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The map label for this gene is cutS [H]

Identifier: 73542111

GI number: 73542111

Start: 2656304

End: 2657806

Strand: Direct

Name: cutS [H]

Synonym: Reut_A2425

Alternate gene names: 73542111

Gene position: 2656304-2657806 (Clockwise)

Preceding gene: 73542109

Following gene: 73542112

Centisome position: 69.78

GC content: 67.2

Gene sequence:

>1503_bases
ATGGAGACGCAAACCATCCGCTTTTTCCACCGCGGCCAGGTCAGGGAAGTATCCGACGCCCCCGTTACCAGGACCGTGCT
GCAGTACCTGCGAGAGGACGCGCGCTGCACCGGCACCAAGGAAGGCTGCGCTGAAGGCGACTGCGGCGCCTGCACCGTCG
TGATCGGCGAGCTGCAGGACGGCGGCGATGTCGAATTCAAGGCCGTCAATGCCTGTATCCAGTTCCTGCCCACGCTCGAC
GGCAAGGCGCTGATCACCGTCGAGGATCTGCGCCAGGCCGACGGCGCCCTGCACCCAGTGCAGGAAGCCCTGGTCGAGTG
CCACGGTTCGCAATGCGGCTTCTGCACGCCCGGCTTCGTCATGTCGCTGTGGGCGCTGTACCAGCAGCACACCCCGGGCG
GCGAAGCGCCGACGCGCCAGACCATCTGCGACGCGCTGACCGGCAACCTGTGCCGCTGCACTGGCTACCGCCCGATCATC
GACGCCGGCGAGCGCATGATGGCCCTGCCTGCGCCGCACGCGAGCAAGCTCAACCCGAAGCAGATCGCCGACACGCTGCG
CAATCTCAAGCGCGGCGAGACCTTCCGCTACAGCGCGAAGGGCCAGAACTTCTTCGCGCCACGCACCGCGGCCGAGTTCG
GCGCAATCAAGGCGGCCGAGCCCGGCATCCGCATCCTTGCCGGCAGCACGGACGTGGGCCTGTGGGTCACCAAGCAGTTC
CGCGAACTCGGCAACCTGCTCTATATCGGCCAGGTCGAAGACCTTCAATCGATCGAAGAGCGCGACGGCATGATCGAGAT
CGGCGCCGGCGTGACGCTCGAGAAGGCCTACGCTGCGCTGACCGCCGCGCACCCCGAACTCGAAGAGATGTGGAAGCGCT
TCGCCTCGCTGCCGATCCGCAATGCGGGCACGCTTGGCGGCAATATCGCCAACGGCTCGCCGATCGGCGATTCGATGCCG
GCGCTGATCGCGCTCGGCGCCGAAGTGGTACTCCAGCTCGGCGCGACGCGCCGTACGCTGCCGCTCGAAGACCTGTACCT
TGCGTACCAGAAGACGGCCATGGTGGAAGGCGAGTTCGTCGCAGCGCTGCGCGTACCCGTCAAGGGCCCGCAGCACTTCA
GGACCTACAAGCTGTCCAAACGCTTTGACGAGGATATTTCGGCCGTGTGCGCGGCATTCGCGATCACAGTGGAGAACGAC
GTGATCACGCAGGCACGCGTCGCGTTCGGCGGCATGGCCGCCACACCGAAGCGCGGCGCGGCCACCGAAGCTGCATTGAT
CGGCCAGCCGTGGAACGAAGCCACCGTGCGCGCCGGCATGGCCGCGCTGTCGCAGGATTACACACCGCTGTCCGATATGC
GTTCGACCGCCTCGTACCGCACCCGCGGGGCGGCCAACCTGCTGTACCGCTTCTGGCTGGAGACGCGCGCCGATGCGCTG
CCCGCATCCGCTGTCAACGTCCGCGCGCCTGGCGCTGGCGCCACTGCAACCGTCACGGCCTGA

Upstream 100 bases:

>100_bases
CCCATGGACGGGCATCCTGATGGGGCATATCACCTGGGCCGAATATTGCATGAAACGCGCCGGTGCTATGTTTCCGCCAT
CACAGAACGAGATGAAGACC

Downstream 100 bases:

>100_bases
GGAGAGATCGGCATGAACAAGCAAACCGAACCGTTCCTGCTCGACGCCAGCGTGGCCGACGAGGCCGTGCCCCAGGTCGG
CATCTCGCGTCCGCATGAAT

Product: ferredoxin:molybdopterin dehydrogenase, FAD-binding:(2Fe-2S)-binding:CO dehydrogenase flavoprotein, C-terminal

Products: NA

Alternate protein names: CO dehydrogenase subunit S; CO-DH S [H]

Number of amino acids: Translated: 500; Mature: 500

Protein sequence:

>500_residues
METQTIRFFHRGQVREVSDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGELQDGGDVEFKAVNACIQFLPTLD
GKALITVEDLRQADGALHPVQEALVECHGSQCGFCTPGFVMSLWALYQQHTPGGEAPTRQTICDALTGNLCRCTGYRPII
DAGERMMALPAPHASKLNPKQIADTLRNLKRGETFRYSAKGQNFFAPRTAAEFGAIKAAEPGIRILAGSTDVGLWVTKQF
RELGNLLYIGQVEDLQSIEERDGMIEIGAGVTLEKAYAALTAAHPELEEMWKRFASLPIRNAGTLGGNIANGSPIGDSMP
ALIALGAEVVLQLGATRRTLPLEDLYLAYQKTAMVEGEFVAALRVPVKGPQHFRTYKLSKRFDEDISAVCAAFAITVEND
VITQARVAFGGMAATPKRGAATEAALIGQPWNEATVRAGMAALSQDYTPLSDMRSTASYRTRGAANLLYRFWLETRADAL
PASAVNVRAPGAGATATVTA

Sequences:

>Translated_500_residues
METQTIRFFHRGQVREVSDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGELQDGGDVEFKAVNACIQFLPTLD
GKALITVEDLRQADGALHPVQEALVECHGSQCGFCTPGFVMSLWALYQQHTPGGEAPTRQTICDALTGNLCRCTGYRPII
DAGERMMALPAPHASKLNPKQIADTLRNLKRGETFRYSAKGQNFFAPRTAAEFGAIKAAEPGIRILAGSTDVGLWVTKQF
RELGNLLYIGQVEDLQSIEERDGMIEIGAGVTLEKAYAALTAAHPELEEMWKRFASLPIRNAGTLGGNIANGSPIGDSMP
ALIALGAEVVLQLGATRRTLPLEDLYLAYQKTAMVEGEFVAALRVPVKGPQHFRTYKLSKRFDEDISAVCAAFAITVEND
VITQARVAFGGMAATPKRGAATEAALIGQPWNEATVRAGMAALSQDYTPLSDMRSTASYRTRGAANLLYRFWLETRADAL
PASAVNVRAPGAGATATVTA
>Mature_500_residues
METQTIRFFHRGQVREVSDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGELQDGGDVEFKAVNACIQFLPTLD
GKALITVEDLRQADGALHPVQEALVECHGSQCGFCTPGFVMSLWALYQQHTPGGEAPTRQTICDALTGNLCRCTGYRPII
DAGERMMALPAPHASKLNPKQIADTLRNLKRGETFRYSAKGQNFFAPRTAAEFGAIKAAEPGIRILAGSTDVGLWVTKQF
RELGNLLYIGQVEDLQSIEERDGMIEIGAGVTLEKAYAALTAAHPELEEMWKRFASLPIRNAGTLGGNIANGSPIGDSMP
ALIALGAEVVLQLGATRRTLPLEDLYLAYQKTAMVEGEFVAALRVPVKGPQHFRTYKLSKRFDEDISAVCAAFAITVEND
VITQARVAFGGMAATPKRGAATEAALIGQPWNEATVRAGMAALSQDYTPLSDMRSTASYRTRGAANLLYRFWLETRADAL
PASAVNVRAPGAGATATVTA

Specific function: Catalyzes the oxidation of carbon monoxide to carbon dioxide [H]

COG id: COG4630

COG function: function code F; Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 2Fe-2S ferredoxin-type domain [H]

Homologues:

Organism=Homo sapiens, GI91823271, Length=531, Percent_Identity=27.1186440677966, Blast_Score=167, Evalue=2e-41,
Organism=Homo sapiens, GI71773480, Length=465, Percent_Identity=26.6666666666667, Blast_Score=144, Evalue=3e-34,
Organism=Escherichia coli, GI1789231, Length=257, Percent_Identity=26.8482490272374, Blast_Score=83, Evalue=4e-17,
Organism=Escherichia coli, GI1786480, Length=151, Percent_Identity=35.7615894039735, Blast_Score=82, Evalue=6e-17,
Organism=Escherichia coli, GI1789232, Length=160, Percent_Identity=36.25, Blast_Score=79, Evalue=6e-16,
Organism=Caenorhabditis elegans, GI17540638, Length=537, Percent_Identity=29.7951582867784, Blast_Score=227, Evalue=1e-59,
Organism=Caenorhabditis elegans, GI17539860, Length=139, Percent_Identity=46.0431654676259, Blast_Score=122, Evalue=4e-28,
Organism=Caenorhabditis elegans, GI32566215, Length=348, Percent_Identity=29.3103448275862, Blast_Score=121, Evalue=9e-28,
Organism=Drosophila melanogaster, GI17737937, Length=548, Percent_Identity=31.2043795620438, Blast_Score=223, Evalue=3e-58,
Organism=Drosophila melanogaster, GI24647197, Length=506, Percent_Identity=29.8418972332016, Blast_Score=176, Evalue=2e-44,
Organism=Drosophila melanogaster, GI24647199, Length=493, Percent_Identity=28.8032454361055, Blast_Score=171, Evalue=1e-42,
Organism=Drosophila melanogaster, GI24647201, Length=495, Percent_Identity=28.4848484848485, Blast_Score=170, Evalue=2e-42,
Organism=Drosophila melanogaster, GI24647195, Length=329, Percent_Identity=32.5227963525836, Blast_Score=154, Evalue=2e-37,
Organism=Drosophila melanogaster, GI24647193, Length=501, Percent_Identity=26.9461077844311, Blast_Score=146, Evalue=3e-35,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR002888
- InterPro:   IPR012675
- InterPro:   IPR001041 [H]

Pfam domain/function: PF00111 Fer2; PF01799 Fer2_2 [H]

EC number: =1.2.99.2 [H]

Molecular weight: Translated: 53748; Mature: 53748

Theoretical pI: Translated: 6.19; Mature: 6.19

Prosite motif: PS00197 2FE2S_FER_1 ; PS51085 2FE2S_FER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

2.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
4.6 %Cys+Met (Translated Protein)
2.4 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
4.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
METQTIRFFHRGQVREVSDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGELQD
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCC
GGDVEFKAVNACIQFLPTLDGKALITVEDLRQADGALHPVQEALVECHGSQCGFCTPGFV
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHH
MSLWALYQQHTPGGEAPTRQTICDALTGNLCRCTGYRPIIDAGERMMALPAPHASKLNPK
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCHHHHCCCCEEECCCCCCCCCCHH
QIADTLRNLKRGETFRYSAKGQNFFAPRTAAEFGAIKAAEPGIRILAGSTDVGLWVTKQF
HHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHH
RELGNLLYIGQVEDLQSIEERDGMIEIGAGVTLEKAYAALTAAHPELEEMWKRFASLPIR
HHHCCEEEEECHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCC
NAGTLGGNIANGSPIGDSMPALIALGAEVVLQLGATRRTLPLEDLYLAYQKTAMVEGEFV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEE
AALRVPVKGPQHFRTYKLSKRFDEDISAVCAAFAITVENDVITQARVAFGGMAATPKRGA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCCCCCC
ATEAALIGQPWNEATVRAGMAALSQDYTPLSDMRSTASYRTRGAANLLYRFWLETRADAL
CCCHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PASAVNVRAPGAGATATVTA
CCCCEEEECCCCCCEEEECC
>Mature Secondary Structure
METQTIRFFHRGQVREVSDAPVTRTVLQYLREDARCTGTKEGCAEGDCGACTVVIGELQD
CCCCEEEEEECCCCCCCCCCCHHHHHHHHHHHHHCCCCCCCCCCCCCCCEEEEEEEECCC
GGDVEFKAVNACIQFLPTLDGKALITVEDLRQADGALHPVQEALVECHGSQCGFCTPGFV
CCCCHHHHHHHHHHHHCCCCCCEEEEHHHHHHHCCCCCHHHHHHHHHCCCCCCCCCHHHH
MSLWALYQQHTPGGEAPTRQTICDALTGNLCRCTGYRPIIDAGERMMALPAPHASKLNPK
HHHHHHHHHCCCCCCCCHHHHHHHHHCCCCEEECCCCHHHHCCCCEEECCCCCCCCCCHH
QIADTLRNLKRGETFRYSAKGQNFFAPRTAAEFGAIKAAEPGIRILAGSTDVGLWVTKQF
HHHHHHHHHHCCCCEEEECCCCCCCCCCHHHHHCCCCCCCCCEEEEECCCCCCHHHHHHH
RELGNLLYIGQVEDLQSIEERDGMIEIGAGVTLEKAYAALTAAHPELEEMWKRFASLPIR
HHHCCEEEEECHHHHHHHHHCCCEEEECCCCCHHHHHHHHHHCCCCHHHHHHHHHCCCCC
NAGTLGGNIANGSPIGDSMPALIALGAEVVLQLGATRRTLPLEDLYLAYQKTAMVEGEFV
CCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHCCCCCCCCHHHHHHHHHHHHHCCCCEE
AALRVPVKGPQHFRTYKLSKRFDEDISAVCAAFAITVENDVITQARVAFGGMAATPKRGA
EEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHEEECCCHHHHHHHHHCCCCCCCCCCC
ATEAALIGQPWNEATVRAGMAALSQDYTPLSDMRSTASYRTRGAANLLYRFWLETRADAL
CCCHHHCCCCCCHHHHHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
PASAVNVRAPGAGATATVTA
CCCCEEEECCCCCCEEEECC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 10482497; 2818128; 10966817; 11076018 [H]