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The map label for this gene is add [H]

Identifier: 73542114

GI number: 73542114

Start: 2661370

End: 2662425

Strand: Direct

Name: add [H]

Synonym: Reut_A2428

Alternate gene names: 73542114

Gene position: 2661370-2662425 (Clockwise)

Preceding gene: 73542113

Following gene: 73542115

Centisome position: 69.92

GC content: 64.39

Gene sequence:

>1056_bases
ATGACCATCGATGCCGCGCTGGCGGACAAGATCCGCCGTACTCCCAAGGCAGAACTGCACGTGCATATCGAAGGCACGCT
CGAACCCGAGCTGATCTTCCGGCTGGCCCAGCGCAACCACGTGAACCTGCCCTACCCCAGCGTCGAGGCTCTGCGCGCGG
CCTATGCGTTCACCGACCTGCAGTCGTTCCTGGACATCTACTACGCCGGTGCCAGTGTGCTGCTGACCGAAGAGGATTTC
TTCGACATGACCATGGACTACGTCAAGCGCGCCGTCGCCGACAATGTCCGCCATGCCGAGATCTTCTTCGATCCGCAGAC
CCATACGGCTCGCGGCGTGCCAATCGGCACCGTGATCGACGGCATTTCCGATGCACTGGCCCAGGCGCGCACCGAATATG
ATTTCTCGAGCAGCCTGATCCTCTGCTTCCTGCGCCATTTGTCGGAAGAAGACGCGTTCGCCACGCTGGAAGCCGCGCTG
CCGTACCGGGACCGCTTTGTCGGCGTCGGGCTGGATTCGTCGGAGAAGGGCAACCCGCCCGAAAAGTTTGCACGCGTATT
CACTCGTGCCCGCGAACTCGGCCTGCACCTGGTGGCCCATGCCGGCGAGGAAGGCCCCGCCCAGTACGTCACCGATGCGC
TGGACATCCTCAAGGTCGAACGTATCGATCACGGCGTACGTTCGATCGACGATGCCGCGCTGATCGAGCGCCTGGCGCGC
GAACGCGTGGCGCTGACCGTGTGCCCGCTTTCGAACCAGAAGCTCAAGGTGCATCCGGACCTGAGCGAGCATCCGCTCAA
GCGCATGCTCGATGCCGGCGTTGCGATCACGCTGCATTCGGACGACCCGGCCTACTTCGGCGGCTACATGAACGCCAACT
GGGAAGCCACGTTCGCAGCGCTGCCGCTCGACGCCGCCGATGCGCACAAGCTGGCGCGCAATAGTTTTGAAGCGGCCTTC
CTGCCCCCGATGCAGAAGGCCGAGTTCCTGGCGGAGGTCGACCACTTCTGGTCGGCCACGCCGACGTCCCCGCCTGCCAC
GGCCCCCGCGGCCTGA

Upstream 100 bases:

>100_bases
TCGTCGCCCAGTTGCTGCAGGTCCGCGACCAGCGCCTCGCCGCGCTGCACGCGAGCCACGGGGAGACGGTGCATCCGTAA
CCACAAGACCGAGGCCCCAC

Downstream 100 bases:

>100_bases
GCGGCACATACCAATGGCCTGGCCCTGCGCGTGCGCGCCGGCCTGGCCCGAGAGACAGACCATGACGACCACTCCTCCGA
CTCCGTCCATTACTCGCGCG

Product: adenosine deaminase

Products: NA

Alternate protein names: Adenosine aminohydrolase [H]

Number of amino acids: Translated: 351; Mature: 350

Protein sequence:

>351_residues
MTIDAALADKIRRTPKAELHVHIEGTLEPELIFRLAQRNHVNLPYPSVEALRAAYAFTDLQSFLDIYYAGASVLLTEEDF
FDMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGTVIDGISDALAQARTEYDFSSSLILCFLRHLSEEDAFATLEAAL
PYRDRFVGVGLDSSEKGNPPEKFARVFTRARELGLHLVAHAGEEGPAQYVTDALDILKVERIDHGVRSIDDAALIERLAR
ERVALTVCPLSNQKLKVHPDLSEHPLKRMLDAGVAITLHSDDPAYFGGYMNANWEATFAALPLDAADAHKLARNSFEAAF
LPPMQKAEFLAEVDHFWSATPTSPPATAPAA

Sequences:

>Translated_351_residues
MTIDAALADKIRRTPKAELHVHIEGTLEPELIFRLAQRNHVNLPYPSVEALRAAYAFTDLQSFLDIYYAGASVLLTEEDF
FDMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGTVIDGISDALAQARTEYDFSSSLILCFLRHLSEEDAFATLEAAL
PYRDRFVGVGLDSSEKGNPPEKFARVFTRARELGLHLVAHAGEEGPAQYVTDALDILKVERIDHGVRSIDDAALIERLAR
ERVALTVCPLSNQKLKVHPDLSEHPLKRMLDAGVAITLHSDDPAYFGGYMNANWEATFAALPLDAADAHKLARNSFEAAF
LPPMQKAEFLAEVDHFWSATPTSPPATAPAA
>Mature_350_residues
TIDAALADKIRRTPKAELHVHIEGTLEPELIFRLAQRNHVNLPYPSVEALRAAYAFTDLQSFLDIYYAGASVLLTEEDFF
DMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGTVIDGISDALAQARTEYDFSSSLILCFLRHLSEEDAFATLEAALP
YRDRFVGVGLDSSEKGNPPEKFARVFTRARELGLHLVAHAGEEGPAQYVTDALDILKVERIDHGVRSIDDAALIERLARE
RVALTVCPLSNQKLKVHPDLSEHPLKRMLDAGVAITLHSDDPAYFGGYMNANWEATFAALPLDAADAHKLARNSFEAAFL
PPMQKAEFLAEVDHFWSATPTSPPATAPAA

Specific function: Unknown

COG id: COG1816

COG function: function code F; Adenosine deaminase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the adenosine and AMP deaminases family [H]

Homologues:

Organism=Homo sapiens, GI47078295, Length=355, Percent_Identity=25.6338028169014, Blast_Score=119, Evalue=4e-27,
Organism=Escherichia coli, GI1787910, Length=317, Percent_Identity=28.0757097791798, Blast_Score=138, Evalue=6e-34,
Organism=Caenorhabditis elegans, GI17538512, Length=341, Percent_Identity=24.0469208211144, Blast_Score=74, Evalue=1e-13,
Organism=Caenorhabditis elegans, GI32565969, Length=341, Percent_Identity=24.0469208211144, Blast_Score=74, Evalue=1e-13,
Organism=Saccharomyces cerevisiae, GI6324188, Length=333, Percent_Identity=45.6456456456456, Blast_Score=290, Evalue=2e-79,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001365
- InterPro:   IPR006330 [H]

Pfam domain/function: PF00962 A_deaminase [H]

EC number: =3.5.4.4 [H]

Molecular weight: Translated: 38795; Mature: 38664

Theoretical pI: Translated: 4.95; Mature: 4.95

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
1.7 %Met     (Translated Protein)
2.3 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
1.4 %Met     (Mature Protein)
2.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTIDAALADKIRRTPKAELHVHIEGTLEPELIFRLAQRNHVNLPYPSVEALRAAYAFTDL
CCCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
QSFLDIYYAGASVLLTEEDFFDMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGTVID
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
GISDALAQARTEYDFSSSLILCFLRHLSEEDAFATLEAALPYRDRFVGVGLDSSEKGNPP
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCH
EKFARVFTRARELGLHLVAHAGEEGPAQYVTDALDILKVERIDHGVRSIDDAALIERLAR
HHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ERVALTVCPLSNQKLKVHPDLSEHPLKRMLDAGVAITLHSDDPAYFGGYMNANWEATFAA
HCEEEEEECCCCCCEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCEEEEE
LPLDAADAHKLARNSFEAAFLPPMQKAEFLAEVDHFWSATPTSPPATAPAA
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC
>Mature Secondary Structure 
TIDAALADKIRRTPKAELHVHIEGTLEPELIFRLAQRNHVNLPYPSVEALRAAYAFTDL
CCCHHHHHHHHCCCCCEEEEEEECCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHH
QSFLDIYYAGASVLLTEEDFFDMTMDYVKRAVADNVRHAEIFFDPQTHTARGVPIGTVID
HHHHHHHHCCCEEEEECCHHHHHHHHHHHHHHHCCCCEEEEEECCCCCCCCCCCHHHHHH
GISDALAQARTEYDFSSSLILCFLRHLSEEDAFATLEAALPYRDRFVGVGLDSSEKGNPP
HHHHHHHHHHHCCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCCCEEECCCCCCCCCCCH
EKFARVFTRARELGLHLVAHAGEEGPAQYVTDALDILKVERIDHGVRSIDDAALIERLAR
HHHHHHHHHHHHHHHHHEEECCCCCHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHH
ERVALTVCPLSNQKLKVHPDLSEHPLKRMLDAGVAITLHSDDPAYFGGYMNANWEATFAA
HCEEEEEECCCCCCEEECCCCCHHHHHHHHHCCEEEEEECCCCCCCCCCCCCCCCEEEEE
LPLDAADAHKLARNSFEAAFLPPMQKAEFLAEVDHFWSATPTSPPATAPAA
CCCCHHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA