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The map label for this gene is arcB [H]

Identifier: 73542428

GI number: 73542428

Start: 3010436

End: 3012271

Strand: Reverse

Name: arcB [H]

Synonym: Reut_A2743

Alternate gene names: 73542428

Gene position: 3012271-3010436 (Counterclockwise)

Preceding gene: 73542435

Following gene: 73542426

Centisome position: 79.13

GC content: 66.29

Gene sequence:

>1836_bases
ATGCCGGCGCCCGCGCTTCCTTCACACATTCACTTGAACGCGCTGCTCAACCGGCTGTTGCCAAGAATCCTGCCGCCTCC
CGGCGCCCAGCTCGATATCGAGACGCGGGCCAAGCTGATGGCCATCGTCCATAAGGCCTCGCCGTCCGCTGCGGTGGCGG
CGGTACTGCTGCCGGCGTTGACCATCCTGGCCTTCTGGAACTCGGCCGACCATGCCGCGCTGCTTGGCTGGGGCGCCGTG
ATGCTGCTGCTGCTCGCTGGCGGCCTGTGGTTCTACCTGGGTTACCAGCGCGACGGTGCTTCCATGAGCCGTTCCGCCCA
CACGCGCAAGTGGTGGGGCAATATGCGCGCCCTGGCGTTCCTGACCGGGGTGACATGGGGCAGTTCCGCGGTGCTCCACA
TGTACACGGGCTCGGCGGTGTTCTCGAGCGTGCTTTACCTGTTGAGCCTGGGCGTGCTGGCCGGTGGTGCGGTATCCCAG
GCGCCCGTGCCGTCGAACCTCGCCTATGCGGGGATTCCCATCCTGGTGCCGAATCTGCTGATGGCCGAGATTGCGTTCCC
CGGCCATGGCATCTACGTGCAGCTGCTGCTCGTCATCTACGCGATGATGCTCGGCCGCCATGCGCTCGGCCTGCAGGGCA
CGCTGGTCAGGGCGATCCAGCTCGAAGGCGACAGCCGCCGTCTGGCCAAGCAATTCCAGGAGGAAAAAGAGCGTGCGCTG
CACGCGAGCGAGGAAAAATCCCGTTTCCTGGCCGCGGCCAGCCACGACTTGCGCCAGCCCGTGCATGCGCTGGTGATGCT
GGTGGAAGCGCTGCGCGCGCGCAACCAGTCCACGGTGCTGCATCCGCTGGTGGAGCAGGTCGCGGCCGGTACGCAGACCA
TCGACCTGCTGTTCCGCTCGCTGCTCGATCTCTCCAAGCTGGAGGGCCGCAAGGTGCTGCCCACGCTCGAGCCATGCGAG
CTGAGCGCGCTGATCCGCGATGTGATGAGTCAGTTCGCCGCCGATGCGCGCGAAAGCGGTCTGACGCTGACGCCACGCGT
GCCCGACGAACTCTTTGCGATGGCGGAGCCGGTGCTGCTGCGCCGCGCGCTATTCAACCTCGTGCAGAACGCGCTGCGCT
ATACCAAGCGCGGCGGCGTGCTGGTCACGGCCCGGCAGCGCCGCAAGCACGTGCGGCTGGAGGTGTGGGACACGGGCGCT
GGCATCTTGCCCGACCATTTGCCGGACATCTTTTCGCCGTACTACCAGGTGCATAACCCACAGCGCGATCCGTCGCAGGG
TCTCGGGTTGGGGCTGGCCATCTTCAAGGAATGCGTGCGCCTGATGCGCGGCACCTATGGCGTGCGTTCGGTGCCCGGCA
AGGGGTCGGTATTCTGGTTCGCGCTGGGCACGGTGCCCGATGAGACCGTTGCCAGCGTGCGCGAAATGCGCGCCATGGCG
GCGGCCGAGGAATCGAAGCCGGACAAGCTTCAGGGCACGGTACTCGTCGTCGACGACGATACCCAGATCCGCAAGGCATG
GATTGCGCTGATGGAGGCCTGGGGTATCCGCGTTGAGTGTGCAGCGCATGGCGCGGAAGCGGACAAACTGTTTGCCCAGG
GATTCCGACCGGACATCATCTTCTGCGACCTGCGGCTGCCAGGCAGCGAAAACGGCCTCGACCTGCTGGAGCGTTGGCAG
AACACCCAACCGCAGGCGCGCAGCGCCTTGCTGACCGGAGACCTGAAATCTGCCGCGTTGGCGGCGGCGGAGGAGGCGGG
ATATTTTGTGCTGCCGAAGCCCGTCGATCCGGCTTCACTGCGCATGCTGCTGCGTCGCTGGCTGCGCCCCGCCTGA

Upstream 100 bases:

>100_bases
GTCAAGTCACTGAATTTGTGGCGCAATCGGCCCACCTCCGTGGCGCGATACCGCAAAAGGCGGCATGATATGCGCCACCC
AAGAAGGGCGCGAAGCATGT

Downstream 100 bases:

>100_bases
CGGCGTGTGTCCCACCGGCGTTCCGACTTACTGGCGCAGGCGGAAGCGCTCCATGCGGGACATGACCTGCATGCGCGTAC
GCACGCCGAGCCGCTGCAGG

Product: response regulator receiver:ATP-binding region, ATPase-like:histidine kinase A, N-terminal

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 611; Mature: 610

Protein sequence:

>611_residues
MPAPALPSHIHLNALLNRLLPRILPPPGAQLDIETRAKLMAIVHKASPSAAVAAVLLPALTILAFWNSADHAALLGWGAV
MLLLLAGGLWFYLGYQRDGASMSRSAHTRKWWGNMRALAFLTGVTWGSSAVLHMYTGSAVFSSVLYLLSLGVLAGGAVSQ
APVPSNLAYAGIPILVPNLLMAEIAFPGHGIYVQLLLVIYAMMLGRHALGLQGTLVRAIQLEGDSRRLAKQFQEEKERAL
HASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSTVLHPLVEQVAAGTQTIDLLFRSLLDLSKLEGRKVLPTLEPCE
LSALIRDVMSQFAADARESGLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGGVLVTARQRRKHVRLEVWDTGA
GILPDHLPDIFSPYYQVHNPQRDPSQGLGLGLAIFKECVRLMRGTYGVRSVPGKGSVFWFALGTVPDETVASVREMRAMA
AAEESKPDKLQGTVLVVDDDTQIRKAWIALMEAWGIRVECAAHGAEADKLFAQGFRPDIIFCDLRLPGSENGLDLLERWQ
NTQPQARSALLTGDLKSAALAAAEEAGYFVLPKPVDPASLRMLLRRWLRPA

Sequences:

>Translated_611_residues
MPAPALPSHIHLNALLNRLLPRILPPPGAQLDIETRAKLMAIVHKASPSAAVAAVLLPALTILAFWNSADHAALLGWGAV
MLLLLAGGLWFYLGYQRDGASMSRSAHTRKWWGNMRALAFLTGVTWGSSAVLHMYTGSAVFSSVLYLLSLGVLAGGAVSQ
APVPSNLAYAGIPILVPNLLMAEIAFPGHGIYVQLLLVIYAMMLGRHALGLQGTLVRAIQLEGDSRRLAKQFQEEKERAL
HASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSTVLHPLVEQVAAGTQTIDLLFRSLLDLSKLEGRKVLPTLEPCE
LSALIRDVMSQFAADARESGLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGGVLVTARQRRKHVRLEVWDTGA
GILPDHLPDIFSPYYQVHNPQRDPSQGLGLGLAIFKECVRLMRGTYGVRSVPGKGSVFWFALGTVPDETVASVREMRAMA
AAEESKPDKLQGTVLVVDDDTQIRKAWIALMEAWGIRVECAAHGAEADKLFAQGFRPDIIFCDLRLPGSENGLDLLERWQ
NTQPQARSALLTGDLKSAALAAAEEAGYFVLPKPVDPASLRMLLRRWLRPA
>Mature_610_residues
PAPALPSHIHLNALLNRLLPRILPPPGAQLDIETRAKLMAIVHKASPSAAVAAVLLPALTILAFWNSADHAALLGWGAVM
LLLLAGGLWFYLGYQRDGASMSRSAHTRKWWGNMRALAFLTGVTWGSSAVLHMYTGSAVFSSVLYLLSLGVLAGGAVSQA
PVPSNLAYAGIPILVPNLLMAEIAFPGHGIYVQLLLVIYAMMLGRHALGLQGTLVRAIQLEGDSRRLAKQFQEEKERALH
ASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSTVLHPLVEQVAAGTQTIDLLFRSLLDLSKLEGRKVLPTLEPCEL
SALIRDVMSQFAADARESGLTLTPRVPDELFAMAEPVLLRRALFNLVQNALRYTKRGGVLVTARQRRKHVRLEVWDTGAG
ILPDHLPDIFSPYYQVHNPQRDPSQGLGLGLAIFKECVRLMRGTYGVRSVPGKGSVFWFALGTVPDETVASVREMRAMAA
AEESKPDKLQGTVLVVDDDTQIRKAWIALMEAWGIRVECAAHGAEADKLFAQGFRPDIIFCDLRLPGSENGLDLLERWQN
TQPQARSALLTGDLKSAALAAAEEAGYFVLPKPVDPASLRMLLRRWLRPA

Specific function: Member of the two-component regulatory system ArcB/ArcA. Sensor-regulator protein for anaerobic repression of the arc modulon. Activates ArcA via a four-step phosphorelay. ArcB can also dephosphorylate ArcA by a reverse phosphorelay involving His- 717 and

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 response regulatory domain [H]

Homologues:

Organism=Escherichia coli, GI48994928, Length=330, Percent_Identity=30, Blast_Score=127, Evalue=2e-30,
Organism=Escherichia coli, GI1788713, Length=375, Percent_Identity=25.8666666666667, Blast_Score=114, Evalue=1e-26,
Organism=Escherichia coli, GI145693157, Length=240, Percent_Identity=30.4166666666667, Blast_Score=110, Evalue=2e-25,
Organism=Escherichia coli, GI1789149, Length=237, Percent_Identity=27.4261603375527, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1786783, Length=251, Percent_Identity=30.6772908366534, Blast_Score=97, Evalue=2e-21,
Organism=Escherichia coli, GI87081816, Length=313, Percent_Identity=24.9201277955272, Blast_Score=94, Evalue=2e-20,
Organism=Escherichia coli, GI1790861, Length=232, Percent_Identity=30.6034482758621, Blast_Score=92, Evalue=1e-19,
Organism=Escherichia coli, GI1786600, Length=233, Percent_Identity=30.0429184549356, Blast_Score=90, Evalue=4e-19,
Organism=Escherichia coli, GI1790346, Length=220, Percent_Identity=28.6363636363636, Blast_Score=78, Evalue=1e-15,
Organism=Escherichia coli, GI1790436, Length=240, Percent_Identity=29.1666666666667, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI1788393, Length=259, Percent_Identity=27.7992277992278, Blast_Score=78, Evalue=2e-15,
Organism=Escherichia coli, GI87082128, Length=291, Percent_Identity=24.7422680412371, Blast_Score=71, Evalue=2e-13,
Organism=Escherichia coli, GI1786912, Length=260, Percent_Identity=28.4615384615385, Blast_Score=69, Evalue=1e-12,
Organism=Escherichia coli, GI1788549, Length=289, Percent_Identity=22.4913494809689, Blast_Score=63, Evalue=6e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR011006
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR008207
- InterPro:   IPR014409
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082
- InterPro:   IPR001789 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF01627 Hpt; PF00989 PAS; PF00072 Response_reg [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 66801; Mature: 66670

Theoretical pI: Translated: 9.65; Mature: 9.65

Prosite motif: PS50110 RESPONSE_REGULATORY ; PS50109 HIS_KIN ; PS00589 PTS_HPR_SER

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.3 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPAPALPSHIHLNALLNRLLPRILPPPGAQLDIETRAKLMAIVHKASPSAAVAAVLLPAL
CCCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TILAFWNSADHAALLGWGAVMLLLLAGGLWFYLGYQRDGASMSRSAHTRKWWGNMRALAF
HHHHHHCCCCCHHHHHHHHHHHHHHHCHHHEEEEECCCCCHHHHHHHHHHHHHCHHHHHH
LTGVTWGSSAVLHMYTGSAVFSSVLYLLSLGVLAGGAVSQAPVPSNLAYAGIPILVPNLL
HHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
MAEIAFPGHGIYVQLLLVIYAMMLGRHALGLQGTLVRAIQLEGDSRRLAKQFQEEKERAL
HHHHCCCCCHHHHHHHHHHHHHHHCCHHCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHH
HASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSTVLHPLVEQVAAGTQTIDLLFRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHH
LLDLSKLEGRKVLPTLEPCELSALIRDVMSQFAADARESGLTLTPRVPDELFAMAEPVLL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHH
RRALFNLVQNALRYTKRGGVLVTARQRRKHVRLEVWDTGAGILPDHLPDIFSPYYQVHNP
HHHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCC
QRDPSQGLGLGLAIFKECVRLMRGTYGVRSVPGKGSVFWFALGTVPDETVASVREMRAMA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
AAEESKPDKLQGTVLVVDDDTQIRKAWIALMEAWGIRVECAAHGAEADKLFAQGFRPDII
HHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCCCEE
FCDLRLPGSENGLDLLERWQNTQPQARSALLTGDLKSAALAAAEEAGYFVLPKPVDPASL
EEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCHHHH
RMLLRRWLRPA
HHHHHHHCCCC
>Mature Secondary Structure 
PAPALPSHIHLNALLNRLLPRILPPPGAQLDIETRAKLMAIVHKASPSAAVAAVLLPAL
CCCCCCCHHHHHHHHHHHHHHHCCCCCCEEEHHHHHHHHHHHHHCCCHHHHHHHHHHHH
TILAFWNSADHAALLGWGAVMLLLLAGGLWFYLGYQRDGASMSRSAHTRKWWGNMRALAF
HHHHHHCCCCCHHHHHHHHHHHHHHHCHHHEEEEECCCCCHHHHHHHHHHHHHCHHHHHH
LTGVTWGSSAVLHMYTGSAVFSSVLYLLSLGVLAGGAVSQAPVPSNLAYAGIPILVPNLL
HHHCCCCCCCEEEEECCHHHHHHHHHHHHHHHHCCCCCCCCCCCCCCCCCCCHHHHHHHH
MAEIAFPGHGIYVQLLLVIYAMMLGRHALGLQGTLVRAIQLEGDSRRLAKQFQEEKERAL
HHHHCCCCCHHHHHHHHHHHHHHHCCHHCCCCHHEEEEEEECCCHHHHHHHHHHHHHHHH
HASEEKSRFLAAASHDLRQPVHALVMLVEALRARNQSTVLHPLVEQVAAGTQTIDLLFRS
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHHHHCCHHHHHHHHHH
LLDLSKLEGRKVLPTLEPCELSALIRDVMSQFAADARESGLTLTPRVPDELFAMAEPVLL
HHHHHHCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHCCCEECCCCCHHHHHHHHHHHH
RRALFNLVQNALRYTKRGGVLVTARQRRKHVRLEVWDTGAGILPDHLPDIFSPYYQVHNP
HHHHHHHHHHHHHHHHCCCEEEEEHHHHCCEEEEEEECCCCCCCCCCHHHHHHHHHHCCC
QRDPSQGLGLGLAIFKECVRLMRGTYGVRSVPGKGSVFWFALGTVPDETVASVREMRAMA
CCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCEEEEEECCCCCHHHHHHHHHHHHH
AAEESKPDKLQGTVLVVDDDTQIRKAWIALMEAWGIRVECAAHGAEADKLFAQGFRPDII
HHHCCCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCEEEEECCCCHHHHHHHCCCCCCEE
FCDLRLPGSENGLDLLERWQNTQPQARSALLTGDLKSAALAAAEEAGYFVLPKPVDPASL
EEEEECCCCCCCHHHHHHHCCCCCHHHHHHHHCCHHHHHHHHHHHCCEEEECCCCCHHHH
RMLLRRWLRPA
HHHHHHHCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]