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The map label for this gene is arpC [H]

Identifier: 73541507

GI number: 73541507

Start: 1990587

End: 1992098

Strand: Direct

Name: arpC [H]

Synonym: Reut_A1818

Alternate gene names: 73541507

Gene position: 1990587-1992098 (Clockwise)

Preceding gene: 73541506

Following gene: 73541512

Centisome position: 52.29

GC content: 69.91

Gene sequence:

>1512_bases
ATGCTCAACACGTCCGCGACGGAACACCGCAAAAAGCAGCCTGCCAGGCATGGAACACTCAGACACCAGGCCGGGCGGGC
ACTGGCAACGGGGCTCGTGGTCCTGCTTGCCGGATGCGCAGCCGCCCCGCCCTATCGGCCACCCCCCATAGACCTGCCAG
ACGCCTACAAGGAGGCCGGCGCCAGCCCGGCCAGGCCCGGTGGCCCCGACGCGATCGCGCCTGACTGGTGGCGCGCCTAT
GGCGACGCGACCCTGGACCGCCTGGAAGCGCGCGTCGAGGTCTCGAGCGAGACCCTGCGCAAGGCCGTGGCGCAACTGCA
GGATGCGCAGGCCCAGGCGCGGGCCGCCAGGTCGGCCTACTTTCCTACCGTGACAGCCGGCGCGGCATTCAGCAGGAGTC
GTGTCTCTGACAATGTCGTCGGGCGATCGCTGGCGGGCAAGACCACCAATGACTACCTGCTTGGCGTGGGCGCCTCCTGG
GAGCCGGACCTGTTTGGCCGTATCGGCAGCACCGTGGATGCGGCCGAGGCGCGCGCACAGGCCAGCGCGGAAGACGTGGC
GGCCGTGCGTCTGGGCCTGCAGGCGGAGCTGGCCGACGACTACTTCGGCGTGCGCTCGCTCGATCGAGAGGCAGCACTGC
TGCAGCAGACCATCGAGGCATACACATCCGTGGTTGAGCTGGTAACGAACCGATACCGCGGCGGCATCGCCACGGAGGGC
GACGTCGCCCAGGCCCGCGCCCAGCTGGAAAGCACCCGCGCCCAGCTGTCGGACCTGCGCCTGAACCGGACGCAGCTCGA
ACACGCCCTTGCCACGCTGGTGGGCGAACCGGCAAGCCGGTTTTCGCTTGCGCCGGCTGATGGGACAGCCCATCCGGAAC
AGCTGCCGCCATTCCCGGCCGCCTTGCCCTCGCAACTGCTCGAACGCCGGCCGGATGTCGCCGCGGCCGAGCGCAGGGTG
GCGGCCGCGAATGCGCAGATCGGGGTCGCGCGGGCCGCCTTCTTCCCCAGCCTGATGCTGACGCTGGGCGGCGGCCTGGA
AAGCTCAAGCCTGGCAAGCTGGCTGACCGCACCAAGCCGCTTCTGGGCCATCGGGCCGGCATTGGCCGGCACGCTGCTGG
ACGGCGGGCGCCGCCGCGCCGGTGAAGACAGCGCCCGCGCGCAGTTTGACGCCAGCGCCGCGGACTACCGGTCCACGGTG
CTACGTGCAGTACAGGAAGTCGAAGACGGCTACGCCGCCATCCAGGCCTTGCAGGACGAAGCGCGAAGCCAGCGGATTGC
GACGCAGTCCTCTGGCCGGGCCCTGTCTATCGGGCTGGACCGCTACCGGAAAGGCGCGGTGGCCTACCTCGACGTCAATA
TCCTGCAGGCGGCCTCACTTTCCAGCGACCGCGCGCTCGAGAGTGTGCGCCGGCGTCAGTTGACGGCGAGCGTGGGGCTC
ATCAAGGCGCTCGGAGGTGGCTGGGAAGGCACGGGGCCAGTGGCGCGGTCAGTGCCACTACCGCATGAGTAA

Upstream 100 bases:

>100_bases
CGTCAACCCGGGTGACGGCCTGATGGCTGGCACCCCGGTACGTGTCGTTGCCGACCAGGCCGGTGCGGCCCGGTCGTCCT
GATCGCTTTGCCATCCCATC

Downstream 100 bases:

>100_bases
GAACCTGCGAAACCTGCGCGGCCGACGCCAGCCAGGCGCCGAACAGGATGATCACGATGCGTAGCGCGACCCATGGATTG
AGCATCAGGGCCCGTACCTG

Product: RND efflux system, outer membrane lipoprotein, NodT

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 503; Mature: 503

Protein sequence:

>503_residues
MLNTSATEHRKKQPARHGTLRHQAGRALATGLVVLLAGCAAAPPYRPPPIDLPDAYKEAGASPARPGGPDAIAPDWWRAY
GDATLDRLEARVEVSSETLRKAVAQLQDAQAQARAARSAYFPTVTAGAAFSRSRVSDNVVGRSLAGKTTNDYLLGVGASW
EPDLFGRIGSTVDAAEARAQASAEDVAAVRLGLQAELADDYFGVRSLDREAALLQQTIEAYTSVVELVTNRYRGGIATEG
DVAQARAQLESTRAQLSDLRLNRTQLEHALATLVGEPASRFSLAPADGTAHPEQLPPFPAALPSQLLERRPDVAAAERRV
AAANAQIGVARAAFFPSLMLTLGGGLESSSLASWLTAPSRFWAIGPALAGTLLDGGRRRAGEDSARAQFDASAADYRSTV
LRAVQEVEDGYAAIQALQDEARSQRIATQSSGRALSIGLDRYRKGAVAYLDVNILQAASLSSDRALESVRRRQLTASVGL
IKALGGGWEGTGPVARSVPLPHE

Sequences:

>Translated_503_residues
MLNTSATEHRKKQPARHGTLRHQAGRALATGLVVLLAGCAAAPPYRPPPIDLPDAYKEAGASPARPGGPDAIAPDWWRAY
GDATLDRLEARVEVSSETLRKAVAQLQDAQAQARAARSAYFPTVTAGAAFSRSRVSDNVVGRSLAGKTTNDYLLGVGASW
EPDLFGRIGSTVDAAEARAQASAEDVAAVRLGLQAELADDYFGVRSLDREAALLQQTIEAYTSVVELVTNRYRGGIATEG
DVAQARAQLESTRAQLSDLRLNRTQLEHALATLVGEPASRFSLAPADGTAHPEQLPPFPAALPSQLLERRPDVAAAERRV
AAANAQIGVARAAFFPSLMLTLGGGLESSSLASWLTAPSRFWAIGPALAGTLLDGGRRRAGEDSARAQFDASAADYRSTV
LRAVQEVEDGYAAIQALQDEARSQRIATQSSGRALSIGLDRYRKGAVAYLDVNILQAASLSSDRALESVRRRQLTASVGL
IKALGGGWEGTGPVARSVPLPHE
>Mature_503_residues
MLNTSATEHRKKQPARHGTLRHQAGRALATGLVVLLAGCAAAPPYRPPPIDLPDAYKEAGASPARPGGPDAIAPDWWRAY
GDATLDRLEARVEVSSETLRKAVAQLQDAQAQARAARSAYFPTVTAGAAFSRSRVSDNVVGRSLAGKTTNDYLLGVGASW
EPDLFGRIGSTVDAAEARAQASAEDVAAVRLGLQAELADDYFGVRSLDREAALLQQTIEAYTSVVELVTNRYRGGIATEG
DVAQARAQLESTRAQLSDLRLNRTQLEHALATLVGEPASRFSLAPADGTAHPEQLPPFPAALPSQLLERRPDVAAAERRV
AAANAQIGVARAAFFPSLMLTLGGGLESSSLASWLTAPSRFWAIGPALAGTLLDGGRRRAGEDSARAQFDASAADYRSTV
LRAVQEVEDGYAAIQALQDEARSQRIATQSSGRALSIGLDRYRKGAVAYLDVNILQAASLSSDRALESVRRRQLTASVGL
IKALGGGWEGTGPVARSVPLPHE

Specific function: The outer membrane component of an antibiotic efflux pump. Confers resistance to numerous structurally unrelated antibiotics such as carbenicillin, chloramphenicol, erythromycin, novobiocin, streptomycin and tetracycline. Is not involved in organic solven

COG id: NA

COG function: NA

Gene ontology:

Cell location: Cell outer membrane; Lipid-anchor (Potential) [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the outer membrane factor (OMF) (TC 1.B.17) family [H]

Homologues:

Organism=Escherichia coli, GI1786785, Length=467, Percent_Identity=29.9785867237687, Blast_Score=168, Evalue=6e-43,
Organism=Escherichia coli, GI2367348, Length=484, Percent_Identity=28.9256198347107, Blast_Score=132, Evalue=7e-32,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003423
- InterPro:   IPR010131 [H]

Pfam domain/function: PF02321 OEP [H]

EC number: NA

Molecular weight: Translated: 53179; Mature: 53179

Theoretical pI: Translated: 8.39; Mature: 8.39

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.2 %Cys     (Translated Protein)
0.4 %Met     (Translated Protein)
0.6 %Cys+Met (Translated Protein)
0.2 %Cys     (Mature Protein)
0.4 %Met     (Mature Protein)
0.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MLNTSATEHRKKQPARHGTLRHQAGRALATGLVVLLAGCAAAPPYRPPPIDLPDAYKEAG
CCCCCCHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCC
ASPARPGGPDAIAPDWWRAYGDATLDRLEARVEVSSETLRKAVAQLQDAQAQARAARSAY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPTVTAGAAFSRSRVSDNVVGRSLAGKTTNDYLLGVGASWEPDLFGRIGSTVDAAEARAQ
CCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHH
ASAEDVAAVRLGLQAELADDYFGVRSLDREAALLQQTIEAYTSVVELVTNRYRGGIATEG
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVAQARAQLESTRAQLSDLRLNRTQLEHALATLVGEPASRFSLAPADGTAHPEQLPPFPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCCCCCCCCCCCCCCH
ALPSQLLERRPDVAAAERRVAAANAQIGVARAAFFPSLMLTLGGGLESSSLASWLTAPSR
HHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHH
FWAIGPALAGTLLDGGRRRAGEDSARAQFDASAADYRSTVLRAVQEVEDGYAAIQALQDE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSQRIATQSSGRALSIGLDRYRKGAVAYLDVNILQAASLSSDRALESVRRRQLTASVGL
HHHHHHHHCCCCCEEEECHHHHHCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IKALGGGWEGTGPVARSVPLPHE
HHHHCCCCCCCCCCCCCCCCCCC
>Mature Secondary Structure
MLNTSATEHRKKQPARHGTLRHQAGRALATGLVVLLAGCAAAPPYRPPPIDLPDAYKEAG
CCCCCCHHHHHHCCHHHCCHHHHHHHHHHHHHHHHHHHHHCCCCCCCCCCCCCHHHHHCC
ASPARPGGPDAIAPDWWRAYGDATLDRLEARVEVSSETLRKAVAQLQDAQAQARAARSAY
CCCCCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHC
FPTVTAGAAFSRSRVSDNVVGRSLAGKTTNDYLLGVGASWEPDLFGRIGSTVDAAEARAQ
CCCHHCCCHHHHHHHHHHHHHHHHCCCCCCCEEEECCCCCCCHHHHHHCCCHHHHHHHHH
ASAEDVAAVRLGLQAELADDYFGVRSLDREAALLQQTIEAYTSVVELVTNRYRGGIATEG
HHHHHHHHHHHCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCCCCC
DVAQARAQLESTRAQLSDLRLNRTQLEHALATLVGEPASRFSLAPADGTAHPEQLPPFPA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHCEECCCCCCCCCCCCCCCCH
ALPSQLLERRPDVAAAERRVAAANAQIGVARAAFFPSLMLTLGGGLESSSLASWLTAPSR
HHHHHHHHCCCCHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHCCCCCHHHHHHHHCCCHH
FWAIGPALAGTLLDGGRRRAGEDSARAQFDASAADYRSTVLRAVQEVEDGYAAIQALQDE
HHHHHHHHHHHHHCCCCCCCCCCHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
ARSQRIATQSSGRALSIGLDRYRKGAVAYLDVNILQAASLSSDRALESVRRRQLTASVGL
HHHHHHHHCCCCCEEEECHHHHHCCCEEEEEHHHHHHHCCCHHHHHHHHHHHHHHHHHHH
IKALGGGWEGTGPVARSVPLPHE
HHHHCCCCCCCCCCCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 11160799 [H]