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The map label for this gene is glpR [H]

Identifier: 73541897

GI number: 73541897

Start: 2443364

End: 2444143

Strand: Direct

Name: glpR [H]

Synonym: Reut_A2210

Alternate gene names: 73541897

Gene position: 2443364-2444143 (Clockwise)

Preceding gene: 73541890

Following gene: 73541900

Centisome position: 64.19

GC content: 63.97

Gene sequence:

>780_bases
ATGCCTCGCATGACCCTGAATCCCCGCCAGACCGCCCTTCTCGAAGAAGTCCGCACCCAGGGCTTCGCGTCGATCGACGC
GCTTGCGCGAAAATTCGGCGTGACATTGCAGACCGTTCGGCGCGACGTGAATCTGCTGGCCGAAGGCGGCATGCTCGCGC
GATTCCACGGCGGGGTGCGGGTCGAGGGCTCGACGACAGAGAACATCGCTTACCGGCAGCGGCAGGTGCTAAATGCCCAA
GGCAAGGTGCGCATTGCGCGCGCGGTGGCCAAGGTGGTACCCGAAGGCTGCTCGCTGATCCTGAACATCGGCACCACGGT
GGAAGAGATTGCGCGTGCGCTGATGCATCACCGCGGCTTGCGCGTGATCACGAACAACTTGAACGTGGCCAATATCCTGG
CGGACAACCCCGACTGCGAAGTCATCGTCGCTGGCGGCGTATTGCGCTCGCGCGACCGCGGCATCGTCGGCGAAGCGACG
GTGGAGTTCATCCGCCAGTTCAAGGTCGATATCGGGCTGATCGGCATCTCGGGCATCGAGGCCGACGGCACGCTGCGTGA
CTACGATTTCCGCGAGGTCAAGGTGGCACGCACGATCATGGAGCACGCGCGCGAGGTGTGGCTGGCCGCGGATGCCAGCA
AGTTCCATCGCCAGGCAATGGTGGAACTGGCGCACCTGTCGCAGATCGATAGGCTGTTCACCGATGAGCCGCTGGTGGCC
CCGTTCGGGCAGATCGTGGCGGACAGCGGAGTGAAATGTGTGGTGGCGGACCAGGACTGA

Upstream 100 bases:

>100_bases
TGCGGGCGCCCAATGTGTGGCTTATGCTCGTTTTAGTAAATGAACGAACATAAAACAATAGTGCACCGCATCATTTGTTT
TCGTTTGTGTTTGAACTAGA

Downstream 100 bases:

>100_bases
CCCTGCCGCCGCGGCGGCGCACGCCAGTATCCGCATACCGGCCGGCGCGATGCGCGCCGGCGGCGAATTGCAGCAATTAC
TTGAAGACGACGGTCTTGTG

Product: DeoR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 259; Mature: 258

Protein sequence:

>259_residues
MPRMTLNPRQTALLEEVRTQGFASIDALARKFGVTLQTVRRDVNLLAEGGMLARFHGGVRVEGSTTENIAYRQRQVLNAQ
GKVRIARAVAKVVPEGCSLILNIGTTVEEIARALMHHRGLRVITNNLNVANILADNPDCEVIVAGGVLRSRDRGIVGEAT
VEFIRQFKVDIGLIGISGIEADGTLRDYDFREVKVARTIMEHAREVWLAADASKFHRQAMVELAHLSQIDRLFTDEPLVA
PFGQIVADSGVKCVVADQD

Sequences:

>Translated_259_residues
MPRMTLNPRQTALLEEVRTQGFASIDALARKFGVTLQTVRRDVNLLAEGGMLARFHGGVRVEGSTTENIAYRQRQVLNAQ
GKVRIARAVAKVVPEGCSLILNIGTTVEEIARALMHHRGLRVITNNLNVANILADNPDCEVIVAGGVLRSRDRGIVGEAT
VEFIRQFKVDIGLIGISGIEADGTLRDYDFREVKVARTIMEHAREVWLAADASKFHRQAMVELAHLSQIDRLFTDEPLVA
PFGQIVADSGVKCVVADQD
>Mature_258_residues
PRMTLNPRQTALLEEVRTQGFASIDALARKFGVTLQTVRRDVNLLAEGGMLARFHGGVRVEGSTTENIAYRQRQVLNAQG
KVRIARAVAKVVPEGCSLILNIGTTVEEIARALMHHRGLRVITNNLNVANILADNPDCEVIVAGGVLRSRDRGIVGEATV
EFIRQFKVDIGLIGISGIEADGTLRDYDFREVKVARTIMEHAREVWLAADASKFHRQAMVELAHLSQIDRLFTDEPLVAP
FGQIVADSGVKCVVADQD

Specific function: Repressor of the glycerol-3-phosphate regulon [H]

COG id: COG1349

COG function: function code KG; Transcriptional regulators of sugar metabolism

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH deoR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI1789829, Length=249, Percent_Identity=44.1767068273092, Blast_Score=228, Evalue=3e-61,
Organism=Escherichia coli, GI87082344, Length=259, Percent_Identity=41.3127413127413, Blast_Score=214, Evalue=6e-57,
Organism=Escherichia coli, GI1789519, Length=251, Percent_Identity=26.2948207171315, Blast_Score=114, Evalue=8e-27,
Organism=Escherichia coli, GI1789059, Length=249, Percent_Identity=29.3172690763052, Blast_Score=114, Evalue=9e-27,
Organism=Escherichia coli, GI226510968, Length=230, Percent_Identity=30.8695652173913, Blast_Score=111, Evalue=5e-26,
Organism=Escherichia coli, GI1788069, Length=252, Percent_Identity=28.968253968254, Blast_Score=107, Evalue=5e-25,
Organism=Escherichia coli, GI1787540, Length=237, Percent_Identity=28.6919831223629, Blast_Score=92, Evalue=4e-20,
Organism=Escherichia coli, GI1789170, Length=234, Percent_Identity=23.9316239316239, Blast_Score=79, Evalue=4e-16,
Organism=Escherichia coli, GI1790753, Length=224, Percent_Identity=28.125, Blast_Score=77, Evalue=1e-15,
Organism=Escherichia coli, GI1790635, Length=238, Percent_Identity=27.7310924369748, Blast_Score=74, Evalue=1e-14,

Paralogues:

None

Copy number: 900 Molecules/Cell In: Growth Phase, Glucose-minimal MOPS Media. [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR014036
- InterPro:   IPR001034
- InterPro:   IPR018356
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00455 DeoR; PF08220 HTH_DeoR [H]

EC number: NA

Molecular weight: Translated: 28446; Mature: 28315

Theoretical pI: Translated: 7.60; Mature: 7.60

Prosite motif: PS00894 HTH_DEOR_1 ; PS51000 HTH_DEOR_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.2 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
3.5 %Cys+Met (Translated Protein)
1.2 %Cys     (Mature Protein)
1.9 %Met     (Mature Protein)
3.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MPRMTLNPRQTALLEEVRTQGFASIDALARKFGVTLQTVRRDVNLLAEGGMLARFHGGVR
CCCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCEE
VEGSTTENIAYRQRQVLNAQGKVRIARAVAKVVPEGCSLILNIGTTVEEIARALMHHRGL
EECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCC
RVITNNLNVANILADNPDCEVIVAGGVLRSRDRGIVGEATVEFIRQFKVDIGLIGISGIE
EEEECCCCEEEEEECCCCCEEEEECCEEECCCCCCCHHHHHHHHHHHHHHEEEEEECCCC
ADGTLRDYDFREVKVARTIMEHAREVWLAADASKFHRQAMVELAHLSQIDRLFTDEPLVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
PFGQIVADSGVKCVVADQD
HHHHHHHCCCCEEEEECCC
>Mature Secondary Structure 
PRMTLNPRQTALLEEVRTQGFASIDALARKFGVTLQTVRRDVNLLAEGGMLARFHGGVR
CCCCCCHHHHHHHHHHHHCCCHHHHHHHHHHCCHHHHHHHHHHHHHCCCEEEEECCCEE
VEGSTTENIAYRQRQVLNAQGKVRIARAVAKVVPEGCSLILNIGTTVEEIARALMHHRGL
EECCCCHHHHHHHHHHHCCCCCHHHHHHHHHHCCCCCEEEEECCCCHHHHHHHHHHHCCC
RVITNNLNVANILADNPDCEVIVAGGVLRSRDRGIVGEATVEFIRQFKVDIGLIGISGIE
EEEECCCCEEEEEECCCCCEEEEECCEEECCCCCCCHHHHHHHHHHHHHHEEEEEECCCC
ADGTLRDYDFREVKVARTIMEHAREVWLAADASKFHRQAMVELAHLSQIDRLFTDEPLVA
CCCCCCCCCHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHCCCCCHH
PFGQIVADSGVKCVVADQD
HHHHHHHCCCCEEEEECCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8752340; 10984043 [H]