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The map label for this gene is yheS [H]

Identifier: 73541619

GI number: 73541619

Start: 2117502

End: 2119433

Strand: Direct

Name: yheS [H]

Synonym: Reut_A1930

Alternate gene names: 73541619

Gene position: 2117502-2119433 (Clockwise)

Preceding gene: 73541608

Following gene: 73541624

Centisome position: 55.63

GC content: 66.56

Gene sequence:

>1932_bases
GTGATCCGAATCGACCAGCTTGTCCTCCAGCGCGGCACCAAGGTGCTGTTCGACCACACCAGCGTGACGCTCAACCCGGG
CGAGCGCGTGGGCCTCGTCGGCGCCAACGGCAGCGGCAAGTCCACGCTGTTCGCCATGCTGCGCGGCGAACTGCATGCGG
ATGGCGGCGACGTGACGGTGCCTGCCCAATGGCGCATCGCGCATGTGGCGCAAGAGACGCCGGCGGTGGCGCGTAGCGCG
GTCGAATACGTGATCGACGGCGATACACGCCTGCGAGAGATCGAAGCCGCCATTGCCGAGGCGCAGGCAGTCGGCGACGG
CAGCGCGGAAGGCGAAGCGCACGCGGCCTTTGCCGACGCCGACGGCTACACCGCCCCGGCGCGCGCCGAGGCGCTGCTGT
TGGGCCTCGGTTTCACGCTGCCGCAGGTGTCGCAGCCGGTATCGTCGTTCTCGGGCGGATGGCGCATGCGCCTGAACCTG
GCCCAGGCCCTGATGTGCCCGTCGGACCTGCTGCTGCTCGATGAACCGACCAATCACCTGGACCTCGACGCCATCGTCTG
GCTCGAAGACTGGCTCGCGCGCTACCCCGGCACGCTGGTCATGATTTCGCACGACCGTGAATTCCTGGACGCGATCTGCA
ACGTCACGGTCCATATCGAGAATCAGCAGTTGCGCCGCTACGGCGGCAACTACACGCTGTTCGAGACGCTGCGCCTGCAG
CAGATGGCGCAGCAGCAGGCGGCCTATACCCGCCAGCAAAAGGAAATCGCGCACCTGGAATCGTTCATCACGCGCTTCAA
GGCCAAGGCGACCAAGGCGCGCCAGGCGCAAAGCCGCGTCAAGGCACTCGAGAAGATGGAACGGCTGGCGCCAGTGCACG
TCGCCGCGGGCTTCGCCTTCGAATTCCGCGAGCCCGATGCGGCGCCGAACCCGATGATGGTGCTGGACGGCGTCGACTGC
GGCTATGCCGAGGCCGATCCGCCGGCGACCATCCTGCACAAGCTGGCGCTGTCGATCCAGAACGGCCAGCGCATCGGCCT
GCTCGGCGCCAACGGGCAGGGCAAGTCGACGCTGGTCAAGACGCTGGCCGGCACGCAGGATCCGCTGACCGGCACGCTGC
GCCTGGGCAAGGGCCTGCAGATCGGCTACTTCGCCCAGCACCAGCTGGAAACGCTGCGTGACCACGAATCTCCGCTGCAG
CACCTGGCGCGACTGGCGCCGGACACCCGCGAGCAGGAACTGCGCGATTTCCTCGGCAGCTTCAATTTCCGCGGCGATAT
GGCCACCGCGCCGATCGAGCCGTTCTCGGGGGGCGAAAAAGCCCGCCTGGCGCTGTCGCTGATCGTCTGGCAGAAGCCCA
ACCTGCTGCTGCTCGACGAACCGACCAACCACCTGGACCTCGACACGCGCGAGGCGCTGACCATGGCGCTGGCGCAGTTC
GAAGGCACGCTGATCCTGGTTTCGCACGACCGTCACCTGCTGCGCGCTACGGCCGACCAGTTCATGCTGGTCGCCGATGG
CACCATCAAACCGTTCGACGGCGACCTCGACGACTATCGCGACTGGCTGCTGCAGCAGGCCGCGGCCAAGCGCAACGCCG
CCGTGGCCGCGCACCAGGGGGAAACCGGCGGCAACGCCGCAGCGGTCAACCGCAAGGACCAGCGCCGCGCCGAAGCGGAC
GAGCGCCAGCGGCTGGCGCAACTGCGCAAGCCGCTGACCAAGGAACTGGAAAAGGTGGAAAAGCGCATGACGGTGCTGCA
GACCGCCAAGGCCGAGATCGACCAGTTCATGGCCGATGAGACCAGCTATGCCGAGGCCAACAAGTCAAAGCTGATGGAGA
TGCTCAAGCGCCAGGGCGAAGTCAACGGCGAACTGGAAACGCTCGAAGAGAAATGGCTGGAGCTGCAGGAGCAGATCGAA
CAGATCGAGTGA

Upstream 100 bases:

>100_bases
CTACAATGCCGCCCAGCGCCTCATCTCGGGCTGCTGTCCGCGCTTTCTCGCGCTTTTCCGCTGTTTTTTATCCCCGCTTA
CCGACGCTCCTGCCTTACCC

Downstream 100 bases:

>100_bases
AGGGGTTCGAGTCCGCTACCTCGTATCCACCCATCGAATGTCGTGGCTGCGAACAAAAACCGGCGCTCAAGGCGCCGGTT
TTTCTATCCGATCAACGGAA

Product: ABC transporter related

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 643; Mature: 643

Protein sequence:

>643_residues
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFAMLRGELHADGGDVTVPAQWRIAHVAQETPAVARSA
VEYVIDGDTRLREIEAAIAEAQAVGDGSAEGEAHAAFADADGYTAPARAEALLLGLGFTLPQVSQPVSSFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLRRYGGNYTLFETLRLQ
QMAQQQAAYTRQQKEIAHLESFITRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAFEFREPDAAPNPMMVLDGVDC
GYAEADPPATILHKLALSIQNGQRIGLLGANGQGKSTLVKTLAGTQDPLTGTLRLGKGLQIGYFAQHQLETLRDHESPLQ
HLARLAPDTREQELRDFLGSFNFRGDMATAPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
EGTLILVSHDRHLLRATADQFMLVADGTIKPFDGDLDDYRDWLLQQAAAKRNAAVAAHQGETGGNAAAVNRKDQRRAEAD
ERQRLAQLRKPLTKELEKVEKRMTVLQTAKAEIDQFMADETSYAEANKSKLMEMLKRQGEVNGELETLEEKWLELQEQIE
QIE

Sequences:

>Translated_643_residues
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFAMLRGELHADGGDVTVPAQWRIAHVAQETPAVARSA
VEYVIDGDTRLREIEAAIAEAQAVGDGSAEGEAHAAFADADGYTAPARAEALLLGLGFTLPQVSQPVSSFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLRRYGGNYTLFETLRLQ
QMAQQQAAYTRQQKEIAHLESFITRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAFEFREPDAAPNPMMVLDGVDC
GYAEADPPATILHKLALSIQNGQRIGLLGANGQGKSTLVKTLAGTQDPLTGTLRLGKGLQIGYFAQHQLETLRDHESPLQ
HLARLAPDTREQELRDFLGSFNFRGDMATAPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
EGTLILVSHDRHLLRATADQFMLVADGTIKPFDGDLDDYRDWLLQQAAAKRNAAVAAHQGETGGNAAAVNRKDQRRAEAD
ERQRLAQLRKPLTKELEKVEKRMTVLQTAKAEIDQFMADETSYAEANKSKLMEMLKRQGEVNGELETLEEKWLELQEQIE
QIE
>Mature_643_residues
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFAMLRGELHADGGDVTVPAQWRIAHVAQETPAVARSA
VEYVIDGDTRLREIEAAIAEAQAVGDGSAEGEAHAAFADADGYTAPARAEALLLGLGFTLPQVSQPVSSFSGGWRMRLNL
AQALMCPSDLLLLDEPTNHLDLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLRRYGGNYTLFETLRLQ
QMAQQQAAYTRQQKEIAHLESFITRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAFEFREPDAAPNPMMVLDGVDC
GYAEADPPATILHKLALSIQNGQRIGLLGANGQGKSTLVKTLAGTQDPLTGTLRLGKGLQIGYFAQHQLETLRDHESPLQ
HLARLAPDTREQELRDFLGSFNFRGDMATAPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
EGTLILVSHDRHLLRATADQFMLVADGTIKPFDGDLDDYRDWLLQQAAAKRNAAVAAHQGETGGNAAAVNRKDQRRAEAD
ERQRLAQLRKPLTKELEKVEKRMTVLQTAKAEIDQFMADETSYAEANKSKLMEMLKRQGEVNGELETLEEKWLELQEQIE
QIE

Specific function: Unknown

COG id: COG0488

COG function: function code R; ATPase components of ABC transporters with duplicated ATPase domains

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 2 ABC transporter domains [H]

Homologues:

Organism=Homo sapiens, GI148612853, Length=536, Percent_Identity=39.9253731343284, Blast_Score=372, Evalue=1e-103,
Organism=Homo sapiens, GI10947137, Length=532, Percent_Identity=36.2781954887218, Blast_Score=324, Evalue=2e-88,
Organism=Homo sapiens, GI27881506, Length=532, Percent_Identity=36.2781954887218, Blast_Score=323, Evalue=2e-88,
Organism=Homo sapiens, GI69354671, Length=545, Percent_Identity=33.0275229357798, Blast_Score=260, Evalue=3e-69,
Organism=Homo sapiens, GI10947135, Length=545, Percent_Identity=33.0275229357798, Blast_Score=260, Evalue=3e-69,
Organism=Escherichia coli, GI1789751, Length=642, Percent_Identity=53.1152647975078, Blast_Score=685, Evalue=0.0,
Organism=Escherichia coli, GI1787041, Length=528, Percent_Identity=35.4166666666667, Blast_Score=327, Evalue=2e-90,
Organism=Escherichia coli, GI2367384, Length=525, Percent_Identity=29.1428571428571, Blast_Score=212, Evalue=5e-56,
Organism=Escherichia coli, GI1787182, Length=601, Percent_Identity=29.6173044925125, Blast_Score=211, Evalue=1e-55,
Organism=Escherichia coli, GI1788165, Length=180, Percent_Identity=33.3333333333333, Blast_Score=89, Evalue=1e-18,
Organism=Escherichia coli, GI1787164, Length=217, Percent_Identity=31.7972350230415, Blast_Score=69, Evalue=7e-13,
Organism=Escherichia coli, GI1788225, Length=209, Percent_Identity=25.3588516746411, Blast_Score=66, Evalue=6e-12,
Organism=Escherichia coli, GI1787758, Length=190, Percent_Identity=25.7894736842105, Blast_Score=62, Evalue=8e-11,
Organism=Caenorhabditis elegans, GI17553372, Length=538, Percent_Identity=37.1747211895911, Blast_Score=342, Evalue=3e-94,
Organism=Caenorhabditis elegans, GI17555318, Length=540, Percent_Identity=34.8148148148148, Blast_Score=325, Evalue=5e-89,
Organism=Caenorhabditis elegans, GI17559834, Length=554, Percent_Identity=33.5740072202166, Blast_Score=306, Evalue=2e-83,
Organism=Caenorhabditis elegans, GI17565586, Length=245, Percent_Identity=26.9387755102041, Blast_Score=71, Evalue=2e-12,
Organism=Saccharomyces cerevisiae, GI6321121, Length=557, Percent_Identity=35.7271095152603, Blast_Score=336, Evalue=9e-93,
Organism=Saccharomyces cerevisiae, GI6320874, Length=531, Percent_Identity=33.1450094161959, Blast_Score=293, Evalue=7e-80,
Organism=Saccharomyces cerevisiae, GI6325030, Length=390, Percent_Identity=29.2307692307692, Blast_Score=150, Evalue=5e-37,
Organism=Saccharomyces cerevisiae, GI6323278, Length=406, Percent_Identity=28.5714285714286, Blast_Score=144, Evalue=3e-35,
Organism=Saccharomyces cerevisiae, GI6324314, Length=403, Percent_Identity=26.7990074441687, Blast_Score=141, Evalue=4e-34,
Organism=Drosophila melanogaster, GI24666836, Length=536, Percent_Identity=38.2462686567164, Blast_Score=369, Evalue=1e-102,
Organism=Drosophila melanogaster, GI24642252, Length=523, Percent_Identity=37.6673040152964, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI18859989, Length=523, Percent_Identity=37.6673040152964, Blast_Score=340, Evalue=1e-93,
Organism=Drosophila melanogaster, GI24641342, Length=543, Percent_Identity=33.3333333333333, Blast_Score=310, Evalue=3e-84,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003439
- InterPro:   IPR017871
- InterPro:   IPR003593 [H]

Pfam domain/function: PF00005 ABC_tran [H]

EC number: NA

Molecular weight: Translated: 71094; Mature: 71094

Theoretical pI: Translated: 5.26; Mature: 5.26

Prosite motif: PS00687 ALDEHYDE_DEHYDR_GLU ; PS00211 ABC_TRANSPORTER_1 ; PS50893 ABC_TRANSPORTER_2

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.5 %Cys     (Translated Protein)
2.5 %Met     (Translated Protein)
3.0 %Cys+Met (Translated Protein)
0.5 %Cys     (Mature Protein)
2.5 %Met     (Mature Protein)
3.0 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFAMLRGELHADGGDVTV
CCCHHHHHHHCCCEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
PAQWRIAHVAQETPAVARSAVEYVIDGDTRLREIEAAIAEAQAVGDGSAEGEAHAAFADA
CCCHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
DGYTAPARAEALLLGLGFTLPQVSQPVSSFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLRRYGGNYTLFETLRLQ
CCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCEEEEECCHHHHHCCCCEEHHHHHHHH
QMAQQQAAYTRQQKEIAHLESFITRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEE
EFREPDAAPNPMMVLDGVDCGYAEADPPATILHKLALSIQNGQRIGLLGANGQGKSTLVK
EECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
TLAGTQDPLTGTLRLGKGLQIGYFAQHQLETLRDHESPLQHLARLAPDTREQELRDFLGS
HHCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHC
FNFRGDMATAPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
CCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHH
EGTLILVSHDRHLLRATADQFMLVADGTIKPFDGDLDDYRDWLLQQAAAKRNAAVAAHQG
CCEEEEEECCCHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECC
ETGGNAAAVNRKDQRRAEADERQRLAQLRKPLTKELEKVEKRMTVLQTAKAEIDQFMADE
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSYAEANKSKLMEMLKRQGEVNGELETLEEKWLELQEQIEQIE
HHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC
>Mature Secondary Structure
MIRIDQLVLQRGTKVLFDHTSVTLNPGERVGLVGANGSGKSTLFAMLRGELHADGGDVTV
CCCHHHHHHHCCCEEEEECCEEEECCCCEEEEEECCCCCHHHHHHHHHHHHCCCCCCEEE
PAQWRIAHVAQETPAVARSAVEYVIDGDTRLREIEAAIAEAQAVGDGSAEGEAHAAFADA
CCCHHHHHHHHHCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHCCCCCCCCCCCEEEECC
DGYTAPARAEALLLGLGFTLPQVSQPVSSFSGGWRMRLNLAQALMCPSDLLLLDEPTNHL
CCCCCCHHHHEEEEECCCCCHHHHHHHHHCCCCEEEEEEHHHHHHCCCCEEEEECCCCCC
DLDAIVWLEDWLARYPGTLVMISHDREFLDAICNVTVHIENQQLRRYGGNYTLFETLRLQ
CCHHHHHHHHHHHHCCCEEEEEECCHHHHHHHCCEEEEECCHHHHHCCCCEEHHHHHHHH
QMAQQQAAYTRQQKEIAHLESFITRFKAKATKARQAQSRVKALEKMERLAPVHVAAGFAF
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHEECCEEE
EFREPDAAPNPMMVLDGVDCGYAEADPPATILHKLALSIQNGQRIGLLGANGQGKSTLVK
EECCCCCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHCCCCEEEEEECCCCCHHHHHH
TLAGTQDPLTGTLRLGKGLQIGYFAQHQLETLRDHESPLQHLARLAPDTREQELRDFLGS
HHCCCCCCCCEEEECCCCCEEEHHHHHHHHHHHCCHHHHHHHHHHCCCCHHHHHHHHHHC
FNFRGDMATAPIEPFSGGEKARLALSLIVWQKPNLLLLDEPTNHLDLDTREALTMALAQF
CCCCCCCCCCCCCCCCCCCHHEEEEEEEEECCCCEEEEECCCCCCCCCHHHHHHHHHHHH
EGTLILVSHDRHLLRATADQFMLVADGTIKPFDGDLDDYRDWLLQQAAAKRNAAVAAHQG
CCEEEEEECCCHHHHHHHCCEEEEECCCCCCCCCCHHHHHHHHHHHHHHHCCCEEEEECC
ETGGNAAAVNRKDQRRAEADERQRLAQLRKPLTKELEKVEKRMTVLQTAKAEIDQFMADE
CCCCCEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCC
TSYAEANKSKLMEMLKRQGEVNGELETLEEKWLELQEQIEQIE
HHHHHCCHHHHHHHHHHCCCCCCHHHHHHHHHHHHHHHHHHCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 11206551; 11258796 [H]