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The map label for this gene is desA [H]

Identifier: 73542116

GI number: 73542116

Start: 2663984

End: 2665126

Strand: Direct

Name: desA [H]

Synonym: Reut_A2430

Alternate gene names: 73542116

Gene position: 2663984-2665126 (Clockwise)

Preceding gene: 73542115

Following gene: 73542117

Centisome position: 69.98

GC content: 66.58

Gene sequence:

>1143_bases
ATGACCACCACCGCTGCCACGCATCCCGAGGTACCGCTGCACGCACCGGCGCCTGCCAACCAGCCGTTTCCCGAACCGAT
TTCCCCAGACCAGCCGCTGCCATCCCGCAAAATCATCCGCGGCTGGCTGATTCCGCTAGGCCAGCGCAGCACGCCGCGCG
CGCTGGCGCTGTTCGCCTTCGACTACCTGCTGTTCGCGGCCACGCTGGCGGGCGTCGTGCTGGCCCCGCACTGGGCCGCC
AAGGTGGGCCTCGGCGTAGTGGCGGGCCTGATCATCGCGCGCCTGTTCATCATCGGCCACGACGCCTGCCACCAGAGCCT
GACGCCGCGCCGCGGCCTGAACAAATGGCTGGGCCGGCTGACGTTCCTGCCGTCGCTGACGCCCTACAGCCTGTGGGAAG
TCGGCCACAACGTGGTCCACCACGGCTACACCAACCTGAAGGGCTTCGACTTCGTCTGGGCGCCGTATTCGCTCGAAGAG
TTCCAGGCGCTGCCGCGCTGGCGCCGCGTGATGGAGCGCATCTACCGCACCGGCTTCGGTCCAGGCCTGTACTACCTGGT
CGAGATCTGGTGGTGCAAGCTGTTCTTCCCGAACAAGCGCCAGATGGCCACGCGCCGTCCGATCTTCATGGCCGATTGCA
CGCTGGTGGCCACGTTCGGCGCCGCGTGGATCGGTGCGCTGATCTGGGCCGCTTTTGCCACCGGGCAATCGGCATGGATG
ATGGTCGGCGCCGGCTTCGTGCTGCCTTTCCTGGTCTGGAACGTGACCGTCGGCTTCGTGCTGTACGTGCACCACACCCA
CACCAGCGTGGCGTGGTACGACACCAAGTCGATGTGGGCCAAGGCCCAGCCGTTCGTCTCGACGACCGTGCACCTGCGTT
TCCGCCATGGCATCGGCGCCGCGCTGCATCACATCATGGAACACACCGCACACCACGTGGACATGAGCGTGCCGCTGTAC
CGCCTGAAGCGCGCGCAGGCGCTGCTCGAACATGCGCTGCCGGGCCGCATCATCATCGAGAATTTCTCGTGGCGCTGGTA
CTTCGACACCGCACGCCGTTGCAAGCTGTACGACTTCAAGGCCCTGTGCTGGACCGACTTCCGCGGTCGCCAGACCAGCG
AGCAGTCCCCCGTGCCGGCCTGA

Upstream 100 bases:

>100_bases
ACGGTGATCAAGACTCGTAACGGCAAAGCCCTCTAACCTTTGCGGTTCCGTTGCAGGCCTTGCGAGGCCGACCCGCAACG
CCAGCAACCTGAAGGTTTCC

Downstream 100 bases:

>100_bases
CACGGCACATTTTCCCGGGCGGTGGACGCTCACCGCCCCCGCCGCTATAATCGCGGCTTCCATTGGGGAGTAGCCGCCCT
GCTCTCACCGCGCCGCGCAA

Product: Fatty acid desaturase

Products: NA

Alternate protein names: Delta(12)-desaturase [H]

Number of amino acids: Translated: 380; Mature: 379

Protein sequence:

>380_residues
MTTTAATHPEVPLHAPAPANQPFPEPISPDQPLPSRKIIRGWLIPLGQRSTPRALALFAFDYLLFAATLAGVVLAPHWAA
KVGLGVVAGLIIARLFIIGHDACHQSLTPRRGLNKWLGRLTFLPSLTPYSLWEVGHNVVHHGYTNLKGFDFVWAPYSLEE
FQALPRWRRVMERIYRTGFGPGLYYLVEIWWCKLFFPNKRQMATRRPIFMADCTLVATFGAAWIGALIWAAFATGQSAWM
MVGAGFVLPFLVWNVTVGFVLYVHHTHTSVAWYDTKSMWAKAQPFVSTTVHLRFRHGIGAALHHIMEHTAHHVDMSVPLY
RLKRAQALLEHALPGRIIIENFSWRWYFDTARRCKLYDFKALCWTDFRGRQTSEQSPVPA

Sequences:

>Translated_380_residues
MTTTAATHPEVPLHAPAPANQPFPEPISPDQPLPSRKIIRGWLIPLGQRSTPRALALFAFDYLLFAATLAGVVLAPHWAA
KVGLGVVAGLIIARLFIIGHDACHQSLTPRRGLNKWLGRLTFLPSLTPYSLWEVGHNVVHHGYTNLKGFDFVWAPYSLEE
FQALPRWRRVMERIYRTGFGPGLYYLVEIWWCKLFFPNKRQMATRRPIFMADCTLVATFGAAWIGALIWAAFATGQSAWM
MVGAGFVLPFLVWNVTVGFVLYVHHTHTSVAWYDTKSMWAKAQPFVSTTVHLRFRHGIGAALHHIMEHTAHHVDMSVPLY
RLKRAQALLEHALPGRIIIENFSWRWYFDTARRCKLYDFKALCWTDFRGRQTSEQSPVPA
>Mature_379_residues
TTTAATHPEVPLHAPAPANQPFPEPISPDQPLPSRKIIRGWLIPLGQRSTPRALALFAFDYLLFAATLAGVVLAPHWAAK
VGLGVVAGLIIARLFIIGHDACHQSLTPRRGLNKWLGRLTFLPSLTPYSLWEVGHNVVHHGYTNLKGFDFVWAPYSLEEF
QALPRWRRVMERIYRTGFGPGLYYLVEIWWCKLFFPNKRQMATRRPIFMADCTLVATFGAAWIGALIWAAFATGQSAWMM
VGAGFVLPFLVWNVTVGFVLYVHHTHTSVAWYDTKSMWAKAQPFVSTTVHLRFRHGIGAALHHIMEHTAHHVDMSVPLYR
LKRAQALLEHALPGRIIIENFSWRWYFDTARRCKLYDFKALCWTDFRGRQTSEQSPVPA

Specific function: Can introduce a second cis double bond at the Delta(12) position of fatty acid bound to membranes glycerolipids. This enzyme is involved in chilling tolerance because the phase transition temperature of lipids of cellular membranes depends on the degree o

COG id: COG3239

COG function: function code I; Fatty acid desaturase

Gene ontology:

Cell location: Cell membrane; Multi-pass membrane protein (Potential) [H]

Metaboloic importance: NA

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fatty acid desaturase family [H]

Homologues:

Organism=Caenorhabditis elegans, GI71999459, Length=264, Percent_Identity=23.1060606060606, Blast_Score=65, Evalue=8e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR005804 [H]

Pfam domain/function: PF00487 FA_desaturase [H]

EC number: NA

Molecular weight: Translated: 43235; Mature: 43104

Theoretical pI: Translated: 10.29; Mature: 10.29

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.4 %Met     (Translated Protein)
3.7 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTTTAATHPEVPLHAPAPANQPFPEPISPDQPLPSRKIIRGWLIPLGQRSTPRALALFAF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
DYLLFAATLAGVVLAPHWAAKVGLGVVAGLIIARLFIIGHDACHQSLTPRRGLNKWLGRL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHH
TFLPSLTPYSLWEVGHNVVHHGYTNLKGFDFVWAPYSLEEFQALPRWRRVMERIYRTGFG
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
PGLYYLVEIWWCKLFFPNKRQMATRRPIFMADCTLVATFGAAWIGALIWAAFATGQSAWM
CHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MVGAGFVLPFLVWNVTVGFVLYVHHTHTSVAWYDTKSMWAKAQPFVSTTVHLRFRHGIGA
HHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEECHHHHHHCCCCCEEEEEEEEHHHHHH
ALHHIMEHTAHHVDMSVPLYRLKRAQALLEHALPGRIIIENFSWRWYFDTARRCKLYDFK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCEEEECH
ALCWTDFRGRQTSEQSPVPA
HHEEECCCCCCCCCCCCCCC
>Mature Secondary Structure 
TTTAATHPEVPLHAPAPANQPFPEPISPDQPLPSRKIIRGWLIPLGQRSTPRALALFAF
CCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHH
DYLLFAATLAGVVLAPHWAAKVGLGVVAGLIIARLFIIGHDACHQSLTPRRGLNKWLGRL
HHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCHHHHHCCCCHHHHHHHHHHH
TFLPSLTPYSLWEVGHNVVHHGYTNLKGFDFVWAPYSLEEFQALPRWRRVMERIYRTGFG
HHCCCCCCHHHHHHHHHHHHCCCCCCCCCEEEECCCCHHHHHHHHHHHHHHHHHHHCCCC
PGLYYLVEIWWCKLFFPNKRQMATRRPIFMADCTLVATFGAAWIGALIWAAFATGQSAWM
CHHHHHHHHHHHHHCCCCCHHHHHCCCEEEEHHHHHHHHHHHHHHHHHHHHHHCCCCHHH
MVGAGFVLPFLVWNVTVGFVLYVHHTHTSVAWYDTKSMWAKAQPFVSTTVHLRFRHGIGA
HHHHHHHHHHHHHHHHHHHEEEEEECCCEEEEEECHHHHHHCCCCCEEEEEEEEHHHHHH
ALHHIMEHTAHHVDMSVPLYRLKRAQALLEHALPGRIIIENFSWRWYFDTARRCKLYDFK
HHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHCCCCEEEEECCCEEEEECCCCCCEEEECH
ALCWTDFRGRQTSEQSPVPA
HHEEECCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: NA