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The map label for this gene is fabD [H]

Identifier: 73541951

GI number: 73541951

Start: 2496308

End: 2497237

Strand: Reverse

Name: fabD [H]

Synonym: Reut_A2264

Alternate gene names: 73541951

Gene position: 2497237-2496308 (Counterclockwise)

Preceding gene: 73541952

Following gene: 73541950

Centisome position: 65.6

GC content: 67.96

Gene sequence:

>930_bases
ATGAAATTTGCATTCGTATTTCCTGGCCAGGGCTCGCAGTCGGTCGGCATGCTCAATGCGTTCGCCGACAACGCCGTGGT
GCGCGCTACCCTGGAGGAAGCTTCGACGGCACTCGGCCAGGACATCGGCCGCCTGATCGCCGAAGGCCCGGCTGAAGAAC
TGAACCTGACCACCAACACGCAGCCGGTCATGCTGACCGCCGCCGTGGCGGTCTACCGCGCATGGCTCGACGCCGGCGGT
CCGGCGCCCGCAATGGTGGCTGGCCACAGCCTGGGCGAATACTCGGCACTGGTCGCGGCCGGCGTGATTCCGTTCGCCGA
AGCCGTACCGCTGGTGCGTTTCCGTGCACAAGCCATGCAGGAGGCGGTACCGGTGGGCCAGGGCGGCATGGCCGCCATCC
TGGGCCTGTCCGACGATGACGTGCGTGCTGCCTGCGCCGAAGCGTCGGCTGCTGGCGTGGTCGAGGCCGTCAATTTCAAC
GCACCGTCGCAGGTCGTGATCGCTGGTAGCAAGGCCGGCGTCGAGAAGGCCTGCGAAGTCGCGAAGGCCAAGGGCGCCAA
GCGTGCGCTGCCGCTGCCGGTGTCGGCGCCGTTCCACTCGTCGCTGCTCAAGCCGGCGTCGGACCGCCTGCGCGAGCGCA
TGGCCGGCCTGACGTTCTCGGCACCGACCATTCCGCTGGTCAACAACGTGGACGTCGCCATCGTCAACGATCCGGAAGCG
ATCAAGGACGCGCTCGTTCGCCAGGCCGCCGCGCCGGTGCGCTGGGTGGAGTGCGTGCAGAAGATGGCCGCCGAAGGCGT
CACGCACGTGATCGAATGCGGCCCGGGCAAGGTCCTGGCCGGCATGACCAAGCGTATCGACGGCAGCCTGACCGGCGGCG
CGGTGTTCGATCCGGCCTCGCTGCAGGAAACCCTGGCGCTGCTGAAGTAA

Upstream 100 bases:

>100_bases
TCACCTGGGGCGCTGCGCTGCTGCGCATGTAACGACAGCCGGCGCGGCGGGCGAGACCGGACGCGCGGCTACCGGTATTC
AAATCTAGGATTGCACTCCG

Downstream 100 bases:

>100_bases
GCGAACGCAAGAAAAGGATAATTAGCATGACCAAACTTCTCGAGAACCAGGTCGCACTGGTCACCGGCGCTTCGCGTGGC
ATTGGCCGCGCCATCGCGCT

Product: [Acyl-carrier-protein] S-malonyltransferase

Products: NA

Alternate protein names: MCT [H]

Number of amino acids: Translated: 309; Mature: 309

Protein sequence:

>309_residues
MKFAFVFPGQGSQSVGMLNAFADNAVVRATLEEASTALGQDIGRLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWLDAGG
PAPAMVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQEAVPVGQGGMAAILGLSDDDVRAACAEASAAGVVEAVNFN
APSQVVIAGSKAGVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLTFSAPTIPLVNNVDVAIVNDPEA
IKDALVRQAAAPVRWVECVQKMAAEGVTHVIECGPGKVLAGMTKRIDGSLTGGAVFDPASLQETLALLK

Sequences:

>Translated_309_residues
MKFAFVFPGQGSQSVGMLNAFADNAVVRATLEEASTALGQDIGRLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWLDAGG
PAPAMVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQEAVPVGQGGMAAILGLSDDDVRAACAEASAAGVVEAVNFN
APSQVVIAGSKAGVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLTFSAPTIPLVNNVDVAIVNDPEA
IKDALVRQAAAPVRWVECVQKMAAEGVTHVIECGPGKVLAGMTKRIDGSLTGGAVFDPASLQETLALLK
>Mature_309_residues
MKFAFVFPGQGSQSVGMLNAFADNAVVRATLEEASTALGQDIGRLIAEGPAEELNLTTNTQPVMLTAAVAVYRAWLDAGG
PAPAMVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQEAVPVGQGGMAAILGLSDDDVRAACAEASAAGVVEAVNFN
APSQVVIAGSKAGVEKACEVAKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLTFSAPTIPLVNNVDVAIVNDPEA
IKDALVRQAAAPVRWVECVQKMAAEGVTHVIECGPGKVLAGMTKRIDGSLTGGAVFDPASLQETLALLK

Specific function: Fatty acid biosynthesis. [C]

COG id: COG0331

COG function: function code I; (acyl-carrier-protein) S-malonyltransferase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fabD family [H]

Homologues:

Organism=Homo sapiens, GI51243059, Length=301, Percent_Identity=30.2325581395349, Blast_Score=135, Evalue=7e-32,
Organism=Escherichia coli, GI1787334, Length=307, Percent_Identity=58.6319218241042, Blast_Score=332, Evalue=2e-92,
Organism=Caenorhabditis elegans, GI71984332, Length=291, Percent_Identity=29.2096219931272, Blast_Score=118, Evalue=4e-27,
Organism=Caenorhabditis elegans, GI17550940, Length=295, Percent_Identity=31.1864406779661, Blast_Score=115, Evalue=4e-26,
Organism=Caenorhabditis elegans, GI212642053, Length=292, Percent_Identity=26.7123287671233, Blast_Score=67, Evalue=2e-11,
Organism=Drosophila melanogaster, GI24665753, Length=298, Percent_Identity=30.8724832214765, Blast_Score=125, Evalue=4e-29,

Paralogues:

None

Copy number: 500 Molecules/Cell In: Growth Phase, Minimal Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR001227
- InterPro:   IPR014043
- InterPro:   IPR016035
- InterPro:   IPR004410
- InterPro:   IPR016036 [H]

Pfam domain/function: PF00698 Acyl_transf_1 [H]

EC number: =2.3.1.39 [H]

Molecular weight: Translated: 31675; Mature: 31675

Theoretical pI: Translated: 5.15; Mature: 5.15

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.9 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.9 %Met     (Mature Protein)
4.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADNAVVRATLEEASTALGQDIGRLIAEGPAEELNLTTNT
CEEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAVAVYRAWLDAGGPAPAMVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPVGQGGMAAILGLSDDDVRAACAEASAAGVVEAVNFNAPSQVVIAGSKAGVEKACEV
HHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLTFSAPTIPLVNNVDVAIVNDPEA
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCEECCCCCCEECCCCEEEECCHHH
IKDALVRQAAAPVRWVECVQKMAAEGVTHVIECGPGKVLAGMTKRIDGSLTGGAVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCCEECHHH
LQETLALLK
HHHHHHHCC
>Mature Secondary Structure
MKFAFVFPGQGSQSVGMLNAFADNAVVRATLEEASTALGQDIGRLIAEGPAEELNLTTNT
CEEEEEECCCCCCCCHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCC
QPVMLTAAVAVYRAWLDAGGPAPAMVAGHSLGEYSALVAAGVIPFAEAVPLVRFRAQAMQ
CCHHHHHHHHHHHHHHHCCCCCCHHHHCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
EAVPVGQGGMAAILGLSDDDVRAACAEASAAGVVEAVNFNAPSQVVIAGSKAGVEKACEV
HHCCCCCCCCEEEEECCCCHHHHHHHHHHHCCCEEEECCCCCCEEEEECCCCCHHHHHHH
AKAKGAKRALPLPVSAPFHSSLLKPASDRLRERMAGLTFSAPTIPLVNNVDVAIVNDPEA
HHHCCCCCCCCCCCCCCHHHHHHCCHHHHHHHHHHCCEECCCCCCEECCCCEEEECCHHH
IKDALVRQAAAPVRWVECVQKMAAEGVTHVIECGPGKVLAGMTKRIDGSLTGGAVFDPAS
HHHHHHHHHCCCHHHHHHHHHHHHCCCCEEEECCCCHHHHHHHHHCCCCCCCCCEECHHH
LQETLALLK
HHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]