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The map label for this gene is ygfU [H]

Identifier: 73542122

GI number: 73542122

Start: 2671108

End: 2672556

Strand: Direct

Name: ygfU [H]

Synonym: Reut_A2436

Alternate gene names: 73542122

Gene position: 2671108-2672556 (Clockwise)

Preceding gene: 73542121

Following gene: 73542123

Centisome position: 70.17

GC content: 65.01

Gene sequence:

>1449_bases
ATGCCAGTGTTCCCATCAAACCAAAGGAGAGGAGACGCACCAATGACTTCCGCAAGCACCACGGTCCCCACGGACCTGAC
TAACGAGCGTCTGCCTTCCGGGCGTCTGCTCGCGCTCGGGCTGCAGCACGTGCTGGTGATGTATGCCGGCACCGTGGCGG
TCCCCCTGATCGTCGGTGGCGCCCTGAAGCTGCCCAAGGACCAGCTGGCTTTCCTGATCAACGCCGACCTGTTCGCCGCG
GGCCTCGCCACGCTGATCCAGGCCTTCGGCTTCTGGAAGTTCGGCATCCGCATGCCCGTGATGATGGGCGTGACCTTTGC
CTCGGTGGCACCGATGATCGCCATCGGCACCGACCCGAACGTCGGCCTGCTCGGCATCTACGGCGCGGTGATCGCGTCAG
GAGTGTTCGGCATCCTGGTTGCGCCGATGATGGGTCGCATGCTCGGGCTGTTTCCGCCCGTGGTGACGGGCACGGTGATC
ACGCTGATCGGCGTGTCGCTGATGCGCGTGGGCATCAACTGGGCAGCCGGCGGCCAGCCCACCACGCGCGCCGTGATCGA
CGGTGTGGTGAAGGAAGTGCCCAACCTCGCCTACGGTGACCTGGCCAACCTTGGCATCGCCGGGCTCACGCTCGCGGTCA
TCCTGCTGCTGACCAAATATGGCCGCGGCCTGGTGGCCAACTGCGCGGTGCTGCTCGGCATCATCGCGGGCACGTTCGTG
GCCATGGCCATGGGCAAGGTGTCGTTCGAAGGCCTGAATGAAGCGAGCTTCGTCGCCGTCATCACCCCGCTGCACTTCGG
CATCCCGACCTTTGAACTCAGCGCGATCCTGTCGATGTGCATCGTCATGCTGATCACGCTGGTGGAATCCACCGGCATGT
TCCTGGCCCTGTCGGACATCACCGGCAAGAAGCTGAGCAATGAAGACCTGACCCGTGGCCTGCGCGCGGACGGCCTGGGC
ACGGTAATCGGCGGTCTGTTCAACACCTTCCCCTACACCTCGTTCTCGCAGAACGTGGGCCTGGTGACCGTGACCGGCGT
GCGCTCGCGCTACGTGGCGGCAGCCGGCGGCATCATCCTGATCGCGTTCGGCCTGTTCCCGAAGATGGCCCACGTGGTCG
CCTCGGTGCCGCAGTTTGTGCTCGGCGGTGCCGGCATCGTGATGTTCGGCATGGTCGCCGCCACGGGCATCCGCATCCTC
GGCAGCTGCGATTTCAACCGCAACCGCCACAACCTGTTCATCGTCGCCATCTCGATCGGCTTCGGCATGATCCCGACGCT
GGCGCCGACGTTCTTCCAATACCTGCCGAAGTGGACGGTCCCGTTCACCCACAGCGGGATCGTGCTCGGCACCATCGTGG
CCGTGGCGCTGAACCTCTTCTACAACGGCATCCAGTCGCGCGAAGAGGCCATGCGCAACGCCGCCGCGAACACGCACGGC
ACGGAGTAA

Upstream 100 bases:

>100_bases
GTGTTCCCGCCGGCATCACACCGAACGAGGCCTGGCTGCACTGCCCATGACAGCGTCCTGAAGGATGCGGCGGCGGTGCT
GTCCCAAAAGGAGGCCACGG

Downstream 100 bases:

>100_bases
CCGCGGTTCCCGGCAGCCTCCTCGCAAGACGGCGCTGCCGGTGCCCTGAAGCAGAAACGAACCATGACAGACAAGAACTA
TCCACGCGATCTCATCGGCT

Product: xanthine/uracil permease

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 482; Mature: 481

Protein sequence:

>482_residues
MPVFPSNQRRGDAPMTSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLINADLFAA
GLATLIQAFGFWKFGIRMPVMMGVTFASVAPMIAIGTDPNVGLLGIYGAVIASGVFGILVAPMMGRMLGLFPPVVTGTVI
TLIGVSLMRVGINWAAGGQPTTRAVIDGVVKEVPNLAYGDLANLGIAGLTLAVILLLTKYGRGLVANCAVLLGIIAGTFV
AMAMGKVSFEGLNEASFVAVITPLHFGIPTFELSAILSMCIVMLITLVESTGMFLALSDITGKKLSNEDLTRGLRADGLG
TVIGGLFNTFPYTSFSQNVGLVTVTGVRSRYVAAAGGIILIAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRIL
GSCDFNRNRHNLFIVAISIGFGMIPTLAPTFFQYLPKWTVPFTHSGIVLGTIVAVALNLFYNGIQSREEAMRNAAANTHG
TE

Sequences:

>Translated_482_residues
MPVFPSNQRRGDAPMTSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLINADLFAA
GLATLIQAFGFWKFGIRMPVMMGVTFASVAPMIAIGTDPNVGLLGIYGAVIASGVFGILVAPMMGRMLGLFPPVVTGTVI
TLIGVSLMRVGINWAAGGQPTTRAVIDGVVKEVPNLAYGDLANLGIAGLTLAVILLLTKYGRGLVANCAVLLGIIAGTFV
AMAMGKVSFEGLNEASFVAVITPLHFGIPTFELSAILSMCIVMLITLVESTGMFLALSDITGKKLSNEDLTRGLRADGLG
TVIGGLFNTFPYTSFSQNVGLVTVTGVRSRYVAAAGGIILIAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRIL
GSCDFNRNRHNLFIVAISIGFGMIPTLAPTFFQYLPKWTVPFTHSGIVLGTIVAVALNLFYNGIQSREEAMRNAAANTHG
TE
>Mature_481_residues
PVFPSNQRRGDAPMTSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGGALKLPKDQLAFLINADLFAAG
LATLIQAFGFWKFGIRMPVMMGVTFASVAPMIAIGTDPNVGLLGIYGAVIASGVFGILVAPMMGRMLGLFPPVVTGTVIT
LIGVSLMRVGINWAAGGQPTTRAVIDGVVKEVPNLAYGDLANLGIAGLTLAVILLLTKYGRGLVANCAVLLGIIAGTFVA
MAMGKVSFEGLNEASFVAVITPLHFGIPTFELSAILSMCIVMLITLVESTGMFLALSDITGKKLSNEDLTRGLRADGLGT
VIGGLFNTFPYTSFSQNVGLVTVTGVRSRYVAAAGGIILIAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRILG
SCDFNRNRHNLFIVAISIGFGMIPTLAPTFFQYLPKWTVPFTHSGIVLGTIVAVALNLFYNGIQSREEAMRNAAANTHGT
E

Specific function: Unknown

COG id: COG2233

COG function: function code F; Xanthine/uracil permeases

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the xanthine/uracil permease family. Nucleobase:cation symporter-2 (NCS2) (TC 2.A.40) subfamily [H]

Homologues:

Organism=Homo sapiens, GI44680145, Length=457, Percent_Identity=26.4770240700219, Blast_Score=102, Evalue=1e-21,
Organism=Homo sapiens, GI44680148, Length=184, Percent_Identity=30.9782608695652, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI40316845, Length=184, Percent_Identity=30.9782608695652, Blast_Score=84, Evalue=2e-16,
Organism=Homo sapiens, GI44680143, Length=171, Percent_Identity=32.7485380116959, Blast_Score=83, Evalue=6e-16,
Organism=Escherichia coli, GI87082181, Length=463, Percent_Identity=53.7796976241901, Blast_Score=486, Evalue=1e-139,
Organism=Escherichia coli, GI1790087, Length=447, Percent_Identity=31.5436241610738, Blast_Score=188, Evalue=6e-49,
Organism=Escherichia coli, GI87082178, Length=460, Percent_Identity=27.6086956521739, Blast_Score=145, Evalue=6e-36,
Organism=Escherichia coli, GI87081818, Length=439, Percent_Identity=28.246013667426, Blast_Score=120, Evalue=2e-28,
Organism=Escherichia coli, GI1788843, Length=404, Percent_Identity=27.7227722772277, Blast_Score=118, Evalue=1e-27,
Organism=Caenorhabditis elegans, GI17558856, Length=447, Percent_Identity=24.8322147651007, Blast_Score=92, Evalue=8e-19,
Organism=Caenorhabditis elegans, GI71993493, Length=490, Percent_Identity=21.6326530612245, Blast_Score=76, Evalue=4e-14,
Organism=Caenorhabditis elegans, GI17541904, Length=421, Percent_Identity=21.8527315914489, Blast_Score=73, Evalue=3e-13,
Organism=Caenorhabditis elegans, GI17542260, Length=239, Percent_Identity=23.8493723849372, Blast_Score=71, Evalue=2e-12,
Organism=Drosophila melanogaster, GI21356175, Length=442, Percent_Identity=25.7918552036199, Blast_Score=101, Evalue=1e-21,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR017588
- InterPro:   IPR006042
- InterPro:   IPR006043 [H]

Pfam domain/function: PF00860 Xan_ur_permease [H]

EC number: NA

Molecular weight: Translated: 50396; Mature: 50264

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS01116 XANTH_URACIL_PERMASE

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
4.4 %Met     (Translated Protein)
5.0 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
4.2 %Met     (Mature Protein)
4.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure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CC
>Mature Secondary Structure 
PVFPSNQRRGDAPMTSASTTVPTDLTNERLPSGRLLALGLQHVLVMYAGTVAVPLIVGG
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHCC
ALKLPKDQLAFLINADLFAAGLATLIQAFGFWKFGIRMPVMMGVTFASVAPMIAIGTDPN
CCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCEEEECCCCC
VGLLGIYGAVIASGVFGILVAPMMGRMLGLFPPVVTGTVITLIGVSLMRVGINWAAGGQP
CCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHCCCCCCCCCC
TTRAVIDGVVKEVPNLAYGDLANLGIAGLTLAVILLLTKYGRGLVANCAVLLGIIAGTFV
HHHHHHHHHHHHCCCCCCCCHHHCCHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHHHH
AMAMGKVSFEGLNEASFVAVITPLHFGIPTFELSAILSMCIVMLITLVESTGMFLALSDI
HHHHHHHHHCCCCCCCEEEEEEHHHCCCCHHHHHHHHHHHHHHHHHHHHCCCCEEEEECC
TGKKLSNEDLTRGLRADGLGTVIGGLFNTFPYTSFSQNVGLVTVTGVRSRYVAAAGGIIL
CCCCCCCHHHHCCCCCCCHHHHHHHHHHHCCCCCCCCCCCEEEEECCHHHHHHHCCCHHH
IAFGLFPKMAHVVASVPQFVLGGAGIVMFGMVAATGIRILGSCDFNRNRHNLFIVAISIG
HHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHEEECCCCCCCCCEEEEEEEECC
FGMIPTLAPTFFQYLPKWTVPFTHSGIVLGTIVAVALNLFYNGIQSREEAMRNAAANTHG
CCCHHHHHHHHHHHCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCC
TE
CC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 9278503 [H]