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The map label for this gene is lpsI [H]

Identifier: 73540964

GI number: 73540964

Start: 1354604

End: 1355305

Strand: Direct

Name: lpsI [H]

Synonym: Reut_A1269

Alternate gene names: 73540964

Gene position: 1354604-1355305 (Clockwise)

Preceding gene: 73540962

Following gene: 73540965

Centisome position: 35.59

GC content: 64.25

Gene sequence:

>702_bases
ATGAACAAGGTCTACGCCAGCGCCGCCGAGGCGCTTGCAGGCGTCGTCCGCGACGGCCAGACGATCGCCGTTGGCGGTTT
CGGCCTGTGCGGCATTCCCGAGGCGCTGATTGCTGCGCTGCGCGACACCGGCGTCAAGCAGCTCACCTGCATCTCCAACA
ACGCCGGCGTGGATGGCTTTGGCCTGGGCCAGCTGCTGGAAACACGCCAGATCAAGAAGATGATTTCGTCCTACGTGGGC
GAGAACAAGGAGTTCGAGCGCCAGTACCTGGCCGGCGAACTCGAGCTGGAATTCACGCCGCAGGGTACGCTGGCCGAGAA
GCTTCGCGCCGGTGGTTCGGGCATCCCGGCCTTCTTCACCAAGACCGGCGTGGGCACCATCGTCGCCGACGGCAAGGAAA
TTCGCGAATTCGACGGCGAGAAGTACGTGATGGAGCGTTCGCTGACCGCCGACGTGGCGCTGGTCAAGGCCTGGAAGGCC
GACAAGGCCGGCAACCTGGTGTTCCGCCGTACCGCGCGCAACTTCAACCCGATGTGCGCCATGGCGGGCAAGTTCACCGT
GGCCGAGGTCGAGCACATCGTCGAAACCGGCGAGCTTGACCCCGATGAGATCCACCTGGCTGGCATCTTCGTCAAGCGCC
TCGTGCTCAACACGACCCCCGAAAAACGCATCGAGCAGCGCACCGTGCGTGCCGCCAAGTAA

Upstream 100 bases:

>100_bases
GCAGCCGCCGCTGATTGTACCGTTACAATTTCCTTGCGTCGTGCGCCGCACACCCTTGCGGCGGGATCGGCGACGAGGGC
TACCGAGGAAGGAGCGAACC

Downstream 100 bases:

>100_bases
GAGGGAGACACATCATGGCATGGACACGTGACGAAATGGCCGCGCGCGCCGCGGCGGAGCTGCAGGACGGCTTCTATGTG
AACCTGGGTATCGGCCTGCC

Product: coenzyme A transferase

Products: NA

Alternate protein names: Succinyl CoA:3-oxoacid CoA-transferase; OXCT A [H]

Number of amino acids: Translated: 233; Mature: 233

Protein sequence:

>233_residues
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDTGVKQLTCISNNAGVDGFGLGQLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTKTGVGTIVADGKEIREFDGEKYVMERSLTADVALVKAWKA
DKAGNLVFRRTARNFNPMCAMAGKFTVAEVEHIVETGELDPDEIHLAGIFVKRLVLNTTPEKRIEQRTVRAAK

Sequences:

>Translated_233_residues
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDTGVKQLTCISNNAGVDGFGLGQLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTKTGVGTIVADGKEIREFDGEKYVMERSLTADVALVKAWKA
DKAGNLVFRRTARNFNPMCAMAGKFTVAEVEHIVETGELDPDEIHLAGIFVKRLVLNTTPEKRIEQRTVRAAK
>Mature_233_residues
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDTGVKQLTCISNNAGVDGFGLGQLLETRQIKKMISSYVG
ENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFTKTGVGTIVADGKEIREFDGEKYVMERSLTADVALVKAWKA
DKAGNLVFRRTARNFNPMCAMAGKFTVAEVEHIVETGELDPDEIHLAGIFVKRLVLNTTPEKRIEQRTVRAAK

Specific function: SHORT-CHAIN FATTY ACIDS METABOLISM. [C]

COG id: COG1788

COG function: function code I; Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit

Gene ontology:

Cell location: Cytoplasm [C]

Metaboloic importance: Non_Essential [C]

Operon status: Not Known

Operon components: None

Similarity: Belongs to the 3-oxoacid CoA-transferase subunit A family [H]

Homologues:

Organism=Homo sapiens, GI4557817, Length=247, Percent_Identity=56.2753036437247, Blast_Score=280, Evalue=8e-76,
Organism=Homo sapiens, GI11545841, Length=246, Percent_Identity=53.2520325203252, Blast_Score=245, Evalue=3e-65,
Organism=Escherichia coli, GI1788551, Length=205, Percent_Identity=42.4390243902439, Blast_Score=187, Evalue=5e-49,
Organism=Caenorhabditis elegans, GI17531517, Length=245, Percent_Identity=55.5102040816327, Blast_Score=262, Evalue=9e-71,
Organism=Drosophila melanogaster, GI21358325, Length=250, Percent_Identity=53.6, Blast_Score=256, Evalue=1e-68,
Organism=Drosophila melanogaster, GI24655794, Length=250, Percent_Identity=53.6, Blast_Score=255, Evalue=1e-68,

Paralogues:

None

Copy number: NA

Swissprot (AC and ID): NA

Other databases:

- InterPro:   IPR012792
- InterPro:   IPR004165
- InterPro:   IPR004163 [H]

Pfam domain/function: PF01144 CoA_trans [H]

EC number: =2.8.3.5 [H]

Molecular weight: Translated: 25196; Mature: 25196

Theoretical pI: Translated: 7.35; Mature: 7.35

Prosite motif: PS01273 COA_TRANSF_1

Important sites: NA

Signals:

None

Transmembrane regions:

None

Cys/Met content:

1.3 %Cys     (Translated Protein)
2.1 %Met     (Translated Protein)
3.4 %Cys+Met (Translated Protein)
1.3 %Cys     (Mature Protein)
2.1 %Met     (Mature Protein)
3.4 %Cys+Met (Mature Protein)

Secondary structure:

>Translated Secondary Structure
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDTGVKQLTCISNNAGVDGF
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCC
GLGQLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTIVADGKEIREFDGEKYVMERSLTADVALVKAWKADKAGNLVFRRTARNFNPMCA
HCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKFTVAEVEHIVETGELDPDEIHLAGIFVKRLVLNTTPEKRIEQRTVRAAK
HCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC
>Mature Secondary Structure
MNKVYASAAEALAGVVRDGQTIAVGGFGLCGIPEALIAALRDTGVKQLTCISNNAGVDGF
CCCHHHHHHHHHHHHHCCCCEEEECCCCCCCHHHHHHHHHHHCCCEEEEEECCCCCCCCC
GLGQLLETRQIKKMISSYVGENKEFERQYLAGELELEFTPQGTLAEKLRAGGSGIPAFFT
CHHHHHHHHHHHHHHHHHHCCCHHHHHHHHCCEEEEEECCCCHHHHHHHCCCCCCCHHHH
KTGVGTIVADGKEIREFDGEKYVMERSLTADVALVKAWKADKAGNLVFRRTARNFNPMCA
HCCCCEEEECCHHHHHCCCCHHHHHHHHHHHHHHHHHHCCCCCCCEEEEECCCCCCCHHH
MAGKFTVAEVEHIVETGELDPDEIHLAGIFVKRLVLNTTPEKRIEQRTVRAAK
HCCCCHHHHHHHHHHHCCCCHHHHHHHHHHHHHHHHCCCHHHHHHHHHHHCCC

PDB accession: NA

Resolution: NA

Structure class: Unstructured

Cofactors: NA

Metal ions: NA

Kcat value (1/min): NA

Specific activity: NA

Km value (mM): NA

Substrates: NA

Specific reaction: NA

General reaction: NA

Inhibitor: NA

Structure determination priority: 10.0

TargetDB status: NA

Availability: NA

References: 9385134; 11589581 [H]