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The map label for this gene is mrkC [H]

Identifier: 73541385

GI number: 73541385

Start: 1829327

End: 1831945

Strand: Direct

Name: mrkC [H]

Synonym: Reut_A1696

Alternate gene names: 73541385

Gene position: 1829327-1831945 (Clockwise)

Preceding gene: 73541384

Following gene: 73541386

Centisome position: 48.06

GC content: 65.02

Gene sequence:

>2619_bases
ATGCAAGTCAGAAGAAGGCAGCGCCTGTTTCCTTCCCGTCTGCGCCCGTGCTGCGTGGTGGTGCTCTCGCTAATCAGCAT
TTCGACCGCCCGTGCAACCACGACTGGCTCCGGGGACGTGGAATTCAATGACGTATTCCTGCGGCAGCCCGGTGGCGGCA
AGCTTGATGTGTCGCGCTTCAACCGAGGGAACGTGCCGTTGCCGGGGACCTATCGTGCCGACTTGCAGGTCAACGGGGCG
TGGGTTGGCATGGCCGAGATCACACTGCGGCAGGCGGGGAATGGTGCACGCGATGTCCAACCCTGTTTTGACCGCATGCT
GATCGAACGCGCAGGGGTGGACGTTACGCGGTTGCCGGCCCCATCCGCCGAGCGTCTTGTTCATGCAGCCATGGCGGACT
GCGTGACGTTGCCGGAGCTGGTTCCCGGCGCGAACGCCGCCTTTGACAATGGCGAACTGCGGCTCGATCTGAGCGTGCCG
CAGTCGTTCCTGAGCCGTAGCGCGCGTGGCTATGTCGATCCGCGCTACTGGGACGAGGGTGTCACTGCTGCGCGCCTGGC
GTACAACGCCAACGTGTATCACACGGAGAGCACCGGAGTTTCGTCAACGCAGGGCTATCTCGGCCTGAATGCGGGCATCA
ACATCGGTCCCTGGCGTTTCCGGCACTATGGCAGCCTTTCGTACGATGCGGTCGCCGGCAATCGCTACCAGTCGGTGCAG
ACCAGCGTACAGCGCTCGATCACGCCGATGCGCAGCCAACTGGTGGTGGGGGATGCGTTTACGGACGGCGCCATGTTCGA
CAGCTTCGGCTTCCGCGGCGTGCAGTTCGCCACCGACGATCGCATGCTGCCCGAATCGCAGCGCGGCTACGCGCCGACAG
TCCGGGGCATCGCCAACAGCAACGCGTGGGTGCAGGTACGGCAAAACGGCAACATCATCTACGAGACCACCGTCGCGCCA
GGCACGTTCGAGATCGACGATCTCTACGCAACCGGCTACGGCGGCGACCTGGAAGTGCTGGTGACCGAGGCGGACGGCAG
TGTCCGTGCCTCGTTCGTGCCTTACGCGCCCGTCGTGAACGCGTTGCGCCCCGGCATCTGGCGCTATAGCGTGACATCGG
GCCAGTATCGCAACACCGGCGTGCAAAGTACCCCGCTTTTCCTGCAGGCAACCGTGCAGCACGGCATCTCCAACCTGTTG
ACTGGCTATGGCGGAATGCTCGCTGCTCAAGGCTATTTCTCGATCGTCCTCGGCATGGCGATGAACACGCGCTACGGCGC
ATTCGGCGCTGACGCTACCCATGCCACCACGCGCCTGGTCAGCCAGCCCGACCGTAGTGGCCAGAGCATGCGCTTGTCCT
ACAGCAAAATGGTCTCGCCCACGCGCACCAACGTGACGCTGGCCGCCTACCGGTACTCCACGAGCGGCTTTCTGAACTTT
GCCGATGCAGTGGCAACGCGCAGCCTCGATGACGCGGGCGCCGTCCCCGTGCCTGGCGGCGTCCGGCGCGGGCGCCTGCA
AGTCACCATCAGCCAGGGCATGCCGGCAGGATACGGCAACGTCTACCTGTCAGGATCCGCGCAGGACTACTGGAACCACC
GCGGCCGGGACACCCAGTACCAGGCCGGGTACAACAACAGCTACAAGCGTGTCAGCTACGGCATCTCGGCAGCACGGCAG
ATCAACCTGGGCACCGCCAGGTGGGAGAACCGCGTCATGCTCACGGTCGGCATACCGTTGGGCAGGACACCGCACGCCCC
GTATGCGATGACGAGTCTGCAGAAGGACTCGTCCGGTGTCATGGGCGTTCAGGAATCCCTGACCGGCACGCTCGGCGCGG
ACAGCAAATTCACGTATGGACTCAACGCGAGCCACAGCAGTGGCGGTGGCACCGTCACCAGCAGCGTCGCCGGCAATGCG
GGCTATGTCTCGCCAATTGCGACGCTGACCGCCAACGCGAGCCACGGCAACCACTACAGCCAGTACGGCGCCGGCATCTC
CGGCGGCATCGTCGCTTATGCCGGCGGGGTGACGTTCTCGTCGGCGCTCGGCGATACCGTCGCCATCGTGGAGGCTGCGG
ACGCTACCGGCGCGCGCGTAGCCAATGCCAATGGACTGCGGCTCGATCCGTGGGGCCATGCGATCGTGCCAAACCTGATG
CCGTTCTCGCGCAATCCCGTCGAGATCGACCCCAAGGGCCTTCCGCTCGATGTGGAGCTGCGTTCGACGCTGCAGCAGGT
GGCGCCAACGTCGGGAGCCGTGGTCCGTGTACGGTTCGATACCGGCAAAGGTGGCCGGGCGGCGATCCTGCGCGTGCGCA
TGAGTGACGGCACGCCGTTGCCGTTCGCCGCCGAGGTATTCGATGCCGACGGGAACCTTGCGGGAACCGTCGGCCAGGAC
GGGCAACTCCTGGCGCGCGGGCTGACACGGGACGCCGGTGTGCTGACAGCAAAATGGGGACCGCTGCAGGCGGACACTTG
CGCCTTCCGCTATGCACTGCCGGCGTCTACGGGCAATCCGGGACGCGCATTACCCCGCGCCGACGGTGTATGCGGCGACC
ACGCTTCGGCTACGGTGTCCATGAAGCGCAATCATCCGGATGCACAAGGAGCGCAATGA

Upstream 100 bases:

>100_bases
GAACGATGGCGAAGCGCCACTGGACGACGCCAGGTAGCCGTGCTGGTCCGCAGGTGCCGCGACGGCCGCGCGCCGAACCG
ACCGGCTCCAGGAAATCTCA

Downstream 100 bases:

>100_bases
TGGCCGTGCTCGACGTCAGCGCGGGAGCACAGGCGGCGCTCCGCAGCCTGCTCGCCGCGATGCTGCTGCTGGTATCGCAG
GCAGCCCATGCGGCCTGCAC

Product: fimbrial biogenesis outer membrane usher protein

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 872; Mature: 872

Protein sequence:

>872_residues
MQVRRRQRLFPSRLRPCCVVVLSLISISTARATTTGSGDVEFNDVFLRQPGGGKLDVSRFNRGNVPLPGTYRADLQVNGA
WVGMAEITLRQAGNGARDVQPCFDRMLIERAGVDVTRLPAPSAERLVHAAMADCVTLPELVPGANAAFDNGELRLDLSVP
QSFLSRSARGYVDPRYWDEGVTAARLAYNANVYHTESTGVSSTQGYLGLNAGINIGPWRFRHYGSLSYDAVAGNRYQSVQ
TSVQRSITPMRSQLVVGDAFTDGAMFDSFGFRGVQFATDDRMLPESQRGYAPTVRGIANSNAWVQVRQNGNIIYETTVAP
GTFEIDDLYATGYGGDLEVLVTEADGSVRASFVPYAPVVNALRPGIWRYSVTSGQYRNTGVQSTPLFLQATVQHGISNLL
TGYGGMLAAQGYFSIVLGMAMNTRYGAFGADATHATTRLVSQPDRSGQSMRLSYSKMVSPTRTNVTLAAYRYSTSGFLNF
ADAVATRSLDDAGAVPVPGGVRRGRLQVTISQGMPAGYGNVYLSGSAQDYWNHRGRDTQYQAGYNNSYKRVSYGISAARQ
INLGTARWENRVMLTVGIPLGRTPHAPYAMTSLQKDSSGVMGVQESLTGTLGADSKFTYGLNASHSSGGGTVTSSVAGNA
GYVSPIATLTANASHGNHYSQYGAGISGGIVAYAGGVTFSSALGDTVAIVEAADATGARVANANGLRLDPWGHAIVPNLM
PFSRNPVEIDPKGLPLDVELRSTLQQVAPTSGAVVRVRFDTGKGGRAAILRVRMSDGTPLPFAAEVFDADGNLAGTVGQD
GQLLARGLTRDAGVLTAKWGPLQADTCAFRYALPASTGNPGRALPRADGVCGDHASATVSMKRNHPDAQGAQ

Sequences:

>Translated_872_residues
MQVRRRQRLFPSRLRPCCVVVLSLISISTARATTTGSGDVEFNDVFLRQPGGGKLDVSRFNRGNVPLPGTYRADLQVNGA
WVGMAEITLRQAGNGARDVQPCFDRMLIERAGVDVTRLPAPSAERLVHAAMADCVTLPELVPGANAAFDNGELRLDLSVP
QSFLSRSARGYVDPRYWDEGVTAARLAYNANVYHTESTGVSSTQGYLGLNAGINIGPWRFRHYGSLSYDAVAGNRYQSVQ
TSVQRSITPMRSQLVVGDAFTDGAMFDSFGFRGVQFATDDRMLPESQRGYAPTVRGIANSNAWVQVRQNGNIIYETTVAP
GTFEIDDLYATGYGGDLEVLVTEADGSVRASFVPYAPVVNALRPGIWRYSVTSGQYRNTGVQSTPLFLQATVQHGISNLL
TGYGGMLAAQGYFSIVLGMAMNTRYGAFGADATHATTRLVSQPDRSGQSMRLSYSKMVSPTRTNVTLAAYRYSTSGFLNF
ADAVATRSLDDAGAVPVPGGVRRGRLQVTISQGMPAGYGNVYLSGSAQDYWNHRGRDTQYQAGYNNSYKRVSYGISAARQ
INLGTARWENRVMLTVGIPLGRTPHAPYAMTSLQKDSSGVMGVQESLTGTLGADSKFTYGLNASHSSGGGTVTSSVAGNA
GYVSPIATLTANASHGNHYSQYGAGISGGIVAYAGGVTFSSALGDTVAIVEAADATGARVANANGLRLDPWGHAIVPNLM
PFSRNPVEIDPKGLPLDVELRSTLQQVAPTSGAVVRVRFDTGKGGRAAILRVRMSDGTPLPFAAEVFDADGNLAGTVGQD
GQLLARGLTRDAGVLTAKWGPLQADTCAFRYALPASTGNPGRALPRADGVCGDHASATVSMKRNHPDAQGAQ
>Mature_872_residues
MQVRRRQRLFPSRLRPCCVVVLSLISISTARATTTGSGDVEFNDVFLRQPGGGKLDVSRFNRGNVPLPGTYRADLQVNGA
WVGMAEITLRQAGNGARDVQPCFDRMLIERAGVDVTRLPAPSAERLVHAAMADCVTLPELVPGANAAFDNGELRLDLSVP
QSFLSRSARGYVDPRYWDEGVTAARLAYNANVYHTESTGVSSTQGYLGLNAGINIGPWRFRHYGSLSYDAVAGNRYQSVQ
TSVQRSITPMRSQLVVGDAFTDGAMFDSFGFRGVQFATDDRMLPESQRGYAPTVRGIANSNAWVQVRQNGNIIYETTVAP
GTFEIDDLYATGYGGDLEVLVTEADGSVRASFVPYAPVVNALRPGIWRYSVTSGQYRNTGVQSTPLFLQATVQHGISNLL
TGYGGMLAAQGYFSIVLGMAMNTRYGAFGADATHATTRLVSQPDRSGQSMRLSYSKMVSPTRTNVTLAAYRYSTSGFLNF
ADAVATRSLDDAGAVPVPGGVRRGRLQVTISQGMPAGYGNVYLSGSAQDYWNHRGRDTQYQAGYNNSYKRVSYGISAARQ
INLGTARWENRVMLTVGIPLGRTPHAPYAMTSLQKDSSGVMGVQESLTGTLGADSKFTYGLNASHSSGGGTVTSSVAGNA
GYVSPIATLTANASHGNHYSQYGAGISGGIVAYAGGVTFSSALGDTVAIVEAADATGARVANANGLRLDPWGHAIVPNLM
PFSRNPVEIDPKGLPLDVELRSTLQQVAPTSGAVVRVRFDTGKGGRAAILRVRMSDGTPLPFAAEVFDADGNLAGTVGQD
GQLLARGLTRDAGVLTAKWGPLQADTCAFRYALPASTGNPGRALPRADGVCGDHASATVSMKRNHPDAQGAQ

Specific function: Involved in the export and assembly of the type 3 fimbrial subunit (mrkA) [H]

COG id: COG3188

COG function: function code NU; P pilus assembly protein, porin PapC

Gene ontology:

Cell location: Cell outer membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the fimbrial export usher family [H]

Homologues:

Organism=Escherichia coli, GI1786332, Length=806, Percent_Identity=35.3598014888337, Blast_Score=469, Evalue=1e-133,
Organism=Escherichia coli, GI1790772, Length=869, Percent_Identity=34.0621403912543, Blast_Score=463, Evalue=1e-131,
Organism=Escherichia coli, GI1789533, Length=845, Percent_Identity=34.2011834319527, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1787172, Length=839, Percent_Identity=34.207389749702, Blast_Score=443, Evalue=1e-125,
Organism=Escherichia coli, GI1786744, Length=831, Percent_Identity=34.0553549939832, Blast_Score=436, Evalue=1e-123,
Organism=Escherichia coli, GI1788427, Length=760, Percent_Identity=33.6842105263158, Blast_Score=407, Evalue=1e-114,
Organism=Escherichia coli, GI87081778, Length=801, Percent_Identity=26.9662921348315, Blast_Score=216, Evalue=5e-57,
Organism=Escherichia coli, GI1789610, Length=821, Percent_Identity=24.7259439707674, Blast_Score=139, Evalue=9e-34,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR000015
- InterPro:   IPR018030 [H]

Pfam domain/function: PF00577 Usher [H]

EC number: NA

Molecular weight: Translated: 92613; Mature: 92613

Theoretical pI: Translated: 9.36; Mature: 9.36

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.7 %Cys     (Translated Protein)
2.2 %Met     (Translated Protein)
2.9 %Cys+Met (Translated Protein)
0.7 %Cys     (Mature Protein)
2.2 %Met     (Mature Protein)
2.9 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MQVRRRQRLFPSRLRPCCVVVLSLISISTARATTTGSGDVEFNDVFLRQPGGGKLDVSRF
CCCCHHHHCCHHHCCHHHHHHHHHHHHHHHCEECCCCCCEEEEEEEEECCCCCEEEHEEC
NRGNVPLPGTYRADLQVNGAWVGMAEITLRQAGNGARDVQPCFDRMLIERAGVDVTRLPA
CCCCCCCCCCEEEEEEECCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCC
PSAERLVHAAMADCVTLPELVPGANAAFDNGELRLDLSVPQSFLSRSARGYVDPRYWDEG
CCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCHHHHHCCCCCCCCCHHCCCC
VTAARLAYNANVYHTESTGVSSTQGYLGLNAGINIGPWRFRHYGSLSYDAVAGNRYQSVQ
CCEEEEEECCEEEEECCCCCCCCCCEEEECCCCCCCCEEEEECCCCCEEEECCCCHHHHH
TSVQRSITPMRSQLVVGDAFTDGAMFDSFGFRGVQFATDDRMLPESQRGYAPTVRGIANS
HHHHHHCCCCHHEEEEECCCCCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
NAWVQVRQNGNIIYETTVAPGTFEIDDLYATGYGGDLEVLVTEADGSVRASFVPYAPVVN
CCEEEEECCCCEEEEEECCCCEEEECCEEEECCCCCEEEEEEECCCCEEEEECCHHHHHH
ALRPGIWRYSVTSGQYRNTGVQSTPLFLQATVQHGISNLLTGYGGMLAAQGYFSIVLGMA
HHCCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MNTRYGAFGADATHATTRLVSQPDRSGQSMRLSYSKMVSPTRTNVTLAAYRYSTSGFLNF
HCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCEEEEEEEECCCCCHHH
ADAVATRSLDDAGAVPVPGGVRRGRLQVTISQGMPAGYGNVYLSGSAQDYWNHRGRDTQY
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHCCCCCCEE
QAGYNNSYKRVSYGISAARQINLGTARWENRVMLTVGIPLGRTPHAPYAMTSLQKDSSGV
ECCCCCCCEEEECCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCC
MGVQESLTGTLGADSKFTYGLNASHSSGGGTVTSSVAGNAGYVSPIATLTANASHGNHYS
CEEHHHHCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHH
QYGAGISGGIVAYAGGVTFSSALGDTVAIVEAADATGARVANANGLRLDPWGHAIVPNLM
HHCCCCCCCEEEEECCCEEHHHCCCEEEEEEECCCCCCEEECCCCCEECCCCCCCCCCCC
PFSRNPVEIDPKGLPLDVELRSTLQQVAPTSGAVVRVRFDTGKGGRAAILRVRMSDGTPL
CCCCCCCEECCCCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCC
PFAAEVFDADGNLAGTVGQDGQLLARGLTRDAGVLTAKWGPLQADTCAFRYALPASTGNP
CEEHEEECCCCCEEEECCCCCHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCC
GRALPRADGVCGDHASATVSMKRNHPDAQGAQ
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC
>Mature Secondary Structure
MQVRRRQRLFPSRLRPCCVVVLSLISISTARATTTGSGDVEFNDVFLRQPGGGKLDVSRF
CCCCHHHHCCHHHCCHHHHHHHHHHHHHHHCEECCCCCCEEEEEEEEECCCCCEEEHEEC
NRGNVPLPGTYRADLQVNGAWVGMAEITLRQAGNGARDVQPCFDRMLIERAGVDVTRLPA
CCCCCCCCCCEEEEEEECCEEEEEEEEEEECCCCCCCHHHHHHHHHHHHHCCCCEEECCC
PSAERLVHAAMADCVTLPELVPGANAAFDNGELRLDLSVPQSFLSRSARGYVDPRYWDEG
CCHHHHHHHHHHHHHHHHHHCCCCCCEECCCCEEEEECCCHHHHHCCCCCCCCCHHCCCC
VTAARLAYNANVYHTESTGVSSTQGYLGLNAGINIGPWRFRHYGSLSYDAVAGNRYQSVQ
CCEEEEEECCEEEEECCCCCCCCCCEEEECCCCCCCCEEEEECCCCCEEEECCCCHHHHH
TSVQRSITPMRSQLVVGDAFTDGAMFDSFGFRGVQFATDDRMLPESQRGYAPTVRGIANS
HHHHHHCCCCHHEEEEECCCCCCCHHHCCCCCCEEEECCCCCCCCCCCCCCCCCCCCCCC
NAWVQVRQNGNIIYETTVAPGTFEIDDLYATGYGGDLEVLVTEADGSVRASFVPYAPVVN
CCEEEEECCCCEEEEEECCCCEEEECCEEEECCCCCEEEEEEECCCCEEEEECCHHHHHH
ALRPGIWRYSVTSGQYRNTGVQSTPLFLQATVQHGISNLLTGYGGMLAAQGYFSIVLGMA
HHCCCCEEEEECCCCCCCCCCCCCCCEEHHHHHHHHHHHHHCCCCHHHHHHHHHHHHHHH
MNTRYGAFGADATHATTRLVSQPDRSGQSMRLSYSKMVSPTRTNVTLAAYRYSTSGFLNF
HCCCCCCCCCCCHHHHHHHHCCCCCCCCEEEEEHHHHCCCCCCCEEEEEEEECCCCCHHH
ADAVATRSLDDAGAVPVPGGVRRGRLQVTISQGMPAGYGNVYLSGSAQDYWNHRGRDTQY
HHHHHHCCCCCCCCCCCCCCCCCCEEEEEEECCCCCCCCCEEEECCCHHHHHCCCCCCEE
QAGYNNSYKRVSYGISAARQINLGTARWENRVMLTVGIPLGRTPHAPYAMTSLQKDSSGV
ECCCCCCCEEEECCCCCEEEEECCCCCCCCEEEEEEECCCCCCCCCCHHHHHCCCCCCCC
MGVQESLTGTLGADSKFTYGLNASHSSGGGTVTSSVAGNAGYVSPIATLTANASHGNHYS
CEEHHHHCCCCCCCCEEEEECCCCCCCCCCEEEECCCCCCCCCCCEEEEEECCCCCCCHH
QYGAGISGGIVAYAGGVTFSSALGDTVAIVEAADATGARVANANGLRLDPWGHAIVPNLM
HHCCCCCCCEEEEECCCEEHHHCCCEEEEEEECCCCCCEEECCCCCEECCCCCCCCCCCC
PFSRNPVEIDPKGLPLDVELRSTLQQVAPTSGAVVRVRFDTGKGGRAAILRVRMSDGTPL
CCCCCCCEECCCCCEEEHHHHHHHHHHCCCCCCEEEEEEECCCCCCEEEEEEEECCCCCC
PFAAEVFDADGNLAGTVGQDGQLLARGLTRDAGVLTAKWGPLQADTCAFRYALPASTGNP
CEEHEEECCCCCEEEECCCCCHHHHHCCCCCCCEEEECCCCCCCCCEEEEEEECCCCCCC
GRALPRADGVCGDHASATVSMKRNHPDAQGAQ
CCCCCCCCCCCCCCCCEEEEEECCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Alpha Beta

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 1670938 [H]