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The map label for this gene is mtgA

Identifier: 73542539

GI number: 73542539

Start: 3127571

End: 3128329

Strand: Reverse

Name: mtgA

Synonym: Reut_A2854

Alternate gene names: 73542539

Gene position: 3128329-3127571 (Counterclockwise)

Preceding gene: 73542540

Following gene: 73542536

Centisome position: 82.18

GC content: 65.61

Gene sequence:

>759_bases
GTGCCCGTGGCCACCCGACAGCGCTCCGCGCGCGCCGCCGGCACGGCATTCTCCCCGCTGCGCTGGATCGGTTTCCTGCT
CGGCTGCATCGTGGCCGGCGTGGTTGCGATGCAGGTCTATTTCTTCCTGCAGATCGCCGCATGGCAGTACGTGGCGCCGT
CTTCCACGTCGTTCATGCGCGCCGAGCGCTGGCGCCTGTGCGGCTTCAACGTCTGGAACTGCAGCATCGACCGCCGCTGG
GTGCCGTACGACCAGATCTCGCGCAACCTCAAGCGCGCAGTGATCGCGAGCGAAGACGCTGACTTCGTCAATCATCCCGG
CTACGAAATCGACGCCATGCTCGACGCGTGGGAGCGCAACAAGAAGCGCGGCCGCGTCGTGCGCGGCGGTTCGACCATCA
CCCAGCAGCTCGCCAAGAACCTGTTCCTGTCGTCCGAGCAGCATTACCTGCGCAAGGGCCAGGAACTGGCCATCACGTGG
ATGCTCGAGTTCTGGCTCGACAAGCAGCGCATCTTCGAGATCTACCTGAATTCGGTGGAGTGGGGCGAAGGCGTGTTCGG
TGCGGAGGCTGCGGCGCAGCACTACTTCCGTACGAACGCCGGGAAGCTCGGCGTGGGCCAGGCGGCGCGCCTGGCGGCGG
CGCTGCCTGCGCCGAAGTGCTTCGACAAGAAGGAGTACTGCGCGAATGTGCGCGTGAACTTCAGGGTGAAGGCGGGGATT
ATTGCGCGGCGGATGGGGGCGGCTACGTTGCCGGATTGA

Upstream 100 bases:

>100_bases
AGCGTTCTACATCTGGCGCGGCGTGCGTCCGCGCACCGCGCCCGTGCTGGCCGACCTGCGCGCCGCGCTGCAGGCCGAGC
GCAAGGGCTGATCGCCGCCA

Downstream 100 bases:

>100_bases
CGGCTGGCGTTCCTTCTCTCCTCTCGCGCTTGCGGGAGAGGAGCGGGGGAGGGGAGTCAGCCTGTCGTTGTTTCGGCCCT
CAGCTCAACCACCCCTTCCG

Product: monofunctional biosynthetic peptidoglycan transglycosylase

Products: NA

Alternate protein names: Monofunctional TGase

Number of amino acids: Translated: 252; Mature: 251

Protein sequence:

>252_residues
MPVATRQRSARAAGTAFSPLRWIGFLLGCIVAGVVAMQVYFFLQIAAWQYVAPSSTSFMRAERWRLCGFNVWNCSIDRRW
VPYDQISRNLKRAVIASEDADFVNHPGYEIDAMLDAWERNKKRGRVVRGGSTITQQLAKNLFLSSEQHYLRKGQELAITW
MLEFWLDKQRIFEIYLNSVEWGEGVFGAEAAAQHYFRTNAGKLGVGQAARLAAALPAPKCFDKKEYCANVRVNFRVKAGI
IARRMGAATLPD

Sequences:

>Translated_252_residues
MPVATRQRSARAAGTAFSPLRWIGFLLGCIVAGVVAMQVYFFLQIAAWQYVAPSSTSFMRAERWRLCGFNVWNCSIDRRW
VPYDQISRNLKRAVIASEDADFVNHPGYEIDAMLDAWERNKKRGRVVRGGSTITQQLAKNLFLSSEQHYLRKGQELAITW
MLEFWLDKQRIFEIYLNSVEWGEGVFGAEAAAQHYFRTNAGKLGVGQAARLAAALPAPKCFDKKEYCANVRVNFRVKAGI
IARRMGAATLPD
>Mature_251_residues
PVATRQRSARAAGTAFSPLRWIGFLLGCIVAGVVAMQVYFFLQIAAWQYVAPSSTSFMRAERWRLCGFNVWNCSIDRRWV
PYDQISRNLKRAVIASEDADFVNHPGYEIDAMLDAWERNKKRGRVVRGGSTITQQLAKNLFLSSEQHYLRKGQELAITWM
LEFWLDKQRIFEIYLNSVEWGEGVFGAEAAAQHYFRTNAGKLGVGQAARLAAALPAPKCFDKKEYCANVRVNFRVKAGII
ARRMGAATLPD

Specific function: Cell wall formation

COG id: COG0744

COG function: function code M; Membrane carboxypeptidase (penicillin-binding protein)

Gene ontology:

Cell location: Cell membrane; Single-pass membrane protein (Potential)

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the glycosyltransferase 51 family

Homologues:

Organism=Escherichia coli, GI1789601, Length=152, Percent_Identity=45.3947368421053, Blast_Score=122, Evalue=2e-29,
Organism=Escherichia coli, GI87082258, Length=148, Percent_Identity=36.4864864864865, Blast_Score=91, Evalue=6e-20,
Organism=Escherichia coli, GI1786343, Length=149, Percent_Identity=33.5570469798658, Blast_Score=80, Evalue=1e-16,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): MTGA_CUPPJ (Q46XB8)

Other databases:

- EMBL:   CP000090
- RefSeq:   YP_297059.1
- ProteinModelPortal:   Q46XB8
- SMR:   Q46XB8
- GeneID:   3611865
- GenomeReviews:   CP000090_GR
- KEGG:   reu:Reut_A2854
- NMPDR:   fig|264198.3.peg.3460
- HOGENOM:   HBG685698
- OMA:   PESTAFQ
- ProtClustDB:   PRK00056
- BioCyc:   REUT264198:REUT_A2854-MONOMER
- HAMAP:   MF_00766
- InterPro:   IPR001264
- InterPro:   IPR011812
- TIGRFAMs:   TIGR02070

Pfam domain/function: PF00912 Transgly

EC number: 2.4.2.- [C]

Molecular weight: Translated: 28520; Mature: 28389

Theoretical pI: Translated: 10.24; Mature: 10.24

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

HASH(0x406eedac)-;

Cys/Met content:

2.0 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
4.4 %Cys+Met (Translated Protein)
2.0 %Cys     (Mature Protein)
2.0 %Met     (Mature Protein)
4.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPVATRQRSARAAGTAFSPLRWIGFLLGCIVAGVVAMQVYFFLQIAAWQYVAPSSTSFMR
CCCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHH
AERWRLCGFNVWNCSIDRRWVPYDQISRNLKRAVIASEDADFVNHPGYEIDAMLDAWERN
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHCC
KKRGRVVRGGSTITQQLAKNLFLSSEQHYLRKGQELAITWMLEFWLDKQRIFEIYLNSVE
HHCCCEEECCHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCC
WGEGVFGAEAAAQHYFRTNAGKLGVGQAARLAAALPAPKCFDKKEYCANVRVNFRVKAGI
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCCEEEEEEHHHH
IARRMGAATLPD
HHHHHCCCCCCH
>Mature Secondary Structure 
PVATRQRSARAAGTAFSPLRWIGFLLGCIVAGVVAMQVYFFLQIAAWQYVAPSSTSFMR
CCCCCCHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHEECCCCCHHHH
AERWRLCGFNVWNCSIDRRWVPYDQISRNLKRAVIASEDADFVNHPGYEIDAMLDAWERN
HHHHHCCCCEEEECCCCCCCCCHHHHHHHHHHHHHCCCCCCHHCCCCCCHHHHHHHHHCC
KKRGRVVRGGSTITQQLAKNLFLSSEQHYLRKGQELAITWMLEFWLDKQRIFEIYLNSVE
HHCCCEEECCHHHHHHHHHHHHCCCCHHHHHCCCCEEHHHHHHHHHCHHHHHHHHHCCCC
WGEGVFGAEAAAQHYFRTNAGKLGVGQAARLAAALPAPKCFDKKEYCANVRVNFRVKAGI
CCCCCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHCCCCCCCCCHHHHHCCEEEEEEHHHH
IARRMGAATLPD
HHHHHCCCCCCH

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 7.0

TargetDB status: NA

Availability: NA

References: NA