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The map label for this gene is mtaD [H]

Identifier: 73542397

GI number: 73542397

Start: 2977352

End: 2978758

Strand: Reverse

Name: mtaD [H]

Synonym: Reut_A2712

Alternate gene names: 73542397

Gene position: 2978758-2977352 (Counterclockwise)

Preceding gene: 73542398

Following gene: 73542396

Centisome position: 78.25

GC content: 69.23

Gene sequence:

>1407_bases
ATGAACGAAGCACGCATTCTTGCACCCCACGCGCTGCTGCCCACCGGCTGGGCGCGCGACGTGCTACTGGCATGGGATAC
AACGGGCCGCCTGACAACGGTGCAGGCGGGCGCATCGGCCAGTGCCGATGTGCCGCGCGCCGCCGGCCCCGTGCTGCCCG
GTATGCCGAATCTCCATTCGCACGCGTTCCAGCGCGGCTTTGCCGGCCTGACGGAATACCGCAGCGTGACGCAGGGCGGC
GATCCCGCCGGCGCAGACTCGTTCTGGAGCTGGCGCACGCTGATGTACCGCTTCGCGCTGCGCTTGTCGCCGGACACGCT
GGAGGCCATCGCCACGCAGCTCTACATCGAGATGCTGCGCGCGGGCTACACCAGCGTATGCGAGTTCCACTACGTGCACC
ACGACATCGACGGCAAGCCATATGCAGACGCGGCCGAGATGTCTTTGCGCCTGTTGCGCGCGGCCGAACGCGCTGGCATC
GGCATGACGCTGCTGCCGGTGCTGTACCAGACGGCCGGCTTCGGCGACAAGCCGGCGGTGGCGGAGCAGCGCCGCTTCCT
GCATGACACCGACGCCATGCTCAGGCTGCTCGAACGCCTGTCGCCCGCGTGCGCGCAGCACGGCGCGCGCCTGGGCCTCG
CCCCGCACTCGTTGCGCGCAGTGCCACAGCAAAGCCTCACGCACGCATTGGCCGGCCTGCATGCGATGGATCCTACTGCA
CCTGTGCACATCCACATCGCCGAGCAGCAGCGCGAGGTGGACGACTGCATCGCGCAGACCGGCATCCGGCCCGTCGAATG
GCTGCTCGACCATGCCGAGGTCGATGCGCGCTGGTGCCTTGTGCATGCCACGCATATGGACTGGGATGAACGCCGGCGCC
TCGCGCACAGCGGGGCGGTGGCTGGCATCTGTCCGACCACCGAGGCAAACCTGGGCGATGGCGTGTTCGAAGCGGCGCCG
TACCTCGCCCAGCACGGTGCATGGGGCATCGGCTCGGACAGCCATGCGAGCGTCAGCGTCGCCGAAGAGCTGCGCATGTT
CGAGTACGGCCAGCGGCTGGCCCTGCAGCAGCGCAATGTGCTGGCCTCGGAATCGCATATGCAGGTCGCGGATCGTCTCT
ACCTCGAGGCGGTGGCCGGCGGTGCGCGTGCAACGGGCCGCGCGGTAGCCGGGCTCGCGGCGGGCCAGCAGGCCGATTTC
GTCGTGCTCGATGGCTCGCATCCCGCGCTGGCGGGGCTTGACGGCGCCCAGGCGCTGGCCACGCACGTCTTTGCCAACCA
CGGCCATGAGACACTAGCGGAAGTCCGCACTGCCGGCCGTTGCCGCGTGCAGCATGGTGCGCATCCGCTGCAGGCGGAAG
CTGGCCAGCTGTTCGTGTCGGCGCGCGCGAGCCTGCTGGGCGACTGA

Upstream 100 bases:

>100_bases
GAACTGGCTTACTGGTTCGGCCGCAACCCGGCCGCGGTGGTCGTGCGGCAGGGACGCATCCATCCGGCGACGTCGCAACA
CGGCGGGAGGGCATGAGCGC

Downstream 100 bases:

>100_bases
AAACCGGCAGCCGCCGCATTGCGCGGCGCGCTGCCCTGCATTGCACAGACCATGTCCTTTTCTACCGACACCCCCGCTTT
TACCCTGCATCGCGGCACCC

Product: N-formimino-L-glutamate deiminase

Products: NA

Alternate protein names: MTA/SAH deaminase [H]

Number of amino acids: Translated: 468; Mature: 468

Protein sequence:

>468_residues
MNEARILAPHALLPTGWARDVLLAWDTTGRLTTVQAGASASADVPRAAGPVLPGMPNLHSHAFQRGFAGLTEYRSVTQGG
DPAGADSFWSWRTLMYRFALRLSPDTLEAIATQLYIEMLRAGYTSVCEFHYVHHDIDGKPYADAAEMSLRLLRAAERAGI
GMTLLPVLYQTAGFGDKPAVAEQRRFLHDTDAMLRLLERLSPACAQHGARLGLAPHSLRAVPQQSLTHALAGLHAMDPTA
PVHIHIAEQQREVDDCIAQTGIRPVEWLLDHAEVDARWCLVHATHMDWDERRRLAHSGAVAGICPTTEANLGDGVFEAAP
YLAQHGAWGIGSDSHASVSVAEELRMFEYGQRLALQQRNVLASESHMQVADRLYLEAVAGGARATGRAVAGLAAGQQADF
VVLDGSHPALAGLDGAQALATHVFANHGHETLAEVRTAGRCRVQHGAHPLQAEAGQLFVSARASLLGD

Sequences:

>Translated_468_residues
MNEARILAPHALLPTGWARDVLLAWDTTGRLTTVQAGASASADVPRAAGPVLPGMPNLHSHAFQRGFAGLTEYRSVTQGG
DPAGADSFWSWRTLMYRFALRLSPDTLEAIATQLYIEMLRAGYTSVCEFHYVHHDIDGKPYADAAEMSLRLLRAAERAGI
GMTLLPVLYQTAGFGDKPAVAEQRRFLHDTDAMLRLLERLSPACAQHGARLGLAPHSLRAVPQQSLTHALAGLHAMDPTA
PVHIHIAEQQREVDDCIAQTGIRPVEWLLDHAEVDARWCLVHATHMDWDERRRLAHSGAVAGICPTTEANLGDGVFEAAP
YLAQHGAWGIGSDSHASVSVAEELRMFEYGQRLALQQRNVLASESHMQVADRLYLEAVAGGARATGRAVAGLAAGQQADF
VVLDGSHPALAGLDGAQALATHVFANHGHETLAEVRTAGRCRVQHGAHPLQAEAGQLFVSARASLLGD
>Mature_468_residues
MNEARILAPHALLPTGWARDVLLAWDTTGRLTTVQAGASASADVPRAAGPVLPGMPNLHSHAFQRGFAGLTEYRSVTQGG
DPAGADSFWSWRTLMYRFALRLSPDTLEAIATQLYIEMLRAGYTSVCEFHYVHHDIDGKPYADAAEMSLRLLRAAERAGI
GMTLLPVLYQTAGFGDKPAVAEQRRFLHDTDAMLRLLERLSPACAQHGARLGLAPHSLRAVPQQSLTHALAGLHAMDPTA
PVHIHIAEQQREVDDCIAQTGIRPVEWLLDHAEVDARWCLVHATHMDWDERRRLAHSGAVAGICPTTEANLGDGVFEAAP
YLAQHGAWGIGSDSHASVSVAEELRMFEYGQRLALQQRNVLASESHMQVADRLYLEAVAGGARATGRAVAGLAAGQQADF
VVLDGSHPALAGLDGAQALATHVFANHGHETLAEVRTAGRCRVQHGAHPLQAEAGQLFVSARASLLGD

Specific function: Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L- homocysteine, respectively. Is also able to deaminate adenosine [H]

COG id: COG0402

COG function: function code FR; Cytosine deaminase and related metal-dependent hydrolases

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the MTA/SAH deaminase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI17540282, Length=426, Percent_Identity=28.4037558685446, Blast_Score=167, Evalue=8e-42,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR006680
- InterPro:   IPR011059 [H]

Pfam domain/function: PF01979 Amidohydro_1 [H]

EC number: =3.5.4.28 [H]

Molecular weight: Translated: 50360; Mature: 50360

Theoretical pI: Translated: 6.51; Mature: 6.51

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.6 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.4 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNEARILAPHALLPTGWARDVLLAWDTTGRLTTVQAGASASADVPRAAGPVLPGMPNLHS
CCCCEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
HAFQRGFAGLTEYRSVTQGGDPAGADSFWSWRTLMYRFALRLSPDTLEAIATQLYIEMLR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AGYTSVCEFHYVHHDIDGKPYADAAEMSLRLLRAAERAGIGMTLLPVLYQTAGFGDKPAV
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCH
AEQRRFLHDTDAMLRLLERLSPACAQHGARLGLAPHSLRAVPQQSLTHALAGLHAMDPTA
HHHHHHHCCHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCC
PVHIHIAEQQREVDDCIAQTGIRPVEWLLDHAEVDARWCLVHATHMDWDERRRLAHSGAV
CEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCC
AGICPTTEANLGDGVFEAAPYLAQHGAWGIGSDSHASVSVAEELRMFEYGQRLALQQRNV
EEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LASESHMQVADRLYLEAVAGGARATGRAVAGLAAGQQADFVVLDGSHPALAGLDGAQALA
HHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHH
THVFANHGHETLAEVRTAGRCRVQHGAHPLQAEAGQLFVSARASLLGD
HHHHHCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MNEARILAPHALLPTGWARDVLLAWDTTGRLTTVQAGASASADVPRAAGPVLPGMPNLHS
CCCCEEECCCCCCCCCCCCCEEEEECCCCCEEEEECCCCCCCCCCCCCCCCCCCCCCHHH
HAFQRGFAGLTEYRSVTQGGDPAGADSFWSWRTLMYRFALRLSPDTLEAIATQLYIEMLR
HHHHHHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHH
AGYTSVCEFHYVHHDIDGKPYADAAEMSLRLLRAAERAGIGMTLLPVLYQTAGFGDKPAV
CCHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHHHHHHCCCCHHHHHHHHHHCCCCCCCCH
AEQRRFLHDTDAMLRLLERLSPACAQHGARLGLAPHSLRAVPQQSLTHALAGLHAMDPTA
HHHHHHHCCHHHHHHHHHHHCHHHHHCCCCCCCCHHHHHHCCHHHHHHHHHHHHCCCCCC
PVHIHIAEQQREVDDCIAQTGIRPVEWLLDHAEVDARWCLVHATHMDWDERRRLAHSGAV
CEEEEEHHHHHHHHHHHHHCCCCHHHHHHHHHCCCCEEEEEEECCCCHHHHHHHHHCCCC
AGICPTTEANLGDGVFEAAPYLAQHGAWGIGSDSHASVSVAEELRMFEYGQRLALQQRNV
EEECCCCCCCCCCCHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHH
LASESHMQVADRLYLEAVAGGARATGRAVAGLAAGQQADFVVLDGSHPALAGLDGAQALA
HHCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHCCCCCCEEEEECCCCCCCCCCHHHHHH
THVFANHGHETLAEVRTAGRCRVQHGAHPLQAEAGQLFVSARASLLGD
HHHHHCCCHHHHHHHHHCCCEEECCCCCCCCHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA