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The map label for this gene is tauD [H]

Identifier: 73541292

GI number: 73541292

Start: 1724919

End: 1725764

Strand: Direct

Name: tauD [H]

Synonym: Reut_A1602

Alternate gene names: 73541292

Gene position: 1724919-1725764 (Clockwise)

Preceding gene: 73541289

Following gene: 73541293

Centisome position: 45.31

GC content: 61.82

Gene sequence:

>846_bases
ATGAAGATCAGGCAAATCACCCCGGCCATTGGTGCCGAGATTTCCGGCGTCAACCTTGGCGAGGGGGCGCGCGATCCGGC
ACTGTTTGCCGAAATCAAGGCGGCGTTGCTCAAGCACCGCGTGCTCTTCTTTCGCAAGCAGGAGATCACTCGCGCCGATC
ATGTGGCCTTCGCAAGCGCTTTCGGCAAGCTCGAAGACCATCCGGTTGTCGGCAGCGTTCCTGATCACCCGGGCCTCGTG
AAGGTCTATCGCAGCGACAACCCGCACAGCTACGAGAACAGCTATCACTGCGACGGCCTGTGGCGTCCCAACCCGGCCAT
GGGCGCGGTGCTGCGCTGCCTCGAATGTCCGGAGATCGGCGGCGACACCATCTGGGTCAACATGGTAAAGGCGTACGATG
AACTGCCTGAAGAGATCAAGAGGAAGATCAACGGCCTACGCGCCAGGGCCAGCATCGAACACAGCTTCGGCGCAGTCATG
ACGCCTGAAAATCGCGCCAAGCTGGCCCAGGATCATCCTGCGGTGGAGCATCCAGTGGTGCGCACCCATCCGGAGACCGG
GGAGAAGATCCTGTTCGTCGGCGCCTCGTTCACGACGCATTTCACCAACTACAGTACGCCGGACAACGTGCGCCACGGCA
TCGACAAGTCGCCCGGCGCGTCCCTCCTGCTCAACTACCTGACTAGCCGCGCCACCATTCCCGAGTACCAGGTGCGCTGG
GCCTGGCAGGAGGGCGATGTTGCAGTGTGGGACAACCGCAGCACGCAGCACTATGCGGTCAACGACTACTATCCGGCGCC
GCGCAAGATGGAGCGCGCGGGAATAGTGGGTGATATCCCATACTGA

Upstream 100 bases:

>100_bases
CAATGTCCTGAGCAAATAAGCATGGAAGCCTGGAAGGCCAGATACTTGCTCACCAGAAAGTCGGACAGACAGAATCAACC
GGACTGCAGGAGACATAGCA

Downstream 100 bases:

>100_bases
TTCGAAACTGGGCCAGCAGAACGACTTGATGCGCGCCATGCGCAACGGCACAAGGGCACCATGAAGGCGATCTGGTACGA
AAAACAAGGGCGGGCGGAAG

Product: taurine dioxygenase

Products: NA

Alternate protein names: 2-aminoethanesulfonate dioxygenase; Sulfate starvation-induced protein 3; SSI3 [H]

Number of amino acids: Translated: 281; Mature: 281

Protein sequence:

>281_residues
MKIRQITPAIGAEISGVNLGEGARDPALFAEIKAALLKHRVLFFRKQEITRADHVAFASAFGKLEDHPVVGSVPDHPGLV
KVYRSDNPHSYENSYHCDGLWRPNPAMGAVLRCLECPEIGGDTIWVNMVKAYDELPEEIKRKINGLRARASIEHSFGAVM
TPENRAKLAQDHPAVEHPVVRTHPETGEKILFVGASFTTHFTNYSTPDNVRHGIDKSPGASLLLNYLTSRATIPEYQVRW
AWQEGDVAVWDNRSTQHYAVNDYYPAPRKMERAGIVGDIPY

Sequences:

>Translated_281_residues
MKIRQITPAIGAEISGVNLGEGARDPALFAEIKAALLKHRVLFFRKQEITRADHVAFASAFGKLEDHPVVGSVPDHPGLV
KVYRSDNPHSYENSYHCDGLWRPNPAMGAVLRCLECPEIGGDTIWVNMVKAYDELPEEIKRKINGLRARASIEHSFGAVM
TPENRAKLAQDHPAVEHPVVRTHPETGEKILFVGASFTTHFTNYSTPDNVRHGIDKSPGASLLLNYLTSRATIPEYQVRW
AWQEGDVAVWDNRSTQHYAVNDYYPAPRKMERAGIVGDIPY
>Mature_281_residues
MKIRQITPAIGAEISGVNLGEGARDPALFAEIKAALLKHRVLFFRKQEITRADHVAFASAFGKLEDHPVVGSVPDHPGLV
KVYRSDNPHSYENSYHCDGLWRPNPAMGAVLRCLECPEIGGDTIWVNMVKAYDELPEEIKRKINGLRARASIEHSFGAVM
TPENRAKLAQDHPAVEHPVVRTHPETGEKILFVGASFTTHFTNYSTPDNVRHGIDKSPGASLLLNYLTSRATIPEYQVRW
AWQEGDVAVWDNRSTQHYAVNDYYPAPRKMERAGIVGDIPY

Specific function: Catalyzes the conversion of taurine and alpha ketoglutarate to sulfite, aminoacetaldehyde and succinate. Required for the utilization of taurine (2-aminoethanesulfonic acid) as an alternative sulfur source. Pentane-sulfonic acid, 3- (N-morpholino)propanes

COG id: COG2175

COG function: function code Q; Probable taurine catabolism dioxygenase

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the tfdA dioxygenase family [H]

Homologues:

Organism=Escherichia coli, GI1786565, Length=295, Percent_Identity=37.2881355932203, Blast_Score=181, Evalue=7e-47,
Organism=Saccharomyces cerevisiae, GI6322971, Length=280, Percent_Identity=25.3571428571429, Blast_Score=92, Evalue=9e-20,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003819 [H]

Pfam domain/function: PF02668 TauD [H]

EC number: =1.14.11.17 [H]

Molecular weight: Translated: 31404; Mature: 31404

Theoretical pI: Translated: 7.20; Mature: 7.20

Prosite motif: NA

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.1 %Cys     (Translated Protein)
1.8 %Met     (Translated Protein)
2.8 %Cys+Met (Translated Protein)
1.1 %Cys     (Mature Protein)
1.8 %Met     (Mature Protein)
2.8 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MKIRQITPAIGAEISGVNLGEGARDPALFAEIKAALLKHRVLFFRKQEITRADHVAFASA
CCCCCCCHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKLEDHPVVGSVPDHPGLVKVYRSDNPHSYENSYHCDGLWRPNPAMGAVLRCLECPEIG
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GDTIWVNMVKAYDELPEEIKRKINGLRARASIEHSFGAVMTPENRAKLAQDHPAVEHPVV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHCCCCCCCCEE
RTHPETGEKILFVGASFTTHFTNYSTPDNVRHGIDKSPGASLLLNYLTSRATIPEYQVRW
ECCCCCCCEEEEEECCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEE
AWQEGDVAVWDNRSTQHYAVNDYYPAPRKMERAGIVGDIPY
EEECCCEEEECCCCCCEEEECCCCCCCCHHHHCCCCCCCCC
>Mature Secondary Structure
MKIRQITPAIGAEISGVNLGEGARDPALFAEIKAALLKHRVLFFRKQEITRADHVAFASA
CCCCCCCHHHCCEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
FGKLEDHPVVGSVPDHPGLVKVYRSDNPHSYENSYHCDGLWRPNPAMGAVLRCLECPEIG
HCCCCCCCCCCCCCCCCCEEEEEECCCCCCCCCCCCCCCCCCCCHHHHHHHHHHCCCCCC
GDTIWVNMVKAYDELPEEIKRKINGLRARASIEHSFGAVMTPENRAKLAQDHPAVEHPVV
CCEEEHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEECCCHHHHHHHCCCCCCCCEE
RTHPETGEKILFVGASFTTHFTNYSTPDNVRHGIDKSPGASLLLNYLTSRATIPEYQVRW
ECCCCCCCEEEEEECCCEEECCCCCCCHHHHHCCCCCCCHHHHHHHHHHCCCCCCEEEEE
AWQEGDVAVWDNRSTQHYAVNDYYPAPRKMERAGIVGDIPY
EEECCCEEEECCCCCCEEEECCCCCCCCHHHHCCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 8808933; 9278503; 2656410; 8774726; 7984428; 9287300; 11955067 [H]