Click here to switch to the map view.

The map label for this gene is gmhA [H]

Identifier: 73542947

GI number: 73542947

Start: 3574910

End: 3575497

Strand: Reverse

Name: gmhA [H]

Synonym: Reut_A3264

Alternate gene names: 73542947

Gene position: 3575497-3574910 (Counterclockwise)

Preceding gene: 73542948

Following gene: 73542946

Centisome position: 93.93

GC content: 67.01

Gene sequence:

>588_bases
ATGAGCATCGAAAGCATTCAGCAGCAATTCCTGGACAGCGCGGAAGCCAAGCGGCAGGCCGCGGCCGTGATGGCGCCGTA
TATCGACGCCGCGGTGGAGCGCATGGTCGGCGCGCTGACCAGCGGCAACAAAATCCTGGTGTGCGGCAACGGCGGCTCCG
CCGCCGACGCCCAGCACTTCGCCGCCGAACTGGTCGGGCGCTTCGAACGCGAGCGGCCCGGGCTGGCGGCGATTGCGCTG
ACCACGGACAGCTCGATCCTGACCGCCATCGGCAATGACTATGACTTCAGCGTGGTGTTCTCCAAGCAGGTCGAGGCGCT
GGGCCAGCCCGGCGACATCCTGCTGGCGCTCTCCACGTCGGGCAACTCGGGCAACGTGATCGCCGCCATCGAGGCTGCGC
GCCAGCGCGACATGAGCGTGGTCGCGCTGACCGGCAAGGGCGGCGGCCAGATCGGCGCCATGCTCGACGAATTCGATATC
CACCTGTGCGTGCCGAACGAGCGGACGGCGCGCGTACAGGAAGTTCACCTGCTCACCCTGCATTGCCTGTGCGATGGCAT
CGACGAGGCATTGCTCGGCGAAGCCTGA

Upstream 100 bases:

>100_bases
CCGGCGAGGCAGGCTGAGTGGGGCTCGGCGGCCGCGCTGGTTCATAATGCGCGGTAACGCGGCCCGTGCCGCGACAGCAA
CAACAAGGCCCCCTCGAGCG

Downstream 100 bases:

>100_bases
TCCACTTACCCCAGCTACAGCAAGGACAGCATGAAGAATCTGCCTTTCCAGGCCTCCCGCCTGACCCGCATCGCAATGAC
AGCCGCCGTGCTAGCGGTTG

Product: phosphoheptose isomerase

Products: NA

Alternate protein names: Sedoheptulose 7-phosphate isomerase [H]

Number of amino acids: Translated: 195; Mature: 194

Protein sequence:

>195_residues
MSIESIQQQFLDSAEAKRQAAAVMAPYIDAAVERMVGALTSGNKILVCGNGGSAADAQHFAAELVGRFERERPGLAAIAL
TTDSSILTAIGNDYDFSVVFSKQVEALGQPGDILLALSTSGNSGNVIAAIEAARQRDMSVVALTGKGGGQIGAMLDEFDI
HLCVPNERTARVQEVHLLTLHCLCDGIDEALLGEA

Sequences:

>Translated_195_residues
MSIESIQQQFLDSAEAKRQAAAVMAPYIDAAVERMVGALTSGNKILVCGNGGSAADAQHFAAELVGRFERERPGLAAIAL
TTDSSILTAIGNDYDFSVVFSKQVEALGQPGDILLALSTSGNSGNVIAAIEAARQRDMSVVALTGKGGGQIGAMLDEFDI
HLCVPNERTARVQEVHLLTLHCLCDGIDEALLGEA
>Mature_194_residues
SIESIQQQFLDSAEAKRQAAAVMAPYIDAAVERMVGALTSGNKILVCGNGGSAADAQHFAAELVGRFERERPGLAAIALT
TDSSILTAIGNDYDFSVVFSKQVEALGQPGDILLALSTSGNSGNVIAAIEAARQRDMSVVALTGKGGGQIGAMLDEFDIH
LCVPNERTARVQEVHLLTLHCLCDGIDEALLGEA

Specific function: Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate [H]

COG id: COG0279

COG function: function code G; Phosphoheptose isomerase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 SIS domain [H]

Homologues:

Organism=Escherichia coli, GI1789539, Length=189, Percent_Identity=50.7936507936508, Blast_Score=196, Evalue=1e-51,
Organism=Escherichia coli, GI1786416, Length=156, Percent_Identity=48.0769230769231, Blast_Score=146, Evalue=8e-37,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR020620
- InterPro:   IPR001347 [H]

Pfam domain/function: PF01380 SIS [H]

EC number: =5.3.1.28 [H]

Molecular weight: Translated: 20385; Mature: 20254

Theoretical pI: Translated: 4.35; Mature: 4.35

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.1 %Cys     (Translated Protein)
2.6 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.1 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSIESIQQQFLDSAEAKRQAAAVMAPYIDAAVERMVGALTSGNKILVCGNGGSAADAQHF
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
AAELVGRFERERPGLAAIALTTDSSILTAIGNDYDFSVVFSKQVEALGQPGDILLALSTS
HHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCEEEEEEEHHHHHCCCCCCEEEEEECC
GNSGNVIAAIEAARQRDMSVVALTGKGGGQIGAMLDEFDIHLCVPNERTARVQEVHLLTL
CCCCCEEEEEEHHHHCCCEEEEEECCCCCCCCCEEECCEEEEECCCCCCCHHHHHHHHHH
HCLCDGIDEALLGEA
HHHHCCHHHHHCCCC
>Mature Secondary Structure 
SIESIQQQFLDSAEAKRQAAAVMAPYIDAAVERMVGALTSGNKILVCGNGGSAADAQHF
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEECCCCCCCHHHHH
AAELVGRFERERPGLAAIALTTDSSILTAIGNDYDFSVVFSKQVEALGQPGDILLALSTS
HHHHHHHHHHCCCCEEEEEEECCCCEEEECCCCCEEEEEEEHHHHHCCCCCCEEEEEECC
GNSGNVIAAIEAARQRDMSVVALTGKGGGQIGAMLDEFDIHLCVPNERTARVQEVHLLTL
CCCCCEEEEEEHHHHCCCEEEEEECCCCCCCCCEEECCEEEEECCCCCCCHHHHHHHHHH
HCLCDGIDEALLGEA
HHHHCCHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA