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The map label for this gene is mocR [H]

Identifier: 73541494

GI number: 73541494

Start: 1971515

End: 1973029

Strand: Direct

Name: mocR [H]

Synonym: Reut_A1805

Alternate gene names: 73541494

Gene position: 1971515-1973029 (Clockwise)

Preceding gene: 73541493

Following gene: 73541495

Centisome position: 51.79

GC content: 67.79

Gene sequence:

>1515_bases
ATGGCGCCTGGCCGCCCGCTCCGGCGGCCAGATAACCCGCGCCTTGCGCATTCTTCCTGCGAGCCCCTCCGCCTCATGGA
TGTACACCTGACGATTCACGGCCGCCAGAATCTTGCCGGCCAGCTCTATCGGCAGCTTCGCGCCGGTGTGATGGACGGGC
GCCTGGCGCCGGGGCAACGCCTGCCTTCCACGCGCGAACTGGCGCTGCGGCTCGGCGTCTCGCGCAAGACCACGCTCGAT
GTGTTCGAACGGCTGATTGCCGAGGGCTATCTGCGCTCGCGCGCCGGCGATGGCACCTTCGTCGCGGACGCCATGACGCG
GCTCGCCCCGCCGCCCACCAAGCCGGCCACTTCGCCCGCGACAGGGTCGATCTGGGACGAGATGGGCGACGCGCTGCCAA
TGACGCGCACAGAGGCCCCGCCCGACTATGACTTCGTCGGCGGCGTCACCGACAAGCGCGTGTTTCCGTTTGACCAGTGG
CGCCGCTGCGTGAGCCACGCGCTGCGAGTTCAAGCACGCGGCCGCGGCGCCTACCACGATCCGGCAGGAGAGCAGGAACT
GCGCCTGGCCGTGGCGCGCTATCTCGCCTTCAGCCGCGCCGTGGTCAGCCACTGGCAGGAGGTGATCATCACGCAGGGCG
CGCAGCAGGCACTGGACCTGTTGACAAGGGTTGCCATCCGGCCCGGCGAAGTGATTGCCATGGAAGACCCGGGCTATCCG
CCTGCACGCATCCTCTTCGCCGCGCTGGGCGCGCACGTGGTGCCGGTAGCGGTGGACGAGGAAGGCTTGATTGTCGACGC
GCTGCCACCGAATGCGCGGATGGTCTACGTCACGCCGTCTCACCAGTTTCCGCTAGGCATGCCCATGAGCCTGGAGCGCA
GGCTGGCCTTGCTGGCATGGGCTCAGCGCCACGGCGCGCTGGTGGTCGAAGACGACTACGATGGCGAATACCGCTTCGAA
GGCCGGCCCATGGAGTCGCTCAAGAGCCTGGACACCGCCGGCGTAGTGGCTTACGTGGGCACCTTTTCCAAGACCATCTT
TCCCGAACTGCGCGTGGGCTATGTCATTCCGCCCGCGCCGCTCGGCACCGCGCTGCGCCGGGCCAGGCAGGTCAGTGACT
GGCACAGCTGCACCATGACGCAAATTGCGCTCGCGAAGTTCATGCTCGATGGCTATTTCGCCAAGCACCTGCGGCGCATG
CACAAGGAGTACGCCGCGCGGCGCGCCGCATTGCTGGAGCGCTTACGCGGCGATCTGGCGCAATGGTTCACGCCGCTCCC
ATCGGCTGCAGGGATCCATCTGGTTGCCGCGATCCGGGGCCCGCACGATGAAGCCGCCATGATCAGGGTGGCTGCCACCA
GATCGGTCGGGCTTTATGGCACCGCCGGCATGTTCGCCGGCACGGCACCGCGTCCGGCGCTGTTGTTCGGCTACGGTGGC
ATCGACGTCGCTGGAGTCCAGGGCGGACTTGGCCGACTGGCAGATGCGCTGTCCGGCCACCGCGACGCAGACTGA

Upstream 100 bases:

>100_bases
GGCGATCTTTACTTCGGCCGGCTCTTCAATCAGGATTGGCTCGCCGGAAAGGGGCTGACGCCAACGCCATTTGCGCGCAT
GGCGCCCCGCGCGGGCTAGC

Downstream 100 bases:

>100_bases
ACGACGGCTGCGACAGGGCGGCCCCGCGGCAACCGGTTACCTAAAAATCGTAAAAATCGGCCATTTTGCATAACCAGTTG
GCGTCCTACTCTTGTTCCCA

Product: GntR family transcriptional regulator

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 504; Mature: 503

Protein sequence:

>504_residues
MAPGRPLRRPDNPRLAHSSCEPLRLMDVHLTIHGRQNLAGQLYRQLRAGVMDGRLAPGQRLPSTRELALRLGVSRKTTLD
VFERLIAEGYLRSRAGDGTFVADAMTRLAPPPTKPATSPATGSIWDEMGDALPMTRTEAPPDYDFVGGVTDKRVFPFDQW
RRCVSHALRVQARGRGAYHDPAGEQELRLAVARYLAFSRAVVSHWQEVIITQGAQQALDLLTRVAIRPGEVIAMEDPGYP
PARILFAALGAHVVPVAVDEEGLIVDALPPNARMVYVTPSHQFPLGMPMSLERRLALLAWAQRHGALVVEDDYDGEYRFE
GRPMESLKSLDTAGVVAYVGTFSKTIFPELRVGYVIPPAPLGTALRRARQVSDWHSCTMTQIALAKFMLDGYFAKHLRRM
HKEYAARRAALLERLRGDLAQWFTPLPSAAGIHLVAAIRGPHDEAAMIRVAATRSVGLYGTAGMFAGTAPRPALLFGYGG
IDVAGVQGGLGRLADALSGHRDAD

Sequences:

>Translated_504_residues
MAPGRPLRRPDNPRLAHSSCEPLRLMDVHLTIHGRQNLAGQLYRQLRAGVMDGRLAPGQRLPSTRELALRLGVSRKTTLD
VFERLIAEGYLRSRAGDGTFVADAMTRLAPPPTKPATSPATGSIWDEMGDALPMTRTEAPPDYDFVGGVTDKRVFPFDQW
RRCVSHALRVQARGRGAYHDPAGEQELRLAVARYLAFSRAVVSHWQEVIITQGAQQALDLLTRVAIRPGEVIAMEDPGYP
PARILFAALGAHVVPVAVDEEGLIVDALPPNARMVYVTPSHQFPLGMPMSLERRLALLAWAQRHGALVVEDDYDGEYRFE
GRPMESLKSLDTAGVVAYVGTFSKTIFPELRVGYVIPPAPLGTALRRARQVSDWHSCTMTQIALAKFMLDGYFAKHLRRM
HKEYAARRAALLERLRGDLAQWFTPLPSAAGIHLVAAIRGPHDEAAMIRVAATRSVGLYGTAGMFAGTAPRPALLFGYGG
IDVAGVQGGLGRLADALSGHRDAD
>Mature_503_residues
APGRPLRRPDNPRLAHSSCEPLRLMDVHLTIHGRQNLAGQLYRQLRAGVMDGRLAPGQRLPSTRELALRLGVSRKTTLDV
FERLIAEGYLRSRAGDGTFVADAMTRLAPPPTKPATSPATGSIWDEMGDALPMTRTEAPPDYDFVGGVTDKRVFPFDQWR
RCVSHALRVQARGRGAYHDPAGEQELRLAVARYLAFSRAVVSHWQEVIITQGAQQALDLLTRVAIRPGEVIAMEDPGYPP
ARILFAALGAHVVPVAVDEEGLIVDALPPNARMVYVTPSHQFPLGMPMSLERRLALLAWAQRHGALVVEDDYDGEYRFEG
RPMESLKSLDTAGVVAYVGTFSKTIFPELRVGYVIPPAPLGTALRRARQVSDWHSCTMTQIALAKFMLDGYFAKHLRRMH
KEYAARRAALLERLRGDLAQWFTPLPSAAGIHLVAAIRGPHDEAAMIRVAATRSVGLYGTAGMFAGTAPRPALLFGYGGI
DVAGVQGGLGRLADALSGHRDAD

Specific function: Could play a regulatory role in the transcription of the moc genes for rhizopine catabolism. Could also have an aminotransferase activity [H]

COG id: COG1167

COG function: function code KE; Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Unknown [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 HTH gntR-type DNA-binding domain [H]

Homologues:

Organism=Homo sapiens, GI7705897, Length=293, Percent_Identity=26.962457337884, Blast_Score=108, Evalue=1e-23,
Organism=Homo sapiens, GI33469970, Length=293, Percent_Identity=26.962457337884, Blast_Score=108, Evalue=1e-23,
Organism=Escherichia coli, GI1790797, Length=385, Percent_Identity=30.1298701298701, Blast_Score=138, Evalue=1e-33,
Organism=Escherichia coli, GI1787710, Length=375, Percent_Identity=27.2, Blast_Score=133, Evalue=3e-32,

Paralogues:

None

Copy number: 10-20 Molecules/Cell [C]

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR004839
- InterPro:   IPR000524
- InterPro:   IPR015424
- InterPro:   IPR015421
- InterPro:   IPR011991 [H]

Pfam domain/function: PF00155 Aminotran_1_2; PF00392 GntR [H]

EC number: NA

Molecular weight: Translated: 55102; Mature: 54971

Theoretical pI: Translated: 9.74; Mature: 9.74

Prosite motif: PS50949 HTH_GNTR

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.2 %Met     (Translated Protein)
3.8 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.0 %Met     (Mature Protein)
3.6 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MAPGRPLRRPDNPRLAHSSCEPLRLMDVHLTIHGRQNLAGQLYRQLRAGVMDGRLAPGQR
CCCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
LPSTRELALRLGVSRKTTLDVFERLIAEGYLRSRAGDGTFVADAMTRLAPPPTKPATSPA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
TGSIWDEMGDALPMTRTEAPPDYDFVGGVTDKRVFPFDQWRRCVSHALRVQARGRGAYHD
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PAGEQELRLAVARYLAFSRAVVSHWQEVIITQGAQQALDLLTRVAIRPGEVIAMEDPGYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCC
PARILFAALGAHVVPVAVDEEGLIVDALPPNARMVYVTPSHQFPLGMPMSLERRLALLAW
HHHHHHHHHCCCEEEEEECCCCEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
AQRHGALVVEDDYDGEYRFEGRPMESLKSLDTAGVVAYVGTFSKTIFPELRVGYVIPPAP
HHHCCCEEEECCCCCCEEECCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCC
LGTALRRARQVSDWHSCTMTQIALAKFMLDGYFAKHLRRMHKEYAARRAALLERLRGDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWFTPLPSAAGIHLVAAIRGPHDEAAMIRVAATRSVGLYGTAGMFAGTAPRPALLFGYGG
HHHCCCCCCCCEEEEEEECCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCC
IDVAGVQGGLGRLADALSGHRDAD
CEEECCCCCHHHHHHHHCCCCCCC
>Mature Secondary Structure 
APGRPLRRPDNPRLAHSSCEPLRLMDVHLTIHGRQNLAGQLYRQLRAGVMDGRLAPGQR
CCCCCCCCCCCCCCCCCCCCCEEEEEEEEEEECCHHHHHHHHHHHHHHHCCCCCCCCCC
LPSTRELALRLGVSRKTTLDVFERLIAEGYLRSRAGDGTFVADAMTRLAPPPTKPATSPA
CCCHHHHHHHHCCCCCHHHHHHHHHHHHHHHHHCCCCCCHHHHHHHHCCCCCCCCCCCCC
TGSIWDEMGDALPMTRTEAPPDYDFVGGVTDKRVFPFDQWRRCVSHALRVQARGRGAYHD
CCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHHCCCCCCCC
PAGEQELRLAVARYLAFSRAVVSHWQEVIITQGAQQALDLLTRVAIRPGEVIAMEDPGYP
CCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHHHHHCCCCCEEEECCCCCC
PARILFAALGAHVVPVAVDEEGLIVDALPPNARMVYVTPSHQFPLGMPMSLERRLALLAW
HHHHHHHHHCCCEEEEEECCCCEEEECCCCCCEEEEECCCCCCCCCCCCCHHHHHHHHHH
AQRHGALVVEDDYDGEYRFEGRPMESLKSLDTAGVVAYVGTFSKTIFPELRVGYVIPPAP
HHHCCCEEEECCCCCCEEECCCCHHHHHCCCHHHHHHHHHHHHHHHCCCCCCCEEECCCC
LGTALRRARQVSDWHSCTMTQIALAKFMLDGYFAKHLRRMHKEYAARRAALLERLRGDLA
HHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QWFTPLPSAAGIHLVAAIRGPHDEAAMIRVAATRSVGLYGTAGMFAGTAPRPALLFGYGG
HHHCCCCCCCCEEEEEEECCCCCCHHEEEEEECCCCCCCCCCCCCCCCCCCCEEEEECCC
IDVAGVQGGLGRLADALSGHRDAD
CEEECCCCCHHHHHHHHCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: DNA [C]

Specific reaction: Protein + DNA = Protein-DNA [C]

General reaction: NA

Inhibitor: NA

Structure determination priority: 9.0

TargetDB status: NA

Availability: NA

References: 7845353 [H]