GRAFCAGLDMESMAGMLGGGASGDPGIRPGRLAARVHGISNRPQYACMVWRELPVPVFAA
CCEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHEECCCCCCCCEEEEEHHHCCCHHHHH
VHGVAFGGGLQVALGADVRFVTADTKLSVMEIKWGLVPDMAGMVLTRGLVRPDLLRELIY
HHHHEECCCEEEEECCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHH
TGRIVTGAEACELGLATRVVDDPRAAALEAARQVAQKNPHAIRAAKRLMEVVEAGDDAAI
HCCEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEE
LMAESVEQDKLVGSPNQREAVRANLEKRAPRFEPAQR
EEECCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC
>Mature Secondary Structure 
SASSTDRIIVTIEDGVADVRLNRADKMNALDPAMFDALIATGEQLKQTPDVRAVVLSGE
CCCCCCEEEEEEECCCEEEEECCCCCCCCCCHHHHHHHHHCCHHHHCCCCEEEEEEECC
GRAFCAGLDMESMAGMLGGGASGDPGIRPGRLAARVHGISNRPQYACMVWRELPVPVFAA
CCEEEECCCHHHHHHHHCCCCCCCCCCCCCHHHHEECCCCCCCCEEEEEHHHCCCHHHHH
VHGVAFGGGLQVALGADVRFVTADTKLSVMEIKWGLVPDMAGMVLTRGLVRPDLLRELIY
HHHHEECCCEEEEECCCEEEEEECCEEEEEEEECCCCCHHHHHHHHHHCCCHHHHHHHHH
TGRIVTGAEACELGLATRVVDDPRAAALEAARQVAQKNPHAIRAAKRLMEVVEAGDDAAI
HCCEEECHHHHHHHHHHHHCCCCHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCEEE
LMAESVEQDKLVGSPNQREAVRANLEKRAPRFEPAQR
EEECCCCHHHCCCCCCHHHHHHHHHHHCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA