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The map label for this gene is qor [H]

Identifier: 73542188

GI number: 73542188

Start: 2743610

End: 2744593

Strand: Reverse

Name: qor [H]

Synonym: Reut_A2503

Alternate gene names: 73542188

Gene position: 2744593-2743610 (Counterclockwise)

Preceding gene: 73542189

Following gene: 73542181

Centisome position: 72.1

GC content: 64.33

Gene sequence:

>984_bases
ATGCCAATGACCAAAGCCATCCGGATCGAACAGACCGGCGGACCGGAAGTGATGCAGTGGGTCGATGTGGAAGTGGGCGA
GCCCGGCCCGGGCGAAGTTCGTGTGCGTCATGAAGCGGTGGGCCTGAACTTTATCGACGTCTATTTCCGCACCGGCCTCT
ACAAGCAGCCGCTGCCTGGTGGGCTGGGCATGGAAGGCGCGGGCGTGGTCGAAGCGGTGGGCGAGGGCGTGGCACACCTG
AGCGTGGGCGACCGCGTGGCCTACGCTGGCCGCCCGAACGGCGCCTATTCGCAGGTGCGTGTGATGCCGGCCGATATCGT
GGTGCGCCTGCCCGAATCGATCTCGTTCGAGCAGGGCGCGGCGATGATGCTGCAGGGTCTGACCGTGCAGTACCTGATTC
GCGACAGCTATCGCGTTCAGGCTGGCGACACGGTGCTGCTGCATGCCGCGGCCGGCGGCGTCGGGCTGATCGCTTGCCAA
TGGCTGAAGGCGCTTGGCGTCACGGTAATCGGCACGGTCGGCAGCGACGAGAAGGCGGAGCTGGCGCGCGCGCATGGCTG
CACGCATACCGTCGTCTACACGCGTGAATCGTTCGTGGATCGGGTAAAGGAAATCACTGGCGGCAAGGGCGTGCCGGCCG
TGTATGACTCGATCGGCGCGGACACCTTCCGTGGCTCGCTGGATTGCCTGGCGCCGCGTGGGACGATGGTGAGCTTCGGG
AGTGCTTCCGGACCGGTGCCCCCGTTTGATATCTCGGTGCTTGGCAACAAGGGTTCACTGCGGCTGACGCGGCCAACGTT
GATGACGTATGTGGTACATCGTGAATTGCTGGAGCCGATGGTTGCGGATCTGTTTGATGTGGTCAGCAGTGGCAAGGTGA
AGATCGATGTGCGGCAGCGGTATGCGCTGGCGGATGTGGCGCAGGCGCACCGTGATCTCGAATCGCGCAAGACGACCGGA
TCGACCATTCTGCTGCCGCGCTGA

Upstream 100 bases:

>100_bases
TGCCGTGCGCGACCAACGTGGCCACGGCCGACCTGCTGATCGCCGAGCTGAGCCGCGTCGAAGCGCAGCCCTGAACGAAA
CCCATATCGAGACAGAAGAC

Downstream 100 bases:

>100_bases
AGCATCACGCATTGCATGAGAAAGCCCCCGGACGGCATGCCGTCCGGGGGCTTTTCCGTCCGGGCGCTCAGCGCGCGCGG
ACGGTGGTGGCAGTCGCGCG

Product: zinc-containing alcohol dehydrogenase superfamily protein

Products: NA

Alternate protein names: NADPH:quinone reductase [H]

Number of amino acids: Translated: 327; Mature: 326

Protein sequence:

>327_residues
MPMTKAIRIEQTGGPEVMQWVDVEVGEPGPGEVRVRHEAVGLNFIDVYFRTGLYKQPLPGGLGMEGAGVVEAVGEGVAHL
SVGDRVAYAGRPNGAYSQVRVMPADIVVRLPESISFEQGAAMMLQGLTVQYLIRDSYRVQAGDTVLLHAAAGGVGLIACQ
WLKALGVTVIGTVGSDEKAELARAHGCTHTVVYTRESFVDRVKEITGGKGVPAVYDSIGADTFRGSLDCLAPRGTMVSFG
SASGPVPPFDISVLGNKGSLRLTRPTLMTYVVHRELLEPMVADLFDVVSSGKVKIDVRQRYALADVAQAHRDLESRKTTG
STILLPR

Sequences:

>Translated_327_residues
MPMTKAIRIEQTGGPEVMQWVDVEVGEPGPGEVRVRHEAVGLNFIDVYFRTGLYKQPLPGGLGMEGAGVVEAVGEGVAHL
SVGDRVAYAGRPNGAYSQVRVMPADIVVRLPESISFEQGAAMMLQGLTVQYLIRDSYRVQAGDTVLLHAAAGGVGLIACQ
WLKALGVTVIGTVGSDEKAELARAHGCTHTVVYTRESFVDRVKEITGGKGVPAVYDSIGADTFRGSLDCLAPRGTMVSFG
SASGPVPPFDISVLGNKGSLRLTRPTLMTYVVHRELLEPMVADLFDVVSSGKVKIDVRQRYALADVAQAHRDLESRKTTG
STILLPR
>Mature_326_residues
PMTKAIRIEQTGGPEVMQWVDVEVGEPGPGEVRVRHEAVGLNFIDVYFRTGLYKQPLPGGLGMEGAGVVEAVGEGVAHLS
VGDRVAYAGRPNGAYSQVRVMPADIVVRLPESISFEQGAAMMLQGLTVQYLIRDSYRVQAGDTVLLHAAAGGVGLIACQW
LKALGVTVIGTVGSDEKAELARAHGCTHTVVYTRESFVDRVKEITGGKGVPAVYDSIGADTFRGSLDCLAPRGTMVSFGS
ASGPVPPFDISVLGNKGSLRLTRPTLMTYVVHRELLEPMVADLFDVVSSGKVKIDVRQRYALADVAQAHRDLESRKTTGS
TILLPR

Specific function: Unknown

COG id: COG0604

COG function: function code CR; NADPH:quinone reductase and related Zn-dependent oxidoreductases

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily [H]

Homologues:

Organism=Homo sapiens, GI18379349, Length=314, Percent_Identity=33.4394904458599, Blast_Score=147, Evalue=1e-35,
Organism=Homo sapiens, GI194239674, Length=329, Percent_Identity=31.306990881459, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI13236495, Length=329, Percent_Identity=31.306990881459, Blast_Score=142, Evalue=4e-34,
Organism=Homo sapiens, GI194239676, Length=328, Percent_Identity=29.8780487804878, Blast_Score=130, Evalue=2e-30,
Organism=Homo sapiens, GI22538446, Length=336, Percent_Identity=30.3571428571429, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI22538444, Length=336, Percent_Identity=30.3571428571429, Blast_Score=126, Evalue=3e-29,
Organism=Homo sapiens, GI24308257, Length=343, Percent_Identity=28.8629737609329, Blast_Score=109, Evalue=3e-24,
Organism=Homo sapiens, GI28557745, Length=234, Percent_Identity=33.7606837606838, Blast_Score=100, Evalue=2e-21,
Organism=Homo sapiens, GI197927207, Length=190, Percent_Identity=30, Blast_Score=75, Evalue=9e-14,
Organism=Homo sapiens, GI41872631, Length=223, Percent_Identity=30.4932735426009, Blast_Score=70, Evalue=3e-12,
Organism=Escherichia coli, GI1790485, Length=327, Percent_Identity=50.7645259938838, Blast_Score=328, Evalue=4e-91,
Organism=Escherichia coli, GI1787863, Length=354, Percent_Identity=24.5762711864407, Blast_Score=62, Evalue=5e-11,
Organism=Caenorhabditis elegans, GI17507255, Length=239, Percent_Identity=30.9623430962343, Blast_Score=105, Evalue=2e-23,
Organism=Caenorhabditis elegans, GI17562878, Length=199, Percent_Identity=31.6582914572864, Blast_Score=71, Evalue=6e-13,
Organism=Caenorhabditis elegans, GI17556000, Length=267, Percent_Identity=27.3408239700375, Blast_Score=67, Evalue=1e-11,
Organism=Saccharomyces cerevisiae, GI6319520, Length=324, Percent_Identity=38.8888888888889, Blast_Score=215, Evalue=8e-57,
Organism=Saccharomyces cerevisiae, GI6319955, Length=322, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=8e-12,
Organism=Saccharomyces cerevisiae, GI6322619, Length=322, Percent_Identity=26.0869565217391, Blast_Score=66, Evalue=9e-12,
Organism=Saccharomyces cerevisiae, GI6324486, Length=267, Percent_Identity=26.5917602996255, Blast_Score=66, Evalue=9e-12,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR013149
- InterPro:   IPR013154
- InterPro:   IPR002085
- InterPro:   IPR011032
- InterPro:   IPR016040
- InterPro:   IPR002364 [H]

Pfam domain/function: PF08240 ADH_N; PF00107 ADH_zinc_N [H]

EC number: =1.6.5.5 [H]

Molecular weight: Translated: 34917; Mature: 34785

Theoretical pI: Translated: 6.88; Mature: 6.88

Prosite motif: PS01162 QOR_ZETA_CRYSTAL

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.9 %Cys     (Translated Protein)
3.1 %Met     (Translated Protein)
4.0 %Cys+Met (Translated Protein)
0.9 %Cys     (Mature Protein)
2.8 %Met     (Mature Protein)
3.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPMTKAIRIEQTGGPEVMQWVDVEVGEPGPGEVRVRHEAVGLNFIDVYFRTGLYKQPLPG
CCCCCEEEEECCCCHHEEEEEEEECCCCCCCCEEEEEEECCCCCEEHHHHCCCCCCCCCC
GLGMEGAGVVEAVGEGVAHLSVGDRVAYAGRPNGAYSQVRVMPADIVVRLPESISFEQGA
CCCCCCCHHHHHHCCCEEEEECCCEEEECCCCCCCCCEEEEECHHEEEECCCCCCCCCCH
AMMLQGLTVQYLIRDSYRVQAGDTVLLHAAAGGVGLIACQWLKALGVTVIGTVGSDEKAE
HHHHHCCEEEEEECCCEEEECCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCHHHH
LARAHGCTHTVVYTRESFVDRVKEITGGKGVPAVYDSIGADTFRGSLDCLAPRGTMVSFG
HHHHCCCEEEEEEEHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCCCCEEECCCCCEEEEC
SASGPVPPFDISVLGNKGSLRLTRPTLMTYVVHRELLEPMVADLFDVVSSGKVKIDVRQR
CCCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHH
YALADVAQAHRDLESRKTTGSTILLPR
HHHHHHHHHHHHHHHHCCCCCEEEECC
>Mature Secondary Structure 
PMTKAIRIEQTGGPEVMQWVDVEVGEPGPGEVRVRHEAVGLNFIDVYFRTGLYKQPLPG
CCCCEEEEECCCCHHEEEEEEEECCCCCCCCEEEEEEECCCCCEEHHHHCCCCCCCCCC
GLGMEGAGVVEAVGEGVAHLSVGDRVAYAGRPNGAYSQVRVMPADIVVRLPESISFEQGA
CCCCCCCHHHHHHCCCEEEEECCCEEEECCCCCCCCCEEEEECHHEEEECCCCCCCCCCH
AMMLQGLTVQYLIRDSYRVQAGDTVLLHAAAGGVGLIACQWLKALGVTVIGTVGSDEKAE
HHHHHCCEEEEEECCCEEEECCCEEEEEECCCCHHHHHHHHHHHCCEEEEEECCCCHHHH
LARAHGCTHTVVYTRESFVDRVKEITGGKGVPAVYDSIGADTFRGSLDCLAPRGTMVSFG
HHHHCCCEEEEEEEHHHHHHHHHHHCCCCCCCHHHHHCCCHHHCCCCEEECCCCCEEEEC
SASGPVPPFDISVLGNKGSLRLTRPTLMTYVVHRELLEPMVADLFDVVSSGKVKIDVRQR
CCCCCCCCCEEEEECCCCCEEEECHHHHHHHHHHHHHHHHHHHHHHHHCCCEEEEEHHHH
YALADVAQAHRDLESRKTTGSTILLPR
HHHHHHHHHHHHHHHHCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10984043 [H]