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The map label for this gene is dctS [H]

Identifier: 73540996

GI number: 73540996

Start: 1392066

End: 1394681

Strand: Reverse

Name: dctS [H]

Synonym: Reut_A1302

Alternate gene names: 73540996

Gene position: 1394681-1392066 (Counterclockwise)

Preceding gene: 73541001

Following gene: 73540995

Centisome position: 36.64

GC content: 66.48

Gene sequence:

>2616_bases
ATGTCGTTTTTCGATCGTTTCCTGTCCAGCCTGCGTGCAGCCGTCGTTCCGCCCACCGCCTCCCCTACCGCGAGCTCTAC
CGCGTCCGATAGGGCCAGGGCAACCGGAGGCGACGGCGCACACGCCGCGCCGCCGGCCGGCACGCTTGGCACGATCGACA
CCATGGCACCGGTCGATGACGGTGGCACCGTCGCCGCGCCCACGCGCGGCCTGTGGTGGCTGCGCTGGCGCAACCTCGTC
GCCACGAGCTGGTTCATGTTCATCCCACTGGTGGCCATCGTGCTGTTCAGCGCGGCGATGGGCGTCATCCTCTGGTCCCT
GCACGAGACCGAGCGCCAGCAGCAGCGTGACGCGCTGTACCGCGACGCGGCCTGGGCGCAGCAACGCGTGCGGCTGTCCC
TGCTGAGCAATCAGGACCAGCTTGCCTCGCTCGCTCGCGACATTGCGGCCGCGCAGCTCGAACAGGGCGCGTACCGGACC
GCGGCGCAGGAAATCCTGCGCGAGAACCCCGAGATCGTCTTCATCAACTGGCTCGATGCTACGCGCCGGGGGCGGTGGTC
GCTGCCGTCCACGTCGGAGTTCGCGGCGCGCCTGCGCGAGAACCAGGACCAGCCGCTGGAACCCGAGGTACTCGACACCT
TCGACGCCGCGCGCGAGACCCAGCGCGTGGTCTACTCGCGCCCGCTGACCAATGACCGCGGCGACAGCTTCATGCTGATG
GAAGTGCCGATCGTCCGTGACAACGAGTTCCTCGGCACGCTCGGCGCGCTTTATTCGATCAACGGCATCCTCACGCATCT
GCTGCCGCCGGAACTGACCGAGCGCTATCGGTTCTCTCTGATCGACAAGAACAACCAGACCCGCGCCAGCACCTCGCTGC
GCCCCGTGCCCGGCAACGCGCTGTCGTACGAGGTGCTGCTCGACCCGCCGGGCCATTCGCTGTCGCTGCGCGCCGACGCG
TATCCGCCGCCGTCCAACTTGCCCAACAACATGCTGCTGTGGCTGGTGGTCGGGCTGTCGTGCTTTCTGCTATGGAGCCT
TTGGAGCATGTGGCGACACACCAGCCGCCGCTCCGAGGCGCAGCGCGCGCTGCTGGCCGAAACGTCGTTCCGGCGCGCGA
TGGAAAACTCGATGCTGATCGGCCTGCGCGCGCTGGATCTGAATGGCCGCATCACCTACGTGAATCCGGCGTTCTGCCGC
ATGACCGGCTGGCAGGAAAACGACCTGGTTGGCCGTCTGCCGCCCTTCCCCTACTGGCCGCCGAACGACCAGCAGGAAAT
GCAGCGGCAGATCGACCTCACGCTGCAGGGCAAGTCGCCGTCCGGCGGCTACGAAATGCGCGTGATGCGCCGCGACGGCA
GCAGCTTCTTCTCGCGCATGTACGTGTCGCCGCTGGTGGACAGCCGCGGCCGCCACACGGGCTGGATGAGTTCGATGACG
GACATCACCGAGCCCAAACGCGCACGCGAGGAACTGGCCGCCGCGCACGACCGCTTCACCACCGTGCTGGAAAGCCTGGA
CGCCGCGGTGTCCGTGCTGGCCACCGACAAGGCCGAGCTGCTGTTTGCTAACCGCTACTACCGCCAGCTGTTCGGCTGGG
AAGCCGAAGGCCACCTGAAACTGGCCGGAGACGAAGTCGACAAGGACCAGGTCTCGAGCGACAACACCGACTATGTCGAT
GCGTACGCCGGCCTGCCCGCCTCCGAACTGATGCCTTACACGTCGGACGCGCGCGAAGTGTTCGTACCCGATATGCAGAA
GTGGTTCGAAGTGCGCCGCCGCTACATCCAGTGGGTGGACGGCCATCTCGCGCAGATGCAGATCGCCACCGACATCACGA
TGCGCAAGGCCGCCGAGGAAATGACGCGCCAGCACGAGGAGCGCCTGCAGTTCACCAGCCGCCTGACCACCATGGGCGAG
ATGGCGTCGTCGCTCGCGCATGAGCTGAACCAGCCACTGGCCGCCATCAACAACTACTGCATGGGCGCTGTGGCGCGCCT
GCATTCGGGCCGCAGCACGCCGGAAGACCTGATCCCGGTACTGGAAAAGACGTCGGCCCAGGCCGTGCGCGCGGGCACCA
TCATCAGCCGTATCCGCGGCTTCGTGAAGCGCAGCCAGCCGCAACGGCGCGAGGCCTCGCTGCACGATATCGTGGCCGAC
GCGGTCGGCCTGGCCGACCTCGAGGCCACGCGCCGGCGCGTCACGATCCTGACGCGCCTGCCTGCCCCGCCGACGATGAT
CTACGTCGACCCGGTGCTGATCGAACAGGTATTGGTGAACCTGCTCAAGAACGCCGTCGAGGCGATGTCCGGCATGCCCG
CCCCGCGGGCGGGCGGCGTGGTGCGCCTGCACGCGCGCATCGAGCCGGGCGAGTTCGGCAACAACGTGCATATCGACGTG
ATCGACCAGGGTCCCGGCGTCGACGAAGCCACCAAGGAACGGCTGTTCGAGCCGTTCTTCAGCACCAAGTCCGACGGCAT
GGGCATGGGGCTGAATATCTGCCGCTCGATCATCGAATCCCACCAGGGCAGGCTGTGGGTCGAGAACAATGTCGACGGCA
TTGGCTGTACGTTTAAAATCATGCTGCCTCTGCAGCCGACAATGGCTGATCAGTAA

Upstream 100 bases:

>100_bases
GCCGGGACGTCAGGCATTAGCTTGATTTCATTGGCGCTTTCCCCAAGCGACGCACCGCAATAATCCCGCTACACTGCTCG
GTCAGCCGTCAATCCCTGTC

Downstream 100 bases:

>100_bases
CGACACGCGCCCGATCACGGAACTGCCGGCACCCCACGCCGGTGGGGTGCCGGATCTGTTACATAGCGCCGCGGCCGGTT
ACACTTCTGCCGCAAATGAA

Product: PAS/PAC sensor signal transduction histidine kinase

Products: NA

Alternate protein names: NA

Number of amino acids: Translated: 871; Mature: 870

Protein sequence:

>871_residues
MSFFDRFLSSLRAAVVPPTASPTASSTASDRARATGGDGAHAAPPAGTLGTIDTMAPVDDGGTVAAPTRGLWWLRWRNLV
ATSWFMFIPLVAIVLFSAAMGVILWSLHETERQQQRDALYRDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLEQGAYRT
AAQEILRENPEIVFINWLDATRRGRWSLPSTSEFAARLRENQDQPLEPEVLDTFDAARETQRVVYSRPLTNDRGDSFMLM
EVPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSLRPVPGNALSYEVLLDPPGHSLSLRADA
YPPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCR
MTGWQENDLVGRLPPFPYWPPNDQQEMQRQIDLTLQGKSPSGGYEMRVMRRDGSSFFSRMYVSPLVDSRGRHTGWMSSMT
DITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKLAGDEVDKDQVSSDNTDYVD
AYAGLPASELMPYTSDAREVFVPDMQKWFEVRRRYIQWVDGHLAQMQIATDITMRKAAEEMTRQHEERLQFTSRLTTMGE
MASSLAHELNQPLAAINNYCMGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVAD
AVGLADLEATRRRVTILTRLPAPPTMIYVDPVLIEQVLVNLLKNAVEAMSGMPAPRAGGVVRLHARIEPGEFGNNVHIDV
IDQGPGVDEATKERLFEPFFSTKSDGMGMGLNICRSIIESHQGRLWVENNVDGIGCTFKIMLPLQPTMADQ

Sequences:

>Translated_871_residues
MSFFDRFLSSLRAAVVPPTASPTASSTASDRARATGGDGAHAAPPAGTLGTIDTMAPVDDGGTVAAPTRGLWWLRWRNLV
ATSWFMFIPLVAIVLFSAAMGVILWSLHETERQQQRDALYRDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLEQGAYRT
AAQEILRENPEIVFINWLDATRRGRWSLPSTSEFAARLRENQDQPLEPEVLDTFDAARETQRVVYSRPLTNDRGDSFMLM
EVPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSLRPVPGNALSYEVLLDPPGHSLSLRADA
YPPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCR
MTGWQENDLVGRLPPFPYWPPNDQQEMQRQIDLTLQGKSPSGGYEMRVMRRDGSSFFSRMYVSPLVDSRGRHTGWMSSMT
DITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKLAGDEVDKDQVSSDNTDYVD
AYAGLPASELMPYTSDAREVFVPDMQKWFEVRRRYIQWVDGHLAQMQIATDITMRKAAEEMTRQHEERLQFTSRLTTMGE
MASSLAHELNQPLAAINNYCMGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVAD
AVGLADLEATRRRVTILTRLPAPPTMIYVDPVLIEQVLVNLLKNAVEAMSGMPAPRAGGVVRLHARIEPGEFGNNVHIDV
IDQGPGVDEATKERLFEPFFSTKSDGMGMGLNICRSIIESHQGRLWVENNVDGIGCTFKIMLPLQPTMADQ
>Mature_870_residues
SFFDRFLSSLRAAVVPPTASPTASSTASDRARATGGDGAHAAPPAGTLGTIDTMAPVDDGGTVAAPTRGLWWLRWRNLVA
TSWFMFIPLVAIVLFSAAMGVILWSLHETERQQQRDALYRDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLEQGAYRTA
AQEILRENPEIVFINWLDATRRGRWSLPSTSEFAARLRENQDQPLEPEVLDTFDAARETQRVVYSRPLTNDRGDSFMLME
VPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSLRPVPGNALSYEVLLDPPGHSLSLRADAY
PPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEAQRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRM
TGWQENDLVGRLPPFPYWPPNDQQEMQRQIDLTLQGKSPSGGYEMRVMRRDGSSFFSRMYVSPLVDSRGRHTGWMSSMTD
ITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLKLAGDEVDKDQVSSDNTDYVDA
YAGLPASELMPYTSDAREVFVPDMQKWFEVRRRYIQWVDGHLAQMQIATDITMRKAAEEMTRQHEERLQFTSRLTTMGEM
ASSLAHELNQPLAAINNYCMGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVADA
VGLADLEATRRRVTILTRLPAPPTMIYVDPVLIEQVLVNLLKNAVEAMSGMPAPRAGGVVRLHARIEPGEFGNNVHIDVI
DQGPGVDEATKERLFEPFFSTKSDGMGMGLNICRSIIESHQGRLWVENNVDGIGCTFKIMLPLQPTMADQ

Specific function: Member of the two-component regulatory system dctS/dctR involved in the transport of C4-dicarboxylates. DctS functions as a membrane-associated protein kinase that phosphorylates dctR in response to environmental signals [H]

COG id: COG2202

COG function: function code T; FOG: PAS/PAC domain

Gene ontology:

Cell location: Cell inner membrane; Multi-pass membrane protein [H]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Contains 1 PAS (PER-ARNT-SIM) domain [H]

Homologues:

Organism=Escherichia coli, GI1788549, Length=265, Percent_Identity=29.0566037735849, Blast_Score=115, Evalue=1e-26,
Organism=Escherichia coli, GI1790436, Length=247, Percent_Identity=28.3400809716599, Blast_Score=99, Evalue=9e-22,
Organism=Escherichia coli, GI1786912, Length=300, Percent_Identity=27.6666666666667, Blast_Score=81, Evalue=2e-16,
Organism=Escherichia coli, GI1790300, Length=239, Percent_Identity=29.2887029288703, Blast_Score=77, Evalue=6e-15,
Organism=Escherichia coli, GI1790346, Length=245, Percent_Identity=26.530612244898, Blast_Score=70, Evalue=5e-13,
Organism=Escherichia coli, GI145693157, Length=275, Percent_Identity=26.1818181818182, Blast_Score=70, Evalue=6e-13,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR003594
- InterPro:   IPR001610
- InterPro:   IPR000014
- InterPro:   IPR000700
- InterPro:   IPR013767
- InterPro:   IPR004358
- InterPro:   IPR003661
- InterPro:   IPR005467
- InterPro:   IPR009082 [H]

Pfam domain/function: PF02518 HATPase_c; PF00512 HisKA; PF00989 PAS [H]

EC number: =2.7.13.3 [H]

Molecular weight: Translated: 97559; Mature: 97428

Theoretical pI: Translated: 6.23; Mature: 6.23

Prosite motif: PS50112 PAS ; PS50113 PAC ; PS50109 HIS_KIN

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

0.6 %Cys     (Translated Protein)
3.7 %Met     (Translated Protein)
4.2 %Cys+Met (Translated Protein)
0.6 %Cys     (Mature Protein)
3.6 %Met     (Mature Protein)
4.1 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MSFFDRFLSSLRAAVVPPTASPTASSTASDRARATGGDGAHAAPPAGTLGTIDTMAPVDD
CCHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGTVAAPTRGLWWLRWRNLVATSWFMFIPLVAIVLFSAAMGVILWSLHETERQQQRDALY
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLEQGAYRTAAQEILRENPEIVFINWLDA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
TRRGRWSLPSTSEFAARLRENQDQPLEPEVLDTFDAARETQRVVYSRPLTNDRGDSFMLM
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
EVPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSLRPVPGNA
EECEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCC
LSYEVLLDPPGHSLSLRADAYPPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEA
EEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRMTGWQENDLVGRLPPFPYWP
HHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECHHHHEECCCCCCCCCCCCCCCCCCC
PNDQQEMQRQIDLTLQGKSPSGGYEMRVMRRDGSSFFSRMYVSPLVDSRGRHTGWMSSMT
CCCHHHHHHHCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEE
LAGDEVDKDQVSSDNTDYVDAYAGLPASELMPYTSDAREVFVPDMQKWFEVRRRYIQWVD
ECCCCCCHHHCCCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GHLAQMQIATDITMRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHELNQPLAAINNYC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVAD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AVGLADLEATRRRVTILTRLPAPPTMIYVDPVLIEQVLVNLLKNAVEAMSGMPAPRAGGV
HHHHHHHHHHHHEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VRLHARIEPGEFGNNVHIDVIDQGPGVDEATKERLFEPFFSTKSDGMGMGLNICRSIIES
EEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
HQGRLWVENNVDGIGCTFKIMLPLQPTMADQ
CCCCEEEECCCCCCCEEEEEEECCCCCCCCC
>Mature Secondary Structure 
SFFDRFLSSLRAAVVPPTASPTASSTASDRARATGGDGAHAAPPAGTLGTIDTMAPVDD
CHHHHHHHHHHHEECCCCCCCCCCCCCHHHHHCCCCCCCCCCCCCCCCCCCCCCCCCCC
GGTVAAPTRGLWWLRWRNLVATSWFMFIPLVAIVLFSAAMGVILWSLHETERQQQRDALY
CCEEECCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
RDAAWAQQRVRLSLLSNQDQLASLARDIAAAQLEQGAYRTAAQEILRENPEIVFINWLDA
HHHHHHHHHHHHHHHCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCEEEEEECCC
TRRGRWSLPSTSEFAARLRENQDQPLEPEVLDTFDAARETQRVVYSRPLTNDRGDSFMLM
CCCCCCCCCCHHHHHHHHHCCCCCCCCCHHHHHHHHHHHHHHHHHCCCCCCCCCCEEEEE
EVPIVRDNEFLGTLGALYSINGILTHLLPPELTERYRFSLIDKNNQTRASTSLRPVPGNA
EECEECCCHHHHHHHHHHHHHHHHHHCCCHHHHHHHHEEEECCCCCCCCCCCCCCCCCCC
LSYEVLLDPPGHSLSLRADAYPPPSNLPNNMLLWLVVGLSCFLLWSLWSMWRHTSRRSEA
EEEEEEECCCCCCEEEEECCCCCCCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHH
QRALLAETSFRRAMENSMLIGLRALDLNGRITYVNPAFCRMTGWQENDLVGRLPPFPYWP
HHHHHHHHHHHHHHHCCCEEEEEEEECCCEEEEECHHHHEECCCCCCCCCCCCCCCCCCC
PNDQQEMQRQIDLTLQGKSPSGGYEMRVMRRDGSSFFSRMYVSPLVDSRGRHTGWMSSMT
CCCHHHHHHHCCEEEECCCCCCCCEEEEEECCHHHHHHHHHHHHHHCCCCCCCCHHHHHH
DITEPKRAREELAAAHDRFTTVLESLDAAVSVLATDKAELLFANRYYRQLFGWEAEGHLK
HCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHHHHCCCCCCCEE
LAGDEVDKDQVSSDNTDYVDAYAGLPASELMPYTSDAREVFVPDMQKWFEVRRRYIQWVD
ECCCCCCHHHCCCCCCCHHHHHCCCCHHHCCCCCCCCCCCCCCCHHHHHHHHHHHHHHHC
GHLAQMQIATDITMRKAAEEMTRQHEERLQFTSRLTTMGEMASSLAHELNQPLAAINNYC
CHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCHHHHHHHHH
MGAVARLHSGRSTPEDLIPVLEKTSAQAVRAGTIISRIRGFVKRSQPQRREASLHDIVAD
HHHHHHHHCCCCCHHHHHHHHHHHHHHHHHHHHHHHHHHHHHHCCCCHHHHHHHHHHHHH
AVGLADLEATRRRVTILTRLPAPPTMIYVDPVLIEQVLVNLLKNAVEAMSGMPAPRAGGV
HHHHHHHHHHHHEEEEEEECCCCCCEEEECHHHHHHHHHHHHHHHHHHHCCCCCCCCCCE
VRLHARIEPGEFGNNVHIDVIDQGPGVDEATKERLFEPFFSTKSDGMGMGLNICRSIIES
EEEEEEECCCCCCCEEEEEEECCCCCCCHHHHHHHHHHHHCCCCCCCCCCHHHHHHHHHH
HQGRLWVENNVDGIGCTFKIMLPLQPTMADQ
CCCCEEEECCCCCCCEEEEEEECCCCCCCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 6.0

TargetDB status: NA

Availability: NA

References: 8455557 [H]