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The map label for this gene is aroA [H]

Identifier: 73542257

GI number: 73542257

Start: 2816557

End: 2817861

Strand: Reverse

Name: aroA [H]

Synonym: Reut_A2572

Alternate gene names: 73542257

Gene position: 2817861-2816557 (Counterclockwise)

Preceding gene: 73542258

Following gene: 73542255

Centisome position: 74.03

GC content: 66.74

Gene sequence:

>1305_bases
ATGGAACACCTGACGCTTGGCCCTCTTACCCGCGCCGCGGGCACTGTCCGTTTGCCGGGCTCGAAAAGCATTTCGAACCG
CGTGCTGCTACTCGCTGCGCTGGCCGGCGGCGAGACGCGCGTGCGCGACCTGCTCGATTCCGACGACACCCGCGTCATGC
TGCAGGCGCTGAAGACCCTCGGCGTCGCGTGGCGCCAGGAAGGCAGCGACTACATCGTGACCGGTTCGGGCGGCAATTTC
CCGGTCAAGGCGGCCGAGTTGTTCATGGGAAATGCCGGCACGGCGATCCGTCCGCTGACGGCCGCGCTCGCGCTGCAGGG
CGGCGACTACAAGCTGTCCGGTGTGCCGCGCATGCACGAACGGCCGATTGGCGATCTCGTGGATGGCCTGCGCCAGGTGG
GCGCGGACATCGGCTATCTCGCCAATGAAGGGTTTCCGCCCTTGCATATCCGTCCCGCGCAGATCCGCATCGATGCGCCG
ATCCGCGTGCGCGGCGATGTGTCGAGCCAGTTCCTGACCGCGCTGCTCATGACGCTGCCGATGGCGCAGGCGGCAAACGG
CAAGATCGAGATCGAAGTGGTCGGCGAACTGATCTCGAAGCCCTATATCGAGATCACGCTCAACCTGCTTGCGCGCTTCG
GCATCAACGTGGAGCGGCAGGGCTGGGAGCGCTTTATCGTCCCGGCCGGCGCGGTGTACCGCTCGCCGGGCGAGATCTAC
GTGGAAGGCGATGCCTCGTCGGCCTCCTATTTCCTGGCGGCCGGCGCGATCGGCGGCGGCCCGGTGCGCGTGGAAGGCGT
CGGCATGAGCAGCATCCAGGGCGACGTGCGTTTTGCCGAGGCGCTCAACCGGATGGGCGCCAATGTCATGGCCGGCGACA
ACTGGATCGAAGTGCGCGGCACCGAGCGCGACGATGGCCGCCTGCATGGCATCGAACTGGACTGCAACCATATTCCCGAT
GCCGCGATGACGCTCGCGGTGGCGGCGCTGTTCGCCGGGGGCACGACCACGCTCACGAATATCGCGAGCTGGCGCGTCAA
GGAAACCGATCGCATCTCGGCCATGGCGACCGAACTGCGCAAGCTCGGCGCGACGGTGGAAGAGGGGGCCGACTACCTGA
AGGTAACGCCGCCCGCGCAGTGGCAGACGCCGGCCGACGGCATTGGCACCTACGATGACCATCGCATGGCGATGTGTTTC
TCGCTGGCTGCATTCGGCCCGCTGCCGGTCCGGATCAATGACCCGGGCTGCGTGGCGAAGACGTTCCCGGACTACTTCGC
GGTGTTCGGCGGCGTTACGCGCTAA

Upstream 100 bases:

>100_bases
GCGAGCAAGACTCGCCTGCAATGGGGCGCCGACCGGGCAGCCGCGGCGAATACTGAACCCTGAACTGGCGCGGCCACGAG
CCGTGCCTAGCGTGAATACC

Downstream 100 bases:

>100_bases
GCGCCGGGGTGCCAGCCTGCACCGGTTCGTGCCGGTGCTCCCGCTTTTCCCGCCGGTCCCAGTAGCGGTCGAAGAAGTAG
TGCGCCACAGTATTGATGGC

Product: 3-phosphoshikimate 1-carboxyvinyltransferase

Products: NA

Alternate protein names: 5-enolpyruvylshikimate-3-phosphate synthase; EPSP synthase; EPSPS [H]

Number of amino acids: Translated: 434; Mature: 434

Protein sequence:

>434_residues
MEHLTLGPLTRAAGTVRLPGSKSISNRVLLLAALAGGETRVRDLLDSDDTRVMLQALKTLGVAWRQEGSDYIVTGSGGNF
PVKAAELFMGNAGTAIRPLTAALALQGGDYKLSGVPRMHERPIGDLVDGLRQVGADIGYLANEGFPPLHIRPAQIRIDAP
IRVRGDVSSQFLTALLMTLPMAQAANGKIEIEVVGELISKPYIEITLNLLARFGINVERQGWERFIVPAGAVYRSPGEIY
VEGDASSASYFLAAGAIGGGPVRVEGVGMSSIQGDVRFAEALNRMGANVMAGDNWIEVRGTERDDGRLHGIELDCNHIPD
AAMTLAVAALFAGGTTTLTNIASWRVKETDRISAMATELRKLGATVEEGADYLKVTPPAQWQTPADGIGTYDDHRMAMCF
SLAAFGPLPVRINDPGCVAKTFPDYFAVFGGVTR

Sequences:

>Translated_434_residues
MEHLTLGPLTRAAGTVRLPGSKSISNRVLLLAALAGGETRVRDLLDSDDTRVMLQALKTLGVAWRQEGSDYIVTGSGGNF
PVKAAELFMGNAGTAIRPLTAALALQGGDYKLSGVPRMHERPIGDLVDGLRQVGADIGYLANEGFPPLHIRPAQIRIDAP
IRVRGDVSSQFLTALLMTLPMAQAANGKIEIEVVGELISKPYIEITLNLLARFGINVERQGWERFIVPAGAVYRSPGEIY
VEGDASSASYFLAAGAIGGGPVRVEGVGMSSIQGDVRFAEALNRMGANVMAGDNWIEVRGTERDDGRLHGIELDCNHIPD
AAMTLAVAALFAGGTTTLTNIASWRVKETDRISAMATELRKLGATVEEGADYLKVTPPAQWQTPADGIGTYDDHRMAMCF
SLAAFGPLPVRINDPGCVAKTFPDYFAVFGGVTR
>Mature_434_residues
MEHLTLGPLTRAAGTVRLPGSKSISNRVLLLAALAGGETRVRDLLDSDDTRVMLQALKTLGVAWRQEGSDYIVTGSGGNF
PVKAAELFMGNAGTAIRPLTAALALQGGDYKLSGVPRMHERPIGDLVDGLRQVGADIGYLANEGFPPLHIRPAQIRIDAP
IRVRGDVSSQFLTALLMTLPMAQAANGKIEIEVVGELISKPYIEITLNLLARFGINVERQGWERFIVPAGAVYRSPGEIY
VEGDASSASYFLAAGAIGGGPVRVEGVGMSSIQGDVRFAEALNRMGANVMAGDNWIEVRGTERDDGRLHGIELDCNHIPD
AAMTLAVAALFAGGTTTLTNIASWRVKETDRISAMATELRKLGATVEEGADYLKVTPPAQWQTPADGIGTYDDHRMAMCF
SLAAFGPLPVRINDPGCVAKTFPDYFAVFGGVTR

Specific function: Aromatic amino acids biosynthesis; shikimate pathway; sixth step. [C]

COG id: COG0128

COG function: function code E; 5-enolpyruvylshikimate-3-phosphate synthase

Gene ontology:

Cell location: Cytoplasm [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the EPSP synthase family [H]

Homologues:

Organism=Escherichia coli, GI1787137, Length=437, Percent_Identity=55.6064073226545, Blast_Score=446, Evalue=1e-126,
Organism=Saccharomyces cerevisiae, GI6320332, Length=451, Percent_Identity=38.5809312638581, Blast_Score=245, Evalue=1e-65,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001986
- InterPro:   IPR006264
- InterPro:   IPR023193
- InterPro:   IPR013792 [H]

Pfam domain/function: PF00275 EPSP_synthase [H]

EC number: =2.5.1.19 [H]

Molecular weight: Translated: 46276; Mature: 46276

Theoretical pI: Translated: 5.49; Mature: 5.49

Prosite motif: PS00104 EPSP_SYNTHASE_1 ; PS00885 EPSP_SYNTHASE_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
3.0 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MEHLTLGPLTRAAGTVRLPGSKSISNRVLLLAALAGGETRVRDLLDSDDTRVMLQALKTL
CCCCCCCCHHHCCCEEECCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHH
GVAWRQEGSDYIVTGSGGNFPVKAAELFMGNAGTAIRPLTAALALQGGDYKLSGVPRMHE
HHHHHCCCCCEEEECCCCCCCCEEHHEEECCCCCHHHHHHHHHEECCCCEEECCCCCHHC
RPIGDLVDGLRQVGADIGYLANEGFPPLHIRPAQIRIDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCHHHHHCCCCCCCEEECCEEEECCCEEEECCCHHHHHHHHHHHHC
MAQAANGKIEIEVVGELISKPYIEITLNLLARFGINVERQGWERFIVPAGAVYRSPGEIY
HHHCCCCEEEEEEEHHHHCCCEEEHHHHHHHHHCCCEECCCCEEEEECCCCEEECCCEEE
VEGDASSASYFLAAGAIGGGPVRVEGVGMSSIQGDVRFAEALNRMGANVMAGDNWIEVRG
EECCCCCCEEEEEECCCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCEEEECCCEEEEEC
TERDDGRLHGIELDCNHIPDAAMTLAVAALFAGGTTTLTNIASWRVKETDRISAMATELR
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHEEECCHHHHHHHHHHHH
KLGATVEEGADYLKVTPPAQWQTPADGIGTYDDHRMAMCFSLAAFGPLPVRINDPGCVAK
HHCCCHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEC
TFPDYFAVFGGVTR
CCHHHHHHHCCCCC
>Mature Secondary Structure
MEHLTLGPLTRAAGTVRLPGSKSISNRVLLLAALAGGETRVRDLLDSDDTRVMLQALKTL
CCCCCCCCHHHCCCEEECCCCCCCCCCEEEEEEECCCHHHHHHHHCCCCHHHHHHHHHHH
GVAWRQEGSDYIVTGSGGNFPVKAAELFMGNAGTAIRPLTAALALQGGDYKLSGVPRMHE
HHHHHCCCCCEEEECCCCCCCCEEHHEEECCCCCHHHHHHHHHEECCCCEEECCCCCHHC
RPIGDLVDGLRQVGADIGYLANEGFPPLHIRPAQIRIDAPIRVRGDVSSQFLTALLMTLP
CCHHHHHHHHHHHCCCHHHHHCCCCCCCEEECCEEEECCCEEEECCCHHHHHHHHHHHHC
MAQAANGKIEIEVVGELISKPYIEITLNLLARFGINVERQGWERFIVPAGAVYRSPGEIY
HHHCCCCEEEEEEEHHHHCCCEEEHHHHHHHHHCCCEECCCCEEEEECCCCEEECCCEEE
VEGDASSASYFLAAGAIGGGPVRVEGVGMSSIQGDVRFAEALNRMGANVMAGDNWIEVRG
EECCCCCCEEEEEECCCCCCCEEEEECCHHHHCCHHHHHHHHHHCCCEEEECCCEEEEEC
TERDDGRLHGIELDCNHIPDAAMTLAVAALFAGGTTTLTNIASWRVKETDRISAMATELR
CCCCCCEEEEEEEECCCCCHHHHHHHHHHHHCCCCHHHHHHHHEEECCHHHHHHHHHHHH
KLGATVEEGADYLKVTPPAQWQTPADGIGTYDDHRMAMCFSLAAFGPLPVRINDPGCVAK
HHCCCHHCCCCEEEECCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCEEEEECCCCCEEC
TFPDYFAVFGGVTR
CCHHHHHHHCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: NA