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The map label for this gene is trpG [H]

Identifier: 73542708

GI number: 73542708

Start: 3326657

End: 3327274

Strand: Direct

Name: trpG [H]

Synonym: Reut_A3024

Alternate gene names: 73542708

Gene position: 3326657-3327274 (Clockwise)

Preceding gene: 73542707

Following gene: 73542709

Centisome position: 87.39

GC content: 62.3

Gene sequence:

>618_bases
ATGGCCTGGACTCCGACATCTGAACCAGGGAACAAGGGAGAAAAGGCCATGCTGCTGATGATCGACAACTACGATTCGTT
CACCTACAACCTCGTCCAGTACTTCGGCGAACTCGGCGAGGACGTGCGCACCTACCGCAACGACGAGATCACGATCGAGG
AAATCGAGGCGCTCAAGCCCGACCATATCTGCGTATCGCCGGGCCCGTGCAGCCCGAAGGAAGCCGGCATCTCGGTGGCC
GCGCTGCAGCACTTTGCCGGCAAGGTGCCGCTGCTCGGCGTGTGCCTCGGCCACCAGGCCATCGGCGAAGCGTTCGGCGG
CAAGGTGATCCGCGCGAAGCAAGTCATGCACGGCAAGGTCAGCACCATCGAGACCACGCAGCAAGGCGTGTTCGCCGGCC
TGCCCAAACACTTCGACGTGACGCGCTATCATTCGCTGGCGATCGAGCGCGAAACCCTGCCGGACTGCCTGGAAGTGACC
GCCTGGACGCCTGACGGCGAGATCATGGGCGTACGCCACAAGACGCTGGCCATCGAAGGCGTGCAGTTCCATCCCGAGTC
GATTCTTTCCGAACAAGGCCATGCGCTGCTGGCCAACTTCCTGAAGACGACGCGATGA

Upstream 100 bases:

>100_bases
GCCGCGGCCGGCATCGTTGCGGACTCGGACCCCGAAGCCGAATGGAGGGAAACCGAAGCCAAGGCGCGCGCCGTGATCCG
CGCGGCCGAGCAGGTCCAGG

Downstream 100 bases:

>100_bases
GACTGCTCGACACTGCCACGCCGTCCGTTTCGTCCATTCCCATCGCGCCGCACGCCACCCAACCGACCGAGACCGCCATG
ACCATCACCGCCCAGGAAGC

Product: anthranilate synthase component II

Products: NA

Alternate protein names: Glutamine amido-transferase [H]

Number of amino acids: Translated: 205; Mature: 204

Protein sequence:

>205_residues
MAWTPTSEPGNKGEKAMLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITIEEIEALKPDHICVSPGPCSPKEAGISVA
ALQHFAGKVPLLGVCLGHQAIGEAFGGKVIRAKQVMHGKVSTIETTQQGVFAGLPKHFDVTRYHSLAIERETLPDCLEVT
AWTPDGEIMGVRHKTLAIEGVQFHPESILSEQGHALLANFLKTTR

Sequences:

>Translated_205_residues
MAWTPTSEPGNKGEKAMLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITIEEIEALKPDHICVSPGPCSPKEAGISVA
ALQHFAGKVPLLGVCLGHQAIGEAFGGKVIRAKQVMHGKVSTIETTQQGVFAGLPKHFDVTRYHSLAIERETLPDCLEVT
AWTPDGEIMGVRHKTLAIEGVQFHPESILSEQGHALLANFLKTTR
>Mature_204_residues
AWTPTSEPGNKGEKAMLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITIEEIEALKPDHICVSPGPCSPKEAGISVAA
LQHFAGKVPLLGVCLGHQAIGEAFGGKVIRAKQVMHGKVSTIETTQQGVFAGLPKHFDVTRYHSLAIERETLPDCLEVTA
WTPDGEIMGVRHKTLAIEGVQFHPESILSEQGHALLANFLKTTR

Specific function: Catalyzes The Biosynthesis Of 4-Amino-4-Deoxychorismate (Adc) From Chorismate And Glutamine. [C]

COG id: COG0512

COG function: function code EH; Anthranilate/para-aminobenzoate synthases component II

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 glutamine amidotransferase type-1 domain [H]

Homologues:

Organism=Escherichia coli, GI1789760, Length=185, Percent_Identity=63.2432432432432, Blast_Score=258, Evalue=3e-70,
Organism=Escherichia coli, GI1787517, Length=189, Percent_Identity=43.9153439153439, Blast_Score=147, Evalue=4e-37,
Organism=Escherichia coli, GI1786215, Length=141, Percent_Identity=28.3687943262411, Blast_Score=65, Evalue=3e-12,
Organism=Saccharomyces cerevisiae, GI6322638, Length=205, Percent_Identity=47.8048780487805, Blast_Score=205, Evalue=3e-54,
Organism=Saccharomyces cerevisiae, GI6324361, Length=227, Percent_Identity=33.0396475770925, Blast_Score=90, Evalue=3e-19,
Organism=Drosophila melanogaster, GI281365319, Length=139, Percent_Identity=30.9352517985612, Blast_Score=71, Evalue=4e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006220
- InterPro:   IPR001317
- InterPro:   IPR011702
- InterPro:   IPR017926
- InterPro:   IPR000991
- InterPro:   IPR006221 [H]

Pfam domain/function: PF00117 GATase [H]

EC number: =4.1.3.27 [H]

Molecular weight: Translated: 22516; Mature: 22385

Theoretical pI: Translated: 5.79; Mature: 5.79

Prosite motif: PS00442 GATASE_TYPE_I

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
3.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAWTPTSEPGNKGEKAMLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITIEEIEALKP
CCCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCC
DHICVSPGPCSPKEAGISVAALQHFAGKVPLLGVCLGHQAIGEAFGGKVIRAKQVMHGKV
CCEEECCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHCCC
STIETTQQGVFAGLPKHFDVTRYHSLAIERETLPDCLEVTAWTPDGEIMGVRHKTLAIEG
HHHHHHHHHHHHCCCCCCCHHHHHHHEECHHCCCHHHHEEEECCCCCEEEEEEEEEEEEC
VQFHPESILSEQGHALLANFLKTTR
CEECHHHHHHHCCHHHHHHHHHHCC
>Mature Secondary Structure 
AWTPTSEPGNKGEKAMLLMIDNYDSFTYNLVQYFGELGEDVRTYRNDEITIEEIEALKP
CCCCCCCCCCCCCEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHCCCCEEHHHHHHCCC
DHICVSPGPCSPKEAGISVAALQHFAGKVPLLGVCLGHQAIGEAFGGKVIRAKQVMHGKV
CCEEECCCCCCHHHHCCHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCEEEHHHHHHCCC
STIETTQQGVFAGLPKHFDVTRYHSLAIERETLPDCLEVTAWTPDGEIMGVRHKTLAIEG
HHHHHHHHHHHHCCCCCCCHHHHHHHEECHHCCCHHHHEEEECCCCCEEEEEEEEEEEEC
VQFHPESILSEQGHALLANFLKTTR
CEECHHHHHHHCCHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 2105306; 10984043 [H]