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The map label for this gene is rpiA [H]

Identifier: 73541756

GI number: 73541756

Start: 2273148

End: 2273834

Strand: Reverse

Name: rpiA [H]

Synonym: Reut_A2068

Alternate gene names: 73541756

Gene position: 2273834-2273148 (Counterclockwise)

Preceding gene: 73541758

Following gene: 73541753

Centisome position: 59.74

GC content: 64.77

Gene sequence:

>687_bases
ATGACTCAGGATGAACTCAAGGCGCTGGTGGCGCAAGCCGCGGCCGACTACGTGAAGCAGGAAGTCCCGGAAGGCGCCGT
GCTCGGCGTTGGCACCGGTTCCACGGCCAATCTTTTCATTGACGCCGTGGCGGCGTTCAAGGATCGCTTCGCGGGTGCGG
TATCGAGCTCCGAGGCGTCCACGCGCCGGTTGCAACAGCATGGCTTCAAGGTGCTCGACCTCAATGAAGTCGACGATATC
CCCGTCTATGTCGACGGCGCCGACGAGATCGACGCAAGTGGCGCGATGATCAAGGGCGGTGGCGGCGCGCTGACCCGCGA
GAAGATCGTGGCCTCGGTCGCCGGCCGTTTCGTCTGCATCGCGGACGGCAGTAAGCTCGTCGAAACGATGGGCGCCTTCC
CGCTGCCCGTCGAAGTGATTCCGATGGCACGCGCGGCGGTCGCGCGCCAAGTCGCCGCGCTTGGCGGCCAGCCCCGCCTG
CGCATGAACAAGGACGGCGGCATTTACAAGACCGACAATGGCAATGTGATTCTGGACGTAAGCGGCCTGAAAATCACCGA
TCCGCGCGGGTTGGAACAGTCGATCAACCAGATTCCCGGCGTCGTGACCGTGGGCCTGTTCGCGCTGCGCGGTGCGAACG
TGCTGCTGCTCGGCACGGGCGAGGGCGTGCAGCGCACCGATTACTGA

Upstream 100 bases:

>100_bases
GACTCGCGGCGCCGTTGAGGCATTGTACCGTCGCGGGCAGCCTTGCCATCGCAATCCGCTACACTACGCGTTTTTCCCCG
AAAGCCATCTGGCTGTTGTC

Downstream 100 bases:

>100_bases
TCGGCCAGTGGCTGCAAGCCACAATGAAAATGGGGTGCCGGCGGCACCCCATTTTCATTTCAATCGTGCAGGAAGATCAG
GCCTGCGGAGGCACGTAGCC

Product: ribose-5-phosphate isomerase A

Products: NA

Alternate protein names: Phosphoriboisomerase A; PRI [H]

Number of amino acids: Translated: 228; Mature: 227

Protein sequence:

>228_residues
MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKDRFAGAVSSSEASTRRLQQHGFKVLDLNEVDDI
PVYVDGADEIDASGAMIKGGGGALTREKIVASVAGRFVCIADGSKLVETMGAFPLPVEVIPMARAAVARQVAALGGQPRL
RMNKDGGIYKTDNGNVILDVSGLKITDPRGLEQSINQIPGVVTVGLFALRGANVLLLGTGEGVQRTDY

Sequences:

>Translated_228_residues
MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKDRFAGAVSSSEASTRRLQQHGFKVLDLNEVDDI
PVYVDGADEIDASGAMIKGGGGALTREKIVASVAGRFVCIADGSKLVETMGAFPLPVEVIPMARAAVARQVAALGGQPRL
RMNKDGGIYKTDNGNVILDVSGLKITDPRGLEQSINQIPGVVTVGLFALRGANVLLLGTGEGVQRTDY
>Mature_227_residues
TQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKDRFAGAVSSSEASTRRLQQHGFKVLDLNEVDDIP
VYVDGADEIDASGAMIKGGGGALTREKIVASVAGRFVCIADGSKLVETMGAFPLPVEVIPMARAAVARQVAALGGQPRLR
MNKDGGIYKTDNGNVILDVSGLKITDPRGLEQSINQIPGVVTVGLFALRGANVLLLGTGEGVQRTDY

Specific function: Nonoxidative branch of the pentose phosphate pathway. [C]

COG id: COG0120

COG function: function code G; Ribose 5-phosphate isomerase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the ribose 5-phosphate isomerase family [H]

Homologues:

Organism=Homo sapiens, GI94536842, Length=216, Percent_Identity=39.8148148148148, Blast_Score=120, Evalue=1e-27,
Organism=Escherichia coli, GI1789280, Length=224, Percent_Identity=61.1607142857143, Blast_Score=258, Evalue=2e-70,
Organism=Caenorhabditis elegans, GI17551758, Length=202, Percent_Identity=36.1386138613861, Blast_Score=100, Evalue=5e-22,
Organism=Saccharomyces cerevisiae, GI6324669, Length=212, Percent_Identity=27.8301886792453, Blast_Score=74, Evalue=2e-14,
Organism=Drosophila melanogaster, GI281364072, Length=206, Percent_Identity=36.4077669902913, Blast_Score=101, Evalue=5e-22,

Paralogues:

None

Copy number: 740 Molecules/Cell In: Growth-Phase, Minimal-Media (Based on E. coli). [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004788
- InterPro:   IPR020672 [H]

Pfam domain/function: PF06026 Rib_5-P_isom_A [H]

EC number: =5.3.1.6 [H]

Molecular weight: Translated: 23712; Mature: 23581

Theoretical pI: Translated: 4.75; Mature: 4.75

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.4 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.6 %Cys+Met (Translated Protein)
0.4 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.2 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MTQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKDRFAGAVSSSEAS
CCHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
TRRLQQHGFKVLDLNEVDDIPVYVDGADEIDASGAMIKGGGGALTREKIVASVAGRFVCI
HHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCEEEE
ADGSKLVETMGAFPLPVEVIPMARAAVARQVAALGGQPRLRMNKDGGIYKTDNGNVILDV
ECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCEEEEE
SGLKITDPRGLEQSINQIPGVVTVGLFALRGANVLLLGTGEGVQRTDY
CCEEEECCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCC
>Mature Secondary Structure 
TQDELKALVAQAAADYVKQEVPEGAVLGVGTGSTANLFIDAVAAFKDRFAGAVSSSEAS
CHHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCCHHHHHHHHHHHHHHHHCCCCCCHHH
TRRLQQHGFKVLDLNEVDDIPVYVDGADEIDASGAMIKGGGGALTREKIVASVAGRFVCI
HHHHHHCCCEEEECCCCCCCCEEECCCCCCCCCCCEEECCCCCHHHHHHHHHHHCCEEEE
ADGSKLVETMGAFPLPVEVIPMARAAVARQVAALGGQPRLRMNKDGGIYKTDNGNVILDV
ECCHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCCCCCEEECCCCCEEEECCCCEEEEE
SGLKITDPRGLEQSINQIPGVVTVGLFALRGANVLLLGTGEGVQRTDY
CCEEEECCCCHHHHHHHCCCHHHHHHHHHCCCCEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: NA