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The map label for this gene is gbpR [H]

Identifier: 73541608

GI number: 73541608

Start: 2104909

End: 2105808

Strand: Direct

Name: gbpR [H]

Synonym: Reut_A1919

Alternate gene names: 73541608

Gene position: 2104909-2105808 (Clockwise)

Preceding gene: 73541604

Following gene: 73541619

Centisome position: 55.3

GC content: 67.44

Gene sequence:

>900_bases
ATGCGATTCGAGGACATCGAAGCTTTCCTGGTCGTGACCCAGCACGCCAACCTGCATCGCGCCGCCGCCGCGCTGGGCGT
GACGCAGTCCGCCCTGTCCAAGACGCTGGCGCGGCTCGAGGCAGAAGCCGGCATGCCGCTGTTCGAGCGCACGCCGCGCG
GGCTGGTACTGACCAGCGTCGGCAAGACACTGCATGCCCATGCACGCAAGATCTCGCTGGCCGCGAGCGACATGCGGCAG
GAGCTGGCCGAGCAGCGCGTCGCCAAGGCGGGCACGGTGCGGCTCGGGGCGATTCCCTATCTGGTGCCGTCGCTGCTCTC
ACCGCTGCTGGCGCAATTTTTCGTAAGCCGCCCGCTGGCCGTGTTTTCAATCGAAACCCACCTCAGCGCGCGCCTGATGG
CTGTACTGCAGAACGGCGACGTCGACCTGATCCTTGCCGCGCGACCTACCAGCGTGCCCGAGGACGTGAGCGGCCTGCCG
CTAGGCCCGCTGACGATGCAGATCGTCGCGCGCAGCGAGCATCCGCGCCGCGCGCGCTTCCGTTCGCTGGCGGACCTGAC
CGAAGAACGCTGGGCAGTGCCCGCGAGCTCGCTGTATCTGCGGCAATGGCTTGAGGAACGCTTCACGGCAGTGGGGCTCC
CACCGCCGCGCGTGGCCGTGGAAAGCACGGCGTCACCCGTCGCATTCGGCGAACTGCTGCGTCATTCGGACCTGCTCGGC
ATCATGCCGCCGCGCATCCTGAAGCAGGCGGAGGGACAGGGACTCGAAGCCATCGAAGGCCCGGACATGGCCTGGCAGCA
TGATCTGGCCATCTTCTGGCGCGCCGATGGATACCTGTCGCCGATCTGCCAGGACTTTCGCGATGCGGTGGTGAGCTGGC
GCGAGCAGGCGGATATCTGA

Upstream 100 bases:

>100_bases
CCGTGATTCCCGCGAGTACCGGCGCGATTCCCGGCAGGAATGGACAACCAATGGCAGCTACAATGCCCCGACCCCATTCT
TGCGCTCACTCGTCGACGCG

Downstream 100 bases:

>100_bases
GCCGCCTCAAACCGCCATGACAAGGTCTGCCTACGGTGCCCGGCATATTCCGACCAGATCCATTGCCGAGATGCGCTGCA
TCCGGCACACCGCCATCTGA

Product: regulatory protein, LysR:LysR, substrate-binding

Products: NA

Alternate protein names: Galactose-binding protein regulator; GBP regulator [H]

Number of amino acids: Translated: 299; Mature: 299

Protein sequence:

>299_residues
MRFEDIEAFLVVTQHANLHRAAAALGVTQSALSKTLARLEAEAGMPLFERTPRGLVLTSVGKTLHAHARKISLAASDMRQ
ELAEQRVAKAGTVRLGAIPYLVPSLLSPLLAQFFVSRPLAVFSIETHLSARLMAVLQNGDVDLILAARPTSVPEDVSGLP
LGPLTMQIVARSEHPRRARFRSLADLTEERWAVPASSLYLRQWLEERFTAVGLPPPRVAVESTASPVAFGELLRHSDLLG
IMPPRILKQAEGQGLEAIEGPDMAWQHDLAIFWRADGYLSPICQDFRDAVVSWREQADI

Sequences:

>Translated_299_residues
MRFEDIEAFLVVTQHANLHRAAAALGVTQSALSKTLARLEAEAGMPLFERTPRGLVLTSVGKTLHAHARKISLAASDMRQ
ELAEQRVAKAGTVRLGAIPYLVPSLLSPLLAQFFVSRPLAVFSIETHLSARLMAVLQNGDVDLILAARPTSVPEDVSGLP
LGPLTMQIVARSEHPRRARFRSLADLTEERWAVPASSLYLRQWLEERFTAVGLPPPRVAVESTASPVAFGELLRHSDLLG
IMPPRILKQAEGQGLEAIEGPDMAWQHDLAIFWRADGYLSPICQDFRDAVVSWREQADI
>Mature_299_residues
MRFEDIEAFLVVTQHANLHRAAAALGVTQSALSKTLARLEAEAGMPLFERTPRGLVLTSVGKTLHAHARKISLAASDMRQ
ELAEQRVAKAGTVRLGAIPYLVPSLLSPLLAQFFVSRPLAVFSIETHLSARLMAVLQNGDVDLILAARPTSVPEDVSGLP
LGPLTMQIVARSEHPRRARFRSLADLTEERWAVPASSLYLRQWLEERFTAVGLPPPRVAVESTASPVAFGELLRHSDLLG
IMPPRILKQAEGQGLEAIEGPDMAWQHDLAIFWRADGYLSPICQDFRDAVVSWREQADI

Specific function: Does not seem to be required for sbpA expression [H]

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cytoplasmic

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH lysR-type DNA-binding domain [H]

Homologues:

Organism=Escherichia coli, GI157672245, Length=248, Percent_Identity=26.2096774193548, Blast_Score=88, Evalue=6e-19,
Organism=Escherichia coli, GI87081904, Length=294, Percent_Identity=25.8503401360544, Blast_Score=80, Evalue=1e-16,
Organism=Escherichia coli, GI1790399, Length=206, Percent_Identity=28.1553398058252, Blast_Score=71, Evalue=1e-13,
Organism=Escherichia coli, GI1790208, Length=170, Percent_Identity=28.2352941176471, Blast_Score=68, Evalue=9e-13,
Organism=Escherichia coli, GI1787601, Length=261, Percent_Identity=24.904214559387, Blast_Score=62, Evalue=5e-11,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000847
- InterPro:   IPR005119
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00126 HTH_1; PF03466 LysR_substrate [H]

EC number: NA

Molecular weight: Translated: 32870; Mature: 32870

Theoretical pI: Translated: 6.97; Mature: 6.97

Prosite motif: PS50931 HTH_LYSR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.3 %Cys     (Translated Protein)
2.3 %Met     (Translated Protein)
2.7 %Cys+Met (Translated Protein)
0.3 %Cys     (Mature Protein)
2.3 %Met     (Mature Protein)
2.7 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MRFEDIEAFLVVTQHANLHRAAAALGVTQSALSKTLARLEAEAGMPLFERTPRGLVLTSV
CCCHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEHHH
GKTLHAHARKISLAASDMRQELAEQRVAKAGTVRLGAIPYLVPSLLSPLLAQFFVSRPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHCCCE
VFSIETHLSARLMAVLQNGDVDLILAARPTSVPEDVSGLPLGPLTMQIVARSEHPRRARF
EEEEHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHH
RSLADLTEERWAVPASSLYLRQWLEERFTAVGLPPPRVAVESTASPVAFGELLRHSDLLG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHCCCHH
IMPPRILKQAEGQGLEAIEGPDMAWQHDLAIFWRADGYLSPICQDFRDAVVSWREQADI
CCCHHHHHHHCCCCCCCCCCCCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC
>Mature Secondary Structure
MRFEDIEAFLVVTQHANLHRAAAALGVTQSALSKTLARLEAEAGMPLFERTPRGLVLTSV
CCCHHEEEEEEEECCCCHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHCCCCCEEEHHH
GKTLHAHARKISLAASDMRQELAEQRVAKAGTVRLGAIPYLVPSLLSPLLAQFFVSRPLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCEEECHHHHHHHHHHHHHHHHHHHHCCCE
VFSIETHLSARLMAVLQNGDVDLILAARPTSVPEDVSGLPLGPLTMQIVARSEHPRRARF
EEEEHHHHHHHHHHHHHCCCEEEEEEECCCCCCCCCCCCCCCHHHHHHHHCCCCCHHHHH
RSLADLTEERWAVPASSLYLRQWLEERFTAVGLPPPRVAVESTASPVAFGELLRHSDLLG
HHHHHHHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCCEECCCCCCHHHHHHHHHHCCCHH
IMPPRILKQAEGQGLEAIEGPDMAWQHDLAIFWRADGYLSPICQDFRDAVVSWREQADI
CCCHHHHHHHCCCCCCCCCCCCCCEECCEEEEEECCCCHHHHHHHHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 10361275 [H]