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The map label for this gene is rutG [H]

Identifier: 73542246

GI number: 73542246

Start: 2805996

End: 2807294

Strand: Reverse

Name: rutG [H]

Synonym: Reut_A2561

Alternate gene names: 73542246

Gene position: 2807294-2805996 (Counterclockwise)

Preceding gene: 73542247

Following gene: 73542245

Centisome position: 73.75

GC content: 62.97

Gene sequence:

>1299_bases
ATGACCAATGGCGAGGACACAGGGTTCCTGCCGAAGTGGCGACTGAAGACGGAAGGGGTCATCGGTCCGGACGAGCGCCT
GCCCACCGGGCAGACGGTACTTGCCGGCATCCAGCACGTGGTGGCGATGTTCGGTTCCACGGCTATCGCGCCGATCCTGA
TGGGATTCAACCCGAACATCGCCATCCTTTTCTCTGGCATCGGCACGCTTATCTTTTTCCTGTGCGTGCGCGGCCGCGTG
CCCAGCTATCTGGGCTCCAGCTTCGCGTTCATCGCCGTCGTGATCGCGGCCACCGGCTATGCGGGCAGCGGACCCAATAC
CAATATCCCGGTCGCGCTGGGCGGCATCATCGCCGCAGGCGCGTTGTACACGGTGATCGGCCTCGTCGTTCAGGCAGTCG
GCTATAGCTGGGTGGAAAAGCTGATGCCGCCTGTGGTCACGGGCGCGATCGTCGCAGCCATCGGACTGAACCTCGCGCCG
GTGGCGGTAAAGGCCGTGAGCGGATCGTCGTTCGATACGTGGGTCGGCTTGCTGACCGTGCTGGCGGTCGGACTGGTGGC
AGTGCGCGCGCCTGGCATGATCGGTCGCCTTCCAGTGCTGATCGGCGGCCTGTTCGGCTACCTGATTTATTTCGTCGGCA
CGAACCTGATGGGCCTGGGCAAGCCAATCGATTTCGCTGGCGTGGCCGCCGCGAACTGGTTCGGCCTGCCGGCGTTCACT
TCGCCGGTATTCGAATTCAGCGCCATGCTGCTGATCGCACCGGTGGCCATCGTGCTGGTCGCAGAGAACCTCGGTCACAT
CAAGGCCATTGGCGTGATGACGGGCCGCAATCTCGATCCGTACATCGGCCGTGCGTTTATTGGCGACGGTGTGGCGACCA
TGCTGTCCGCCAGTGGCGGCGGCACCGGCGTTACCACCTATGCCGAGAACATGGGCGTGATGGCCGTGACCAAGATCTAT
TCGACGCTGATCTTCGTCGTGGCCGCTGCGGTTGCCATCCTGCTCGGGTTCTCGCCGAAGTTCGGTGCGCTGATCCTGAC
CATTCCGGGCCCTGTGATAGGCGGCTTGACCATCGTGGTGTTCGGCTTGATTGCTGCCACGGCAGGCCGTATCTGGGTTC
AGAATCACGTCGACTTTTCCAGCTCGCGCAACCTCATTACAGTGGGCGCGACGCTGACGGTAGCGGCCGGTGACCTGACG
CTCAGGCTCGGTGGTATGACGCTGGGCGGCATTGGCACCGCGACGTTCGGTTGCATCCTGCTTTACCACCTGCTCGGCGA
AGGCAACAAGGAGGCTTAA

Upstream 100 bases:

>100_bases
CCAGGTGGTTTCTCCGGCCGCGCGATCTGTATAACCAGGCCAGGCCTCGCCCTTCCCAATGGGCCAGGGAGAGCCCGGCA
GAACAACAGGGAGCATAACA

Downstream 100 bases:

>100_bases
GCCGGGGCATCCACACTGGCAGTGGGCCCAACGGGCCGCTGCCGGCGCGGGTCAGGGGCCTGGATTACAATGTGCAGGAC
ATTTTCGACCCCGCACCATG

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 432; Mature: 431

Protein sequence:

>432_residues
MTNGEDTGFLPKWRLKTEGVIGPDERLPTGQTVLAGIQHVVAMFGSTAIAPILMGFNPNIAILFSGIGTLIFFLCVRGRV
PSYLGSSFAFIAVVIAATGYAGSGPNTNIPVALGGIIAAGALYTVIGLVVQAVGYSWVEKLMPPVVTGAIVAAIGLNLAP
VAVKAVSGSSFDTWVGLLTVLAVGLVAVRAPGMIGRLPVLIGGLFGYLIYFVGTNLMGLGKPIDFAGVAAANWFGLPAFT
SPVFEFSAMLLIAPVAIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSASGGGTGVTTYAENMGVMAVTKIY
STLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVVFGLIAATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLT
LRLGGMTLGGIGTATFGCILLYHLLGEGNKEA

Sequences:

>Translated_432_residues
MTNGEDTGFLPKWRLKTEGVIGPDERLPTGQTVLAGIQHVVAMFGSTAIAPILMGFNPNIAILFSGIGTLIFFLCVRGRV
PSYLGSSFAFIAVVIAATGYAGSGPNTNIPVALGGIIAAGALYTVIGLVVQAVGYSWVEKLMPPVVTGAIVAAIGLNLAP
VAVKAVSGSSFDTWVGLLTVLAVGLVAVRAPGMIGRLPVLIGGLFGYLIYFVGTNLMGLGKPIDFAGVAAANWFGLPAFT
SPVFEFSAMLLIAPVAIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSASGGGTGVTTYAENMGVMAVTKIY
STLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVVFGLIAATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLT
LRLGGMTLGGIGTATFGCILLYHLLGEGNKEA
>Mature_431_residues
TNGEDTGFLPKWRLKTEGVIGPDERLPTGQTVLAGIQHVVAMFGSTAIAPILMGFNPNIAILFSGIGTLIFFLCVRGRVP
SYLGSSFAFIAVVIAATGYAGSGPNTNIPVALGGIIAAGALYTVIGLVVQAVGYSWVEKLMPPVVTGAIVAAIGLNLAPV
AVKAVSGSSFDTWVGLLTVLAVGLVAVRAPGMIGRLPVLIGGLFGYLIYFVGTNLMGLGKPIDFAGVAAANWFGLPAFTS
PVFEFSAMLLIAPVAIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSASGGGTGVTTYAENMGVMAVTKIYS
TLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVVFGLIAATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLTL
RLGGMTLGGIGTATFGCILLYHLLGEGNKEA

Specific function: May function as a proton-driven pyrimidine uptake system [H]

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Escherichia coli, GI87081818, Length=422, Percent_Identity=65.4028436018957, Blast_Score=536, Evalue=1e-153,
Organism=Escherichia coli, GI1788843, Length=430, Percent_Identity=36.9767441860465, Blast_Score=244, Evalue=1e-65,
Organism=Escherichia coli, GI87082181, Length=399, Percent_Identity=26.8170426065163, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI87082178, Length=381, Percent_Identity=24.4094488188976, Blast_Score=67, Evalue=2e-12,
Organism=Caenorhabditis elegans, GI71993493, Length=202, Percent_Identity=33.1683168316832, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=253, Percent_Identity=26.8774703557312, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=202, Percent_Identity=33.1683168316832, Blast_Score=74, Evalue=2e-13,
Organism=Caenorhabditis elegans, GI17558856, Length=321, Percent_Identity=27.1028037383178, Blast_Score=71, Evalue=1e-12,
Organism=Caenorhabditis elegans, GI17542262, Length=166, Percent_Identity=31.3253012048193, Blast_Score=70, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356175, Length=171, Percent_Identity=32.1637426900585, Blast_Score=71, Evalue=1e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR019918
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 44084; Mature: 43953

Theoretical pI: Translated: 8.97; Mature: 8.97

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.8 %Met     (Translated Protein)
3.2 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.6 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTNGEDTGFLPKWRLKTEGVIGPDERLPTGQTVLAGIQHVVAMFGSTAIAPILMGFNPNI
CCCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCE
AILFSGIGTLIFFLCVRGRVPSYLGSSFAFIAVVIAATGYAGSGPNTNIPVALGGIIAAG
EEEHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
ALYTVIGLVVQAVGYSWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSGSSFDTWVGLLTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHH
LAVGLVAVRAPGMIGRLPVLIGGLFGYLIYFVGTNLMGLGKPIDFAGVAAANWFGLPAFT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHCCCCCCHHH
SPVFEFSAMLLIAPVAIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSASGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCHHHHHHCCCC
GTGVTTYAENMGVMAVTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVV
CCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHH
FGLIAATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLTLRLGGMTLGGIGTATFGCIL
HHHHHHHCCCEEEEECCCCCCCCCEEEECCEEEEEECCEEEEECCEEECCHHHHHHHHHH
LYHLLGEGNKEA
HHHHHCCCCCCC
>Mature Secondary Structure 
TNGEDTGFLPKWRLKTEGVIGPDERLPTGQTVLAGIQHVVAMFGSTAIAPILMGFNPNI
CCCCCCCCCCCCEECCCCCCCCCCCCCCCHHHHHHHHHHHHHHCCHHHHHHHCCCCCCE
AILFSGIGTLIFFLCVRGRVPSYLGSSFAFIAVVIAATGYAGSGPNTNIPVALGGIIAAG
EEEHHHHHHHHHHHHHHCCCCHHHCCHHHHHHHHHHHCCCCCCCCCCCCCEEHHHHHHHH
ALYTVIGLVVQAVGYSWVEKLMPPVVTGAIVAAIGLNLAPVAVKAVSGSSFDTWVGLLTV
HHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHCCCCCHHEEEEECCCCHHHHHHHHHH
LAVGLVAVRAPGMIGRLPVLIGGLFGYLIYFVGTNLMGLGKPIDFAGVAAANWFGLPAFT
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHCCHHCCCCCCCHHHHHHHCCCCCCHHH
SPVFEFSAMLLIAPVAIVLVAENLGHIKAIGVMTGRNLDPYIGRAFIGDGVATMLSASGG
HHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEEEECCCCCHHHHHHHHCCCHHHHHHCCCC
GTGVTTYAENMGVMAVTKIYSTLIFVVAAAVAILLGFSPKFGALILTIPGPVIGGLTIVV
CCCEEHHHHCCCHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCEEEEEECCHHHHHHHHHH
FGLIAATAGRIWVQNHVDFSSSRNLITVGATLTVAAGDLTLRLGGMTLGGIGTATFGCIL
HHHHHHHCCCEEEEECCCCCCCCCEEEECCEEEEEECCEEEEECCEEECCHHHHHHHHHH
LYHLLGEGNKEA
HHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8905232; 9278503 [H]